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MoS_(2)nanosheets and bulk materials altered lipid profiles in 3D Caco-2 spheroids

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Chinese Chemical Letters 2022年第1期33卷 293-297页

作者： Min Xie Chaobo Huang yongqi liang Shuang Li Liping Sheng Yi Cao National Local Joint Engineering Laboratory for New Petro-chemical Materials and Fine Utilization of Resources College of Chemistry and Chemical EngineeringHunan Normal UniversityChangsha 410081China College of Chemical Engineering Nanjing Forestry University(NFU)Nanjing 210037China Key Laboratory of Environment-Friendly Chemistry and Applications of Ministry Education Laboratory of BiochemistryCollege of ChemistryXiangtan UniversityXiangtan 411105China Hunan Province Key Laboratory of Typical Environmental Pollution and Health Hazards School of Public HealthUniversity of South ChinaHengyang 421001China

MoS_(2)nanosheets(NSs)are novel 2D nanomaterials(NMs)with potential uses in many areas,and therefore oral exposure route to MoS_(2)NSs is ***,MoS_(2)NSs are considered as biocompatible NMs,but there is lacking of systemic investigations to study the interactions of MoS_(2)NSs with intestinal *** this study,we exposed the 3D Caco-2 spheroids to MoS_(2)NSs or MoS_(2)powders(denoted as MoS_(2)-bulk),and investigated the potential adverse effects of MoS_(2)-materials based on transcriptomics and lipidomics *** expected,both MoS_(2)NSs and MoS_(2)-bulk were dose-dependently internalized into 3D Caco-2 spheroids but did not induce cytotoxicity,membrane disruption or decrease of ***,the Gene Ontology(GO)and Kyoto Encyclopedia of Gene and Genomes(KEGG)analysis indicated that nutrient absorption and metabolism was *** of the most significantly decreased KEGG pathways is fat digestion and absorption(map04975),and Western blotting analysis further showed that fatty acid binding protein 1 and apolipoprotein A1,key proteins involved in fat digestion and absorption,were down-regulated by MoS_(2)NSs or MoS_(2)-*** addition,BODIPY 493/503 staining suggested that exposure to MoS_(2)NSs and MoS_(2)-bulk decreased lipid levels in the ***,lipidomics data indicated that MoS_(2)materials only decreased 8 lipid classes,including lysophosphatidylcholine,lysodimethylphosphatidylethanolamine,N-acylethanolamine,ceramide phosphoethanolamines,gangliosides,lysosphingomyelin and sulfatide,whereas most of the lipid classes were indeed *** addition,MoS_(2)NSs was more potent to decrease the lipid classes compared with MoS_(2)-***,the results from this study showed that MoS_(2)NSs and bulk materials were non-cytotoxic but altered lipid profiles in 3D Caco-2 spheroids.

关键词： MoS_(2)nanosheets(NSs) 3D Caco-2 spheroids Transcriptomics Lipidomics Fat digestion and absorption(map04975)

Antimony-Doping Induced Highly Efficient Warm-White Emission in Indium-Based Zero-Dimensional Perovskites

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CCS Chemistry 2020年第2期2卷 216-224页

作者： Xingyi Liu Xi Xu Ben Li yongqi liang Qi Li Hong Jiang Dongsheng Xu Beijing National Laboratory for Molecular Sciences State Key Laboratory for Structural Chemistry of Unstable and Stable SpeciesCollege of Chemistry and Molecular EngineeringPeking UniversityBeijing 100871China Department of Chemistry and Chemical Engineering Lanzhou UniversityLanzhou 730000China

Indium(In)-based halide perovskites are desirable for next-generation phosphors and emitting devices,due to their broad emission,nontoxicity,and oxidization avoidance ***,the In-based perovskites always exhibit low external photoluminescence quantum efficiency(PLQE)as a result of their weak light absorption near the corresponding excitation region,and thus,are limited in extended ***,we have developed an antimony(Sb)-doping strategy to improve the absorption ability of Cs2InCl5·H2O in the ultraviolet ***,we obtained a warm-light phosphor with ultrahigh external(internal)PLQE of 72.8%(86.7%).Typically,upon 1.5%Sb doping,the single-crystalline Cs2InCl5·H2O perovskite displayed a stronger warm-light emission at∼610 nm with a large Stokes shift of 295 nm and full width at half maximum(FWHM)of 164 *** functional theory(DFT)calculations revealed that the Sb-doping induced an impurity level in the bandgap,increasing the density of state(DOS),and promoted more carriers into the conduction band ***,external PLQE from 18%to 59%could be realized in other zero-dimensional In-based perovskites through the same doping strategy.

关键词： lead-free perovskite luminescence self-trapped exciton emission quantum efficiency antimony doping

Tracking Hypersonic Glide Vehicle Based on the MaRV Model with Multiple-model Approach

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Tracking Hypersonic Glide Vehicle Based on the MaRV Model wi...

第43届中国控制会议

作者： Liu Hao liang yongqi State Key Laboratory for Strength and Vibration of Mechanical Structures Xi'an Jiaotong University

In the research on hypersonic glide vehicle(HGV) tracking,the maneuvering reentry vehicle(Ma RV) model and multiple-model estimator have been widely ***,a systematic approach for model set design is ***,this paper analyzes MaRV model and its mode ***,the uniform model set is proposed,which is designed from an effective measurement approach for matching the uncertain model with the *** centered L2 discrepancy is applied to cover the uncertain mode of the target,and an in-depth analysis is ***,the mode space constructed based on the mode features of common aero vehicle(CAV) is *** interactive multiple model(IMM) estimator is employed for hybrid state ***,simulation results demonstrate that compared with Monte Carlo model sets,the proposed approach for MaRV model for HGV significantly improves the tracking accuracy.

关键词： Hypersonic Glide Vehicle Maneuvering Target Tracking Uniform Set Mode Space Interactive Multiple Model Estimator

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基于光度观测的空间目标姿态与角速度估计

光学学报 2017年第5期37卷 136-147页

作者：单斌梁勇奇李恒年西安交通大学机械结构强度与振动国家重点实验室陕西西安710049 西安卫星测控中心宇航动力学国家重点实验室陕西西安710043

基于目标形状反射以及太阳、地球和空间目标三者的运动关系建立了空间目标的光度量测模型,分析了姿态角、角速度和目标形状对光度观测数据的影响。建立了目标姿态角与角速度的运动学模型,实现了对姿态和角速度的联合估计,并探讨了算法... 详细信息

基于目标形状反射以及太阳、地球和空间目标三者的运动关系建立了空间目标的光度量测模型,分析了姿态角、角速度和目标形状对光度观测数据的影响。建立了目标姿态角与角速度的运动学模型,实现了对姿态和角速度的联合估计,并探讨了算法的自适应估计能力。仿真结果表明,该光度观测方案可实现未知姿态角与自旋角速度的估计,姿态角和角速度缓慢变化时算法具备自适应估计能力,但随着目标侧面数的增加,姿态和角速度估计误差增大且算法收敛速度变慢。

关键词：测量光度观测姿态估计角速度估计量测建模

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采用声发射技术检测钢桥疲劳裂纹

哈尔滨工程大学学报 2023年第4期44卷 649-656页

作者：鞠晓臣梁永奇赵欣欣杨江天中国铁道科学研究院集团有限公司铁道建筑研究所北京100081 北京交通大学机械与电子控制工程学院北京100044

为能对钢桥梁疲劳裂纹进行准确的状态识别,判断裂纹目前处于的状态,本文依据小波理论,采用声发射技术提出一种可进行疲劳裂纹全寿命跟踪检测的方法。设计了Q690q钢典型构造细节疲劳试验,使用声发射系统采集疲劳全过程的声发射信号,掌握... 详细信息

为能对钢桥梁疲劳裂纹进行准确的状态识别,判断裂纹目前处于的状态,本文依据小波理论,采用声发射技术提出一种可进行疲劳裂纹全寿命跟踪检测的方法。设计了Q690q钢典型构造细节疲劳试验,使用声发射系统采集疲劳全过程的声发射信号,掌握疲劳过程中信号变化规律。基于小波变换对疲劳裂纹声发射信号进行降噪处理,并通过波形分析法研究Q690q钢疲劳裂纹不同损伤阶段声发射信号的时域、频域、时频域特征,提取不同特征参数用于不同损伤阶段疲劳裂纹的状态识别。研究表明:本文所提方法成功对不同损伤阶段的疲劳裂纹进行检测,建立一种基于声发射的钢桥疲劳裂纹检监评估方法,可在裂纹发展早期予以识别,指导钢桥维修养护。

关键词： Q690q钢疲劳裂纹声发射小波降噪波形分析状态识别特征提取桥梁检测

大跨钢管混凝土拱桥吊杆破断动力响应与结构强健性分析

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武汉理工大学学报（交通科学与工程版） 2022年第2期46卷 275-280页

作者：邓育林汪浩梁永旗武汉理工大学交通与物流工程学院武汉430063 山西交通控股集团有限公司太原030006

基于ANSYS软件建立了某一大跨中承式钢管混凝土拱桥的空间有限元模型,分析拱桥吊杆破断后剩余结构的动力响应,及吊杆对称破断与不对称破断下各重要构件的易损性.结果表明:吊杆破断对邻近较短吊杆和桥面梁的冲击影响较大,而对主拱肋的影... 详细信息

基于ANSYS软件建立了某一大跨中承式钢管混凝土拱桥的空间有限元模型,分析拱桥吊杆破断后剩余结构的动力响应,及吊杆对称破断与不对称破断下各重要构件的易损性.结果表明:吊杆破断对邻近较短吊杆和桥面梁的冲击影响较大,而对主拱肋的影响较小,且短吊杆破断对剩余结构的影响明显高于长吊杆.吊杆对称破断对剩余吊杆、拱肋和横梁的影响较大,不对称破断对桥面板梁影响更为显著.边短吊杆破断对桥面板梁冲击效应较大,极易导致桥面板梁连续破坏.

关键词：钢管混凝土拱桥吊杆破断需求/能力比动力响应 ANSYS

Hybrid state estimation and model-set design of invariable-structure semi-ballistic reentry vehicle

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Science China(Information Sciences) 2011年第4期54卷 812-823页

作者： liang yongqi 1,2 & HAN ChongZhao 1 1 MOE KLINNS Lab,SKLMSE Lab,Institute of Integrated Automation,School of Electronics and Information Engineering,Xi’an Jiaotong University,Xi’an 710049,China 2 School of Aerospace,Xi’an Jiaotong University,Xi’an 710049,China 1. MOE KLINNS Lab SKLMSE Lab Institute of Integrated Automation School of Electronics and Information Engineering Xi’an Jiaotong University Xi’an 710049 China2. School of Aerospace Xi’an Jiaotong University Xi’an 710049 China

Multiple-model approach is one of the main streams for hybrid *** difficulty of this approach to estimate the hybrid state of the semi-ballistic reentry vehicle (SBRV) is model-set *** paper proposes a quasi-Monte Carlo model set that can ensure the estimator near-optimal in the sense of minimum mean square error (MMSE).The SBRV has a high nonlinearity and its mode is spanned by multiple parameters with known *** design methods and characteristics of the quasi-Monte Carlo model set are *** proposed model set has a higher accuracy than the model-set generated by the Monte Carlo *** theoretical analysis and simulation results show the effectiveness and reasonability of the newly designed model set.

关键词： semi-ballistic reentry vehicle hybrid estimation model-set design Monte Carlo method quasi-Monte Carlo method

动态问责系统:乡村生态治理中基层干部行动效能的提升机制

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中共天津市委党校学报 2022年第3期24卷 76-86页

作者：李华胤梁咏琪华中师范大学中国农村研究院中共麻城市委党校湖北武汉430079 华中师范大学中国农村研究院湖北武汉430079

问责是驱动基层干部实现有效治理的重要方式。通过强问责推进治理有效需要满足特定条件。行政问责、时间问责、高位问责和社会问责组成的系统性问责促使基层干部在规定时效内设置行为底线、提升治理效率、变革政策方向、回应民众诉求从... 详细信息

问责是驱动基层干部实现有效治理的重要方式。通过强问责推进治理有效需要满足特定条件。行政问责、时间问责、高位问责和社会问责组成的系统性问责促使基层干部在规定时效内设置行为底线、提升治理效率、变革政策方向、回应民众诉求从而推动行动效能逐步提高。动态性系统问责是促成基层干部行动效能提升的有效机制。问责的多维集成、力量聚合、对象同一、目标一致是动态问责系统建构及基层干部行为策略有效调整的基础条件,整体性、联系性、层序性和动态性是动态问责系统的作用特征,基层干部通过行为策略转换回应动态问责系统中的问责序列调整以提升生态治理效能。

关键词：动态问责系统行动策略有效基层干部农村生态治理

M²CS: A microwave measurement and control system for large-scale superconducting quantum processors

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CHINESE PHYSICS B 2024年第12期33卷 120309-120309页

作者： Zhang, Jiawei Sun, Xuandong Guo, Zechen Yuan, Yuefeng Zhang, Yubin Chu, Ji Huang, Wenhui liang, yongqi Qiu, Jiawei Sun, Daxiong Tao, Ziyu Zhang, Jiajian Guo, Weijie Jiang, Ji Linpeng, Xiayu Liu, Yang Ren, Wenhui Niu, Jingjing Zhong, Youpeng Yu, Dapeng Southern Univ Sci & Technol Shenzhen Inst Quantum Sci & Engn Shenzhen 518048 Peoples R China Int Quantum Acad Shenzhen 518048 Peoples R China Southern Univ Sci & Technol Guangdong Prov Key Lab Quantum Sci & Engn Shenzhen 518048 Peoples R China Southern Univ Sci & Technol Dept Phys Shenzhen 518048 Peoples R China Hefei Natl Lab Shenzhen Branch Shenzhen 518048 Peoples R China

As superconducting quantum computing continues to advance at an unprecedented pace, there is a compelling demand for the innovation of specialized electronic instruments that act as crucial conduits between quantum processors and host computers. Here, we introduce a microwave measurement and control system ((MCS)-C-2) dedicated to large-scale superconducting quantum processors. (MCS)-C-2 features a compact modular design that balances overall performance, scalability and flexibility. Electronic tests of (MCS)-C-2 show key metrics comparable to commercial instruments. Benchmark tests on transmon superconducting qubits further show qubit coherence and gate fidelities comparable to state-of-the-art results, confirming (MCS)-C-2's capability to meet the stringent requirements of quantum experiments running on intermediate-scale quantum processors. The compact and scalable nature of our design holds the potential to support over 1000 qubits after upgrade in stability and integration. The (MCS)-C-2 architecture may also be adopted to a wider range of scenarios, including other quantum computing platforms such as trapped ions and silicon quantum dots, as well as more traditional applications like microwave kinetic inductance detectors and phased array radar systems.

关键词： superconducting quantum computation superconducting qubit arbitrary waveform generator (AWG) data acquisition board (DAQ)