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Effect of rapid rehabilitation nursing on improving clinical outcomes in postoperative patients with colorectal cancer

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World Journal of Gastrointestinal Surgery 2024年第7期16卷 2119-2134页

作者： Jing-Yan Song Jing Cao Jian Mao Jiang-lian wang Department of Nursing The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Oncology The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Information Center The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Oncology Yunyang County People's HospitalChongqing 400016China

BACKGROUND Surgical resection is the cornerstone treatment for colorectal *** rehabilitation care predicated on evidence-based medical theory aims to improve postoperative nursing care,subsequently reducing the physical and mental traumatic stress response and helping patients who undergo surgery recover *** To assess the effect of rapid rehabilitation care on clinical outcomes,including overall postoperative complications,anastomotic leaks,wound infections,and intestinal obstruction in patients with colorectal *** We searched the PubMed,Web of Science,Embase,Elsevier Science Direct,and Springer Link databases from January 1,2010,to January 1,2024,to screen eligible studies on rapid rehabilitation care among patients who underwent colorectal cancer *** were screened based on the inclusion and exclusion *** 5.4 software was used for statistical analysis of the *** Twelve studies were enrolled,which included 2420 *** results showed that rapid rehabilitation care decreased the incidence of overall postoperative complications(OR:0.44,95%CI:0.26–0.74,P=0.002),anastomotic leaks(OR:0.68,95%CI:0.41–1.12,P=0.13),wound infections(OR:0.45,95%CI:0.29–0.72,P=0.0007),and intestinal obstruction(OR:0.54,95%CI:0.34–0.86,P=0.01)compared to conventional *** trials and studies are needed to confirm these *** Rapid rehabilitation care decreased the occurrence of postoperative complications,anastomotic leaks,wound infections,and intestinal obstruction compared to conventional care in patients who underwent colorectal ***,promoting the application of rapid rehabilitation care in clinical practice cannot be overemphasized.

关键词： Rapid rehabilitation care Anastomotic leak Wound infection Intestinal obstruction Colorectal cancer

High-resolution neutronics model for ^(238)Pu production in high-flux reactors

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Nuclear Science and Techniques 2024年第5期35卷 226-236页

作者： Qing-Quan Pan Qing-Fei Zhao lian-Jie wang Bang-Yang Xia Yun Cai Jin-Biao Xiong Xiao-Jing Liu School of Nuclear Science and Engineering Shanghai Jiao Tong UniversityShanghai 200240China Science and Technology on Reactor System Design Technology Laboratory Nuclear Power Institute of ChinaChengdu 610200China

We proposed and compared three methods(filter burnup,single energy burnup,and burnup extremum analysis)to build a high-resolution neutronics model for 238Pu production in high-flux *** filter burnup and single energy burnup methods have no theoretical approximation and can achieve a spectrum resolution of up to~1 eV,thereby constructing the importance curve and yield curve of the full energy *** burnup extreme analysis method combines the importance and yield curves to consider the influence of irradiation time on production efficiency,thereby constructing extreme *** three curves,which quantify the transmutation rate of the nuclei in each energy region,are of physical significance because they have similar distributions.A high-resolution neutronics model for ^(238)Pu production was established based on these three curves,and its universality and feasibility were *** neutronics model can guide the neutron spectrum optimization and improve the yield of ^(238)Pu by up to 18.81%.The neutronics model revealed the law of nuclei transmutation in all energy regions with high spectrum resolution,thus providing theoretical support for high-flux reactor design and irradiation production of ^(238)Pu.

关键词： ^(238)Pu Neutronics model High-flux reactor Spectrum resolution Spectrum optimization

Impact of fluorine on crystal-melt separation in high-silica magma: Insights from muscovite in the Ramba leucogranite of Tethyan Himalaya

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Journal of Earth Science 2024年

作者： Li-Ran Chen wang-Chun Xu lian-Xun wang Hong-Fei Zhang Wuhan State Key Laboratory of Geological Processes and Mineral Resources and School of Earth Sciences China University of Geosciences

The process of crystal-melt separation in the high-silica magmatic mush is still a subject of debate. To explore the process， we conducted a detailed study of Late Miocene leucogranites (SiO2＞70 wt.%) in the Ramba Dome of the Tethyan Himalaya， focusing on the genesis and fluorine content of muscovite. The Ramba leucogranites consist of two-mica granite with minor garnet-bearing granite. Large and euhedral muscovites are found in both types of granite exhibiting different geochemical features. The muscovites from the two-mica granites exhibit lower F (mean value: ～0.41–0.43 wt.%)， FeO (mean value: ～1.75–1.81 wt.%)， but higher TiO2(mean value: ～0.61–0.73 wt.%) contents compared to those from the garnet-bearing granites (mean F value: ～0.72%; mean FeO value: 2.48 wt.%; mean TiO2value: ～0.23 wt.%). According to geochemical criteria， we categorized the muscovites from the two-mica granite as two groups: (1) crystallized from the early magma， and (2) formed from interstitial residual melt. In comparison， the muscovite from the garnet-bearing granite was likely crystallized from residual melt extracted from the same magmatic reservoir which underwent a higher degree of evolution. Accordingly， the two-mica granite represents the residual crystal mush consisting of early crystals crystallized from magma and trapped interstitial residual melt， while the garnet-bearing granite represents the aggregation of extracted residual melt. We examined the possibility of crystal-melt separation by estimating the variation of fluorine content and viscosity between the early magma and residual melt. Our results indicate a notable disparity in fluorine content between the residual melt (mean value: ～4364 ppm) and the early magma (mean value: ～2033 ppm). As a result， the estimated viscosity experiences a reduction from 106.52Pa s for the early magma to 105.87Pa s for the residual melt. The fluorine enrichment could have played a critical role in decreasing melt viscosity and initiating crys

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Comprehensive analysis of the gut microbiome and posttranslational modifications elucidates the route involved in microbiota-host interactions

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Zoological Research 2024年第1期45卷 95-107页

作者： Hai-Yang wang Lan-Xiang Liu Xue-Yi Chen Yang-Dong Zhang Wen-Xia Li Wen-Wen Li lian wang Xiao-Long Mo Hong Wei Ping Ji Peng Xie NHC Key Laboratory of Diagnosis and Treatment on Brain Functional Diseases First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China College of Stomatology and Affiliated Stomatological Hospital of Chongqing Medical University Chongqing 401147China Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences Chongqing 401147China Department of Neurology Yongchuan Hospital of Chongqing Medical UniversityChongqing 402160China Department of Pathology Faculty of Basic MedicineChongqing Medical UniversityChongqing 400016China Department of Neurology First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Yu-Yue Pathology Scientific Research Center Chongqing 401329China

The gut microbiome interacts with the host to maintain body homeostasis,with gut microbial dysbiosis implicated in many ***,the underlying mechanisms of gut microbe regulation of host behavior and brain functions remain *** study aimed to elucidate the influence of gut microbiota on brain functions via post-translational modification mechanisms in the presence or absence of bacteria without any *** conducted succinylome analysis of hippocampal proteins in germ-free(GF)and specific pathogen-free(SPF)mice and metagenomic analysis of feces from SPF *** results were integrated with previously reported hippocampal acetylome and phosphorylome data from the same batch of *** bioinformatics analyses revealed 584 succinylation sites on 455 proteins,including 54 up-regulated succinylation sites on 91 proteins and 99 down-regulated sites on 51 proteins in the GF mice compared to the SPF *** constructed a panoramic map of gut microbiota-regulated succinylation,acetylation,and phosphorylation,and identified cross-talk and relative independence between the different types of post-translational modifications in modulating complicated intracellular *** correlation analysis indicated that 13 taxa,predominantly belonging to the Bacteroidetes phylum,were correlated with the biological functions of post-translational *** correlations between these taxa and succinylation and negative correlations between these taxa and acetylation were identified in the modulation of intracellular *** study highlights the hippocampal physiological changes induced by the absence of gut microbiota,and proteomic quantification of succinylation,phosphorylation,and acetylation,contributing to our understanding of the role of the gut microbiome in brain function and behavioral phenotypes.

关键词： Gut microbiota Hippocampal protein Post-translational modifications Succinylation Acetylation Phosphorylation

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不同应力路径下层理煤体力学特性试验研究

岩土力学 2024年第2期45卷 385-395页

作者：范浩王磊王连国安徽理工大学深部煤矿采动响应与灾害防控国家重点实验室安徽淮南232001 中国矿业大学深部岩土力学与地下工程国家重点实验室江苏徐州221116

为探究不同应力路径下层理煤体力学特性和破坏特征,利用MTS816岩石力学试验系统对0°、30°、45°、60°和90°层理倾角煤样开展了常规三轴加载、增轴压卸围压和恒轴压卸围压应力路径下的力学试验,分析了应力路径和层理倾角对煤样强度... 详细信息

为探究不同应力路径下层理煤体力学特性和破坏特征,利用MTS816岩石力学试验系统对0°、30°、45°、60°和90°层理倾角煤样开展了常规三轴加载、增轴压卸围压和恒轴压卸围压应力路径下的力学试验,分析了应力路径和层理倾角对煤样强度、变形及破坏特征的影响规律。研究结果表明:(1)常规三轴加载条件下煤样在达到峰值强度前,应力-应变曲线呈近线性关系,达到峰值强度后,应力-应变曲线迅速跌落;增轴压卸围压条件下,随着卸荷比的增加,轴向应变增量比呈线性增加趋势,而环向应变增量比和体积应变增量比呈低速增长-急剧增长-平稳增长的三阶段变化特征;恒轴压卸围压条件下,轴向应变增量比、环向应变增量比和体积应变增量比均呈低速增长-急剧增长的两阶段变化特征。(2)随着层理倾角的增加,不同应力路径下煤样峰值强度和轴向峰值应变均呈先减小后增大的V型变化趋势,在0°时达到最大值,在60°时达到最小值。(3)随着卸荷比的增大,煤样变形模量先平缓后迅速劣化,泊松比先缓慢增加后呈指数形式增加,临界卸荷比随层理倾角的增大先增加后减小;当层理倾角相同时,增轴压卸围压条件下的临界卸荷比低于恒轴压卸围压。(4)常规三轴加载条件下煤样发生脆性剪切破坏,增轴压卸围压和恒轴压卸围压条件下煤样呈张拉-剪切混合破坏模式,当层理倾角为60°时,煤样主剪切破裂面角度与层理倾角几乎一致。

关键词：应力路径层理煤体力学特性破坏特征卸荷比

Clinical efficacy and safety of flexible ureteroscopy and percutaneous nephrolithotomy for large kidney stones:A retrospective comparative study

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World Journal of Clinical Cases 2024年第21期12卷 4483-4490页

作者： Qiu-lian wang Jun-Qiang Liu Juan Cao Jun Ding Department of Urology No.904 Hospital of Joint Logistic Support Force of PLAWuxi 214044Jiangsu ProvinceChina

BACKGROUND Renal stones ranging 20–40 mm are very common in *** no largesample clinical studies have confirmed the clinical efficacy and safety of this method,there is also a lack of comparative data with traditional *** To investigate the clinical efficacy of flexible ureteroscopy(FURS)and percutaneous nephrolithotomy(PCNL)by postoperative stone clearance and changes in soluble vascular cell adhesion molecule 1(sVCAM-1)and kidney injury molecule 1(KIM-1)levels in patients with large kidney stones(>2 cm in diameter).METHODS This single-center observational study was performed at a Chinese hospital between January 1,2021,and October 30,*** 250 enrolled patients were diagnosed with large kidney stones(>2 cm)and divided into a FURS group(n=145)and a PCNL group(n=105)by the surgical *** FURS group was treated with flexible ureteroscopy and the PCNL group was treated with percutaneous *** operation time,time to palinesthesia,intraoperative blood loss,drop in hemoglobin,length of hospital stay,stone clearance rate,and complications were recorded in the two *** and postoperative serum sVCAM-1 levels,erythrocyte sedimentation rate(ESR),urine KIM-1 levels,preoperative and postoperative pain visual analog scale(VAS)and Wisconsin Stone Quality of Life Questionnaire(WISQOL)scores were also *** All 250 eligible patients completed the *** were no significant differences in baseline characteristics between the two groups(P>0.05).The operation time in the FURS group was significantly greater than that in the PCNL *** time to ambulation,intraoperative blood loss,decrease in hemoglobin,and length of hospital stay were significantly lower in the FURS group than in the PCNL *** FURS group also had a significantly higher stone clearance rate and a lower incidence of postoperative *** was no significant difference in antibiotic use between the *** serum

关键词： Kidney stones Flexible ureteroscopy Percutaneous nephrolithotomy Clinical effective SCM-1 Erythrocyte sedimentation rate Kidney injury molecule 1

间接驱动相关条件下的大空间尺度对流受激拉曼侧向散射

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物理学报 2024年第10期73卷 256-269页

作者：曾嘉乐练昌旺季雨闫锐中国科学技术大学近代力学系合肥230026 上海交通大学IFSA协同创新中心上海200240

利用基于光线追踪和对流放大模型的模拟程序PHANTAM,对神光Ⅲ原型装置间接驱动相关条件下的大空间尺度受激拉曼散射进行了研究.模拟结果表明,在该参数条件下,真空腔和充气腔中均会发生较强的对流受激拉曼侧向散射过程.入射光的焦斑大小... 详细信息

利用基于光线追踪和对流放大模型的模拟程序PHANTAM,对神光Ⅲ原型装置间接驱动相关条件下的大空间尺度受激拉曼散射进行了研究.模拟结果表明,在该参数条件下,真空腔和充气腔中均会发生较强的对流受激拉曼侧向散射过程.入射光的焦斑大小是影响对流受激拉曼侧向散射的关键因素:在光强保持不变的条件下,真空腔和充气腔中受激拉曼侧向散射的对流增益会随焦斑增大而增大,而在功率保持不变的条件下,会随焦斑增大而减小.因此改变焦斑尺寸是调控受激拉曼侧向散射对流增益的有效途径.

关键词：激光等离子体不稳定性受激拉曼侧向散射对流模光线追踪

基于多卷积神经网络融合的当归病虫害识别方法

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江苏农业学报 2024年第1期40卷 121-129页

作者：郭标琦王联国甘肃农业大学信息科学技术学院甘肃兰州730000

针对目前当归产业病虫害识别方法缺失、人工提取特征存在主观因素及卷积神经网络训练需要大量数据等不足,提出1种基于多卷积神经网络融合的当归病虫害识别方法。构建当归常见病虫害数据集;选择在当归病虫害数据集中表现性能最好的ResNe... 详细信息

针对目前当归产业病虫害识别方法缺失、人工提取特征存在主观因素及卷积神经网络训练需要大量数据等不足,提出1种基于多卷积神经网络融合的当归病虫害识别方法。构建当归常见病虫害数据集;选择在当归病虫害数据集中表现性能最好的ResNet50、InceptionNetV3、VGG19、DenseNet2014个网络作为模型融合的基学习器;使用XGBoost(极度梯度提升)算法作为元学习器,得到基于多卷积神经网络融合的当归病虫害识别模型。结果表明,该融合模型比单个卷积神经网络模型具有更高的识别准确率,并优于其他融合方法融合的模型,对当归病虫害识别的查准率、查全率、F 1值分别达到98.33%、97.14%、97.68%。本研究提出的基于XGBoost融合方法融合的模型实现了当归常见病虫害的精确分类,对常见病害的识别准确率达到98.33%,为当归产业提供了一种有效的病虫害识别方法。

关键词：当归病虫害分类卷积神经网络极度梯度提升(XGBoost)融合方法

丁烷氧化脱氢Ni-Zn双金属催化剂:氧移动性与催化性能

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高校化学工程学报 2024年第2期38卷 229-235页

作者：赵勤阳王炼王金玲程党国陈丰秋詹晓力浙江省化工高效制造技术重点实验室浙江大学化学工程与生物工程学院浙江杭州310058 浙江大学衢州研究院浙江衢州324000

针对丁烷氧化脱氢反应中NiO催化剂性能差的问题,提出采用溶胶凝胶法制备一系列Ni-Zn双金属催化剂,考察了不同Zn含量下催化丁烷氧化脱氢的性能。结合氢气程序升温还原(H2-TPR)、程序升温氧化还原(TPRO)及X射线光电子能谱(XPS)等表征手段... 详细信息

针对丁烷氧化脱氢反应中NiO催化剂性能差的问题,提出采用溶胶凝胶法制备一系列Ni-Zn双金属催化剂,考察了不同Zn含量下催化丁烷氧化脱氢的性能。结合氢气程序升温还原(H2-TPR)、程序升温氧化还原(TPRO)及X射线光电子能谱(XPS)等表征手段,研究了催化剂的氧化还原能力对催化性能的影响。结果表明,NiZn_(0.5)催化剂的性能最好。Zn元素的加入提高了催化剂的氧移动性,体现在催化剂氧容量增大及催化剂上晶格氧的补充能力增强。NiZn_(0.5)催化剂由于具有最大的氧容量和最高的氧补充速率,在反应过程中催化剂上的氧空位更容易被填补。此外,双组分催化剂改善了单一NiO易结焦的问题。

关键词：丁烷氧化脱氢氧容量氧移动性稳定性