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Controllable two-dimensional Kerr and Raman–Kerr frequency combs in microbottle resonators with selectable dispersion

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Photonics Research 2021年第2期9卷 171-180页

作者： XUEYING JIN XIN XU HAORAN GAO KEYI WANG HAOJIE XIA liandong YU School of Instrument Science and Opto-electronics Engineering Hefei University of TechnologyHefei 230009China Department of Precision Machinery and Precision Instrumentation University of Science and Technology of ChinaHefei 230026China

We report a broadband two-dimensional(2 D) Kerr and Raman–Kerr frequency comb generation in a silica bottle resonator accounting for azimuthal and axial degrees of freedom and pioneer a method that allows for controlled and reversible switching between a four wave mixing(FWM) state and a stimulated Raman scattering state. The repetition rate of the Raman–Kerr comb is not an integer number of the free spectral range, which spans more than 242 nm with hundreds of teeth. We show that, experimentally and numerically, multiple 2 D comb regimes can be selectively accessed via dispersion engineering by exciting different orders of axial modes or modifying the curvature of the axial profile, involving cascaded FWM, Raman lasing, and Raman-assisted FWM. The effect of axial curvature on dispersion is associated with the axial mode number in bottle resonators. Our approach enables dispersion and spectral engineering flexibility in any resonator with localized axial modes.

关键词： resonator dispersion curvature

精益思维在广东省儿科住院医师规范化培训结业临床实践能力考核中的应用

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中国毕业后医学教育 2024年第2期8卷 102-106页

作者：樊慧峰何超许鹏高媛媛黄莉陈嘉慧左连东朱长艳广州医科大学附属妇女儿童医疗中心呼吸科广东广州510623 广州医科大学附属妇女儿童医疗中心科教与数据管理部广东广州510623 广州医科大学附属妇女儿童医疗中心内科部广东广州510623 广州医科大学附属妇女儿童医疗中心急诊科广东广州510623

目的探讨精益思维应用于广东省儿科住院医师规范化培训(简称住培)结业临床实践能力考核的效果分析。方法根据精益思维理念,结合广东省儿科住培结业临床实践能力考核要求进行规范管理。精益思维实施前后对考务工作人员进行问卷调查,并提... 详细信息

目的探讨精益思维应用于广东省儿科住院医师规范化培训(简称住培)结业临床实践能力考核的效果分析。方法根据精益思维理念,结合广东省儿科住培结业临床实践能力考核要求进行规范管理。精益思维实施前后对考务工作人员进行问卷调查,并提取2021年及2022年考官和考生满意度调查数据,评估精益思维实施效果。结果实施精益思维后,考务工作人员对精益思维了解程度明显提高(P<0.05);96.83%工作人员认为精益思维能有效提升工作效率,所有工作人员对精益思维的实施成效感到满意;精益思维实施后考官及考生对考务工作满意程度明显提高(P<0.05)。结论采用精益思维进行广东省儿科住培结业考核管理有利于提高工作人员效率和质量,保证考核过程的一致性,为组织大规模多地区统一的教学活动提供一定的借鉴意义。

关键词：精益思维结业考试儿科住院医师规范化培训临床技能考核

高精度自由空间光学时频基准传输技术研究进展

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激光与光电子学进展 2023年第3期60卷 125-133页

作者：于连栋朱家圣陆洋中国石油大学(华东)控制科学与工程学院山东青岛266555

自由空间时频基准传输是全球授时与同步、高速宽带通信、卫星编队飞行和空间物理参数监测等应用的关键技术,光钟技术的发展对光学时频基准传输精度提出了更高的要求。本文介绍了国内外自由空间光学时频基准传输技术的研究进展,重点介绍... 详细信息

自由空间时频基准传输是全球授时与同步、高速宽带通信、卫星编队飞行和空间物理参数监测等应用的关键技术,光钟技术的发展对光学时频基准传输精度提出了更高的要求。本文介绍了国内外自由空间光学时频基准传输技术的研究进展,重点介绍了不同研究机构基于光学频率梳开展的大气湍流相位噪声和空间噪声补偿方法,以满足高精度时间和频率基准的传输要求,最后对自由空间光学时频基准传输技术的应用进行了总结和展望。

关键词：仪器,测量与计量时频基准传输自由空间光学频率梳光学链路

Inhibition of H_(2)O_(2)-induced apoptosis of GC2-spg cells by functionalized selenium nanoparticles with lentinan through ROSmediated ERK/p53 signaling pathways

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BIOCELL 2023年第2期47卷 401-408页

作者： MIAOMIAO LI DANyang CHEN JUNYI KE RUILIN ZHENG JINGYAO SU ZILIN ZHENG JIEYI LUO HANRAN MAI FAN JIANG YANXIA QU XIAOQIONG GU BING ZHU YINGHUA LI liandong ZUO Department of Andrology Guangzhou Women and Children’s Medical CenterGuangzhou Medical UniversityGuangzhou510120China Center Laboratory Guangzhou Women and Children’s Medical CenterGuangzhou Medical UniversityGuangzhou510120China

AH_(2)O_(2)-induced oxidative stress injury cell model was established to investigate the antioxidant effect of nanoselenium on mouse spermatocyte lines and the regulation mechanism of the expression level and activity of seleniumcontaining antioxidant enzymes induced by oxidative stress.A safe and effective nano-drug system of functionalized selenium-containing nanoparticles(SeNPs)was developed with lentinan(LNT)(SeNPs@LNT).Mice spermatocyte line GC2-spg cells were treated with SeNPs@LNT(1,2,4,8,16,32μM)for 24-72 h to evaluate the cytotoxicity of selenium.GC2-spg cells were randomly divided into the following groups:control,hydrogen peroxide(H_(2)O_(2)),SeNPs@LNT,and H_(2)O_(2)+SeNPs@LNT groups.H_(2)O_(2)+SeNPs@LNT group was pretreated with SeNPs@LNT 4μM for 12 h,followed by H_(2)O_(2)600μM for 8 h.The cell viability decreased in the H_(2)O_(2) group and increased significantly in the SeNPs@LNT group.Compared with the H_(2)O_(2) group,the SeNPs@LNT+H_(2)O_(2) group exhibited obvious red fluorescence,indicating a higher level of mitochondrial membrane potential.The content of intracellular reactive oxygen species(ROS)in the SeNPs@LNT group reduced significantly,and the intensity of green fluorescence in the SeNPs@LNT+H_(2)O_(2) group decreased significantly compared with the H_(2)O_(2) group,indicating the inhibitory effect of SeNPs@LNT on the generation of ROS-induced oxidative stress.The activity of GPx and SOD increased significantly in the SeNPs@LNT group.The expression of p53 decreased significantly under the intervention of nano-selenium,and GPx1 expression increased.In the oxidative stress group,the expressions of DNA damage-related proteins and apoptosis-related proteins were higher than those in other groups.Thus,SeNPs@LNT can promote GC2-spg cell proliferation,improve GPx and SOD activities,remove intracellular ROS,and reduce mitochondrial damage and functional abnormalities caused by oxidative stress by regulating the ERK and p53 protein levels.SeNPs@LNT has good biological activity and antioxidant eff

关键词： Selenium nanoparticles Lentinan ROS Antioxidant

曲靖非相干散射雷达电离层E-F谷区电子密度日间变化特征初步分析

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电波科学学报 2022年第3期37卷 357-363页

作者：丁宗华代连东杨嵩苗建苏吴健中国电波传播研究所电波环境特性及模化技术重点实验室青岛266107 昆明电磁波环境国家野外科学观测研究站曲靖655500

电离层E-F谷区是电离层探测和研究的薄弱环节之一.文中利用曲靖非相干散射雷达日间120~200 km的电子密度观测数据,初步分析了曲靖地区电离层E-F谷区的变化特征.发现E-F谷区结构依赖于地方时与季节,相对于正午存在对称性,同时表现为两种... 详细信息

电离层E-F谷区是电离层探测和研究的薄弱环节之一.文中利用曲靖非相干散射雷达日间120~200 km的电子密度观测数据,初步分析了曲靖地区电离层E-F谷区的变化特征.发现E-F谷区结构依赖于地方时与季节,相对于正午存在对称性,同时表现为两种形态:一种在120~160 km存在明显谷区结构,谷底位于134~144 km;另一种的谷区很宽,谷底位于约130 m,在120~150 km电子密度随高度缓慢变化,160 km以上电子密度快速单调增加.一次耀斑爆发后129 km以下电子密度迅速增加,D层电子密度突然增强,而134 km以上变化不明显,可能与X射线增强有关.一次磁暴期间139~158 km电子密度变化不明显,177~196 km的电子密度出现了增强现象,可能与氧原子含量增加有关.

关键词：非相干散射雷达电离层电子密度谷区耀斑磁暴

基于BP-PSO的智能阀门定位器控制算法研究

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流体机械 2023年第5期51卷 49-54页

作者：高阳傅连东邓江洪湛从昌武汉科技大学机械自动化学院武汉430081 武汉科技大学冶金装备及其控制教育部重点实验室武汉430081

针对五步开关控制算法易超调以及控制参数取值具有近似性和不确定性等不足,提出了一种参数自整定和参数寻优的控制算法,并在最关键的脉冲调制控制环节运用了改进的BP神经网络算法和粒子群(PSO)算法来寻找最优阀门控制参数。搭建智能阀... 详细信息

针对五步开关控制算法易超调以及控制参数取值具有近似性和不确定性等不足,提出了一种参数自整定和参数寻优的控制算法,并在最关键的脉冲调制控制环节运用了改进的BP神经网络算法和粒子群(PSO)算法来寻找最优阀门控制参数。搭建智能阀门定位器实验平台,采用传统五步开关控制算法和本控制算法分别对阀门进行控制试验。结果表明,本控制算法相较于传统五步开关控制算法的适用性大大增强,避免了超调,缩短了响应时间,阀门控制精度达到0.03%,阀门开度稳定时间缩短至1 s以内。

关键词：智能阀门定位器参数自整定 BP神经网络优化 PSO粒子群算法

Methoxy poly(ethylene glycol)-b-poly(ethyl cyanoacrylate) copolymer nanoparticles as delivery vehicles for dexamethasone

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Chinese Science Bulletin 2009年第17期54卷 2918-2924页

作者： ZHAI YingLei DENG liandong LIN XiaoNa XIAO Li JIN FengMin DONG AnJie School of Chemical Engineering and Technology Tianjin University 'l-ianjin 300072 China

Methoxy poly(ethylene oxide)-b-poly(ethyl cyanoacrylate) (mPEG-b-PECA), amphiphilic block copolymer, was synthesized via oxyanion-initiated polymerization with a sodium alcoholate-terminated monomethoxy poly(ethylene glycol) as the macroinitiator. mPEG-b-PECA was characterized by GPC, 1H-NMR and FTIR. The results indicate that the structure of mPEG-b-PECA is well controlled with narrow molecular weight distribution. The dexamethasone (DXM)-loaded mPEG-b-PECA nanoparticles (NPs) were prepared by the nanoprecipitation technique and characterized by LPSA, 1H-NMR and TEM. The DXM-loaded mPEG-b-PECA NPs are of spherical shape with the size of less than 100 nm. The drug-loaded amount (DL) and encapsulation efficiency (EE) of DXM-loaded NPs were investigated by HPLC. The results show that DXM can be effectively incorporated into mPEG-b-PECA NPs, which provides a potential delivery system for DXM and other hydrophobic drugs.

关键词：甲氧基聚乙二醇两亲嵌段共聚物 MPEG 地塞米松纳米粒子运载工具丙烯酸酯氰基丙烯酸乙酯

类型小说的全球翻译——以犯罪小说、网络小说和科幻小说为例

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学术月刊 2023年第11期55卷 160-168页

作者：郭恋东冯若兮上海交通大学人文学院上海200030

当今全球超级畅销书几乎均为类型小说的杂糅,它们在翻译方面的快速流通是实现其全球畅销的关键。具体来看,北欧犯罪小说新势力和意大利犯罪小说的译本大增是外围/半外围语言类型小说全球崛起的典型,其成功的根本原因是在翻译中实现了既... 详细信息

当今全球超级畅销书几乎均为类型小说的杂糅,它们在翻译方面的快速流通是实现其全球畅销的关键。具体来看,北欧犯罪小说新势力和意大利犯罪小说的译本大增是外围/半外围语言类型小说全球崛起的典型,其成功的根本原因是在翻译中实现了既抵制又遵守全球市场机制的平衡。网络小说中粉丝的非专业翻译不仅是非专业译者在当地环境下获取国际流行文本的新策略,更是其重塑和定向全球文化流动的实际行动。全球科幻小说翻译的情况证明处于半边缘/边缘场域的科幻社群对全球科幻领域的重大贡献,科幻小说在全球历史上的真正创新时刻均是当其处于边缘/半边缘,正在发展成为半边缘/准核心的时刻,这一现象既是对莫莱蒂地理新空间产生虚构新空间观点的遵循,又是对其所强调的世界文学体系内不平等趋势日益加强观点的颠覆。总体而言,世界犯罪小说借由“全球本地化”概念对可译性问题的全新阐释,网络小说中非专业翻译对译者身份和翻译方法的挑战,全球科幻小说对翻译理论的叛逆,这些具体表现有力呈现出世界文学翻译的新趋向。

关键词：类型小说全球本地化犯罪小说网络小说科幻小说翻译理论

Parallel all-optical logic operations based on metasurface polarization optics

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Chinese Optics Letters 2023年第10期21卷 72-78页

作者：王婧汪文莉陆洋郝群于连栋 China University of Petroleum Qingdao 266580China Beijing Institute of Technology Beijing 100081China

We developed a general framework for parallel all-optical logic operations with independent phase control of arbitrary orthogonal polarization state enabled by a single-layer metasurface.A pair of orthogonal circular polarized bases are used as two input channels of the logic operator,and their four combinations perfectly match various binary input states.Correspondingly,distinct phase profiles are encoded into the metasurface,which enables parallel operation of the two logic gates by way of polarization switching.It allows for an efficient and compact way to implement multi-channel multiplexed logic gate operations with the capability of fast optical computing at the chip scale.

关键词： parallel all-optical logic operation metasurface polarization