检索结果-南通市图书馆

Colonoscopy surveillance for high risk polyps does not always prevent colorectal cancer

World Journal of Gastroenterology 2018年第8期24卷 905-916页

作者： Mohamad A Mouchli lidia ouk Marianne R Scheitel Alisha P Chaudhry Donna Felmlee-Devine Diane E Grill Shahrooz Rashtak Panwen Wang Junwen Wang Rajeev Chaudhry Thomas C Smyrk Ann L Oberg Brooke R Druliner Lisa A Boardman Division of Gastroenterology and Hepatology Mayo Clinic Knowledge and Delivery Center Mayo Clinic Biostatistics and Bioinformatics Health Sciences Research Mayo Clinic Division of Biomedical Statistics and Informatics Health Sciences Research Mayo Clinic Biostatistics and Bioinformatics Health Science Research Center for Individualized Medicine Mayo Clinic Department of Biomedical Informatics Arizona State University Primary Care Internal Medicine Mayo Clinic Center for Innovation Mayo Clinic Department of Laboratory Medicine and Pathology Mayo Clinic

AIM To determine the frequency and risk factors for colorectal cancer(CRC) development among individuals with resected advanced adenoma(AA)/traditional serrated adenoma(TSA)/advanced sessile serrated adenoma(ASSA). METHODS Data was collected from medical records of 14663 subjects found to have AA, TSA, or ASSA at screening or surveillance colonoscopy. Patients with inflammatory bowel disease or known genetic predisposition for CRC were excluded from the study. Factors associated with CRC developing after endoscopic management of high risk polyps were calculated in 4610 such patients who had at least one surveillance colonoscopy within 10 years following the original polypectomy of the incident advanced polyp. RESULTS84/4610(1.8%) patients developed CRC at the polypectomy site within a median of 4.2 years(mean 4.89 years), and 1.2%(54/4610) developed CRC in a region distinct from the AA/TSA/ASSA resection site within a median of 5.1 years(mean 6.67 years). Approximately, 30%(25/84) of patients who developed CRC at the AA/TSA/ASSA site and 27.8%(15/54) of patients who developed CRC at another site had colonoscopy at recommended surveillance intervals. Increasing age; polyp size; male sex; right-sided location; high degree of dysplasia; higher number of polyps resected; and piecemeal removal were associated with an increased risk for CRC developmentat the same site as the index polyp. Increasing age; right-sided location; higher number of polyps resected and sessile endoscopic appearance of the index AA/TSA/ASSA were significantly associated with an increased risk for CRC development at a different site. CONCLUSION Recognition that CRC may develop following AA/TSA/ASSA removal is one step toward improving our practice efficiency and preventing a portion of CRC related morbidity and mortality.

关键词： Colon cancer Rectal Cancer Advanced adenoma Sessile serrated adenoma High risk polyps Post-polypectomy colorectal cancer

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

High Performance Classification of Android Malware Using Ensemble Machine Learning

引用

Computers, Materials & Continua 2022年第7期72卷 381-398页

作者： Pagnchakneat C.ouk Wooguil Pak Department of Computer Engineering Keimyung UniversityDaegu42601Korea Department of Information and Communication Engineering Yeungnam UniversityGyeongsanGyeongbuk38541Korea

Although Android becomes a leading operating system in market,Android users suffer from security threats due to *** protect users from the threats,the solutions to detect and identify the malware variant are ***,modern malware evades existing solutions by applying code obfuscation and native *** resolve this problem,we introduce an ensemble-based malware classification algorithm using malware family *** proposed family grouping algorithm finds the optimal combination of families belonging to the same group while the total number of families is fixed to the optimal total *** also adopts unified feature extraction technique for handling seamless both bytecode and native *** propose a unique feature selection algorithm that improves classification performance and time simultaneously.2-gram based features are generated from the instructions and segments,and then selected by using multiple filters to choose most effective *** extensive simulation with many obfuscated and native code malware applications,we confirm that it can classify malwares with high accuracy and short processing *** existing approaches failed to achieve classification speed and detection time ***,the approach can help Android users to keep themselves safe from various and evolving cyber-attacks very effectively.

关键词： Android malware classification family grouping native code obfuscation unified feature extraction

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Unified Detection of Obfuscated and Native Android Malware

引用

Computers, Materials & Continua 2022年第2期70卷 3099-3116页

The Android operating system has become a leading smartphone platform for mobile and other smart devices,which in turn has led to a diversity of malware *** amount of research on Android malware detection has increased significantly in recent years and many detection systems have been *** these efforts,however,most systems can be thwarted by sophisticated Androidmalware adopting obfuscation or native code to avoid discovery by anti-virus *** this paper,we propose a new static analysis technique to address the problems of obfuscating and native malware *** proposed system provides a unified technique for extracting features from applications and native libraries using a selection algorithm that can extract a small set of unique and effective features for detecting malware applications rapidly and with a high detection *** using large Android malware detection datasets obtained from various sources confirmed that the proposed approach achieves very promising results in terms of improved accuracy,low false positive rate,and high detection rate.

关键词： Android malware detection native code obfuscation unified feature extraction

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rapid detection of influenza A(H1N1)virus by conductive polymer-based nanoparticle via optical response to virus-specific binding

引用

Nano Research 2022年第3期15卷 2254-2262页

作者： Geunseon Park Hyun-ouk Kim Jong-Woo Lim Chaewon Park Minjoo Yeom Daesub Song Seungjoo Haam Department of Chemical&Biomolecular Engineering Yonsei UniversitySeoul 03722Republic of Korea Division of Chemical Engineering and Bioengineering College of Art Culture and EngineeringKangwon National UniversityChuncheon-siGangwon-do 24341Republic of Korea Biohealth-machinery Convergence Engineering Kangwon National UniversityChuncheonGangwon-do 24341Republic of Korea College of Pharmacy Korea UniversitySejong 30019Republic of Korea

A recurrent pandemic with unpredictable viral nature has implied the need for a rapid diagnostic technology to facilitate timely and appropriate countermeasures against viral *** this study,conductive polymer-based nanoparticles have been developed as a tool for rapid diagnosis of influenza A(H1N1)*** distinctive property of a conductive polymer that transduces stimulus to respond,enabled immediate optical signal processing for the specific recognition of H1N1 *** poly(aniline-co-pyrrole)-encapsulated polymeric vesicles,functionalized with peptides,were fabricated for the specific recognition of H1N1 *** low solubility of conductive polymers was successfully improved by employing vesicles consisting of amphiphilic copolymers,facilitating the viral titer-dependent production of the optical *** optical response of the detection system to the binding event with H1N1,a mechanical stimulation,was extensively analyzed and provided concordant information on viral titers of H1N1 virus in 15 *** specificity toward the H1N1 virus was experimentally demonstrated via a negative optical response against the control group,***,the designed system that transduces the optical response to the target-specific binding can be a rapid tool for the diagnosis of H1N1.

关键词： influenza A(H1N1)virus conductive polymer optical property rapid detection

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A minimal gauge inflation model

引用

Chinese Physics C 2018年第9期42卷 109-114页

作者： Jinn-ouk Gong Seong Chan Park Korea Astronomy and Space Science Institute Daejeon 34055Korea Department of Physics and IPAP Yonsei UniversitySeoul 03722Korea

In this paper, we present a gauge inflation model based on the orbifold M4×S1/Z2 with non-Abelian SU（2） gauge symmetry, which is probably the simplest model in this category. As the inflaton potential is fully radiatively generated exclusively by gauge self-interactions, the model is predictive; thus, it is protected by gauge symmetry itself, without the introduction of any additional matter fields or arbitrary interactions. We show that the model fully agrees with the recent cosmological observations within the controlled perturbative regime of gauge interactions, g4≤1/（2πRMP）, with the compactification radius（10 ≤ RMP ≤ 100）： the expected magnitude of the curvature perturbation power spectrum and the value of the corresponding spectral index are in perfect agreement with the recent observations. The model also predicts a large fraction of the gravitational waves, negligible nonGaussianity, and a sufficiently high reheating temperature.

关键词： inflation non-Gaussianity extra dimension

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Hydrogen Generation from the Dissociation of Water Using Microwave Plasmas

引用

Chinese Physics Letters 2013年第6期30卷 144-147页

作者： Yong Ho Jung Soo ouk Jang Hyun Jong You Plasma Technology Research Center National Fusion Research InstituteJeonbuk 573-540Korea

Hydrogen is produced by direct dissociation of water vapor,i.e.,splitting water molecules by the electrons in water plasma at low pressure(<10–50 Torr)using microwave plasma *** condition generates a high electron temperature,which facilitates the direct dissociation of water molecules.A microwave plasma source is developed,utilizing the magnetron of a microwave oven and a TE10 rectangular *** quantity of the generated hydrogen is measured using a residual gas *** electron density and temperature are measured by a Langmuir probe,and the neutral temperature is calculated from the OH line intensity.

关键词： microwave dissociation utilizing

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

AMPD3 is involved in anthrax LeTx-induced macrophage cell death

引用

Protein & Cell 2011年第7期2卷 564-572页

作者： Sangun Lee Yanhai Wang Sung ouk Kim Jiahuai Han Department of Immunology and Microbial Science The Scripps Research Institute10550 North Torrey Pine RoadLa JollaCA 92037USA The State Key Laboratory of Cellular Stress Biology School of Life SciencesXiamen UniversityXiamen 361005China Current address Department of Biomedical Sciences Tufts UniversityCummings School of Veterinary MedicineNorth GraftonMassachusetts 01536USA Current address Department of Microbiology and Immunology Siebens-Drake Research InstituteUniversity of Western OntarioLondonOntarioCanada

The responses of macrophages to Bacillus anthracis infection are important for the survival of the host,since macrophages are required for the germination of *** spores in lymph nodes,and macrophage death exacerbates anthrax lethal toxin(LeTx)-induced organ *** elucidate the mechanism of macrophage cell death induced by LeTx,we performed a genetic screen to search for genes associated with LeTx-induced macrophage cell ***264.7 cells,a macrophage-like cell line sensitive to LeTx-induced death,were randomly mutated and LeTx-resistant mutant clones were *** deaminase 3(AMPD3),an enzyme that converts AMP to IMP,was identified to be mutated in one of the resistant *** requirement of AMPD3 in LeTxinduced cell death of RAW 264.7 cells was confirmed by the restoration of LeTx sensitivity with ectopic reconstitution of AMPD3 ***3 deficiency does not affect LeTx entering cells and the cleavage of mitogen-activated protein kinase kinase(MKK)by lethal factor inside cells,but does impair an unknown downstream event that is linked to cell *** data provides new information regarding LeTx-induced macrophage death and suggests that there is a key regulatory site downstream of or parallel to MKK cleavage that controls the cell death in LeTx-treated macrophages.

关键词： AMP deaminase 3 anthrax lethal toxin macrophage cell death

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Adsorption and photocatalytic degradation of bisphenol A using TiO2 and its separation by submerged hollowfiber ultrafiltration membrane

引用

Journal of Environmental Sciences 2006年第1期18卷 193-200页

作者： Jae-Wook Lee Tae-ouk Kwon Ramesh Thiruvenkatachari Il-Shik Moon Department of Chemistry Engineer Seonam University Namwon 590-711 Korea Department of Chemistry Engineer Sunchon National University Suncheon 540-742 Korea

This study evaluates the adsorption ability ofbisphenol A（BPA） on titanium dioxide（TiO2） and its effect on the photocatalysis by advanced oxidation process using UV radiation and TiO2 photocatalyst. Degradation of BPA was also evaluated for the system without adsorption prior to photocatalytic reaction. The separation of TiO2 from BPA solution treated by pilot-scale photocatalytic reactor （capacity 0.16 m^3） was studied using submerged ultrafiltration （UF） membrane. It was found that although adsorption capacity of BPA was not high, adsorption played an important role in improving the efficiency ofphotocatalysis. On the other hand, during the separation of TiO2 particles from aqueous suspension, the permeate flux of the membrane was strongly affected by transmembrane pressure and TiO2 dose. The permeate turbidity was decreased below 1 NTU.

关键词： bisphenol A TiO2 adsorption membrane photocatalysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Discovery of Single-Atom Catalyst:Customized Heteroelement Dopants on Graphene

引用

Accounts of Materials Research 2021年第6期2卷 394-406页

作者： In Ho Kim Joonwon Lim Sang ouk Kim National Creative Research Initiative Center for Multi-Dimensional Directed Nanoscale Assembly Department of Materials Science and Engineeringand KAIST Institute for NanocenturyKAISTDaejeon 34141Republic of Korea Department of Information Display Kyung Hee UniversitySeoul 02447Republic of Korea

CONSPECTUS:Single-atomic catalyst(SAC)incorporated in graphene plays an increasingly significant role in many applications,including sustainable energy conversion/storage and environmental *** a synergistic structure commonly consisting of atomic metal active sites stabilized on a robust graphene support,is breaking through the intrinsic limitations of precious-metalbased catalysts and broadening a spectrum of applications,while attaining high atom utilization,remarkable novel catalytic activity,and conformational *** from the unprecedented attractive features of SAC in graphene,enormous research efforts have been devoted to the development of this ultimate catalytic *** the further advance and eventual success in this field,a general rule for the rational design of SAC is the first ***,the research effort for the exploration of the fundamental reaction mechanism and rational design principle has been frequently overlooked in spite of the significantly accumulated research efforts thus *** this Account,we highlight a new perspective for the rational design of SAC in graphene,conceptually centered on the atomistic level heteroelement dopants of *** provide the intuitive viewpoint on the SAC from the scientific perspective,we suggest a new classification scheme for versatile SACs reported thus far into“dopant catalyst”and“dopant-assisted catalyst”,based on the detailed role of dopant in the catalyst ***,we highlight the crucial influencing factors on the catalytic activity of the dopant-induced-catalyst system and toward rational designing rule for high performance *** recent progress in the dopantinduced-catalyst system for a wide spectrum of catalytic applications,including oxygen reduction,oxygen evolution,hydrogen evolution,and CO_(2)reduction is ***,we briefly discuss the challenges and opportunities for the future research *** exciting expectation

关键词： catalyst rational element

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Metabolic syndrome, lifestyle risk factors, and distal colon adenoma: A retrospective cohort study

引用

World Journal of Gastroenterology 2011年第35期17卷 4031-4037页

作者： Moon-Chan Kim Chang-Sup Kim Tae-Heum Chung Hyoung-ouk Park Cheol-In Yoo Department of Family Medicine Ulsan University Hospital University of Ulsan College of Medicine Ulsan 682-714 South Korea Department of Occupational and Environmental Medicine Ulsan University Hospital

AIM: To investigate relationships between colorectal adenoma incidence, metabolic syndrome (MS) components and lifestyle factors. METHODS: We conducted a retrospective cohort study using data from individuals who had multiple sigmoidoscopies for colon cancer at the Health Promotion Center of Ulsan University Hospital in Korea from 1998 to 2007. RESULTS: By multivariate analysis, the incidence of distal colon adenoma was increased by more than 1.76 times in individuals with at least one component of MS compared to those without a component of MS. After adjustment for age, gender, smoking, drinking, and physical exercise, only high body mass index (BMI) was significantly associated with the incidence of distal colon adenoma (Hazard ratio 1.66, 95% confidence interval 1.05-2.62). CONCLUSION: Our results suggest that high BMI may increase the risk of colorectal adenoma in Korean adults.

关键词：代谢综合征危险因素生活方式队列研究肠腺远端综合症组成部分

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：