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ImSpiRE: image feature-aided spatial resolution enhancement method

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Science China Life Sciences 2025年第1期 272-283页

作者： Yuwei Hua Yizhi Zhang Zhenming Guo Shan Bian yong Zhang State Key Laboratory of Cardiovascular Diseases and Medical Innovation Center Institute for Regenerative MedicineDepartment of NeurosurgeryShanghai East HospitalShanghai Key Laboratory of Signaling and Disease ResearchFrontier Science Center for Stem Cell ResearchSchool of Life Sciences and TechnologyTongji University

The resolution of most spatially resolved transcriptomic technologies usually cannot attain the single-cell level, limiting their applications in biological discoveries. Here, we introduce ImSpiRE, an image feature-aided spatial resolution enhancement method for in situ capturing spatial transcriptome. Taking the information stored in histological images, ImSpiRE solves an optimal transport problem to redistribute the expression profiles of spots to construct new transcriptional profiles with enhanced resolution, together with extending the gene expression profiles into unmeasured regions. Applications to multiple datasets confirm that ImSpiRE can enhance spatial resolution to the subspot level while contributing to the discovery of tissue domains, signaling communication patterns, and spatiotemporal characterization.

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基于轻量化卷积神经网络的桥梁斜拉索PE护套损伤识别方法

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土木与环境工程学报（中英文） 2025年第1期47卷 167-178页

作者：刘啸宇黄永徐峰李惠上海交通大学船舶海洋与建筑工程学院上海200240 哈尔滨工业大学土木工程学院哈尔滨150090

深度神经网络和计算机视觉技术近年来在结构健康监测中发挥了越来越重要的作用。利用无人机航拍采集的桥梁斜拉索损伤图像数据,研究基于深度学习技术的斜拉索PE护套损伤识别方法。为实现在较低运算能力设备上对大跨度桥梁斜拉索表面局... 详细信息

深度神经网络和计算机视觉技术近年来在结构健康监测中发挥了越来越重要的作用。利用无人机航拍采集的桥梁斜拉索损伤图像数据,研究基于深度学习技术的斜拉索PE护套损伤识别方法。为实现在较低运算能力设备上对大跨度桥梁斜拉索表面局部损伤的智能快速识别,解决传统深度卷积神经网络的运算效率相对较低、模型参数规模较大的问题,提出轻量化处理的区域推荐型卷积神经网络模型。介绍区域推荐网络与其轻量化改进方法的理论基础,分析轻量化模型处理的必要性,其能在保证识别精度的前提下降低模型训练与预测的设备性能需求,达到节约计算资源与时间的目的;通过数据增广等多手段解决损伤样本数据量不足的问题,设置对比试验,统计分析结果,验证了轻量化神经网络模型的优越性。结果表明,轻量化网络在牺牲少量识别准确度的前提下,能够在较大程度上实现对模型复杂度与计算量的改进,在工程应用中能有效拓展神经网络的实用性。

关键词：桥梁斜拉索智能损伤识别轻量化神经网络计算机视觉深度学习

Kernel selection with spectral perturbation stability of kernel matrix

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Science China(Information Sciences) 2014年第11期57卷 47-56页

作者： LIU yong liao ShiZhong School of Computer Science and Technology Tianjin University

Kernel selection is one of the key issues both in recent research and application of kernel *** is usually done by minimizing either an estimate of generalization error or some other related performance measure. Use of notions of stability to estimate the generalization error has attracted much attention in recent years. Unfortunately, the existing notions of stability, proposed to derive the theoretical generalization error bounds, are difficult to be used for kernel selection in practice. It is well known that the kernel matrix contains most of the information needed by kernel methods, and the eigenvalues play an important role in the kernel matrix. Therefore, we aim at introducing a new notion of stability, called the spectral perturbation stability,to study the kernel selection problem. This proposed stability quantifies the spectral perturbation of the kernel matrix with respect to the changes in the training set. We establish the connection between the spectral perturbation stability and the generalization error. By minimizing the derived generalization error bound, we propose a new kernel selection criterion that can guarantee good generalization properties. In our criterion,the perturbation of the eigenvalues of the kernel matrix is efficiently computed by solving the derivative of a newly defined generalized kernel matrix. Both theoretical analysis and experimental results demonstrate that our criterion is sound and effective.

关键词： kernel methods kernel selection stability spectral perturbation stability generalization error bound

The efficiency of postoperative liver failure and mortality risk scores after liver resection for perihilar cholangiocarcinoma

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Hepatobiliary Surgery and Nutrition 2022年第4期11卷 643-644页

作者： Qingbo feng Wenwei liao Jiaxin Li yong Zeng Department of Liver Surgery&Liver Transplantation State Key Laboratory of Biotherapy and Cancer CenterWest China HospitalSichuan University and Collaborative Innovation Center of BiotherapyChengduChina

With great interest,we read the literature by Noji et ***“Validation study of postoperative liver failure and mortality risk scores after liver resection for perihilar cholangiocarcinoma”(1),which was published in the latest issue of Hepatobiliary Surgery *** authors have reached an important conclusion that postoperative mortality risk score(POMRS)and post-hepatectomy liver failure score(PHLFS)proposed by the Academic Medical Center(AMC)and Memorial Sloan Kettering Cancer Center(MSKCC)require optimization before use in clinical ***,after a careful reading of this study,we would like to address several fundamental flaws related to this article.

关键词： postoperative mortality Surgery

Comprehensive modeling of ignition and combustion of multiscale aluminum particles under various pressure conditions

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Chinese Journal of Aeronautics 2024年第11期37卷 188-202页

作者： Zhenkun HU Ying feng Wei DONG yong TANG Jia LI Lijuan liao Majie ZHAO Baolu SHI School of Aerospace Engineering Beijing Institute of TechnologyBeijing 100081China Key Laboratory for Mechanics in Fluid Solid Coupling Systems Institute of MechanicsChinese Academy of SciencesBeijing 100190China Chongqing Innovation Center Beijing Institute of TechnologyChongqing 404100China

The ignition and combustion of aluminum particles are crucial to achieve optimal energy release in propulsion and power systems within a limited residence *** study seeks to develop theoretical ignition and combustion models for aluminum particles ranging from 10 nm to 1000μm under wide pressure ranges of normal to beyond 10 ***,a parametric analysis illustrates that the convective heat transfer and heterogeneous surface reaction are strongly influenced by pressure,which directly affects the ignition ***,the ignition delay time can be correlated with pressure through the p^(b)relationship,with b increasing from-1 to-0.1 as the system transitions from the free molecular regime to the continuum ***,the circuit comparison analysis method was used to interpret an empirical formula capable of predicting the ignition delay time of aluminum particles over a wide range of pressures in N_(2),O_(2),H_(2)O,and CO_(2)***,an analysis of experimental data indicates that the exponents of pressure dependence in the combustion time of large micron-sized particles and nanoparticles are-0.15 and-0.65,***,the dominant combustion mechanism of multiscale aluminum particles was quantitatively demonstrated through the Damköhler number(Da)*** have shown that aluminum combustion is mainly controlled by diffusion as Da>10,by chemical kinetics when Da≤0.1,and codetermined by both diffusion and chemical kinetics when 0.1

关键词： Multiscale aluminum particles Ignition delay time Combustion mechanism Combustion time Pressure

A NOTE ON STABILITY OF THE SPLIT-STEP BACKWARD EULER METHOD FOR LINEAR STOCHASTIC DELAY INTEGRO-DIFFERENTIAL EQUATIONS

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Journal of Systems Science & Complexity 2012年第5期25卷 873-879页

作者： feng JIANG Yi SHEN Xiaoxin liao Department of Control Science and Engineering Huazhong University of Science and Technology School of Statistics and Mathematics Zhongnan University of Economics and Law Department of Control Science and Engineering the Key Laboratory of Ministry of Eduction for Image Processing and Intelligent ControlHuazhong University of Science and Technology

In the literature （Tan and Wang, 2010）, Tan and Wang investigated the convergence of the split-step backward Euler （SSBE） method for linear stochastic delay integro-differential equations （SDIDEs） and proved the mean-square stability of SSBE method under some condition. Unfortu- nately, the main result of stability derived by the condition is somewhat restrictive to be applied for practical application. This paper improves the corresponding results. The authors not only prove the mean-square stability of the numerical method but also prove the general mean-square stability of the numerical method. Furthermore, an example is given to illustrate the theory.

关键词： General mean-square stability mean-square stability split-step backward Euler method stochastic delay integro-differential equations.

Viscosity and structure relationship with equimolar substitution of CaO with MgO in the CaO–MgO–Al_(2)O_(3)–SiO_(2)slag melts

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 70-79页

作者： yong Hou Shuo Zhang Jie Dang Jia Guo Hanghang Zhou Xuewei Lü College of Materials Science and Engineering Chongqing UniversityChongqing 400044China Chongqing Key Laboratory of Vanadium-Titanium Metallurgy and New Materials Chongqing UniversityChongqing 400044China

Currently,the Al_(2)O_(3)content in the high-alumina slag systems within blast furnaces is generally limited to 16wt%–18.5wt%,making it challenging to overcome this *** most studies that concentrated on managing the MgO/Al_(2)O_(3)ratio or basicity,this paper explored the effect of equimolar substitution of MgO for CaO on the viscosity and structure of a high-alumina CaO-MgO-Al_(2)O_(3)-SiO_(2)slag system,providing theoretical guidance and data to facilitate the application of high-alumina *** results revealed that the viscosity first decreased and then increased with higher MgO substitution,reaching a minimum at 15mol%MgO *** transform infrared spectroscopy(FTIR)results found that the depths of the troughs representing[SiO_(4)]tetrahedra,[AlO_(4)]tetrahedra,and Si-O-Al bending became progressively deeper with increased MgO *** of the Raman spectra showed that the average number of bridging oxygens per Si atom and the X_(Q^(3))/X_(Q^(2))(X_(Q^(i))is the molar fraction of Q^(i) unit,and i is the number of bridging oxygens in a[SiO_(4)]tetrahedral unit)ratio increased from 2.30 and 1.02 to 2.52 and 2.14,respectively,indicating a progressive polymerization of the silicate structure.X-ray photoelectron spectroscopy(XPS)results highlighted that non-bridging oxygen content decreased from 77.97mol% to 63.41mol% with increasing MgO concentration,whereas bridging oxygen and free oxygen contents *** analysis demonstrated a gradual increase in the polymerization degree of the tetrahedral structure with the increase in MgO ***,bond strength is another important factor affecting the slag *** occurrence of a viscosity minimum can be attributed to the complex evolution of bond strengths of non-bridging oxygens generated during depolymerization of the[SiO_(4)]and[AlO_(4)]tetrahedral structures by CaO and MgO.

关键词： aluminosilicate viscosity structure spectroscopy

A New Traversable Wormhole Solution in Vacuum Brans-Dicke Theory

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Chinese Physics Letters 1999年第6期16卷 394-396页

作者： HE feng LIU liao Department of Physics Xiangtan Teachersf CollegeXiangtan 411100 Department of Physics Beijing Normal UniversityBeijing 100875

A new set of exact solutions in vacuum Brans-Dicke theory is obtained,which is a two-way traversable wormhole for the coupling parameterω(ω<-2).This new set of exact solutions satisfies not only the general constraints on the shape function b(R)and the redshift functionφ(R)given by Morris and Thorne[***.56(1988)395],but also the constraints on them from a trip through *** also follows that the scalar field φ plays a role of exotic mat ter violating the weak energy condition.

关键词： Brans Dicke constraints

Bubbles Created from Vacuum Fluctuation

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Chinese Physics Letters 2001年第8期18卷 1007-1008页

作者： LIU liao HE feng Department of Physics Beijing Normal UniversityBeijing 100875 Department of Physics Xiangtan Normal CollegeXiangtan 411201

The authors show that the bubbles S^(2) × S^(2) can be created from vacuum fluctuation in the background de Sitter universes of k=0,1,so the space-time foam-like structure might really be constructed from bubbles of S2 x S2 in the very early inflating phase of our ***,whether such foam-like structure persisted during the later evolution of the universe is a problem unsolved at present.

关键词： universe evolution Create