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Motor symptom machine rating system for complete MDS-UPDRS III in Parkinson’s disease:A proof-of-concept pilot study

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Chinese Medical Journal 2024年第13期137卷 1632-1634页

作者： Xue Zhu Zhonglue Chen Yun Ling Ningdi Luo Qianyi Yin Yichi Zhang Aonan Zhao Guanyu Ye Haiyan zhou Jing Pan liche zhou Linghao Cao Pei Huang Pingchen Zhang Cheng Chen Weikun Shi Shinuan Lin Haimei Zhuang Jin Zhao Kang Ren Yuyan Tan Jun Liu Department of Neurology and Institute of Neurology Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China GYENNO Science Co. Ltd.Nanshan DistrictShenzhenGuangdong 518100China HUST-GYENNO CNS Intelligent Digital Medicine Technology Center WuhanHubei 430074China School of Artificial Intelligence and Automation Huazhong University of Science and TechnologyWuhanHubei 430074China CAS Center for Excellence in Brain Science and Intelligence Technology Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China

To the Editor:Parkinson’s disease(PD)is one of the most common neurodegenerative movement disorders.[1]The severity of PD-related motor symptoms is usually semiquantitatively(“normal”,“slight”,“mild”,“moderate”,and“severe”)evaluated by expert physicians according to the Movement Disorder Society-sponsored revision of the Unified Parkinson’s Disease Rating Scale Part III(MDS-UPDRS III).[2]However,the MDS-UPDRS III is semiquantitative and subjective,which might mask mild treatment effects or even provide false-positive results.

关键词： MDS proof severity

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维普期刊数据库

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Contactless evaluation of rigidity in Parkinson’s disease by machine vision and machine learning

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Chinese Medical Journal 2023年第18期136卷 2254-2256页

作者： Xue Zhu Weikun Shi Yun Ling Ningdi Luo Qianyi Yin Yichi Zhang Aonan Zhao Guanyu Ye Haiyan zhou Jing Pan liche zhou Linghao Cao Pei Huang Pingchen Zhang Zhonglue Chen Cheng Chen Shinuan Lin Jin Zhao Kang Ren Yuyan Tan Jun Liu Department of Neurology and Institute of Neurology Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China GYENNO SCIENCE CO. LTD.ShenzhenGuangdong 518000China HUST-GYENNO CNS Intelligent Digital Medicine Technology Center WuhanHubei 430074China School of Artificial Intelligence and Automation Huazhong University of Science and TechnologyWuhanHubei 430074China Co-innovation Center of Neuroregeneration Nantong UniversityNantongJiangsu 226019China

To the Editor:Parkinson’s disease(PD)is one of the most common neurodegenerative movement disorders.[1]Its cardinal symptoms include bradykinesia,tremor,and rigidity.[2]The severity of PD-related motor symptoms is usually semiquantitatively evaluated by the Movement Disorder Society-sponsored revision of the Unified Parkinson’s Disease Rating Scale(MDS-UPDRS)[3]part three(MDS-UPDRS III).A series of machine perception and machine learning technologies have been applied to assist the manual rating of motor symptoms.[4,5]Machine vision,which does not require physical contact between the examiner and the patient.

关键词： rigidity severity tremor

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维普期刊数据库

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CRYSTAL AND MOLECULAR STRUCTURE OF（μ-PhCH2S）（μ-CH3C（0）CH2S）Fe2（CO）6

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结构化学 1988年第1期 53-56页

作者： Song liche.ng Hu QingmeiDepartment of Chemistry, Nankai University, Tianjinzhou Zhongyuan Xiang ZaiyunChengdu Center of Analysis and Determination, Academia Sinica

The crystal and molecular structures of (μ-PhCH2S)(μ-CH3C(O)CH2S)-Fe2(CO)6 have been determined by X-ray diffraction technique. The complex has chemical formula of C16H12O7S2Fe2 and Mr=492.08. The crystals are tri-clinic, space group P1,with a=8.461(5), b=10.937(5), c=ll.419(4)A,α=81.61 (3), β=78.21(4),γ=71.04(4)°,V=974.5A3, Dc=1.68 gcm-3,μ(MoKα)=17.3cm-1, Z=2,F(000)=495.93. The final R was 0.038 for 2874 independent reflections.

关键词： Fe PhCH2S CRYSTAL AND MOLECULAR STRUCTURE OF CH3C CO

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