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Frontiers of Environmental Science & Engineering 2016年第2期10卷 327-335页

作者： liangliang wei Kun WANG Xiangjuan KONG Guangyi LIU Shuang CUI Qingliang ZHAO Fuyi CUI Key Laboratory of Songliao Aquatic Environment (Ministry of Education) Jilin Jianzhu University Changchun 130118 China School of Mu-nicipal & Environmental Engineering Harbin Institute of Technology Harbin 150090 China Center of Science & Technology of Construction of the Ministry of Housing and Urban Rural Development of E R. China Beijing 100835 China Procter & Gamble Company Guangzhou 510620 China

一个新奇方法被用于共同恢复从为液体化肥和动物的除去的污水污泥的蛋白质和腐殖的酸喂。在污水污泥的蛋白质首先用 ultrasonication 和酸降水的过程被提取，然后腐殖的酸经由膜过滤被恢复。抽取效率是 125.9 mg 腐殖的酸 ?????????????... 详细信息

一个新奇方法被用于共同恢复从为液体化肥和动物的除去的污水污泥的蛋白质和腐殖的酸喂。在污水污泥的蛋白质首先用 ultrasonication 和酸降水的过程被提取，然后腐殖的酸经由膜过滤被恢复。抽取效率是 125.9 mg 腐殖的酸 ???????????????????????? 卓吗？

关键词：天然蛋白质脱水污泥超声应用腐殖酸可回收酸沉淀膜过滤提取效率

Coupled autotransformer and magneticcontrol soft-start method for super-largecapacity high-voltage motors

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High Voltage 2020年第1期5卷 38-45页

作者： Jiaxin Yuan Chuansheng Wang Shan Yin liangliang wei Kazuhiro Muramatsu Baichao Chen School of Electrical Engineering and Automation Wuhan UniversityWuhanPeople's Republic of China Shenzhen Institute of Wuhan University ShenzhenPeople's Republic of China China Energy Engineering Group Jiangsu Power Design Institute Company NanjingPeople's Republic of China Department of Electrical Engineering Kyoto UniversityKyotoJapan Department of Electrical and Electronic Engineering Saga UniversitySagaJapan

The large current generated by a direct start of the super-large-capacity high-voltage induction motor would have a huge impact on the power grid as well as the motor itself.Traditional soft starters have the shortcomings of discontinuous adjustment,voltage sags,sudden torque mutation,secondary current impact and high cost.To resolve this issue,the authors propose a novel coupled autotransformer and magnetic-control(CATMC)soft-start method.The structure of the new CATMC soft starter combines the functions of the autotransformer and magnetic control reactor via an innovative electric and magnetic circuit design.In this study,the authors analyse the magnetic circuit structure and working principles of the CATMC soft starter.Then,to validate its principle and performance,the authors conduct a simulation study using ANSYS software and design and test an 18 MW/10 kV CATMC soft starter prototype.The simulation results demonstrate that the CATMC soft starter effectively avoids secondary current impact and constrains the motor starting current to<2.5 times the rated current.The public connection point bus voltage also meets the voltage sag requirement of the IEEE standard and reduces the impact on the power grid.

关键词： shortcomings starting combine

A review of ARGs in WWTPs:Sources,stressors and elimination

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Chinese Chemical Letters 2020年第10期31卷 2603-2613页

作者： Kena Qin liangliang wei Jianju Li Bo Lai Fengyi Zhu Hang Yu Qingliang Zhao Kun Wang State Key Laboratory of Urban Water Resources and Environment(SKLUWRE) School of EnvironmentHarbin Institute of TechnologyHarbin 150090China State Key Laboratory of Hydraulics and Mountain River Engineering College of Architecture and EnvironmentSichuan UniversityChengdu 610065China

Antibiotic re sistance genes(ARGs)in aquatic enviro nments,which seriously endanger human health and ecological safety,have become a worldwide concern due to their easy diffusion and proliferation.Wastewater treatment plants(WWTPs),which receive resistant bacteria and ARGs from a wide variety of sources(i.e.,livestock farms,hospitals,antibiotic manufactures,and households),are regarded as important emission sources of aquatic ARGs.This review presents a quantitative profile of the majority sources of ARGs in the influent of WWTPs and discusses the potential factors that affect the concentration distribution of ARGs.Specifically,a noteworthy existence of ARGs,which ranged from 1 E+05 to 1 E+11 copies/mL,was detected in livestock breeding wastewater,and household wastewater(caused by the unlimited utilization of antibiotics)was determined to be the predominant contributor of ARGs in WWTPs.We summarized the selective pressure on ARGs and determined the positive correlation of the concentration of ARGs and the existence of many containments,including antibiotics,heavy metals(Zn and Cu were frequently reported),quaternary ammonium compounds,etc.In the last section,physical,chemical,and biological treatments for the removal of ARGs and their effluent in WWTPs are discussed and prospective future studies are summarized.

关键词： Antibiotics Antibiotics resistance genes Sources Stressors Artificial treatments

Extracellular polymeric substances-antibiotics interaction in activated sludge:A review

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Environmental Science and Ecotechnology 2023年第1期13卷 23-36页

作者： weixin Zhao Jia You Shilei Yin Haizhou Yang Shufei He Likui Feng Jianju Li Qingliang Zhao liangliang wei State Key Laboratory of UrbanWater Resources and Environment(SKLUWRE) School of EnvironmentHarbin Institute of TechnologyHarbin150090China

Antibiotics,the most frequently prescribed drugs,have been widely applied to prevent or cure human and veterinary diseases and have undoubtedly led to massive releases into sewer networks and wastewater treatment systems,a hotspot where the occurrence and transformation of antibiotic resistance take place.Extracellular polymeric substances(EPS),biopolymers secreted via microbial activity,play an important role in cell adhesion,nutrient retention,and toxicity resistance.However,the potential roles of sludge EPS related to the resistance and removal of antibiotics are still unclear.This work summarizes the composition and physicochemical characteristics of state-of-the-art microbial EPS,highlights the critical role of EPS in antibiotics removal,evaluates their defense performances under different antibiotics exposures,and analyzes the typical factors that could affect the sorption and biotransformation behavior of antibiotics.Next,interactions between microbial EPS and antibiotic resistance genes are analyzed.Future perspectives,especially the engineering application of microbial EPS for antibiotics toxicity detection and defense,are also emphatically stressed.

关键词： Extracellular polymeric substances Antibiotics Antibiotic resistance genes Sorption Biotransformation Resistance

Assessment of solar-assisted electrooxidation of bisphenol AF and bisphenol A on boron-doped diamond electrodes

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Environmental Science and Ecotechnology 2020年第3期3卷 23-31页

作者： Jing Ding Lingjun Bu Bingxin Cui Guanshu Zhao Qingwei Gao liangliang wei Qingliang Zhao Dionysios D.Dionysiou State Key Laboratory of Urban Water Resources and Environment(SKLUWRE) School of EnvironmentHarbin Institute of TechnologyHarbin150090China Department of Water Engineering and Science College of Civil EngineeringHunan UniversityChangsha410082China Environmental Engineering and Science Program Department of Chemical and Environmental EngineeringUniversity of CincinnatiCincinnatiOH45221USA

Bisphenol(BP)analogues in wastewater effluent and groundwater pose a potential threat to human health due to their ability to disrupt steroidogenesis.A new solar-assisted electrochemical process(SECP)was developed and evaluated for the degradation of BP analogues.The effects of quenchers,current density,initial pH,supporting electrolyte,and aqueous matrix on the removal kinetics of bisphenol AF(BPAF)and bisphenol A(BPA)were investigated.The kinetic constants of BPAF,BPA,and bisphenol S(BPS)in the SECP with irradiation intensity of 500 mW cm^(-2) were 0.017±0.002 min^(-1),0.022±0.002 min^(-1),and 0.012±0.001 min^(-1),respectively.The changes in the degradation rates of BPAF,BPA,and BPS in the presence of quenchers indicated the relative contribution of hydroxyl radical(·OH)oxidation,anodic electrolysis,and singlet(^(1)O_(2))oxygenation in the degradation of BPs in the SECP.The enhanced rate of generation of ·OH and ^(1)O_(2) was observed in the SECP compared with those in the conventional electrochemical system.The identification of the transformation products(TPs)of BPAF demonstrated that hydroxylation,ring cleavage,b-scission,and defluorination were the major processes during the oxidation in the SECP.The conversion to fluoride ions(76%)and mineralization of total organic carbon(72%)in the SECP indicated further degradation of TPs.The results from this study improved our understanding of the degradation of BP analogues in the electrooxidation irradiated by solar light and help to establish the application potential of the SECP for the effective degradation of emerging contaminants in wastewater.

关键词： Electrochemical process Solar Radicals Bisphenol AF Wastewater treatment

Trihalomethane formation potential of organic fractions in secondary effluent

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Journal of Environmental Sciences 2008年第5期20卷 520-527页

作者： XUE Shuang ZHAO Qingliang wei liangliang JIA Ting School of Municipal and Environmental Engineering Harbin Institute of Technology Harbin 150090 China State Key Laboratory of Urban Water Resources and Environment （SKLUWRE） Harbin Institute of Technology Harbin 150090 China School of Environmental Science Liaoning University Shengyang 110036 China

Organic matter is known to be the precursor of numerous chlorination by-products. Organic matter in the secondary effluent from the Wenchang Wastewater Treatment Plant （Harbin, China） was physically separated into the following fractions： particulate organic carbon （1.2-0.45 μm）, colloidal organic carbon （0.45-0.1 μm）, fine colloidal organic carbon （0.1-0.025 μm）, and dissolved organic carbon （DOC）（〈 0.025 μm）. Moreover, 〈 0.45 μm fraction was chemically separated into hydrophobic acid （HPO-A）, hydrophobic neutral （HPO-N）, transphilic acid （TPI-A）, transphilic neutral （TPI-N）, and hydrophllic fraction （HPI）. The chlorine reactivity of these organic fractions obtained from both size and XAD fractionations were evaluated. The structural and chemical compositions of the HPO-A, HPO-N, TPI-A, and TPI-N isolates were characterized using elemental analysis （C, H, O, and N）, Fourier transform infrared spectroscopy （FT-IR）, and proton nuclear magnetic resonance spectroscopy （1H-NMR）. Results showed that DOC was dominant in terms of total concentration and trihalomethane formation potential （THMFP）, and there was no statistical difference in both specific THMFP （STHMFP） and specific ultraviolet light absorbance among the 0.45, 0.1, and 0.025 ixm filtrates. HPO-A had the highest STHMFP compared to other chemical fractions. HPO-A, HPO-N, TPI-A, and TPI-N contained 3.02%-3.52% of nitrogen. The molar ratio of H/C increased in the order of HPO-A 〈 HPO-N 〈 TPI-A 〈 TPI-N. The O/C ratio was relatively high for TPI-N as compared to those for the other fractions. ^1H-NMR analysis of the four fractions indicated that the relative content of aromatic protons in HPO-A was significantly higher than those in the others. The ratio of aliphatic to aromatic protons increased in the order of HPO-A 〈 HPO-N 〈 TPI-A 〈 TPI-N. FT-IR analysis of the four fractions showed that HPO-A had greater aromatic C=C content whereas HPO-N, TPI-A, and TPI-N had greater aliphatic C-H content. TPI-N contained more oxygen-containing functional groups than the o

关键词： organic carbon trihalomethane formation potential （THMFP） chlorination FT-IR ^1H-NMR

我国涉农高校环境类专业课程设置特征及未来人才培养体系升级建议

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高教学刊 2024年第10期10卷 31-34页

作者：魏亮亮姜珺秋王广智张国栋丁晶张军赵庆良哈尔滨工业大学环境学院哈尔滨150090 青岛农业大学资源与环境学院山东青岛266109

在乡村振兴战略全面推进、农村人居环境治理得到广泛关注的时代背景下,环境类专业如何结合当前国家建设需求进一步完善适合知农爱农新型环保人才培养的课程体系,是当前环境类专业发展改革的一个重要方向。基于我国农业特色高校和环保强... 详细信息

在乡村振兴战略全面推进、农村人居环境治理得到广泛关注的时代背景下,环境类专业如何结合当前国家建设需求进一步完善适合知农爱农新型环保人才培养的课程体系,是当前环境类专业发展改革的一个重要方向。基于我国农业特色高校和环保强校涉农课程设置的前期调研,结合当前我国乡村振兴战略科技人才需求,该文重点梳理当前涉农课程的类别及课程建设特征,在此基础上剖析环境工程、环境科学、环境生态工程和农业资源与环境等专业的涉农课程设置特色,并提出适合未来我国生态环境领域知农爱农型人才培养的课程体系建设建议。相关研究结果有助于推动新时代知农爱农新型环保人才培养体系的升级与重构。

关键词：乡村振兴环境类专业人才培养知农爱农课程体系

颅内动脉瘤模型大鼠端粒长度与端粒结合蛋白基因表达变化

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检验医学与临床 2024年第12期21卷 1785-1789页

作者：唐政史新宇孔庆梅李清振韦亮亮付浩黄生炫宝鸡高新医院神经外科陕西宝鸡721013 宝鸡高新医院急诊科陕西宝鸡721013 福建医科大学附属三明市第一医院神经外科福建三明365000

目的探讨颅内动脉瘤(IA)大鼠外周血端粒长度及其结合蛋白基因表达变化,初步探讨IA的潜在机制。方法将24只SD雌性大鼠随机等分为两组,即对照组和IA模型组(以下简称模型组)。模型组结扎左侧颈总动脉、结扎双侧肾动脉后支、切除双侧卵巢,... 详细信息

目的探讨颅内动脉瘤(IA)大鼠外周血端粒长度及其结合蛋白基因表达变化,初步探讨IA的潜在机制。方法将24只SD雌性大鼠随机等分为两组,即对照组和IA模型组(以下简称模型组)。模型组结扎左侧颈总动脉、结扎双侧肾动脉后支、切除双侧卵巢,并于造模后1周喂同时含8%氯化钠和3%L-甲硫氨酸的饲料。对照组则仅暴露左侧颈总动脉和双肾20 min后缝合皮肤,喂常规饲料。两组大鼠分别于造模前和造模后6个月时进行眶下静脉丛取血并提取外周血基因组DNA,检测相对端粒长度。造模后6个月时处死前测量血压及检测血清中雌二醇、同型半胱氨酸(Hcy)水平,提取外周血总RNA并检测6种端粒结合蛋白[端粒重复序列结合因子1(TRF1)、端粒重复序列结合因子2(TRF2)、端粒保护蛋白1(POT1)、肾上腺皮质增生蛋白同源异构体(TPP1)、TRF1相互作用核蛋白2(TIN2)、阻滞活化蛋白1(RAP1)]基因表达水平的变化。处死后通过血管铸型观察IA形成情况。结果造模后6个月时,模型组大鼠收缩压和血清Hcy水平均高于对照组(P0.05);造模后6个月时,模型组大鼠端粒长度明显短于对照组,差异有统计学意义(P0.05)。结论IA模型大鼠造模后6个月时,外周血端粒长度明显缩短,端粒结合蛋白TRF2和TPP1基因表达水平上调,这可能与IA的病因机制相关。

关键词：端粒颅内动脉瘤端粒结合蛋白大鼠雌二醇同型半胱氨酸

Processing of a low-cost γ-γ' NiPtAl coating with improved oxidation resistance

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Rare Metals 2024年第6期43卷 2832-2841页

作者： Yan Jiang Liang-Liang wei Jian He Hong-Bo Guo School of Materials Science and Engineering Beihang University Key Laboratory of High-Temperature Structural Materials and Protective Coatings Ministry of Industry and Information TechnologyBeihang University

A novel γ-γ'（Ni solid solution—Ni3Al） NiPtAl coating was produced on advanced single-crystal（SC）superalloy N5 by electroplating of a thin Pt coating with～3 μm in thickness followed by heat treatment at 1000 ℃ in vacuum.For comparison,a traditional γ-γ'NiPtAl coating was also produced by electroplating of a thick Pt coating with ～ 6 μm in thickness followed by heat treatment at 1100 ℃ in vacuum.The novel coating has a mass gain of～ 0.5 mg·cm-2after 100 h 1-h cyclic oxidation at 1150℃,showing better oxidation resistance than the traditional coating.An oxide scale mostly consisting of α-Al2O3grew on the novel coating because the element Cr from the SC alloy substrate contributes to the formation of α-Al2O3.Pt content in the novel coating has significant effect on the oxidation resistance.The optimized Pt content in the coating is about 16 at%,which is helpful to reduce the diffusion of harmful elements from the substrate into the coating but also to reduce the cost of the coating.

关键词： γ–γ′ NiPtAl coating Platinum Oxidation Al 2 O 3 Superalloy

Hydralazine represses Fpn ubiquitination to rescue injured neurons via competitive binding to UBA52

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Journal of Pharmaceutical Analysis 2024年第1期14卷 86-99页

作者： Shengyou Li Xue Gao Yi Zheng Yujie Yang Jianbo Gao Dan Geng Lingli Guo Teng Ma Yiming Hao Bin wei liangliang Huang Yitao wei Bing Xia Zhuojing Luo Jinghui Huang Department of Orthopedics Xijing HospitalFourth Military Medical UniversityXi'an710032China

A major impedance to neuronal regeneration after peripheral nerve injury (PNI) is the activation of various programmed cell death mechanisms in the dorsal root ganglion. Ferroptosis is a form of programmed cell death distinguished by imbalance in iron and thiol metabolism, leading to lethal lipid peroxidation. However, the molecular mechanisms of ferroptosis in the context of PNI and nerve regeneration remain unclear. Ferroportin (Fpn), the only known mammalian nonheme iron export protein, plays a pivotal part in inhibiting ferroptosis by maintaining intracellular iron homeostasis. Here, we explored in vitro and in vivo the involvement of Fpn in neuronal ferroptosis. We first delineated that reactive oxygen species at the injury site induces neuronal ferroptosis by increasing intracellular iron via accelerated UBA52-driven ubiquitination and degradation of Fpn, and stimulation of lipid peroxidation. Early administration of the potent arterial vasodilator, hydralazine (HYD), decreases the ubiquitination of Fpn after PNI by binding to UBA52, leading to suppression of neuronal cell death and significant acceleration of axon regeneration and motor function recovery. HYD targeting of ferroptosis is a promising strategy for clinical management of PNI.

关键词： Ferroptosis UBA52 Ferroportin Ubiquitination Hydralazine Peripheral nerve injury