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Global trend of nondrug and nonsedativehypnotic treatment forinsomnia: a bibliometric study

Journal of Traditional Chinese Medicine 2024年第3期44卷 595-608页

作者： LEI Hanzhou XU Guixing WEI Zepeng ZHAO Ling liang fanrong Acupuncture and Tuina School Chengdu University of Traditional Chinese Medicine Department of Haematology Royal North Shore Hospital

OBJECTIVE: To present a bibliometric analysis of global scientific publications on the nondrug and nonsedative hypnotic treatment of insomnia with regard to influential institutions, publications, countries, research hotspots,trends, and frontiers. METHODS: A literature review was conducted by searching the Web of Science Core Collection(Wo SCC) and China National Knowledge Infrastructure(CNKI) databases to identify all publications related to the nondrug and nonsedative hypnotic treatment of insomnia from 2000 to 2021. Eligible publications were reviewed, including annual publication increments, citation analyses, international collaborations, and keyword analyses. The data were analysed using Cite Space(vers5.8.R3, 6.1.R2 and 6.1.6, College of Computing and Informatics, Philadelphia, PA, USA) and virtualized by knowledge maps. RESULTS:In total, 9832 publications were included in this analysis. The results from the WoSCC showed that the United States of America(Count = 2268, 40.33%), Stanford University(Count = 141, 2.51%), and the United States Department of Health and Human Services were the leading country, institute, and funding agency regarding the number of publications, respectively. “Cognitive-behavioural therapy” was the most popular research topic generated from the cocited reference. The most frequently co-occurring keywords were insomnia, cognitive behavioural therapy, disorder, depression, quality of life, Meta-analysis, older adult, sleep, prevalence and efficacy, while keywords including clinical practice guideline, guideline, and Tai Chi remained popular after 2021. Circadian rhythm was the strongest research frontier for 2000-2021. In China, Chengdu University of Traditional Chinese Medicine(Count = 69, 4.79%) was the most productive institute in this field. The most frequently co-occurring keywords from Chinese literature were sleep disorder, sleep quality, acupuncture and moxibustion, Parkinson's disease, transcranial magnetic stimulation, health education, music therapy, chronic insomnia, qua

关键词： CiteSpace bibliometrics cognitive behavioral therapy complementary therapies hypnotics and sedatives scientometrics visualization analysis

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Mechanisms of immune regulation for acupuncture on chronic respiratory diseases

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Journal of Traditional Chinese Medicine 2022年第2期42卷 314-320页

作者： WEI Meng LI Yu XIONG Chan LIU Yefang liang fanrong MAO Bing MIAO Tiwei HUANG Ying ZHUYijing FU Juanjuan Chengdu University of Traditional Chinese Medicine No.3 Affiliated Hospital of Chengdu University of Traditional Chinese Medicine(West District)/Chengdu Pidu District Hospital of Traditional Chinese MedicineChengdu 611730China Respiratory Department No.3 Affiliated Hospital of Chengdu University of Traditional Chinese Medicine(West District)/Chengdu Pidu District Hospital of Traditional Chinese MedicineChengdu 611730China Department of Integrated Traditional and Western Medicine West China HospitalSichuan UniversityChengdu 610041China Acupuncture and Tuina School Chengdu University of Traditional Chinese MedicineChengdu 610053China

Chronic respiratory diseases(CRDs)are among the most common noncommunicable diseases globally,with high morbidity and mortality rates.Acupuncture,a treatment method derived from Traditional Chinese Medicine,has been shown to be effective at treating CRDs,with little risk of adverse effects.Scientific research on the mechanisms underlying the effects of acupuncture,especially,its immune regulatory function,has rapidly advanced in recent years.Herein,the diverse immune regulatory mechanisms underlying the beneficial effects of acupuncture are summarized from the perspectives of innate immunity,adaptive immunity,and neuroimmunity.A better understanding of these mechanisms will ultimately provide a scientific basis for the clinical use of acupuncture for the treatment of CRDs.

关键词： acupuncture immunity innate adaptive immunity neuroimmunomodulation chronic respiratory diseases

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Effect of catgut embedding at acupoints versus non-acupoints in abdominal obesity:a randomized clinical trial

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中医杂志:英文版 2023年第4期43卷 780-786页

作者： ZHANG Xinghe LI Qifu YI Rong XING Chonghui JIN Yuhao MENG Jiangqiong FENG Jialei ZHAO Siwen liang fanrong GUO Taipin School of Second Clinical Medicine/The Second Affiliated Hospital Yunnan University of Chinese MedicineKunming 650500China Department of Acupuncture and Moxibustion Kunming Hospital of Traditional Chinese MedicineKunming 650200China Department of Acupuncture and Moxibustion the Sports Trauma Specialist Hospital of Yunnan ProvinceKunming 650051China Institute for History of Medicine and Medical Literature China Academy of Chinese Medical SciencesBeijing 100027China School of Acupuncture and Tuina Chengdu University of Traditional Chinese MedicineChengdu 610075China

OBJECTIVE:To explore the difference of catgut embedding effect between acupoints and non-acupoints in patients with abdominal obesity(AO).METHODS:In this multicenter,double-blind,randomized controlled trial,all subjects were randomly assigned into the acupoint catgut embedding(ACE)group and control group(catgut embedding at non-acupoints).With a 12-week actual intervention period and a 4-week period of follow-up.Waist circumference(WC),body weight,body mass index(BMI),hip circumference(HC)and appetite were applied and assessed at baseline and after 6,12 and 16 weeks.RESULTS:After the total intervention phase(12 weeks),the WC,body weight,BMI,HC and visual analogue scale scores of appetite,decreased significantly in the two groups as compared to the baseline(P<0.001).Meanwhile,after the 4-week follow-up,the indicators still decreased significantly in the ACE group(P<0.001).At 12 and 16 weeks,catgut embedding at acupoints showed significantly advantages to non-acupoints in WC and appetite(P<0.05).No serious adverse events were observed in ACE group and control group.CONCLUSIONS:Catgut embedding at acupoints and non-acupoints are all effective and safe for AO.ACE can effectively treat AO as expected and deliver lasting results.

关键词： acupoint catgut embedding non-acupoints obesity abdominal waist circumference randomized controlled trial

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Cerebral fractional amplitude of low-frequency fluctuations may predict headache intensity improvement following acupuncture treatment in migraine patients

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Journal of Traditional Chinese Medicine 2020年第6期40卷 1041-1051页

作者： Li Zhengjie Zhou Jun Cheng Shirui Lan Lei Sun Ruirui Liu Mailan Yang Jie Gao Yujie Guo Taipin Gong Qiyong Zeng Fang liang fanrong Acupuncture&Tuina School/The Third Teaching Hospital Chengdu University of Traditional Chinese MedicineChengdu 610000China Acupuncture&Tuina School Hunan University of Chinese MedicineChangsha 410000China Huaxi Magnetic Resonance Research Center West China Hospital of Sichuan UniversityChengdu 610000China

OBJECTIVE:To explore how baseline resting-state cerebral function predicts clinical outcomes of acupuncture treatment for migraine.METHODS:One hundred migraine patients and 46 healthy subjects were recruited.Patients were randomized into the acupuncture,sham acupuncture,and waiting list groups.Resting-state functional magnetic resonance imaging data were collected at baseline and after 1 month of longitudinal acupuncture treatments.Fractional amplitude of low-frequency fluctuations(f ALFF)calculations were applied to explore the associations between baseline f ALFF and changes in clinical variables in the acupuncture treatment group and the waiting list group.RESULTS:Compared with healthy subjects,migraine patients had lower f ALFF in the left rostral ventromedial medulla,right thalamus,left amygdala,and right angular gyrus.Regression analyses revealed that baseline f ALFF values in the left middle frontal gyrus,left superior temporal gyrus,and middle temporal gyrus were positively associated with headache intensity changes in the acupuncture treatment group,while baseline f ALFF values in the bilateral lingual gyrus and cuneus were negatively associated with headache intensity changes in this group.CONCLUSION:The baseline f ALFF values of brain regions associated with cognitive pain modulation,but not migraine severity,may predict future headache intensity improvement levels in migraine patients receiving acupuncture treatment.

关键词： Acupuncture Migraine disorders Treatment outcome Magnetic resonance imaging

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Effect of acupuncture at Neiguan (PC 6) on cardiac function using echocardiography in myocardial ischemia rats induced by isoproterenol

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Journal of Traditional Chinese Medicine 2015年第6期35卷 653-658页

作者： Wang Songzi Ren Lu Jia Lianqun Gu Zhongyue Fan Xu Chen Wenna Hou Ping liang fanrong Rong Peijing Ma Tieming Liu Xulai Chen Yiguo Department of Acupuncture and Moxibustion Liaoning University of Traditional Chinese Medicine Experimental Center Liaoning University of Traditional Chinese Medicine Vasculocardiology Department Liaoning Hospital of Traditional Chinese Medicine Affiliated to Liaoning University of Traditional Chinese Medicine Department of Acupuncture and Moxibustion Chengdu University of Traditional Chinese Medicine Department of Acupuncture and Moxibustion China Academy of Chinese Medical Sciences

OBJECTIVE: To investigate the effect of acupuncture at Neiguan(PC 6) on cardiac function using echocardiography in rat models of myocardial ischemia(MI) induced by isoproterenol(ISO).METHODS: Twenty-seven Sprague-Dawley rats were randomly assigned to normal, model, and acupuncture groups. The model and acupuncture groups were given injections of ISO(85 mg/kg) to establish the MI model. After model establishment,the acupuncture group was treated with acupuncture at Neiguan(PC 6) for 30 min. Echocardiography was used to monitor diastolic and systolic function for 30 min starting from the time after the acupuncture needles were removed. Changes in the length of left ventricular internal diameter at end-diastole(LVIDd), length of left ventricular internal diameter at end-systole(LVIDs), the ratio of mitral peak velocity at early diastole and atrial contraction(E/A), ejection fraction(EF), fractional shortening(FS), and stroke volume(SV) were measured.RESULTS: Compared with the model group at 0and 15 min after needles were removed, the means of LVIDd and LVIDs were significantly lower(P <0.01) and E/A, EF, FS, and SV significantly higher(P < 0.01) in the acupuncture group. In the acupuncture group, the means of LVIDd and LVIDs15 min after the needles were removed were significantly higher(P < 0.01) than those at 0 min. The means of E/A, EF, FS, and SV significantly decreased(P < 0.01) from 0 to 15 min in the acupuncture group.CONCLUSION: These findings indicate that acupuncture at Neiguan(PC 6) can affect cardiac function by increasing left ventricular diastolic and systolic function in MI rat models, but the effect only lasts for 15 min.

关键词： Acupuncture Point PC 6 (Neiguan) Myocardial ischemia Heart function tests Echocar-diography Isoproterenol

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针刀治疗强直性脊柱炎探析

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山东中医杂志 2024年第6期43卷 613-617页

作者：李书豪梁繁荣成都中医药大学针灸推拿学院四川成都610075

近年来,针刀疗法在强直性脊柱炎(AS)的治疗中应用广泛。针刀疗法起源于中医“九针”之“锋针”,结合西医解剖学理论,不断对疾病进行现代化多元解读,是中医技术现代化的探索之一。本文先从中医角度分析AS的病因病机,再从西医角度论述AS... 详细信息

近年来,针刀疗法在强直性脊柱炎(AS)的治疗中应用广泛。针刀疗法起源于中医“九针”之“锋针”,结合西医解剖学理论,不断对疾病进行现代化多元解读,是中医技术现代化的探索之一。本文先从中医角度分析AS的病因病机,再从西医角度论述AS的发病机制,继而根据中西医对AS发病的不同认识,阐释针刀治疗AS“辨经论治”和“辨构论治”的机制,并回顾总结相关临床疗效,以期为临床治疗AS提供参考。

关键词：强直性脊柱炎针刀病因病机辨经论治辨构论治治疗机制

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Effect of acupuncture plus conventional treatment on brain activity in ischemic stroke patients: a regional homogeneity analysis

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Journal of Traditional Chinese Medicine 2017年第5期37卷 650-658页

作者： Wu Ping Zeng Fang Li Yongxin Li Ji Qiu Lihua Qin Wei Luo Lu Yin Canxin Xiong Yan Bai Yu Wang Dan Zhou Yumei liang fanrong Department of Acupuncture and Tuina Chengdu University of Traditional Chinese Medicine Institute of Clinical Anatomy School of Basic Medical Sciences Southern Medical University Department of Acupuncture and Rehabilitation The First Teaching Hospital Chengdu University of Traditional Chinese Medicine Radiology Department West China Hospital of Sichuan University Life Sciences Research Center School of Life Sciences and Technology Xidian University China Academy of Chinese Medical Sciences World Federation of Acupuncture-Moxibustion Societies

OBJECTIVE: To determine differences in cerebral activity evoked by acupuncture and conventional stroke treatment, and identify the treatment targets.METHODS: In total, 21 patients were randomly divided into two groups. Group A(11 patients) received both acupuncture and conventional treatment, while group B(10 patients) received conventional treatment only. Resting-state functional magnetic resonance imaging(f MRI) was performed on each participant before and after treatment. Regional homogeneity analysis was performed to investigate the potential mechanism of acupuncture treatment by comparing differences in cerebral activity between treatments.RESULTS: Group A showed higher Re Ho in the frontal lobe(BA6, BA46), supra-marginal gyrus(BA40),middle temporal gyrus(BA21), cerebellum, and insula. Group B showed higher Re Ho in the frontal lobe(BA6) and parietal lobe(BA3, BA7).CONCLUSION: Acupuncture and conventional treatment triggered relatively different clinical efficacy and brain responses. Acupuncture treatment more significantly improved the symptoms of stroke patients. More marked changes in sensory,emotional, and motor areas(including the frontal lobe, middle temporal gyrus, cerebellum, and insula) might reflect the specific acupuncture mechanism.

关键词：针灸磁性的回声成像击服的活动地区性的同质分析

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针刺治疗慢性阻塞性肺疾病的机制研究进展

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上海中医药杂志 2024年第6期58卷 12-16页

作者：杨佐琴徐桂兴付雪何斌秦尔奇余曙光梁繁荣成都中医药大学附属第三医院/成都中医药大学第三临床医学院/成都市郫都区中医医院针灸科四川成都611730 成都中医药大学针灸推拿学院四川成都610075 四川省针灸临床医学研究中心四川成都610075

慢性阻塞性肺疾病(COPD)是一种以持续性呼吸困难伴咳嗽及痰液生成为主要症状的进展性的气道反应疾病。针刺作为一种非药物疗法在COPD治疗中扮演越来越重要的角色。目前针刺治疗COPD的机制研究主要集中在炎症、免疫调节、氧化应激等方面... 详细信息

慢性阻塞性肺疾病(COPD)是一种以持续性呼吸困难伴咳嗽及痰液生成为主要症状的进展性的气道反应疾病。针刺作为一种非药物疗法在COPD治疗中扮演越来越重要的角色。目前针刺治疗COPD的机制研究主要集中在炎症、免疫调节、氧化应激等方面,针刺通过以上调节机制作用于气道平滑肌,减轻其痉挛从而改善气流限制,改善肺部及全身炎症性反应而发挥治疗作用,但针刺的作用机制仍有待进一步深入研究。对针刺治疗COPD的相关机制研究进行梳理归纳,以期为揭示针刺治疗COPD的相关机制提供一定依据。

关键词：慢性阻塞性肺疾病针刺非药物疗法炎症反应免疫调节作用机制

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基于“任主胞胎”的电针周期疗法联合枸橼酸氯米芬治疗多囊卵巢综合征的临床疗效观察

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中华中医药杂志 2024年第1期39卷 496-499页

作者：陈姣范华英曾玖芝刘渝胡金群周旻庆黄娟梁繁荣成都中医药大学成都610075 四川省妇幼保健院成都610000

目的:探讨基于“任主胞胎”的电针周期疗法联合枸橼酸氯米芬治疗多囊卵巢综合征(PCOS)的临床疗效。方法:将116例患者随机分为试验组和对照组,各58例。对照组采用枸橼酸氯米芬治疗,试验组在对照组基础上联合基于“任主胞胎”的电针周期... 详细信息

目的:探讨基于“任主胞胎”的电针周期疗法联合枸橼酸氯米芬治疗多囊卵巢综合征(PCOS)的临床疗效。方法:将116例患者随机分为试验组和对照组,各58例。对照组采用枸橼酸氯米芬治疗,试验组在对照组基础上联合基于“任主胞胎”的电针周期疗法。针灸治疗每周3次,经期停刺,1个月经周期为1个疗程,连续治疗3个疗程。观察两组治疗前后排卵率、血清性激素水平、妊娠率、优势卵泡大小和早期流产率。结果:治疗后,试验组排卵率、优势卵泡大小、妊娠率显著高于对照组(P<0.05),但两组的早期流产率差异无统计学意义;试验组血清性激素水平(除黄体生成素外)改善程度显著优于对照组(P<0.05)。结论:基于“任主胞胎”的电针周期疗法联合枸橼酸氯米芬能有效改善PCOS患者的血清性激素水平,降低高雄激素状态,促进患者优势卵泡生长,提高其临床排卵率及妊娠率。

关键词：电针周期疗法多囊卵巢综合征任主胞胎不孕

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Functional brain imaging studies on specificity of meridian and acupoints

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Neural Regeneration Research 2008年第7期3卷 777-781页

作者： Xuezhi Li Xuguang Liu fanrong liang Chengdu University of Traditional Chinese Medicine Chengdu 610075 Sichuan Province China College of Traditional Chinese Medicine Chongqing Medical University Chongqing 400016 China

At present, the specificity of meridians and acupoints has been studied using functional brain imaging techniques from many standpoints, including meridians, acupoints, and sham acupoints, as well as different meridians and acupoints, coordination of acupoints, and factors influencing meridian and acupoint specificity Preliminary experimental data have demonstrated that acupuncture at meridians and acupoints is specific with regard to brain neural information. However, research findings are contradictory, which may be related to brain functional complexity, resolution of functional brain imaging techniques, and experimental design. Future studies should further improve study method, and should strictly control experimental conditions to better analyze experimental data and acquire more beneficial data. Because of its many advantages, the functional brain imaging technique is a promising method for studying meridian and acupoint specificity.

关键词： meridians and acupoints effect specificity functional brain imaging

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