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Microstructural Evolution of Gas Atomized Fe-25Cr-3.2C Alloy Powders

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Journal of Iron and Steel Research(International) 2011年第2期18卷 75-78页

作者： YANG Min SONG chang-jiang DAI Yong-xiang ZHU liang LI Ke-feng ZHAI Qi-jie Shanghai Key Laboratory of Modern Metallurgy and Materials Processing Shanghai University Shanghai 200072 China

The microstructural evolution of the gas atomized Fe-25Cr-3.2C powders was investigated by using optical microscope, scanning electron microscope, and X-ray diffraction. The experimental results showed that the atomized Fe-25Cr-3.2C powders were mainly composed of austenite and （Fe,Cr）7 C3 carbide. Eutectic microstructure was developed in the larger particles, whereas dendritic microstrueture was obtained in the particles with diameter less than 38 μm. The reason for microstructure change should be the difference of nucleation undercooling for particles.

关键词： gas atomization Fe-Cr-C alloy microstructure undercooling rapid solidification

Effects of Roughly Focused Extracorporeal Shock Waves Therapy on the Expressions of Bone Morphogenetic Protein-2 and Osteoprotegerin in Osteoporotic Fracture in Rats

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Chinese Medical Journal 2016年第21期129卷 2567-2575页

作者： Hai-Ming Huang Xiao-Lin Li Shu-Qiang Tu Xiao-Feng Chen chang-Chun Lu liang-Hua Jiang Department of Orthopedic Surgery Nanchang Hongdu Hospital of Traditional Chinese Medicine Nanchang Jiangxi 330006 China Department of Ortllopedic Surgery Shangtlai Sixth People's Hospital Shanghai Jiao Tong University Shanghai200233 China Department of Orthopedic Surgery Kunshan First People's Hospital Suzhou Jiangsu 215300 China

Background：Roughly focused extracorporeal shock waves therapy （ESWT） is characterized by a wide focal area,a large therapy zone,easy positioning,and less pain during *** purpose of this study was to investigate the effects of roughly focused ESWT on the expression of osteoprotegerin （OPG） and bone morphogenetic protein-2 （BMP-2） in osteoporotic fractures in ***：Seventy-two female Sprague-Dawley （SD） rats,3 months old,were divided into sham-operated group （n =6） and an ovariectomized （OVX） group （n =66）.Sixty OVX SD rats were used as a model of double proximal tibial osteotomy and inner *** osteotomy site in the left tibia was treated with roughly focused ESWT once at an energy density of 0.26 mJ/mm^2,60 doses/min,and 2000 pact *** contralateral right tibia was left untreated and served as a *** of OPG and BMP-2 in the callus of the osteoporotic fracture area was assessed using immunohistochemistry,real-time polymerase chain reaction （PCR）,and Western blotting ***：Bone mineral density （BMD） at the proximal tibia,femur,and L5 spine was significantly reduced after *** of proximal tibia was 12.9% less in the OVX group than that in the sham-operated ***,bilateral oophorectomy resulted in a lower trabecular bone volume fraction （BV/TV） in the proximal tibia of the sham-OVX *** months after bilateral oophorectomy,BV/TV was 14.29% of baseline BV/TV in OVX legs versus 45.91% in the sham-OVX legs （P 〈 0.001）.These data showed that the SD rats became a suitable model of osteoporosis,3 months after they were *** analysis showed higher levels of BMP-2 and OPG expression in the treatment group than those in the control *** with the contralateral controls,decreased expression of OPG and BMP-2 at 3 days after roughly focused ESWT,followed by a later increase at 7 days,was indicated by real-time PCR and Western blotting *** OPG messenger RNA （m

关键词： Bone Morphogenetic Protein-2 Extracorporeal Shock Waves Therapy Fracture Healing Osteoporotic Fracturc Osteoprotegerin

Experimental demonstration of dissipative sensing in a self-interference microring resonator

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Photonics Research 2018年第7期6卷 681-685页

作者： SHUAI WAN RuI NIU HONG-liang REN chang-LING Zou GUANG-CAN Guo CHUN-HUA DONG Key Laboratory of Quantum Information University of Science and Technology of ChinaChinese Academy of SciencesHefei 230026China College of Information Engineering Zhejiang University of TechnologyHangzhou 310023China Synergetic Innovation Center of Quantum Information and Quantum Physics University of Science and Technology of ChinaHefei 230026China

The dissipative sensing based on a self-interference microring resonator composed of a microring resonator and a U-shaped feedback waveguide is demonstrated experimentally. Instead of a frequency shift induced by the phase shift of the waveguide or the microcavity, the dissipative sensing converts the phase shift to the effective external coupling rate, which leads to the change of linewidth of the optical resonance and the extinction ratio in the transmission spectrum. In our experiment, the power dissipated from a microheater on the feedback waveguide is detected by the dissipative sensing mechanism, and the sensitivity of our device can achieve0.22 d B/m W. This dissipative sensing mechanism provides another promising candidate for microcavity sensing applications.

关键词：微环谐振器波导结构通讯技术技术分析

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无刷直流电机控制系统的可靠通信

微电机 2004年第1期37卷 29-32页

作者：夏长亮陈炜王娟徐绍辉天津大学电气与自动化工程学院天津300072

介绍了一种基于汉明码的快速而有效的检错方法,结合反馈重传(ARQ)差错控制方式,将其应用于无位置传感器无刷直流电机DSP控制器与上位机之间的通信过程中,能够明显提高通信速度和可靠性,使该控制系统可以在基本不损失动态性能的前提下,... 详细信息

介绍了一种基于汉明码的快速而有效的检错方法,结合反馈重传(ARQ)差错控制方式,将其应用于无位置传感器无刷直流电机DSP控制器与上位机之间的通信过程中,能够明显提高通信速度和可靠性,使该控制系统可以在基本不损失动态性能的前提下,稳定地运行于有较强电磁干扰的场合中。

关键词：无刷直流电机控制系统差错控制 DSP 通信可靠性控制器

伴不同程度焦虑症状的抑郁症患者文拉法辛的疗效比较

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临床精神医学杂志 2020年第1期30卷 57-59页

作者：李仙季长亮侯亚婷王永江曾淑娥杨蜀云云南省精神病医院

目的:比较伴不同程度焦虑症状的抑郁症患者文拉法辛的疗效。方法:224例抑郁症患者根据汉密尔顿焦虑量表(HAMA)评分分为明显焦虑组(HAMA≥14分,158例)及可能焦虑组(HAMA<14分,66例),均给予文拉法辛单药治疗52周。治疗前进行汉密尔顿抑郁... 详细信息

目的:比较伴不同程度焦虑症状的抑郁症患者文拉法辛的疗效。方法:224例抑郁症患者根据汉密尔顿焦虑量表(HAMA)评分分为明显焦虑组(HAMA≥14分,158例)及可能焦虑组(HAMA<14分,66例),均给予文拉法辛单药治疗52周。治疗前进行汉密尔顿抑郁量表-17(HAMD-17)、HAMA和自杀意念自评量表(SIOSS)测评;以治疗后HAMD减分率≥50%为有效;治疗后第2周末HAMD减分率≥25%为早期起效;比较两组治疗后第2、4、8、12、52周时的疗效。结果:明显焦虑组146例(91.78%)、可能焦虑组61例(91.80%)完成随访;明显焦虑组的自杀风险率(60.1%)显著高于可能焦虑组(25.8%)(P<0.01);治疗前后各时间点HAMD评分显著高于可能焦虑组(P<0.05或P<0.01);治疗后早期起效率(治疗后2周)、持续有效率(治疗后4周)、临床痊愈率(治疗后8周)、持续临床痊愈率(治疗后12周)显著低于可能焦虑组(P均<0.05);复发率(29.1%)显著高于可能焦虑组(15.2%)(P<0.05)。结论:文拉法辛对无或伴轻度焦虑症状的抑郁症患者疗效明显好于伴有明显焦虑症状的患者。

关键词：抑郁症焦虑疗效

Convenient Synthesis of Substituted Quinoxalines and 2H-Benzo[b][1,4]oxazines in Water

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Chemical Research in Chinese Universities 2009年第2期25卷 174-177页

作者： DING chang-jiang WANG Yan ZHANG Wei-wei LIU Li liang Yong-jiu DONG De-wen College of Chemistry Jilin University Changchun 130012 P. R. China changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 130022 P. R. China

A facile and convenient synthesis method has been developed for substituted quinoxalines and 2H-benzo[b][1,4]oxazines from the reactions of a-bromoketones with benzene-1,2-diamine and 2-aminophenol, respectively, whic... 详细信息

关键词： Quinoxaline Benzene-l,2-diamine 2-Aminophenol a-Bromoketone Water

RGF1-RGI1,a Peptide-Receptor Complex,Regulates Arabidopsis Root Meristem Development via a MAPK Signaling Cascade

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Molecular Plant 2020年第11期13卷 1594-1607页

作者： Xiaoting Lu Hongyong Shi Yang Ou Yanwei Cui Jinke chang liang Peng Xiaoping Gou Kai He Jia Li Ministry of Education Key Laboratory of Cell Activities and Stress Adaptations School of Life SciencesLanzhou UniversityLanzhou 730000China

Root growth is maintained by the continuous division of cells in the apical *** MERISTEM GROWTH FACTOR 1(RGF1)is a critical peptide hormone regulating root stem cell niche *** studies discovered that five closely related leucine-rich repeat receptor-like protein kinases(LRRRLKs),named RGF1 INSENSITIVES(RGIs)or RGF1 RECEPTORS(RGFRs),are able to perceive the RGF1 signal and redundantly control root stem cell niche ***1 regulates root meristem activity mainly via two downstream transcription factors,PLETHORA 1(PLT1)and *** proteins connecting cell surface RGF1-RGI1 and nuclear PLTs,however,were not ***,we report that the mitogen-activated protein(MAP)kinase kinase 4(MKK4)and MAP kinase 3(MPK3)were coimmunoprecipitated with RGI1-FLAG after Arabidopsis seedlings were treated with *** and biochemical assays confirmed that MKK4 and MKK5,and their downstream targets MPK3 and MPK6,are essential RG卜dependent regulators of root meristem *** addition,we found that the MKK4/MKK5-MPK3/MPK6 module functions downstream of YDA,a *** results demonstrate that RGF1-RGI1 regulate the expression of PLT1/PLT2 via a YDA-MKK4/MKK5-MPK3/MPK6 signaling cascade.

关键词： root meristem RGF1 RGI1 RLK MAPK

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个体化优选抗精神病药治疗方案的临床研究

临床精神医学杂志 2020年第3期30卷 145-149页

作者：梁昌权侯彩兰凌侬喜郭美萍陈雁迁唐京雄江门市新会区第三人民医院 529000 广东省精神卫生中心

目的:找出预测抗精神病药疗效和不良反应个体差异的易感基因组合,构建预测效率较高的抗精神病药个体化优选治疗方案。方法:选取2016年8月至2018年8月收治的精神分裂症患者244例,随机分配至利培酮、奥氮平、喹硫平、阿立哌唑治疗组,接受... 详细信息

目的:找出预测抗精神病药疗效和不良反应个体差异的易感基因组合,构建预测效率较高的抗精神病药个体化优选治疗方案。方法:选取2016年8月至2018年8月收治的精神分裂症患者244例,随机分配至利培酮、奥氮平、喹硫平、阿立哌唑治疗组,接受相应的单盲法2年药物治疗。采用基因多态性分析技术,结合临床量表评估和实验室检查,了解各药物的疗效、有效剂量和不良反应个体化差异。结果:利培酮组对于CYP2D6多态性最敏感(F=6.214,P=0.023),阿立哌唑组次之(F=4.415,P=0.042),其他两组无明显影响(P>0.05)。CYP1A2多态性仅对利培酮组平均血药浓度产生显著影响(F=5.019,P=0.041)。DRD2G-607T多态性对4组平均血药浓度均产生显著影响(P0.05)。但实验室检查显示4种药物造成的各种不良反应的程度不同。结论:对于CYP2D6亚型属于代谢较快型时,利培酮、奥氮平和阿立哌唑都可以下调给药量,利培酮可以下调更多。而对于CYP12A亚型属于代谢较快型时,利培酮可以适当小幅度下调给药量。

关键词：精神分裂症易感基因抗精神病药个体化治疗方案

时间-温度阈值控制肝脏激光间质热消融治疗的实验研究

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医学影像学杂志 2008年第1期18卷 75-78页

作者：林征宇武乐斌毕万利李成利梁长虎山东省医学影像学研究所山东济南250021

目的:探讨应用时间-温度阈值控制肝脏LITT的可行性。方法:16只实验兔,分成2组,均在介入性MRI引导下行LITT。组1和组2分别加热到60℃和时间-温度阈值。测量光导纤维尖端至测温针尖的距离(D1),以及光导纤维尖端至凝固性坏死最外缘的距离(... 详细信息

目的:探讨应用时间-温度阈值控制肝脏LITT的可行性。方法:16只实验兔,分成2组,均在介入性MRI引导下行LITT。组1和组2分别加热到60℃和时间-温度阈值。测量光导纤维尖端至测温针尖的距离(D1),以及光导纤维尖端至凝固性坏死最外缘的距离(D2)。结果:阈值温度54℃最为多见。组1D1与D2的差异有显著性统计学意义。组1达到时间-温度阈值平均节约时间(或能量)26.63%。结论:时间-温度阈值控制肝脏LITT能完全消融肝组织,节约消融时间和能量,减少正常组织损伤。

关键词：肝脏磁共振成像时间-温度阈值消融