检索结果-南通市图书馆

维普期刊数据库博看期刊

Laparoscopic hepatic left lateral lobectomy combined with fiber choledochoscopic exploration of the common bile duct and traditional open operation

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2008年第7期14卷 1133-1136页

作者： Kun zhang Shao-Geng zhang Yi Jiang Peng-Fen Gao hai-Ying Xie Zhi-Hong Xie Department of Hepatobiliary Surgery Fuzhou General Hospital Fuzhou 350025 Fujian Province China Department of Ophthalmology Fuzhou General Hospital Fuzhou 350025 Fujian Province China

AIM: To investigate the possibilities and advantages of laparoscopic hepatic left lateral lobectomy combined with fiber choledochoscopic exploration of the common bile duct compaired with traditional open ***: Laparoscopic hepatic left lateral lobectomy combined with fiber choledochoscopic exploration of the common bile duct and traditional open operation were performed in two groups of patients who had gallstones in the left lobe of liver and in the common bile duct. The hospitalization time, hospitalization costs, operation time, operative complications and post-operative liver functions of the two groups of patients were ***: The operation time and post-operative liver functions of the two groups of patients had no significant differences, while the hospitalization time, hospitalization costs and operative complications of the laparoscopic hepatic left lateral lobectomy combined with fiber choledochoscopic exploration in the common bile duct group were significantly lower than those in the traditional open operation ***: For patients with gallstones in the left lobe of liver and in the common bile duct, laparoscopic hepatic left lateral lobectomy combined with fiber choledochoscopic exploration of the common bile duct can significantly shorten the hospitalization time, reduce the hospitalization costs and the post-operative complications,without prolonging the operation time and bringing about more liver function damages compared with traditional open operation. This kind of operation has more advantages than traditional open operation.

关键词： Laparoscopy Fiber choledochoscopy Hepatic Iobectomy Exploration of common bile duct

Generic attribute revocation systems for attribute-based encryption in cloud storage

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Information Technology & Electronic Engineering 2019年第6期20卷 773-786页

作者： Genlang CHEN Zhiqian XU Jia-jian zhang Guo-jun WANG hai JIANG Miao-qing HUANG Institute of Ningbo Technology Zhejiang University Ningbo 315100 China Ningbo Research Institute Zhejiang University Ningbo 315100 China Independent Scholar School of Computer Science and Technology Guangzhou University Guangzhou 510006 China Department of Computer Science Arkansas State University Jonesboro 72467 USA Department of Computer Science and Computer Engineering University of Arkansas Jonesboro 72467 USA

Attribute-based encryption(ABE) has been a preferred encryption technology to solve the problems of data protection and access control, especially when the cloud storage is provided by third-party service *** can put data access under control at each data item level. However, ABE schemes have practical limitations on dynamic attribute revocation. We propose a generic attribute revocation system for ABE with user privacy protection. The attribute revocation ABE(AR-ABE) system can work with any type of ABE scheme to dynamically revoke any number of attributes.

关键词： Attribute-based encryption Generic attribute revocation User privacy Cloud storage Access control

The effectiveness of the TAX 327 nomogram in predicting overall survival in Chinese patients with metastatic castration-resistant prostate cancer

在线全文

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2013年第5期15卷 679-684页

作者： Xiao-Jie Bian Yao Zhu Yi-Jun Shen Jin-You Wang Chun-Guang Ma hai-liang Zhan Bo Dai Shi-Lin zhang Xu-Dong Yao Ding-Wei Ye Department of Urology Fudan University Shanghai Cancer Center Shanghai 200032 China Department of Oncology Shanghai Medical College Fudan University Shanghai 200032 China

Based on the results of TAX 327, a nomogram was developed to predict the overall survival of metastatic castration-resistant prostate cancer （mCRPC） after first-line chemotherapy. The nomogram, however, has not been validated in an independent dataset, especially in a series out of clinical trials. Thus, the objective of the current study was to validate the TAX 327 nomogram in a community setting in China. A total of 146 patients with mCRPC who received first-line chemotherapy （docetaxel or mitoxantrone） were identified. Because clinical trials are limited in China's Mainland, those patients did not receive investigational treatment after the failure of first-line chemotherapy. The predicted overall survival rate was calculated from the TAX 327 nomogram. The validity of the model was assessed with discrimination, calibration and decision curve analysis. The median survival of the cohort was 21 months （docetaxel） and 19 months （mitoxantrone） at last follow-up. The predictive c-index of the TAX 327 nomogram was 0.66 （95% CI： 0.54-0.70）. The calibration plot demonstrated that the 2-year survival rate was underestimated by the nomogram. Decision curve analysis showed a net benefit of the nomogram at a threshold probability greater than 30%. In conclusion, the present validation study did not confirm the predictive value of the TAX 327 nomogram in a contemporary community series of men in China, and further studies with a large sample size to develop or validate nomograms for predicting survival and selecting therapies in advanced prostate cancer are necessary.

关键词： castration-resistant chemotherapy nomogram prostate cancer validation studies

基于SPEOS/CATIA的飞机驾驶舱眩光量化评估方法

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

系统工程理论与实践 2012年第1期32卷 219-224页

作者：张炜马智俞金海西北工业大学航空学院西安710072 中国商用飞机有限公司上海飞机设计研究院上海200232

针对飞机驾驶舱中的眩光评估问题,提出了一种基于SPEOS/CATIA的量化评估方法.该方法综合运用SPEOS/CATIA软件进行眩光场景的仿真,眩光源通过基于SPEOS/CATIA的二次开发自动获得,同时取得眩光源亮度、背景亮度、位置指数和光源立体角等参... 详细信息

针对飞机驾驶舱中的眩光评估问题,提出了一种基于SPEOS/CATIA的量化评估方法.该方法综合运用SPEOS/CATIA软件进行眩光场景的仿真,眩光源通过基于SPEOS/CATIA的二次开发自动获得,同时取得眩光源亮度、背景亮度、位置指数和光源立体角等参数,进而计算得到合适的眩光量化评估结果.最后,以某型飞机驾驶舱为例,进行了夜间和白天的眩光评估.计算结果表明,该方法能自动、快速地评估驾驶舱内眩光分布和量级.

关键词：飞机驾驶舱眩光量化评估

在线全文

学校读者我要写书评

暂无评论

青藏高原山地湖泊扩涨与山地关系分析

中国地质 2008年第1期35卷 144-149页

作者：胡忠贾玉连张海荣张彪魏灵江西师范大学地理环境学院惠州市惠阳区中山中学南京大学海岸与海岛开发教育部重点实验室江西南昌330026广东惠州516211江苏南京210008

基于1∶10万与1∶50万地形图,考察了青藏高原的山地湖泊及其流域的河流(水文)、雪线、冰川高度、各高度山地面积与湖泊面积之间的关系。高原湖泊的规模与流域山地(其高度,中、西部湖拔大于500～750m,东部大于250m)存在密切关系。揭示山... 详细信息

基于1∶10万与1∶50万地形图,考察了青藏高原的山地湖泊及其流域的河流(水文)、雪线、冰川高度、各高度山地面积与湖泊面积之间的关系。高原湖泊的规模与流域山地(其高度,中、西部湖拔大于500～750m,东部大于250m)存在密切关系。揭示山地降水是湖泊水的主要来源,其质(低温)与量是维持湖泊一定规模与稳定存在的主要因素。由于山地湖泊存在这种特殊的水文特点,因此,地质历史时期的暖湿期,高原山地湖泊比之低地、丘陵湖泊,扩涨规模可能更为显著。40～23kaB.P,高原山地湖泊异乎寻常地扩涨,可能是降水在暖期季风雨增加时,在山地区增高更甚,更多的低温水流贮湖泊造成的。

关键词：青藏高原山地湖泊山地降水湖泊扩涨

Sorption of ammonium and phosphate from aqueous solution by biochar derived from phytoremediation plants

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2013年第12期14卷 1152-1161页

作者： Zheng ZENG Song-da zhang Ting-qiang LI Feng-liang ZHAO Zhen-li HE He-ping ZHAO Xiao-e YANG hai-long WANG Jing ZHAO Muhammad Tariq RAFIQ Ministry of Education Key Laboratory of Environmental Remediation and Ecological Health College of Environmental and Resource Sciences Zhejiang University Ningbo Raw Water Group Co. Ltd. Indian River Research and Education Center Institute of Food and Agricultural Sciences University of Florida School of Environmental and Resource Sciences Zhejiang A&F University

The study on biochar derived from plant biomass for environmental applications is attracting more and more attention. Twelve sets of biochar were obtained by treating four phytoremediation plants, Salix rosthornii Seemen, Thalia dealbata, Vetiveria zizanioides, and Phragmites sp., sequentially through pyrolysis at 500 °C in a N2 environment, and under different temperatures(500, 600, and 700 °C) in a CO2 environment. The cation exchange capacity and specific surface area of biochar varied with both plant species and pyrolysis temperature. The magnesium(Mg) content of biochar derived from T. dealbata(TC) was obviously higher than that of the other plant biochars. This biochar also had the highest sorption capacity for phosphate and ammonium. In terms of biomass yields, adsorption capacity, and energy cost, T. dealbata biochar produced at 600 °C(TC600) is the most promising sorbent for removing contaminants(N and P) from aqueous solution. Therefore, T. dealbata appears to be the best candidate for phytoremediation application as its biomass can make a good biochar for environmental cleaning.

关键词： Biochar Nutrient removal Plant species Pyrolysis temperature Water quality

聚(苯胺-co-邻氨基酚)修饰玻碳电极的制备及其对抗坏血酸的电化学氧化

在线全文

学校读者我要写书评

暂无评论

分析化学 2007年第11期35卷 1575-1580页

作者：廉继英张雷上海师范大学生命与环境科学学院化学系上海师范大学生命与环境科学学院化学系上海200234

研究了苯胺（AN）与邻氨基酚（OAP）在玻碳电极表面的电化学共聚,由此制备了AN与OAP共聚物膜修饰的玻碳电极（PAN-OAP/GCE/CME）,并研究了该电极的电化学行为及其对抗坏血酸（AA）的电催化氧化。研究表明:AN与OAP的共聚速率随溶液中OAP... 详细信息

研究了苯胺（AN）与邻氨基酚（OAP）在玻碳电极表面的电化学共聚,由此制备了AN与OAP共聚物膜修饰的玻碳电极（PAN-OAP/GCE/CME）,并研究了该电极的电化学行为及其对抗坏血酸（AA）的电催化氧化。研究表明:AN与OAP的共聚速率随溶液中OAP浓度的增大而减小。当OAP与AN的浓度比>1∶10时,聚合行为相似;在其浓度比为1∶10时得到的共聚膜具有较好的电化学活性。由此可在0.1mol/L磷酸缓冲溶液（PBS,pH6.8）中对AA进行电催化氧化。在PAN-OAP/GCE/CME上其氧化峰电位位于0.21V,比在裸玻碳电极上（0.53V）降低了0.32V。该共聚物膜在中性溶液中显示出较好的电化学活性,为生物样本中AA的测定提供了条件。AA在修饰电极上的响应电流与其浓度在0.05;6.5mmol/L范围内呈线性关系,r=0.9998。采用计时电流法对AA催化氧化的扩散系数和催化速率常数进行了研究。

关键词：苯胺邻氨基酚抗坏血酸电化学共聚化学修饰电极

An-Luo-Hua-Xian Pill Improves the Regression of Liver Fibrosis in Chronic Hepatitis B Patients Treated with Entecavir

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Clinical and Translational Hepatology 2023年第2期11卷 304-313页

作者： Yi-Qi Liu Chi zhang Jia-Wen Li Li-Hua Cao Zhan-Qing zhang Wei-Feng Zhao Qing-Hua Shang Da-Zhi zhang An-Lin Ma Qing Xie Hong-lian Gui Guo zhang Ying-Xia Liu Jia Shang Shi-Bin Xie Jun Li Xu-Qing zhang Zhi-Qiang Zou Yu-Ping Chen Zong zhang Ming-Xiang zhang Jun Cheng Fu-Chun zhang Li-Hua Huang Jia-Bin Li Qing-Hua Meng hai-Bin Yu Yu-Qiang Mi Yan-Zhong Peng Zhi-Jin Wang Li-Ming Chen Fan-Ping Meng Wan-Hua Ren Lang Bai Yi-Lan Zeng Rong Fan Xian-Zhi Lou Wei-Feng liang Hui Liu Hui Zhuang Hong Zhao Gui-Qiang Wang Department of Infectious Disease Center for Liver DiseasePeking University First HospitalBeijingChina Department of Hepatology The Third Hospital of QinhuangdaoQinhuangdaoHebeiChina Department of Infectious Disease Shanghai Public Health Clinical CenterFudan UniversityShanghaiChina Department of Infectious Disease Xinxiang Medical University Affiliated Third HospitalXinxiangHenanChina No.88 Hospital of Chinese People’s Liberation Army(PLA) JinanShandongChina Department of Infectious Diseases The Second Affiliated Hospital of Chongqing Medical UniversityChongqingChina Department of Infectious Disease China-Japan Friendship HospitalBeijingChina Department of Infectious Diseases Ruijin HospitalSchool of MedicineShanghai Jiaotong UniversityShanghaiChina Department of Gastroenterology The People’s Hospital of Guangxi Zhuang Autonomous RegionNanningGuangxiChina Department of Infectious Diseases The Third People’s Hospital of ShenzhenShenzhenGuangdongChina Department of Infectious Diseases The People’s Hospital of Henan ProvinceZhengzhouHenanChina Department of Infectious Disease The Third Affiliated Hospital of Sun-Yat Sen UniversityGuangzhouGuangdongChina Department of Infectious Diseases Jiangsu Province HospitalThe First Affiliated Hospital of Nanjing Medical UniversityNanjingJiangsuChina Department of Infectious Diseases The Southwest Hospital of Army Medical UniversityChongqingChina Yantai Infectious Diseases Hospital YantaiShandongChina Department of Hepatology Baoding Infectious Diseases HospitalBaodingHebeiChina Department of Integrated Traditional Chinese Medicine(TCM)and Western Medicine Jinan Infectious Diseases HospitalShandong UniversityJinanShandongChina Department of Integrated TCM and Western Medicine in Hepatology The Sixth People’s Hospital of ShenyangShenyangLiaoningChina Beijing Ditan Hospital Capital Medical UniversityBeijingChina Department of Infectious Diseases Guangzhou Eighth People’s HospitalGuangzhou Medical UniversityGuangzhouGuangdon

Background and Aims:Chronic hepatitis B(CHB)can cause liver fibrosis and lead to cirrhosis and *** the effectiveness of antiviral therapy to reverse liver fibrosis is limited,We aimed to evaluate the effect of An-Luo-Hua-Xian pill(ALHX)on fibrosis regression in CHB patients treated with entecavir(ETV).Methods:Treatment-naïve patients with CHB were randomly treated with ETV alone or combined with ALHX(ETV+ALHX)between October 1,2013 and December 31,***,laboratory,and liver histology data before and after 78 weeks of treatment were *** Ishak fibrosis score(F)was used and fibrosis regression required a decrease in F of≥1 after ***:A total of 780 patients were enrolled,and 394 with a second liver biopsy after treatment were included in the per-protocol population,132 in ETV group and 262 in ETV+ALHX *** 78 weeks of treatment,the fibrosis regression rate in the ETV+ALHX group was significantly higher than that of the ETV group at baseline F≥3 patients:124/211(58.8%)vs.45/98(45.9%),p=*** percentage of patients with a decreased liver stiffness measurement(LSM)was higher in the ETV+ALHX group:156/211(73.9%)vs.62/98(63.%),p=*** regression analysis showed that ETV combined with ALHX was associated with fibrosis regression[odds ratio(OR)=1.94,p=0.018],and a family history of hepatocellular carcinoma was on the contrary.(OR=0.41,p=0.031).Conclusions:ETV combined with ALHX increased liver fibrosis regression in CHB patients.

关键词： Chronic hepatitis B Liver fibrosis Regression Randomized controlled trial

Uncarialins J-M from Uncaria rhynchophylla and Their Anti-depression Mechanism in Unpredictable Chronic Mild Stress-Induced Mice via Activating 5-HT_(1A) Receptor

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Chemistry 2021年第5期39卷 1331-1343页

作者： Zhen-Long Yu Rong Bai Jun-Jun Zhou Hui-lian Huang Wen-Yu Zhao Xiao-Kui Huo Ya-Hui Yang Zhi-Lin Luan Bao-Jing zhang Cheng-Peng Sun Xiao-Chi Ma Dalian Key Laboratory of Metabolic Target Characterization and Traditional Chinese Medicine Intervention National&Local Joint Engineering Research Center for Drug Development of Neurodegenerative DiseaseCollege of PharmacyCollege(Institute)of Integrative MedicineDalian Medical UniversityDalianLiaoning 116044China Department of Pharmacy Shanghai East HospitalTongji UniversityShanghai 200120China Laboratory of Modern Preparation of Traditional Chinese Medicine Ministry of EducationJiangxi University of Traditional Chinese MedicineNanchangJiangxi 330103China

Uncaria rhynchophylla has been widely used to treat central nervous system diseases for a long *** investigation of ***,eleven monoterpene indole alkaloids,including four new compounds uncarialins J-M(1-4)and seven known analogues(5-11),were isolated and *** structural characterization was conducted using HRESIMS,1D and 2D NMR,electronic circular dichroism(ECD)spectra,and quantum chemical *** 1,2,7,and 9-11 displayed significant ag-onistic effects towards 5-HT_(1A) receptor,and their EC_(50) values were 7.86,732,2.24,1.18,1.52,and 3.75μmol/L,***,in vivo experimental results fully revealed that hirsuteine(7)displayed a significant antidepression effect in unpredictable chronic mild stress(UCMS)-induced depression mice mainly via regulating 5-HT_(1A) signaling *** docking and site-directed amino acid mutation verified that amino acid residues Aspll6 and Asn386 were the binding sites of hirsuteine(7)with 5-HT_(1A) *** addition,pre-treatment of mice with WAY 100635 also blocked the anti-depression effect of hirsuteine(7),which further demonstrated that 5-HT_(1A) receptor was a potential target of hirsuteine(7)to effectively treat *** findings indicated the therapeutic material basis of *** and the anti-depression underlying mechanism of hirsuteine(7),and further provided the useful guidance for the development of hirsuteine(7)as a potential antidepressant candidate.

关键词： Monoterpene indole alkaloids Hirsuteine Depression 5-HT_(1A)receptor Site-directed amino acid mutation