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Nano-Micro Letters 2025年第3期17卷 87-101页

作者： Kaibiao Xi Jianzhe Guo Mupeng zheng Mankang Zhu Yudong Hou Key Laboratory of Advanced Functional Materials Ministry of EducationCollege of Materials Science and EngineeringBeijing University of TechnologyBeijing 100124People’s Republic of China

High temperature piezoelectric energy harvester(HTPEH)is an important solution to replace chemical battery to achieve independent power supply of HT wireless ***,simultaneously excellent performances,including high figure of merit(FOM),insulation resistivity(ρ)and depolarization temperature(Td)are indispensable but hard to achieve in lead-free piezoceramics,especially operating at 250°C has not been reported ***,well-balanced performances are achieved in BiFeO3–BaTiO3 ceramics via innovative defect engineering with respect to delicate manganese *** to the synergistic effect of enhancing electrostrictive coefficient by polarization configuration optimization,regulating iron ion oxidation state by high valence manganese ion and stabilizing domain orientation by defect dipole,comprehensive excellent electrical performances(Td=340°C,ρ250°C>10^(7)Ωcm and FOM_(250°C)=4905×10^(–15)m^(2)N^(−1))are realized at the solid solubility limit of manganese *** HT-PEHs assembled using the rationally designed piezoceramic can allow for fast charging of commercial electrolytic capacitor at 250°C with high energy conversion efficiency(η=11.43%).These characteristics demonstrate that defect engineering tailored BF-BT can satisfy high-end HT-PEHs requirements,paving a new way in developing selfpowered wireless sensors working in HT environments.

关键词： Lead-free piezoceramic Defect engineering Dopants modulation High-temperature Piezoelectric energy harvester

AI-Enhanced Secure Data Aggregation for Smart Grids with Privacy Preservation

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Computers, Materials & Continua 2025年第1期82卷 799-816页

作者： Congcong Wang Chen Wang Wenying zheng Wei Gu School of Software Nanjing University of Information Science and TechnologyNanjing210044China School of Information Science and Engineering Zhejiang Sci-Tech UniversityHangzhou310018China State Key Laboratory of Public Big Data Guizhou UniversityGuiyang550025China School of Computer Science and Technology(School of Artificial Intelligence) Zhejiang Sci-Tech UniversityHangzhou310018China School of Computer Science(School of Cyber Science and Engineering) Nanjing University of Information Science and TechnologyNanjing210044China

As smart grid technology rapidly advances,the vast amount of user data collected by smart meter presents significant challenges in data security and privacy *** research emphasizes data security and user privacy concerns within smart ***,existing methods struggle with efficiency and security when processing large-scale *** efficient data processing with stringent privacy protection during data aggregation in smart grids remains an urgent *** paper proposes an AI-based multi-type data aggregation method designed to enhance aggregation efficiency and security by standardizing and normalizing various data *** approach optimizes data preprocessing,integrates Long Short-Term Memory(LSTM)networks for handling time-series data,and employs homomorphic encryption to safeguard user *** also explores the application of Boneh Lynn Shacham(BLS)signatures for user *** proposed scheme’s efficiency,security,and privacy protection capabilities are validated through rigorous security proofs and experimental analysis.

关键词： Smart grid data security privacy protection artificial intelligence data aggregation

褐藻糖胶对乳腺肿瘤大鼠肠道屏障损伤的保护作用

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营养学报 2018年第1期40卷 59-63页

作者：张婷薛美兰刘佳刘颖梁争艳梁惠青岛大学公共卫生学院青岛266021 青岛大学基础医学院青岛266071 青岛大学药学院青岛266021

目的探讨褐藻糖胶(fucoidan)对二甲基苯蒽(7,12-dimethylbenz(a)anthracene,DMBA)诱发的乳腺肿瘤大鼠肠道屏障损伤的保护作用。方法 60只雌性SD大鼠按体质量随机分为正常对照组(CN)、模型组(M)、低(F1)和高剂量(F2)褐藻糖胶干预组。M组... 详细信息

目的探讨褐藻糖胶(fucoidan)对二甲基苯蒽(7,12-dimethylbenz(a)anthracene,DMBA)诱发的乳腺肿瘤大鼠肠道屏障损伤的保护作用。方法 60只雌性SD大鼠按体质量随机分为正常对照组(CN)、模型组(M)、低(F1)和高剂量(F2)褐藻糖胶干预组。M组及F1、F2组,大鼠右侧臀部皮下一次性注射100 mg/kg DMBA建立乳腺癌模型,观察各组大鼠乳腺癌发生率及抑瘤率;HE染色观察大鼠空肠粘膜病理学改变;酶联免疫吸附实验(ELISA)检测血浆中D-乳酸(D-LA)和二胺氧化酶(DAO)水平;Western Blot法检测大鼠肠道紧密连接蛋白occludin及ZO-1表达。结果与模型组比较,F1、F2组大鼠肿瘤潜伏期均延长,肿瘤发生率和平均瘤重量降低(均P<0.05);抑瘤率分别达到34.5%和49.2%;M组大鼠肠壁受损,绒毛裸露且结构丧失,绒毛高度和隐窝深度降低,经褐藻糖胶干预后,小肠绒毛逐渐恢复栅栏样结构,其绒毛结构接近于CN组;与M组比较,F2组D-LA的浓度显著降低(P<0.05),F1、F2组DAO的浓度均显著降低(均P<0.05),F1、F2组occludin及ZO-1的表达均显著升高(P<0.05)。结论褐藻糖胶对大鼠乳腺肿瘤生长具有一定抑制作用,其作用机制可能修复乳腺癌大鼠受损的肠黏膜屏障相关。

关键词：褐藻糖胶乳腺癌肠道屏障紧密连接蛋白

双金属Ce-Mn/ZSM-5催化剂的制备及NH3-SCR脱硝性能研究

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燃料化学学报 2020年第2期48卷 205-212,I0006页

作者：梁彦正王学涛张乾蔚罗绍峰周瑜枫河南科技大学能源与动力工程系河南洛阳471003

采用浸渍法制备了铈锰复合氧化物分子筛催化剂(Ce-Mn/ZSM-5),在固定床反应器上考察不同Ce/Mn质量比对分子筛催化剂选择催化还原NO的影响,利用XRD、TEM、NH3-TPD、H2-TPR、in-situ DRIFTS等手段对催化剂进行了表征分析。结果表明,双金属... 详细信息

采用浸渍法制备了铈锰复合氧化物分子筛催化剂(Ce-Mn/ZSM-5),在固定床反应器上考察不同Ce/Mn质量比对分子筛催化剂选择催化还原NO的影响,利用XRD、TEM、NH3-TPD、H2-TPR、in-situ DRIFTS等手段对催化剂进行了表征分析。结果表明,双金属改性的Ce-Mn/ZSM-5催化剂在NH3-SCR反应中表现出较为优异的催化活性,具有较宽的活性温度窗口。当Ce/Mn质量比为0.4时,催化剂具有最佳的脱硝效率,在265-465℃脱硝率均可达到80%以上,在370℃时,NO的转化率最高可达97.28%。锰和铈物种高度分散于催化剂表面,未改变ZSM-5的晶体结构,且构成协同作用。0.4Ce-Mn/ZSM-5具备丰富的酸性位、良好的氧化还原性能,该配比有助于催化剂的催化活性和稳定性的提高,在NH3-SCR反应过程同时遵循E-R机理和L-H机理。

关键词：脱硝 Ce-Mn/ZSM-5 NH3-SCR 反应机理催化剂

提高瞬态红外设备检测GaNHEMT结温准确度的方法

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中国测试 2017年第5期43卷 20-25页

作者：翟玉卫梁法国刘岩郑世棋乔玉娥刘霞美中国电子科技集团公司第十三研究所计量中心河北石家庄050051

用高空间分辨率测温技术与瞬态红外设备测温结果结合的方法提高瞬态红外设备对GaN HEMT结温检测的准确度。对GaN HEMT随脉冲工作条件的结温变化规律进行分析,证明脉冲条件下器件各个位置的瞬时温度与平均温度呈线性关系;依据上述关系,... 详细信息

用高空间分辨率测温技术与瞬态红外设备测温结果结合的方法提高瞬态红外设备对GaN HEMT结温检测的准确度。对GaN HEMT随脉冲工作条件的结温变化规律进行分析,证明脉冲条件下器件各个位置的瞬时温度与平均温度呈线性关系;依据上述关系,采用各个位置的平均温度(高空间分辨率)对瞬态红外设备检测结果进行修正,有效提高瞬态红外设备检测GaN HEMT时的准确度。用有限元仿真结果验证上述方法的准确性。根据该方法,用高空间分辨率的显微红外测温结果对瞬态红外设备测温结果进行修正,实现2.8μm空间分辨率的瞬态温度检测。该方法可以有效提高瞬态红外设备检测GaN HEMT结温结果的准确度。

关键词：热学瞬态红外结温脉冲条件空间分辨率

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探讨行玻璃体切割术的重度玻璃体出血原因

糖尿病新世界 2017年第7期20卷 177-178页

作者：孙亮王彦郑姝婷王欣齐齐哈尔医学院朝聚眼科医院眼科黑龙江齐齐哈尔161041 杭州西湖朝聚眼科医院白内障科浙江杭州310000 齐齐哈尔医学院附属第一医院社区黑龙江齐齐哈尔161041 齐齐哈尔医学院附属第一医院神经外科黑龙江齐齐哈尔161041

目的该研究旨在通过对患有眼部疾病的患者在医院治疗的过程中玻璃体切割术出现的重度出血的原因进行分析,并提出相应的有效可行的处理措施,为合理处置玻璃体切割术的重度玻璃体出血提供一定的借鉴和指导。方法回顾该院收治的80例眼疾患... 详细信息

目的该研究旨在通过对患有眼部疾病的患者在医院治疗的过程中玻璃体切割术出现的重度出血的原因进行分析,并提出相应的有效可行的处理措施,为合理处置玻璃体切割术的重度玻璃体出血提供一定的借鉴和指导。方法回顾该院收治的80例眼疾患者的病例,对部分的临床资料进行回顾性分析,其中病变原因不明为7例,病变原因明确的为73例。结果对患者执行玻璃体切割术后观察近2个月,出现重度玻璃体出血的患者有9例,其他的71例术后恢复状况良好,7只眼的视力无提高。结论玻璃体切割的手术在有效治疗不同原因导致的重度玻璃体出血方面具有重要意义,可广泛应用于眼部疾病的临床治疗中。

关键词：玻璃体切割术重度玻璃体出血原因分析

冻干人用狂犬病疫苗(Vero细胞)冻干保护剂的筛选

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中国生物制品学杂志 2017年第3期30卷 225-228页

作者：李春艳赵淑洁孙宏亮闫峰郑华赵博柴博雅杨屹长春生物制品研究所有限责任公司疫苗研究室吉林长春130062

目的筛选适用于冻干人用狂犬病疫苗(Vero细胞)的冻干保护剂。方法用同一批冻干人用狂犬病疫苗(Vero细胞)原液在同一冻干条件下,改变右旋糖酐40、海藻糖及人血白蛋白3种保护剂主要成分的含量,组合成6种保护剂配方,分别制备成半成品。冻... 详细信息

目的筛选适用于冻干人用狂犬病疫苗(Vero细胞)的冻干保护剂。方法用同一批冻干人用狂犬病疫苗(Vero细胞)原液在同一冻干条件下,改变右旋糖酐40、海藻糖及人血白蛋白3种保护剂主要成分的含量,组合成6种保护剂配方,分别制备成半成品。冻干后检测成品外观、疫苗效力及热稳定性,确定最佳冻干保护剂配方。以最佳保护剂配方制备6批成品进行适用性验证,并选择3批成品进行长期稳定性验证。结果确定最佳冻干保护剂的配方为4%海藻糖、3%右旋糖酐40、1%蔗糖、0.5%甘露醇、2%人血白蛋白。以该配方制备的6批成品的各项检测指标均符合《中国药典》三部(2010版)的要求,其中3批成品经2~8℃保存12个月后的效价较稳定。结论筛选获得了最佳冻干人用狂犬病疫苗(Vero细胞)的冻干保护剂,且具有良好的稳定性。

关键词：冻干人用狂犬病疫苗(Vero细胞) 冻干保护剂稳定性

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4种粉体对醇溶性无机富锌漆耐蚀性能的影响

电镀与涂饰 2013年第7期32卷 70-73页

作者：田运霞陈玲梁正彦麻慧王佳庆燕山大学环境与化学工程学院河北秦皇岛066004

研究了石墨、磷铁粉、滑石粉和高钛灰取代醇溶性无机富锌漆中的部分球状锌粉对涂层耐蚀性的影响。通过耐盐水、耐盐雾以及开路电位–时间测试,研究了涂层的耐蚀性。结果表明,各粉体取代涂层都有一个最优取代比,且在最优取代比时涂层的... 详细信息

研究了石墨、磷铁粉、滑石粉和高钛灰取代醇溶性无机富锌漆中的部分球状锌粉对涂层耐蚀性的影响。通过耐盐水、耐盐雾以及开路电位–时间测试,研究了涂层的耐蚀性。结果表明,各粉体取代涂层都有一个最优取代比,且在最优取代比时涂层的阴极保护时间最长。导电粉取代涂层比非导电粉取代涂层的防腐效果更好。导电粉取代涂层的初始开路电位随取代比的增大先负移后正移,在最优取代比时达到最负值;非导电粉取代涂层的初始开路电位随着取代比的增大而逐渐正移。

关键词：无机富锌漆球状锌粉取代石墨磷铁粉滑石高钛灰耐蚀性

Optimizing the key parameter to accelerate the recovery of AMOC under a rapid increase of greenhouse gas forcing

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 39-45页

作者： Haolan Ren Fei zheng Tingwei Cao Qiang Wang International Center for Climate and Environment Science(ICCES) Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina University of Chinese Academy of Sciences BeijingChina College of Oceanography Hohai UniversityNanjingChina CAS Key Laboratory of Ocean Circulation and Waves Institute of OceanologyChinese Academy of Sciences and Pilot National Laboratory for Marine Science and Technology(Qingdao)QingdaoChina

Atlantic Meridional Overturning Circulation(AMOC)plays a central role in long-term climate variations through its heat and freshwater transports,which can collapse under a rapid increase of greenhouse gas forcing in climate *** studies have suggested that the deviation of model parameters is one of the major factors in inducing inaccurate AMOC *** this work,with a low-resolution earth system model,the authors try to explore whether a reasonable adjustment of the key model parameter can help to re-establish the AMOC after its *** a new optimization strategy,the extra freshwater flux(FWF)parameter is determined to be the dominant one affecting the AMOC’s *** traditional ensemble optimal interpolation(EnOI)data assimilation and new machine learning methods are adopted to optimize the FWF parameter in an abrupt 4×CO_(2) forcing experiment to improve the adaptability of model parameters and accelerate the recovery of *** results show that,under an abrupt 4×CO_(2) forcing in millennial simulations,the AMOC will first collapse and then re-establish by the default FWF parameter ***,during the parameter adjustment process,the saltier and colder sea water over the North Atlantic region are the dominant factors in usefully improving the adaptability of the FWF parameter and accelerating the recovery of AMOC,according to their physical relationship with FWF on the interdecadal timescale.

关键词： Recovery of AMOC 4×CO_(2)forcing Key parameter Parameter estimation Data assimilation Machine learning

Mechanism by which Rab5 promotes regeneration and functional recovery of zebrafish Mauthner axons

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Neural Regeneration Research 2025年第6期20卷 1816-1824页

作者： Jiantao Cui Yueru Shen zheng Song Dinggang Fan Bing Hu Center for Advanced Interdisciplinary Science and Biomedicine of IHM Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina

Rab5 is a GTPase protein that is involved in intracellular membrane trafficking. It functions by binding to various effector proteins and regulating cellular responses, including the formation of transport vesicles and their fusion with the cellular membrane. Rab5 has been reported to play an important role in the development of the zebrafish embryo;however, its role in axonal regeneration in the central nervous system remains unclear. In this study, we established a zebrafish Mauthner cell model of axonal injury using single-cell electroporation and two-photon axotomy techniques. We found that overexpression of Rab5 in single Mauthner cells promoted marked axonal regeneration and increased the number of intra-axonal transport vesicles. In contrast, treatment of zebrafish larvae with the Rab kinase inhibitor CID-1067700markedly inhibited axonal regeneration in Mauthner cells. We also found that Rab5 activated phosphatidylinositol 3-kinase(PI3K) during axonal repair of Mauthner cells and promoted the recovery of zebrafish locomotor function. Additionally, rapamycin, an inhibitor of the mechanistic target of rapamycin downstream of PI3K, markedly hindered axonal regeneration. These findings suggest that Rab5 promotes the axonal regeneration of injured zebrafish Mauthner cells by activating the PI3K signaling pathway.

关键词： axonal regeneration Mauthner cell nerve regeneration Rab5 zebrafish