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Ghost spintronic THz-emitter-array microscope

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Light(Science & Applications) 2020年第1期9卷 1057-1065页

作者： Si-Chao Chen Zheng Feng Jiang Li Wei Tan liang-Hui Du Jianwang Cai Yuncan ma Kang He Haifeng Ding Zhao-Hui Zhai Ze-Ren Li Cheng-Wei Qiu Xi-Cheng Zhang Li-Guo Zhu Institute of Fluid Physics China Academy of Engineering PhysicsMianyang 621900 SichuanChina Department of Optics and Optical Engineering University of Science and Technology of ChinaHefei 230026 AnhuiChina Microsystem&Terahertz Research Center China Academy of Engineering PhysicsChengdu 610200 SichuanChina Beijing National Laboratory for Condensed matter Physics Institute of PhysicsChinese Academy of Sciences100190 BeijingChina National Laboratory of Solid-State Microstructures and Department of Physics Nanjing UniversityNanjing 210093 JiangsuChina Department of Electrical and Computer Engineering National University of Singapore4 Engineering Drive 3Singapore 117583Singapore The Institute of Optics University of RochesterRochesterNY 14627USA

Terahertz(THz)waves show great potential in nondestructive testing,biodetection and cancer *** recent progress in THz wave near-field probes/apertures enabling raster scanning of an object’s surface,an efficient,nonscanning,noninvasive,deep subdiffraction imaging technique remains ***,we demonstrate THz near-field microscopy using a reconfigurable spintronic THz emitter array(STEA)based on the computational ghost imaging *** illuminating an object with the reconfigurable STEA followed by computing the correlation,we can reconstruct an image of the object with deep subdiffraction *** applying an external magnetic field,inline polarization rotation of the THz wave is realized,making the fused image contrast ***-of-flight(TOF)measurements of coherent THz pulses further enable objects at different distances or depths to be *** demonstrated ghost spintronic THz-emitter-array microscope(GHOSTEAM)is a radically novel imaging tool for THz near-field imaging,opening paradigm-shifting opportunities for nonintrusive label-free bioimaging in a broadband frequency range from 0.1 to 30 THz(namely,3.3-1000 cm^(−1)).

关键词： ghost Ghost GHOST

High capacity sodium-rich layered oxide cathode for sodium-ion batteries

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Chinese Physics B 2018年第11期27卷 665-671页

作者： Gen-Cai Guo Changhao Wang Bang-ming ming Si-Wei Luo Heng Su Bo-Ya Wang ming Zhang Hai-Jun Yu Ru-Zhi Wang College of materials Science and Engineering Beijing University of Technology Beijing 100124 China

Sodium-ion batteries have attracted significant recent attention currently considering the limited available lithium resource. However, the energy density of sodium-ion batteries is still insufficient compared to lithium-ion batteries, mainly because of the unavailability of high-energy cathode materials. In this work, a novel sodium-rich layered oxide material（Na_2 MnO_3） is reported with a dynamical stability similar to that of the Li_2 MnO_3 structure and a high capacity of269.69 ma·h·g1, based on first-principles calculations. Sodium ion de-intercalation and anionic reaction processes are systematically investigated, in association with sodium ions migration phenomenon and structure stability during cycling of Nax MnO3（1 ≤ x ≤ 2）. In addition, the charge compensation during the initial charging process is mainly contributed by oxygen, where the small differences of the energy barriers of the paths 2 c→4 h, 4 h→2 c, 4 h→4 h, 2 c→2 b, and 4 h→2 b indicate the reversible sodium ion occupancy in transitional metal and sodium layers. Moreover, the slow decrease of the elastic constants is a clear indication of the high cycle stability. These results provide a framework to exploit the potential of sodium-rich layered oxide, which may facilitate the development of high-performance electrode materials for sodium-ion batteries.

关键词： sodium-rich layered oxides first-principles calculations sodium-ion diffusion

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升力体外形设计的代理模型优化方法

宇航学报 2011年第7期32卷 1435-1444页

作者：张珍铭丁运亮刘毅南京航空航天大学飞行器先进设计技术国防重点学科实验室南京210016 同济大学航空航天与力学学院上海200092

面向飞行器概念设计提出了一种将类型函数/形状函数变换技术与代理模型技术及全局优化算法相结合,实现升力体外形多目标优化的设计策略。类型函数/形状函数变换技术能够通过调整少量尺寸参数或类型函数/形状函数控制参数衍生出多种设计... 详细信息

面向飞行器概念设计提出了一种将类型函数/形状函数变换技术与代理模型技术及全局优化算法相结合,实现升力体外形多目标优化的设计策略。类型函数/形状函数变换技术能够通过调整少量尺寸参数或类型函数/形状函数控制参数衍生出多种设计构型。选用最优拉丁超立方抽样完成实验设计,将径向基函数作为近似方法构建代理模型,并通过序贯采样后验策略改善代理模型拟合优度。在ma 6,迎角20°设计点处搭建了升力体简化外形的气动分析代理模型。应用NSGA-Ⅱ多目标遗传算法实现了以升阻比和容积利用率最大化为目标的折衷优化,得到包含一系列改进设计方案的Pareto-解集,其中,各构型目标响应相对实际分析值误差均在6.1%以内,表明该方法既可以通过代理模型大幅提升设计效率,降低应用全局优化算法的计算复杂度,又能够得到满足概念设计精度需要的设计方案,有利于概念设计中定量高效地实现多个设计目标的折衷优化,明确飞行器外形修改方向。

关键词：飞行器概念设计升力体类型函数/形状函数代理模型多目标优化气动外形优化

基于PHF-LSM-MT法岩石材料细观边界建模与水力裂缝扩展研究

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东北大学学报（自然科学版） 2022年第10期43卷 1461-1468页

作者：李明赵岐陈昭梁力东北大学资源与土木学院辽宁沈阳110819

天然非均质岩石具有复杂的细观结构和分布特征,本文结合柏林噪声建立考虑非规则边界的颗粒几何模型,实现考虑任意粒径、长短半轴、倾角和平面填充率的非规则颗粒填充.基于完全流-固耦合弹塑性理论,在已有的PHF-LSM(permeability-based h... 详细信息

天然非均质岩石具有复杂的细观结构和分布特征,本文结合柏林噪声建立考虑非规则边界的颗粒几何模型,实现考虑任意粒径、长短半轴、倾角和平面填充率的非规则颗粒填充.基于完全流-固耦合弹塑性理论,在已有的PHF-LSM(permeability-based hydraulic fracture level set method)模型基础上,通过引入MT(Mori-Tanaka)均匀化方法考虑积分点有效范围内细观尺度的材料分布特征,进而建立了PHF-LSM-MT非均质岩石材料细观特征建模及其水力压裂过程模拟方法.结合误差分析验证了该方法的可行性,在此基础上对非均质岩石材料进行了水力压裂过程模拟,得到了等效开裂区域.模拟结果表明:注水点水压力呈先升高后降低的趋势,起裂压力随包裹体体积分数增加而降低.

关键词：水力压裂细观建模柏林噪声岩石材料界面 PHF-LSM

传统的坚守:中国现代中小学语文课程中文言文地位的演变(1904-1949)

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河北师范大学学报（教育科学版） 2013年第3期15卷 21-25页

作者：梁尔铭井冈山大学教育学院江西吉安343009

《奏定学堂章程》的颁行,标志着中国现代语文课程的出现,白话文开始进入中小学语文课程当中。但中国现代中小学语文课程的转型,并非简单地以白话文代替了文言文。文言文未曾退出中小学语文课程的舞台,白话文也从未一枝独秀。在《奏定学... 详细信息

《奏定学堂章程》的颁行,标志着中国现代语文课程的出现,白话文开始进入中小学语文课程当中。但中国现代中小学语文课程的转型,并非简单地以白话文代替了文言文。文言文未曾退出中小学语文课程的舞台,白话文也从未一枝独秀。在《奏定学堂章程》颁行以后的半个世纪里,文言文在中国现代中小学语文课程当中仍然占据着重要地位。

关键词：现代化语文课程文言文白话文

Clinical efficacy and bacterial flora characteristics of Huazhi Rougan granules in the intervention of moderately resistant to damp-heat nonalcoholic fatty liver disease

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Gastroenterology & Hepatology Research 2022年第3期4卷 1-10页

作者： Dan Zhao ming-Zhong Xiao Jian-liang Xu Chen-Xia Lu Department of Laboratory Medicine Hubei Provincial Hospital of Traditional Chinese MedicineWuhan 430061China Department of Hepatology Hubei Key Laboratory of The Theory and Application Research of Liver and Kidney in Traditional Chinese MedicineHubei Provincial Hospital of Traditional Chinese MedicineWuhan 430061China Affiliated Hospital of Hubei University of Traditional Chinese Medicine Wuhan 430061China Hubei Province Academy of Traditional Chinese Medicine Wuhan 430074China

Background:To explore the clinical efficacy of Huazhi Rougan granules in treating non-alcoholic fatty liver disease(NAFLD)and its effect on the oral and intestinal ***:48 patients who met the inclusion criteria were intervened with Huazhi Rougan granules,the liver and spleen CT ratio,Traditional Chinese medicine(TCM)syndrome,body mass index(BMI,WC,SMM,body fat percentage,visceral fat area),liver function,and blood lipid levels were compared before and after treatment,and the curative effect was evaluated;6 cases of NAFLD patients whose clinical efficacy after Huazhi Rougan granule intervention was effective were randomly selected,and the patient’s oral and intestinal samples were taken for further ***:After treatment,the total effective rate of clinical efficacy was 85.14%.The TCM symptoms of NAFLD patients were significantly alleviated compared with before treatment(P<0.05).There were statistically significant differences in ALT,AST,GGT,TC,and TG before and after treatment(P<0.01).After treatment,BW,BMI,WC,body fat percentage,visceral fat area,liver hardness,and fat attenuation index were significantly decreased(P<0.01).Oral-gut flora analysis showed:After treatment,the Shannon index of the gut microbial community increased(P<0.01).Compared with before treatment,the abundance of Firmicutes decreased,while the abundance of Bacteroidetes,Candidatus-Sa,and Tenericutes increased(P<0.05).At the genus level,the abundance of Bacteroides,Lactobacillus,and Bifidobacterium increased,and Streptococcus,Oribacterium,and Peptoanaerobacter decreased(P<0.05).Before and after treatment,the dominant bacterial phyla in the intestine were the same,including Bacteroidetes,Firmicutes,and *** abundance of Firmicutes and Roseburia decreased after treatment(P<0.05).Conclusions:Huazhi Rougan granules have a significant effect on the treatment of NAFLD,can improve liver function,reduce blood lipids,can effectively reduce body morphological indicators suc

关键词： non-alcoholic fatty liver disease Huazhi Rougan granule intestinal flora oral flora clinical observation

Gene Repair of iPSC Line with GARS (G294R) Mutation of CMT2D Disease by CRISPR/Cas9

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Current Medical Science 2023年第2期43卷 261-267页

作者： Pei-jie LU Pei ZHANG Yu-chun LIU Na JING Ya-nan GUO Peng-shuai WANG Lin-lin SU Qi GUO Qiang ma Yu-ming XU Shou-tao ZHANG School of Life Science Zhengzhou UniversityZhengzhou450001China Longhu Laboratory of Advanced Immunology Zhengzhou450001China Department of Neurology the First Affiliated Hospital of Zhengzhou UniversityZhengzhou450052China

Objective Charcot-marie-Tooth disease(CMT)severely affects patient activity,and may cause ***,no clinical treatment is available to reverse the disease *** combination of CRISPR/Cas9 and iPSCs may have therapeutic potential against nervous diseases,such as *** In the present study,the skin fibroblasts of CMT type 2D(CMT2D)patients with the c.880G>A heterozygous nucleotide mutation in the GARS gene were reprogrammed into iPSCs using three plasmids(pCXLE-hSK,pCXLE-hUL and pCXLE-hOCT3/4-shp5-F).Then,CRISPR/Cas9 technology was used to repair the mutated gene sites at the iPSC *** An iPSC line derived from the GARS(G294R)family with fibular atrophy was successfully induced,and the mutated gene loci were repaired at the iPSC level using CRISPR/Cas9 *** findings lay the foundation for future research on drug screening and cell *** iPSCs can differentiate into different cell types,and originate from autologous ***,they are promising for the development of autologous cell therapies for degenerative *** combination of CRISPR/Cas9 and iPSCs may open a new avenue for the treatment of nervous diseases,such as CMT.

关键词： Charcot-marie-Tooth disease GARS CRISPR/Cas9 iPSCs gene therapy

Effect of multiple parameters on the supersonic gas-jet target characteristics for laser wakefield acceleration

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Nuclear Science and Techniques 2021年第7期32卷 90-98页

作者： Qiu-Shi Liu ming-Jiang ma Bao-Zhen Zhao Xiao-Hua Zhang Chong Lv Xiang-Hao Meng Ji Zhang Xiao-Na Ban Zhao Wang Xiao-Feng Xi Bao-Xian Tian Chuang-Ye He Bing Guo Department of Nuclear Physics China Institute of Atomic EnergyBeijing 102413China

The supersonic gas-jet target is an important experimental target for laser wakefield acceleration(LWFA),which has great potential for driving novel radiation sources such as betatron radiation and Compton scattering gamma *** to different electron acceleration requirements,it is necessary to provide specific supersonic gas jets with different density profiles to generate electron beams with high quality and high repetition *** this study,the interference images and density profiles of different gas-jet targets were obtained through a modified Nomarski interference diagnosis *** relationships between the gas density and back pressure,nozzle structure,and other key parameters were *** with different characteristics are conducive to meeting the various requirements of LWFA.

关键词： Supersonic gas-jet target Laser wakefield acceleration Electron acceleration Optical interference diagnosis

采用微型排水罩的药芯焊丝水下焊接焊缝自动跟踪系统

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机械工程学报 2007年第3期43卷 148-153页

作者：梁明王国荣钟继光华南理工大学机械工程学院广州510641

针对水下焊接图像噪声大、清晰度差的特殊情况,设计并研制成功一套药芯焊丝水下焊接的视觉传感焊缝自动跟踪系统。该系统由视觉传感、图像预处理及偏差识别系统,控制系统和执行机构等组成。采用小波多尺度变换进行水下焊缝图像边缘提取... 详细信息

针对水下焊接图像噪声大、清晰度差的特殊情况,设计并研制成功一套药芯焊丝水下焊接的视觉传感焊缝自动跟踪系统。该系统由视觉传感、图像预处理及偏差识别系统,控制系统和执行机构等组成。采用小波多尺度变换进行水下焊缝图像边缘提取,结果保留大多数的细节,得到有利于焊缝位置特征提取的预处理图像,在一种基于二值图像的焊缝中心位置识别算法计算后,得出焊缝偏差。在理论分析视觉传感焊缝自动跟踪系统模型的基础上,设计满足跟踪精度要求的规则自调整模糊算法。对影响跟踪系统精度的因素进行分析,并采用相应的措施以提高系统的精度。通过药芯焊丝湿法水下焊接焊缝自动跟踪试验表明,采用规则自调整模糊控制能够达到较高的焊缝跟踪精度。在斜线、折线和曲线三种不同形状待焊焊缝的跟踪试验中,系统都能满足药芯焊丝水下自动焊接的要求。经过改进微型排水罩,进行微型排水罩局部干法药芯焊丝水下焊接焊缝跟踪试验,采用规则自调整模糊控制,不仅得到满意的焊缝跟踪效果,还改善焊缝成形质量。

关键词：视觉传感焊缝跟踪水下焊接图像处理模糊控制微型排水罩