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垂体后叶素辅助治疗支气管扩张合并大咯血的临床疗效和安全性分析

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中国社区医师 2020年第6期36卷 62-63页

作者：杨红丽黎秋芬徐力超仁寿县人民医院感染科

目的:探析垂体后叶素辅助治疗支气管扩张合并大咯血的临床疗效和安全性。方法:2017年3月-2019年4月收治支气管扩张合并大咯血患者90例,随机分为三组各30例。分别给予A组12 U、B组16 U、C组18 U不同剂量的垂体后叶素治疗。比较三组临床... 详细信息

目的:探析垂体后叶素辅助治疗支气管扩张合并大咯血的临床疗效和安全性。方法:2017年3月-2019年4月收治支气管扩张合并大咯血患者90例,随机分为三组各30例。分别给予A组12 U、B组16 U、C组18 U不同剂量的垂体后叶素治疗。比较三组临床疗效和不良反应发生率。结果:C组治疗总有效率显著高于A组和B组,不良反应发生率高于A组和B组,差异均有统计学意义(P<0.05)。结论:在支气管扩张合并大咯血治疗中,应用18 U垂体后叶素辅助治疗能够起到良好的效果,但不良反应发生率也随之增加,需斟酌使用。

关键词：垂体后叶素辅助治疗支气管扩张大咯血临床疗效安全性

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论提高高职院校军事理论课教学质量的对策

常州信息职业技术学院学报 2015年第5期14卷 47-49页

作者：徐丽超吴小平周劼阮兴卫常州信息职业技术学院江苏常州213164

军事理论课作为普通高等职业院校国防教育的必修课程,是培养具有现代国防意识的高素质人才的需要,提高军事理论课堂教学质量是摆在军事理论教学工作者面前的重要课题。加强军事理论教师队伍的建设、运用有效方法提高军事理论课堂教学质... 详细信息

军事理论课作为普通高等职业院校国防教育的必修课程,是培养具有现代国防意识的高素质人才的需要,提高军事理论课堂教学质量是摆在军事理论教学工作者面前的重要课题。加强军事理论教师队伍的建设、运用有效方法提高军事理论课堂教学质量,增强课堂教学效果、提高学生的学习热情,是保证军事理论课堂教学质量的关键所在。

关键词：高职院校军事理论课教学质量

慢阻肺合并肺结核患者血清细胞因子水平变化与意义研究

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实用心脑肺血管病杂志 2019年第S1期27卷 117-119页

作者：杨红丽黎秋芬徐力超四川省眉山市仁寿县人民医院感染科

目的分析慢阻肺合并肺结核患者血清细胞因子水平变化情况。方法选择四川省眉山市仁寿县人民医院2011年1月—2016年12月中的50例慢阻肺合并肺结核患者视作观察组,另外选取50例单纯慢阻肺患者视作对照1组,50例健康受检者视作对照2组,均进... 详细信息

目的分析慢阻肺合并肺结核患者血清细胞因子水平变化情况。方法选择四川省眉山市仁寿县人民医院2011年1月—2016年12月中的50例慢阻肺合并肺结核患者视作观察组,另外选取50例单纯慢阻肺患者视作对照1组,50例健康受检者视作对照2组,均进行白介素(IL-6)、干扰素(IFN-γ)、肿瘤坏死因子(TNF-α)各项血清细胞因子水平测定,分析结果。结果观察组患者血清细胞因子TNF-α、IFN-γ、IL-6指标水平分别为(89.58±32.46)ng/L、(37.48±15.69)ng/L、(70.15±32.46)ng/L,均高于单纯慢阻肺的对照1组、健康者对照2组,单纯慢阻肺的对照1组各项指标水平也明显高于健康者的对照2组(P<0.05);观察组痰菌阳性患者的细胞因子TNF-α、IFN-γ、IL-6水平均明显高于痰菌阴性患者,P<0.05;观察组治疗后血清细胞因子TNF-α、IFN-γ、IL-6指标水平分别为(60.38±15.48)ng/L、(22.35±10.46)ng/L、(48.42±16.92)ng/L,明显低于治疗前(P<0.05)。结论慢阻肺合并肺结核患者血清细胞因子水平会有明显升高,通过测定血清细胞因子水平有助于帮助临床辅助诊断慢阻肺合并肺结核,有重要应用价值。

关键词：慢阻肺肺结核血清细胞因子变化意义

基于大数据的车用动力电池开路电压估计方法研究

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汽车文摘 2022年第4期 24-29页

作者：潘垂宇李雪许立超张志陈雷中国第一汽车股份有限公司新能源开发院长春130013 汽车振动噪声与安全控制综合技术国家重点实验室长春130013

开路电压是电动汽车动力电池的重要参数之一,对电池电量(SOC)参数的估计具有关键作用。然而,在电动汽车实际使用过程中,动力电池的稳定开路电压状态却往往很难得到。传统的试验获取开路电压的方法难以满足动力电池复杂的实际工况条件。... 详细信息

开路电压是电动汽车动力电池的重要参数之一,对电池电量(SOC)参数的估计具有关键作用。然而,在电动汽车实际使用过程中,动力电池的稳定开路电压状态却往往很难得到。传统的试验获取开路电压的方法难以满足动力电池复杂的实际工况条件。为准确获取实车动力电池的开路电压值,通过大数据分析电动汽车在充电完成状态及下次启动状态的动力电池电压状况,利用随机森林回归(RFR)算法预测动力电池电压变化特性,实现了对充电完成状态的开路电压预估,估计精度可以达到87%,为SOC标定、电池等效电路参数辨识和SOH估计工作实现奠定了基础。

关键词：动力电池大数据充电电压恢复率开路电压

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MR导引聚焦超声术姑息性治疗骨转移瘤疼痛近期效果和安全性初步研究

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介入放射学杂志 2018年第7期27卷 636-640页

作者：王升平孙志荣信超杜春春许立超顾雅佳李文涛彭卫军复旦大学附属肿瘤医院(复旦大学上海医学院肿瘤学系)放射诊断科上海200032 复旦大学附属肿瘤医院(复旦大学上海医学院肿瘤学系)麻醉科上海200032 复旦大学附属肿瘤医院(复旦大学上海医学院肿瘤学系)介入科上海200032

目的评价MR导引聚焦超声术(MRg FUS)姑息性治疗其它治疗手段无效或不可行的骨转移瘤疼痛患者近期效果和安全性。方法对21例症状性骨转移患者进行前瞻性研究。根据术后3个月内手术相关并发症发生率和严重程度评估治疗安全性。根据疼痛数... 详细信息

目的评价MR导引聚焦超声术(MRg FUS)姑息性治疗其它治疗手段无效或不可行的骨转移瘤疼痛患者近期效果和安全性。方法对21例症状性骨转移患者进行前瞻性研究。根据术后3个月内手术相关并发症发生率和严重程度评估治疗安全性。根据疼痛数字评价量表(NRS)评分、简明疼痛问卷-生存质量量表(BPI-QOL)评分、Karnofsky行为状态评分(KPS)和患者用药变化评价疼痛缓解效果。结果 21例症状性骨转移患者完成MRg FUS治疗。术前1周,术后1周、1个月、2个月、3个月NRS评分分别为7.7±1.6、3.6±2.6、3.9±3.2、4.3±3.3、3.7±2.7,术后各随访时间点NRS评分均显著下降,与术前评分差异均有统计学意义(P<0.05)。BPI-QOL评分术前1周(27.3±20.9)与术后1周(34.1±15.5)、1个月(32.3±19.2)、2个月(31.9±18.9)、3个月(28.8±14.8)间差异均无统计学意义(P值分别为0.24、0.45、0.48、0.81)。KPS评分术前1周(82.2±8.8)与术后1周(84.8±7.5)、3个月(84.8±7.5)间差异均无统计学意义(P值分别为0.64、0.33)。结论 MRg FUS姑息性治疗骨转移疼痛近期效果确切,技术安全,有望成为骨转移疼痛治疗的一种有前途的替代手段。

关键词：骨肿瘤磁共振成像介入性高强度聚焦超声消融疼痛缓解

Effects of enrichmemt planting with native tree species on bacterial community structure and potential impact on Eucalyptus plantations in southern China

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Journal of Forestry Research 2022年第4期33卷 1349-1363页

作者： Yuxing xu Chao Li Wankuan Zhu Zhichao Wang lichao Wu Apeng Du Key Laboratory of Soil and Water Conservation and Desertifi cation Combating of Hunan Province College of ForestryCentral South University of Forestry and TechnologyChangshaHunan 410004People’s Republic of China China Eucalypt Research Centre(CERC) Chinese Academy of Forestry(CAF)ZhanjiangGuangdong 524022People’s Republic of China Guangdong Zhanjiang Eucalyptus Plantation Ecosystem Research Station ZhanjiangGuangdong 524022People’s Republic of China

Multi-generational planting of Eucalyptus species degrades soil quality but the introduction of legumes can improve soil fertility and microbial ***,the effects of introducing non-legume native tree species on soil nutrients and bacterial community structure remain poorly *** study investigated the impacts of the conversion of third generation monoculture Eucalyptus plantations to mixed systems including Eucalyptus urograndis with Cinnamomum camphora(EC)and *** with Castanopsis hystrix(EH),on soil chemical and biochemical properties and bacterial community structure,diversity and *** generation *** plantations were the *** show that planting the third generation Eucalyptus led to a significant decrease in p H,organic matter,nutrient content,enzyme activities(invertin,acid phosphataes,and urease),and bacterialα-diversity compare to the ***,the mixed planting showed significant improvement in soil chemical and biochemical attributes and bacterialα-diversity,although the *** and *** planting had no ***(oligotrophic bacteria)were significantly enriched in third generation Eucalyptus and Eucalyptus+***,while proteobacteria increased significantly in the *** with *** *** relative abundance of multiple metabolic pathways increased significantly in the third generation Eucalyptus plantations whereas membrane transportrelated genes were enriched in soils of the mixed *** changes in bacterial community structures in the two mixed systems were driven by diversity,organic matter and acid phosphatase,while bacterial functions were affected by invertase,NO_(3)^(-)-N,diversity and *** results suggest that the transformation of successive monoculture Eucalyptus plantations into mixed plantations reduces the depletion of soil nutrients and enhances the ecological function of soil microorganisms.

关键词： Soil chemical propertie Enzyme activity 16S rRNA amplicon sequencing Bacterial community structure Tax4Fun function prediction

Insights into thermodynamic performance of a hypersonic precooled air-breathing engine with a complicated multi-branch closed cycle

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Chinese Journal of Aeronautics 2024年第8期37卷 106-123页

作者： Yifan WANG Zhengping ZOU Pengcheng DU lichao YAO Huoxing LIU Yusen xu Research Institute of Aero-Engine Beihang UniversityBeijing 102206China National Key Laboratory of Science and Technology on Aero-Engine and Aero-Thermodynamics Beihang UniversityBeijing 102206China

An advanced precooled airbreathing engine with a closed Brayton cycle is a promising solution for high-speed propulsion,of which the Synergetic Air Breathing Rocket Engine(SABRE)is a representative *** performance of the latest SABRE-4 cycle was analyzed in this ***,a relatively complete engine performance model that considers the characteristics of turbomachinery and heat exchangers was ***,Sobol’global sensitivity analysis of key performance parameters was carried out to identify the most influential design *** specific impulses under different target specific thrusts were obtained by particle swarm optimization,of which the thermodynamic parameters corresponding to a specific thrust of 1.12 kN·s·kg^(-1)and a specific impulse of 3163 s were chosen as the design *** different control laws were analyzed in contrast,and the charge control method had the strongest ability of thrust regulation as well as maintaining a favorable specific impulse ***,working characteristics under the charge control and over a typical flight envelope were calculated,in which the average value of the maximum specific impulse was as high as 5315 *** study would help to deepen the understanding of SABRE-4 thermodynamic characteristics and other precooled airbreathing engine cycles with similar layouts.

关键词： Hypersonic Precooled airbreathing engine Thermodynamic cycle Control law Working characteristics

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鱼骨刺水平井改善高阶煤低产区开发效果研究

中国煤炭地质 2017年第7期29卷 36-39,45页

作者：范书军许立超董建秋彭鹤曹原中国石油与天然气股份有限公司华北油田山西煤层气勘探开发分公司晋城048000

目前高庄区块采用的开发方案主要为直井钻井、水力压裂增产开发方式及油管排液、套管采气的抽油机排采工艺,但产气效果不甚理想。面对高庄区块东部高含气量、低渗透率导致的低产井集中、自然上产能力差的现状,借鉴苏庄区块开发经验,采... 详细信息

目前高庄区块采用的开发方案主要为直井钻井、水力压裂增产开发方式及油管排液、套管采气的抽油机排采工艺,但产气效果不甚理想。面对高庄区块东部高含气量、低渗透率导致的低产井集中、自然上产能力差的现状,借鉴苏庄区块开发经验,采用逆向思维在高庄区块低产直井井区部署新型鱼骨刺水平井。这种新型水平井设计在煤层中钻探多个水平分支,提高了井区煤层的渗透率和连通性,有效解决高庄区块东部区域含气量高但渗透率低导致形成大批低产井的问题,进而整体盘活低产区。

关键词：鱼骨刺水平井渗透率压降漏斗高庄区块

Identification and classification of promoters using the attention mechanism based on long short-term memory

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Frontiers of Computer Science 2022年第4期16卷 103-109页

作者： Qingwen Li lichao Zhang Lei xu Quan Zou Jin Wu Qingyuan Li Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of ChinaChengdu610054China State Key Laboratory of Brain and Cognitive Science Institute of BiophysicsChinese Academy of SciencesBeijing100101China Forestry and Fruit Tree Research Institute Wuhan Academy of Agricultural SciencesWuhan430075China School of Intelligent Manufacturing and Equipment Shenzhen Institute of Information TechnologyShenzhen518172China School of Electronic and Communication Engineering Shenzhen PolytechnicShenzhen518055China School of Management Shenzhen PolytechnicShenzhen518055China

A promoter is a short region of DNA that can bind RNA polymerase and initiate gene *** is usually located directly upstream of the transcription initiation *** promoters have been proven to be the main cause of many human diseases,especially diabetes,cancer or Huntington’s ***,the classification of promoters has become an interesting problem and has attracted the attention of many researchers in the field of *** studies have been conducted in order to solve this problem,but their performance still needs further *** this research,we segmented the DNA sequence in a k-mers manner,then trained the word vector model,inputted it into long short-term memory(LSTM)and used the attention mechanism to *** method can achieve 93.45%and 90.59%cross-validation accuracy in the two layers,*** results are better than others based on the same data set,and provided some ideas for accurately predicting *** addition,this research suggested that natural language processing can play a significant role in biological sequence prediction.

关键词： promoter bioinformatics natural language processing attention mechanism