检索结果-南通市图书馆

An epididymis-specific carboxyl esterase CES5A is required for sperm capacitation and male fertility in the rat

在线全文

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2015年第2期17卷 292-297,I0010,I0011页

作者： Yan-Fei Ru hai-Min Xue Zi-Mei Ni Dong Xia Yu-Chuan Zhou Yong-lian zhang Shanghai Key Laboratory of Molecular Andrology State Key Laboratory of Molecular Biology Institute of Biochemistry and Cell Biology Shanghai Institute for Biological Sciences Chinese Academy of Sciences Shanghai China University of Chinese Academy of Sciences Beijing China Institute of Animal Husbandry and Veterinary Sciences Shanghai Academy of Agricultural Sciences Shanghai China Shanghai Institute of Planned Parenthood Research Shanghai China.

Despite the fact that the phenomenon of capacitation was discovered over half century ago and much progress has been made in identifying sperm events involved in capacitation, few specific molecules of epididymal origin have been identified as being directly involved in this process in vivo. Previously, our group cloned and characterized a carboxyl esterase gene CesSa in the rat epididymis. The CES5A protein is mainly expressed in the corpus and cauda epididymidis and secreted into the corresponding lumens. Here, we report the function of CESSA in sperm maturation. By local injection of Lentivirus-mediated siRNA in the *** region of the rat epididymis, CesSa-knockdown animal models were created. These animals exhibited an inhibited sperm capacitation and a reduction in male fertility. These results suggest that CESSA plays an important role in sperm maturation and male fertility.

关键词： carboxylesterase CES5A epididymis male fertility sperm capacitation

Finite p-groups All of Whose Minimal Nonabelian Subgroups are Nonmetacyclic of Order p^3

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Mathematica Sinica,English Series 2019年第7期35卷 1179-1189页

作者： Qin hai zhang Department of Mathematics Shanxi Normal University

Assume p is an odd prime. We investigate finite p-groups all of whose minimal nonabelian subgroups are of order p^3. Let P1-groups denote the p-groups all of whose minimal nonabelian subgroups are nonme tacyclic of order p^3. In this paper, the P1-groups are classified, and as a by-product, we prove the Hughes' conjecture is true for the P1-groups.

关键词： Finite p-groups a minimal nonabelian subgroup the Hughes subgroup p-groups of maximal class

A Class of Non-degenerate Solvable Lie Algebras and Their Derivations

在线全文

学校读者我要写书评

暂无评论

Acta Mathematica Sinica,English Series 2008年第1期24卷 7-16页

作者： hai Shan zhang School of Mathematical Sciences Capital Normal University Beijing 10037 P. R. China

The author constructs a class of indecomposable non-degenerate solvable Lie Algebras corresponding to a Cartan matrix A over the field of complex numbers and we determine all their derivations.

关键词： non-degenerate solvable derivation finite-dimensional simple Lie algebra

Determination of Xenon in Air by a Pulse-discharge Helium Ionization Detector

在线全文

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2012年第5期28卷 814-817页

作者： CHEN Zhan-ying CHANG Yin-zhong LIU Shu-jiang zhang hai-tao WANG Shi-lian LI Qi CTBT Beijing National Data Centre&Beijing Radionuclide Laboratory Beijing 100085P.R.China Northwest Institute of Nuclear Technology Xi'an 710024P.R.China

A pulse-discharge helium ionization detector（Valco, PD-D3-I） was used to measure xenon concentration in air. The dependences of the detector relative response on various gas chromatograph parameters were investigated. Based on the well prepared gas connections for the detector system and optimized gas chromatography（GC） working conditions, the atmospheric xenon concentration could be measured by the cheap GC method with a detection level of 0.7×10-9（parts by volume）. Moreover, the xenon concentration in the ground level air around our laboratory was measured with the result of 0.085×10-6（parts by volume） and RSD of 0.91%.

关键词： Pulse-discharge helium ionization detector Xenon Gas chromatography(GC) Air analysis

Source-less density measurement using an adaptive neutron-induced gamma correction method

在线全文

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2023年第8期34卷 115-130页

作者： Qiong zhang Yi Ge Yu-lian Li University of Electronic Science and Technology of China Chengdu 610000China

The use of radioactive isotopes,such as Cs-137,to measure formation density is a common practice;however,it poses high risks such as environmental contamination from lost *** address these challenges,the use of pulsed neutron sources for density measurements,also known as“source-less density”,has emerged as a promising *** collecting gamma counts at different time gates according to the duty cycle of the pulsed sequence,the inelastic gamma component can be isolated to obtain more accurate density ***,the collection of gamma rays during the neutron burst-on period often contains a proportion of capture gamma rays,which can reduce the accuracy of density *** proportion can vary depending on the formation environment and neutron duty *** address these challenges,an adaptive capture gamma correction method was developed for density *** method distinguishes between“burst-on”and“burst-off”periods based on the gamma time spectra,and derives the capture ratio in the burst-on period by iteratively fitting the capture gamma time spectra,resulting in a more accurate net inelastic *** method identifies the end of the pulse by automatically calculating the differential,and fits the capture gamma time spectra using Gaussian process regression,which considers the differences in formation attenuation caused by different *** method was verified through simulations with errors of below 0.025 g/cm3,demonstrating its adaptability and feasibility for use in formation density ***,the proposed method has the potential to minimize the risks associated with radioactive isotopes and improve the accuracy of density measurements in various duty cycles and formation environments.

关键词： Neutron-induced gamma Adaptive correction Source-less density

The Reaction of Tanshinones with Amines

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2003年第6期14卷 557-560页

作者： Lin Kun AN Xian zhang BU hai Qiang WU Xin Dong GUO Lin MA lian Quan GU School of Chemistry and Chemical Engineering Sun Yat-Sen UniversityGuangzhou 510275

The reaction of cryptotanshinone and tanshinone IIA with several biogenic amine metabolites involved in the pathogenic pathways of HE were investigated and eight 1,2,3,4- tetrahydrophenanthrene derivatives, 2-6 and 8-... 详细信息

关键词： Cryptotanshinone tanshinone IIA biogenic amines.

Coexpression of MYC and BCL-2 predicts prognosis in primary gastrointestinal diffuse large B-cell lymphoma

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2015年第8期21卷 2433-2442页

作者： Bing Xia Le zhang Shan-Qi Guo Xiao-Wu Li Fu-lian Qu hai-Feng Zhao lian-Yu zhang Bao-Cun Sun James You Yi-Zhuo zhang Department of Hematology Tianjin Medical University Cancer Institute and Hospital National Clinical Research Center for Cancer Key Laboratory of Cancer Prevention and Therapy Ruijin Hospital and Medical School of Shanghai Jiao Tong University Department of Pathology Key Laboratory of Cancer Prevention and Therapy of Tianjin Tianjin Medical University Cancer Institute and Hospital Department of Hematopathology Division of Pathology/Lab Medicine The University of Texas MD Anderson Cancer Center Houston

AIM:To investigate whether MYC and BCL-2 coexpression has prognostic significance in primary gastrointestinal diffuse large B-cell lymphoma(PGI-DLBCL)patients,and explore its associations with patients’clinical ***:Fresh and paraffin-embedded tumor tissue samples from 60 PGI-DLBCL patients who had undergone surgery at the Tianjin Medical University Cancer Institute and Hospital from January 2005 to May 2010 were obtained,and 30 lymphoid tissue samples from reactive lymph nodes of age-and sexmatched patients represented control *** and diagnostic procedures were conducted according to the Lugano staging *** patients had been treated with three therapeutic modalities:surgery,chemotherapy,or *** of MYC and BCL-2 were detected at both protein and m RNA levels by immunohistochemistry and real-time ***:Positive expression levels of MYC and BCL-2proteins were detected in 35%and 45%of patients,***+/BCL-2+protein was present in30%of *** and BCL-2 protein levels were correlated with high MYC and BCL-2 m RNA expression,respectively(both P<0.05).We found that advancedstage disease(atⅡE-Ⅳ)was associated with MYC and BCL-2 coexpression levels(P<0.05).In addition,MYC+/BCL-2+patients had more difficulty in achieving complete remission than others(P<0.05).Presenceof MYC protein expression only affected overall survivaland progression-free survival(PFS)when BCL-2 proteinwas *** adverse prognostic impact ofMYC+/BCL-2+protein on PFS remained significant(P<0.05)even after adjusting for age,Lugano stage,international prognostic index,and BCL-2 proteinexpression in a multivariable ***:MYC+/BCL-2+patients have worsechemotherapy response and poorer prognosis thanpatients who only express one of the two proteins,suggesting that assessment of MYC and BCL-2 expressionby immunohistochemistry has clinical significance inpredicting clinical outcomes of PGI-DLBCL patients.

关键词： MYC BCL-2 Survival Primary gastrointestinal diffus

Existence of a-Cores for Games Without Compact Assumptions

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of the Operations Research Society of China 2024年第2期12卷 520-527页

作者： hai-Qun zhang School of International Economics and Trade Shanghai Lixin University of Accounting and Fin Shanghai201209China

Following the representation of Kajii(J Econ Theory 56:194-205,1992),we provide some existence theorems ofα-cores for games without ordered preferences and compact *** applications,we obtain some existence results of... 详细信息

关键词： α-Core Existence Preference Noncompactness

Bi-Frobenius Algebra Structures on Quantum Complete Intersections

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Mathematica Sinica,English Series 2024年第6期40卷 1481-1504页

作者： hai JIN Pu zhang School of Mathematical Sciences Shanghai Jiao Tong UniversityShanghai 200240P.R.China

This paper is to look for bi-Frobenius algebra structures on quantum complete intersections over field *** find a class of comultiplications,such that if√−1∈k,then a quantum complete intersection becomes a bi-Frobenius algebra with comultiplication of this form if and only if all the parameters qij=±***,it is proved that if√−1∈k then a quantum exterior algebra in two variables admits a bi-Frobenius algebra structure if and only if the parameter q=±√*** if−1/∈k,then the exterior algebra with two variables admits no bi-Frobenius algebra *** prove that the quantum complete intersections admit a bialgebra structure if and only if it admits a Hopf algebra structure,if and only if it is commutative,the characteristic of k is a prime p,and every ai a power of *** also provides a large class of examples of bi-Frobenius algebras which are not bialgebras(and hence not Hopf algebras).In commutative case,other two comultiplications on complete intersection rings are given,such that they admit non-isomorphic bi-Frobenius algebra structures.

关键词： Bi-Frobenius algebras coalgebras bialgebras Hopf algebras quantum complete intersections quantum exterior algebras