检索结果-南通市图书馆

知识的地方性——以博爱理的生物学研究转向为例

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

科学技术哲学研究 2024年第1期41卷 88-94页

作者：梁佳媛北京大学医学人文学院北京100191

文章考察了燕京大学生物学系美籍教员博爱理在20世纪30年代做出的学术研究转向。作为一名在美国接受正规学术训练的研究人员,博爱理早期追随摩尔根、康克林等学者从事细胞胚胎学研究;而在1923年来华后,她逐步舍弃当时被认为较具发展前... 详细信息

文章考察了燕京大学生物学系美籍教员博爱理在20世纪30年代做出的学术研究转向。作为一名在美国接受正规学术训练的研究人员,博爱理早期追随摩尔根、康克林等学者从事细胞胚胎学研究;而在1923年来华后,她逐步舍弃当时被认为较具发展前景的实验性学科门类,转而从事传统意义上的描述性生物学科分支。文章认为,这种具有明显跨度的研究转向,反映了20世纪前半叶中国特定的自然与社会-文化情境对生物学科分支的适应性筛选机制,以及生物学知识的“地方性生成”特性。借此论点,文章进而提出相对主义视角下的“学科建制”概念,认为生物学分支学科的建制过程以地方性知识的自主规模性生成为其本质特征。

关键词：学科建制知识生成系统生物学

16.48% Efficient solution-processed CIGS solar cells with crystal growth and defects engineering enabled by Ag doping strategy

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2025年第1期100卷 59-65页

作者： Mengyu Xu Shaocong Yan Ting liang jia jia Shengjie yuan Dongxing Kou Zhengji Zhou Wenhui Zhou Yafang Qi Yuena Meng Litao Han Sixin Wu Key Laboratory for Special Functional Materials of MOE National & Local Joint Engineering Research Centre for High-efficiency Display and Lighting Technology School of Nanoscience and Materials Engineering Henan University

Solution-processed Cu（In,Ga）Se2（CIGS） solar cells suffer from serious carrier recombination and power conversion efficiency（PCE） loss because of the poor film properties and easy formation of ***, we propose Ag&Se co-selenization strategy to enhance the crystallization and passivate harmful defects of the CIGS films. The formation of Ag-Se phase during the selenization process enables the formation of large grains and suppresses the deep level defects. It is found that Ag doping can enlarge the depletion region width, lower the Urbach energy and prolong the carrier lifetime. As a result, a champion solution-processed CIGS solar cell presents a high efficiency of 16.48% with the highly improved opencircuit voltage（VOC） of 662 m V and fill factor（FF） of 75.8%. This work provides an efficient strategy to prepare high quality solution-processed CIGS films for high-performance CIGS solar cells.

关键词： CIGS solar cells Solution-processed method Ag doping Crystal growth Defects engineering

The dopaminergic system and Alzheimer's disease

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第9期20卷 2495-2512页

作者： Yuhan Zhang yuan liang Yixue Gu International Medical College Chongqing Medical UniversityChongqingChina College of Pharmacy Chongqing Medical UniversityChongqingChina Department of Neurology The First Affiliated Hospital of Chongqing Medical UniversityChongqing Key Laboratory of NeurologyChongqingChina

Alzheimer's disease is a common neurodegenerative disorder in older *** its prevalence,its pathogenesis remains unclea *** addition to the most widely accepted causes,which in clude excessive amyloid-beta aggregation,tau hyperphosphorylation,and deficiency of the neurotransmitter acetylcholine,numerous studies have shown that the dopaminergic system is also closely associated with the occurrence and development of this *** is a crucial catecholaminergic neurotransmitter in the human ***-associated treatments,such as drugs that target dopamine receptor D and dopamine analogs,can improve cognitive function and alleviate psychiatric symptoms as well as ameliorate other clinical *** r,therapeutics targeting the dopaminergic system are associated with various adverse reactions,such as addiction and exacerbation of cognitive *** review summarizes the role of the dopaminergic system in the pathology of Alzheimer's disease,focusing on currently available dopamine-based therapies for this disorder and the common side effects associated with dopamine-related *** aim of this review is to provide insights into the potential connections between the dopaminergic system and Alzheimer's disease,thus helping to clarify the mechanisms underlying the condition and exploring more effective therapeutic options.

关键词： adverse drug reaction Alzheimer's disease catecholamine dopamine receptor dopamine receptor heterodimers dopaminergic system neurodegenerative disease neurotransmitter signaling pathways traditional Chinese medicine treatment

在线全文

学校读者我要写书评

暂无评论

房屋建筑混凝土结构问题及加固方法

建筑技术开发 2018年第22期45卷 44-45页

作者：梁家远沂水县村镇建设管理处山东临沂276400

钢筋混凝土结构中,混凝土提出多种加固方法,针对目前加固技术中存在的问题进行分析,可为广大建筑工作者提供参考。

关键词：房屋建筑混凝土裂缝结构加固

在线全文

学校读者我要写书评

暂无评论

我国首部近代生理学译著《体用十章》底本考

内蒙古师范大学学报（自然科学汉文版） 2018年第5期47卷 436-439页

作者：梁佳媛中国科学院自然科学史研究所北京100190 中国科学院大学北京100049

1884年,孔庆高翻译出版的《体用十章》,是迄今所知首部传入我国的近代生理学著作.一般认为该书译自赫胥黎(Huxley)、尤曼(Youman)合著的《生理学手册》Manual Physiology,通过具体的比对,发现其底本更可能是赫胥黎《基础生理学教程》Les... 详细信息

1884年,孔庆高翻译出版的《体用十章》,是迄今所知首部传入我国的近代生理学著作.一般认为该书译自赫胥黎(Huxley)、尤曼(Youman)合著的《生理学手册》Manual Physiology,通过具体的比对,发现其底本更可能是赫胥黎《基础生理学教程》Lessons in Elementary Physiology的第三版(1872年).底本在西方生理学史上亦有卓著地位.

关键词：《体用十章》近代生理学赫胥黎

《艺文类聚》中“药香草部”的主要内容、文献来源与传播情况

在线全文

学校读者我要写书评

暂无评论

中医文献杂志 2016年第5期34卷 1-6页

作者：韩毅梁佳媛中国科学院自然科学史研究所北京100190

唐初欧阳询等敕撰的《艺文类聚》是我国现存最早的一部官修类书。书中的"药香草部",是我国自《神农本草经》问世以来,首次在非医学著作中以"随类相从"体例编辑的大型药物学论著,共收载药物43种,其中包括常用药物11种,香草药物28种,菜蔬... 详细信息

唐初欧阳询等敕撰的《艺文类聚》是我国现存最早的一部官修类书。书中的"药香草部",是我国自《神农本草经》问世以来,首次在非医学著作中以"随类相从"体例编辑的大型药物学论著,共收载药物43种,其中包括常用药物11种,香草药物28种,菜蔬药物4种,引用文献约517种,不仅详细地介绍药物的名称、来源、分布、采摘时间、入药部位、炮制和主治病症,而且还收载了大量的医学病案、医学人物和医学典故等,在中国药物史上占有重要的地位。

关键词：艺文类聚药香草部类书医学文献

在线全文

学校读者我要写书评

暂无评论

串联式磨盘螺杆挤出机混合过程的研究

渤海大学学报（自然科学版） 2013年第4期34卷 407-411,424页

作者：庄园园李翱毕超梁家源北京化工大学机电工程学院北京100029

采用网格重叠技术(MST)生成串联式磨盘螺杆挤出机混炼段的有限元网格,对物料在混炼段流场中的动态混合过程进行了模拟,研究了物料粒子的运动轨迹和混合过程;采用流体动力学分析软件POLYFLOW模拟混炼过程,选取停留时间和最大剪切应力作... 详细信息

采用网格重叠技术(MST)生成串联式磨盘螺杆挤出机混炼段的有限元网格,对物料在混炼段流场中的动态混合过程进行了模拟,研究了物料粒子的运动轨迹和混合过程;采用流体动力学分析软件POLYFLOW模拟混炼过程,选取停留时间和最大剪切应力作为量化指标,分析和评价了该挤出机混炼段的物料混合性能.研究发现物料在串联式磨盘螺杆挤出机混炼段的停留时间较长,分布范围较广,有利于物料的分散混合和分布混合,得到性能稳定的产品.

关键词：串联式磨盘螺杆挤出机混合性能停留时间最大剪切应力

Endogenous/exogenous dual stimulation“ROS engineering”amplification combined with autophagy-augmented for efficient ferroptosis therapy

在线全文

学校读者我要写书评

暂无评论

Nano Research 2025年第1期18卷 597-606页

作者： Pengye Du Pengpeng Lei yuan liang Ran An Yi Wei Shuyu Liu jianhao Zheng Hongjie Zhang State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China School of Applied Chemistry and Engineering University of Science and Technology of ChinaHefei 230026China Department of Chemistry Tsinghua UniversityBeijing 100084China

“Reactive oxygen species(ROS)engineering”is one of the most promising anti-tumor treatments developed in recent *** explosion of ROS will cause oxidative stress,thereby inducing tumor cell ***,ROS accumulation in tumor cells is eliminated by endogenous cellular self-regulation *** this work,a kind of endogenous/exogenous dual stimulation nanoagent noted as UMZC is *** reaction occurs between NH_(2)-MIL-88B(Fe)contained in UMZC and the overexpression of endogenous H_(2)O_(2)to generate ROS,amplified by endogenous H_(2)S of colon tumor *** addition,NH_(2)-MIL-88B(Fe)also functions to deplete glutathione(GSH)for stopping it from consuming *** nanoparticles at the core of UMZC convert near-infrared into visible light,which excites zinc phthalocyanine to initiate the photochemical reaction that generates more ROS,thus alleviating the lack of tissue penetration depth for visible *** agonist chitosan oligosaccharides induce enhancement of cellular autophagy for disrupting cellular metabolic stress and the resistance to oxidative stress of tumor cells,allowing“ROS engineering”to fully exert anti-tumor *** of ROS generation,GSH depletion,and induced cellular autophagy caused by nanoagents have promoting effects on the occurrence of ***,the nanoagents show the ability to effectively treat colon tumors.

关键词： reactive oxygen species(ROS)engineering upconversion nanoparticles cellular autophagy ferroptosis tumor therapy

“Zero‑Strain” NiNb_(2)O_(6) Fibers for All‑Climate Lithium Storage

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano-Micro Letters 2025年第1期17卷 348-360页

作者： Yan Zhao Qiang yuan Liting Yang Guisheng liang Yifeng Cheng Limin Wu Chunfu Lin Renchao Che College of Physics Donghua UniversityShanghai 201620People’s Republic of China School of Materials Science and Engineering Institute of Materials for Energy and EnvironmentQingdao UniversityQingdao 266071People’s Republic of China Laboratory of Advanced Materials Shanghai Key Laboratory of Molecular Catalysis and Innovative MaterialsAcademy for Engineering&TechnologyFudan UniversityShanghai 200438People’s Republic of China Zhejiang Laboratory Hangzhou 311100People’s Republic of China Inner Mongolia University Hohhot 010021People’s Republic of China

Niobates are promising all-climate Li^(+)-storage anode material due to their fast charge transport,large specific capacities,and resistance to electrolyte ***,their moderate unit-cellvolume expansion(generally 5%–10%)during Li^(+)storage causes unsatisfactory long-term ***,“zero-strain”NiNb_(2)O_(6) fibers are explored as a new anode material with comprehensively good electrochemical *** Li^(+)storage,the expansion of electrochemical inactive NiO_(6) octahedra almost fully offsets the shrinkage of active NbO_(6) octahedra through reversible O *** superior volume-accommodation capability of the NiO_(6) layers guarantees the“zero-strain”behavior of NiNb_(2)O_(6) in a broad temperature range(0.53%//0.51%//0.74%at 25//−10//60℃),leading to the excellent cyclability of the NiNb_(2)O_(6) fibers(92.8%//99.2%//91.1%capacity retention after 1000//2000//1000 cycles at 10C and 25//−10//60℃).This NiNb_(2)O_(6) material further exhibits a large reversible capacity(300//184//318 mAh g−1 at 0.1C and 25//−10//60℃)and outstanding rate performance(10 to 0.5C capacity percentage of 64.3%//50.0%//65.4%at 25//−10//60℃).Therefore,the NiNb_(2)O_(6) fibers are especially suitable for large-capacity,fast-charging,long-life,and all-climate lithium-ion batteries.

关键词： NiNb_(2)O_(6)porous fiber “Zero-strain”mechanism Electrochemical property Harsh-temperature operation Operando characterization