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Predictive values of plasma TNFαand IL-8 for intracranial hemorrhage in patients with acute promyelocytic leukemia

Frontiers of Medicine 2022年第6期16卷 909-918页

作者： Fangyi Dong li Chen Chaoxian Zhao Xiaoyang li Yun Tan Huan Song Wen Jin Hongming Zhu Yunxiang Zhang Kai Xue Junmin li Kankan Wang Shanghai Institute of Hematology State Key Laboratory of Medical GenomicsNational Research Center for Translational Medicine at ShanghaiRuijin Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai200025China CNRS-lia Hematology and Cancer Sino-French Research Center for Life Sciences and GenomicsRuijin Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai200025China

In patients with acute promyelocytic leukemia(APL),intracranial hemorrhage(ICH),if not identified promptly,could be *** is the leading cause of failure of induction and early ***,biomarkers that could promptly predict severe complications are ***,cytokine differences between patients with APL with and without ICH were investigated to develop predictive models for this *** initial cytokine profiling using plasma samples from 39 patients and 18 healthy donors found a series of cytokines that were remarkedly different between patients with APL and healthy *** APL patients were subsequently divided into high and low white blood cell count *** showed that tumor necrosis factor a and interleukin 8(IL-8)were vital in distinguishing patients with APL who did or did not develop *** addition,verification in 81 patients with APL demonstrated that the two cytokines were positively correlated with the cumulative incidence of ***,in-vitro and in-vivo experimental evidence were provided to show that IL-8 influenced the migration of APL-derived NB4 cells and impaired the blood-brain barrier in PML/RARαpositive blast-transplanted FVB/NJ *** assessments may facilitate the early warning of ICH and reduce future mortality levels in APL.

关键词： acute promyelocytic leukemia intracranial hemorrhage cytokines biomarker

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“以人为贵”思想与景德镇里弄文化保护中矛盾的解决

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景德镇学院学报 2017年第5期32卷 120-124页

作者：刘立煌景德镇陶瓷大学外国语学院江西景德镇333000

目前景德镇正在对老城区的里弄开展大规模的环境整治。在整治过程中如何协调里弄开发与里弄文化保护之间的矛盾是一项值得研究的课题。中国传统富贵文化中的"以人为贵"思想可以为矛盾解决提供众多的智慧。本文旨在探索"以人为贵"思想的... 详细信息

目前景德镇正在对老城区的里弄开展大规模的环境整治。在整治过程中如何协调里弄开发与里弄文化保护之间的矛盾是一项值得研究的课题。中国传统富贵文化中的"以人为贵"思想可以为矛盾解决提供众多的智慧。本文旨在探索"以人为贵"思想的内涵及其对景德镇里弄文化保护的作用,研究其发挥作用的途径。

关键词： “以人为贵” 里弄文化文化保护指引作用

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关于电力市场化体制改革的探讨

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广东水利电力职业技术学院学报 2008年第3期6卷 43-46页

作者：廖丽平广东水利电力职业技术学院广东广州510635

电力市场体制改革必然对电网企业的发展产生深远的影响。对此,以国家电力体制改革最终方向是输配分开为背景,分析当前电力市场体制改革中存在的各种问题及障碍,提出电力市场化改革步骤及输配分开实施的建议。

关键词：电力体制电力市场化体制改革

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Rollback reconstruction for TDC enhanced perfusion imaging

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Nuclear Science and Techniques 2021年第8期32卷 23-33页

作者： Jia-Shun liu Yi-Kun Zhang Hui Tang li-Bo Zhang Ben-Qiang Yang Ying Yan li-Min Luo Yang Chen Laboratory of Image Science and Technology Southeast UniversityNanjing 210096China Department of Radiology General Hospital of the Northern Theater of the Chinese People’s Liberation ArmyShenyang 110016China Department of Radiotherapy General Hospital of the Northern Theater of the Chinese People’s Liberation ArmyShenyang 110016China Centre de Recherche en Information Biomedicale SinoFrancais(lia CRIBs) 35000 RennesFrance

Tomographic perfusion imaging is a significant imaging modality for stroke ***,the low rotational speed of the C-arm(6–8 s per circle)is a challenge for applying perfusion imaging in C-arm cone beam computed tomography(CBCT).Traditional reconstruction methods cannot remove the artifacts caused by the slow rotational speed or acquire enough sample points to restore the time density curve(TDC).This paper presents a dynamic rollback reconstruction method for *** proposed method can improve the temporal resolution by increasing the sample points used for calculating the *** with existing techniques,the algorithm allows slow-rotating scanners to be used for perfusion imaging *** the experiments,the proposed method was compared with other dynamic reconstruction algorithms based on standard reconstruction and the temporal interpolation *** presented algorithm could improve the temporal resolution without increasing the X-ray exposure time or contrast agent.

关键词： Rollback reconstruction CBCT Time resolution Time density curve

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Biogenic silica concentration as a marine primary productivity proxy in the Holsteinsborg Dyb, West Greenland, during the last millennium

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Acta Oceanologica Sinica 2020年第9期39卷 78-85页

作者： Longbin Sha Dongling li Yanguang liu Bin Wu Yanni Wu Karen Luise Knudsen Zhongqiao li Hao Xu Department of Geography and Spatial Information Techniques Ningbo UniversityNingbo 315211China Laboratory for Marine Geology Pilot National Laboratory for Marine Science and Technology(Qingdao)Qingdao 266237China State Key Laboratory of Estuarine and Coastal Research East China Normal UniversityShanghai 200062China Key Laboratory of Marine Sedimentology and Environmental Geology First Institute of OceanographyMinistry of Natural ResourcesQingdao 266061China Key Laboratory of Marine Ecosystem and Biogeochemistry Second Institute of OceanographyMinistry of Natural ResourcesHangzhou 310012China Centre for Past Climate Studies and Arctic Research Centre Department of GeoscienceAarhus UniversityAarhus C DK-8000Denmark

We analyzed the biogenic silica(BSi)content and produced a diatom-based summer sea-surface temperature(SST)reconstruction for sediment core GC4 from the Holsteinsborg Dyb,West *** aim was to reconstruct marine productivity and climatic fluctuations during the last *** BSi content and diatom abundance suggest relatively high marine productively during the interval of AD 1000–1400,corresponding in time to the Medieval Warm Period(MWP).The summer SST reconstruction indicates relatively warm conditions during AD 900–1100,followed by cooling after AD *** extended cooling period during AD 1400–1900 is characterized by prolonged low in reconstructed SST and high sea-ice *** BSi values fluctuated during this period,suggesting varying marine productivity during the little Ice Age(lia).There is no significant correlation between the BSi content and SST during the last millennium,suggesting that the summer SST has little influence on marine productively in the Holsteinsborg Dyb.A good correspondence between the BSi content and the element Ti counts in core GC4 suggests that silicate-rich meltwater from the Greenland ice sheet was likely responsible for changes in marine productively in the Holsteinsborg Dyb.

关键词： biogenic silica marine productivity sea-surface temperature sea-ice concentration

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杀菌剂在莲瓣兰原生地萌发胚培养中的应用

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北方园艺 2011年第3期 148-150页

作者：李海峰赵志莲胡侃李明大理学院药学院云南大理671000 云南省大理农业学校云南大理671003

以莲瓣兰杂交种子原生地播种萌发突破种皮后的胚为外植体,研究了培养基中添加不同种类、不同浓度的杀菌剂对胚培养过程中真菌污染的控制作用。结果表明:培养基中添加培福朗、苯菌灵和代森锰锌能有效控制莲瓣兰杂交种子原生地萌发突破种... 详细信息

以莲瓣兰杂交种子原生地播种萌发突破种皮后的胚为外植体,研究了培养基中添加不同种类、不同浓度的杀菌剂对胚培养过程中真菌污染的控制作用。结果表明:培养基中添加培福朗、苯菌灵和代森锰锌能有效控制莲瓣兰杂交种子原生地萌发突破种皮后的胚培养过程中的真菌污染,胚污染率可以控制在10.0%以内,培养基中添加培福朗时胚成活率显著高于添加苯菌灵和代森锰锌,胚成活率高达92.4%;培养基中培福朗浓度在0.5～1.0mg/L范围内时胚污染率能够控制在9.0%以内,胚成活率超过92.3%,不仅能有效控制莲瓣兰杂交种子原生地萌发突破种皮后的胚培养过程中真菌污染,还能促进胚生长发育转绿成根状茎。

关键词：莲瓣兰胚培养杀菌剂真菌污染

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Cortical Network Localization of Vertigo

Cortical Network Localization of Vertigo

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第七届CAAE脑电图与神经电生理大会

作者： Yanran lia Jialin Dua Di Wangb Di Wu Xueyuan Wang Cuiping Xu Huaqiang Zhang Muyang li Tao Yu Yuping Wang liankun Ren Xuanwu Hospital Capital Medical University School of Medicine and Engineering Beihang University

Vertigo that means the illusion of movement of either the body or the surroundings is one of most common neurological *** contrast to the better understanding of the fundamental pathophysiological process on subtentor...

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IPACK阻滞与lia在膝关节矫形术的应用效果比较

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黑龙江医学 2024年第9期48卷 1061-1063页

作者：董星李欣赵克非保定市第一中心医院麻醉科河北保定071000

目的:比较腘动脉与膝关节后囊间隙(IPACK)阻滞与关节周围局部浸润镇痛(lia)在膝关节矫形术后镇痛中的效果。方法:招募60例膝关节矫形术患者,随机分为IPACK阻滞组(I组)和lia组(L组)。I组行IPACK阻滞,L组行lia。记录疼痛评分、满意度评分... 详细信息

目的:比较腘动脉与膝关节后囊间隙(IPACK)阻滞与关节周围局部浸润镇痛(lia)在膝关节矫形术后镇痛中的效果。方法:招募60例膝关节矫形术患者,随机分为IPACK阻滞组(I组)和lia组(L组)。I组行IPACK阻滞,L组行lia。记录疼痛评分、满意度评分、主动屈膝最大角度、步行距离、镇痛补救率和不良事件发生情况。结果:与L组比较,8h(T2)时点I组静态疼痛评分降低,差异有统计学意义(Z=-2.171,Plia更适合于膝关节矫形术后镇痛。

关键词：腘动脉与膝关节后囊间隙阻滞关节周围局部浸润镇痛膝关节矫形术

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炮弹壳体液态模锻模设计

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模具工业 2008年第2期34卷 61-63页

作者：熊洪淼李春王家宣李达南昌航空大学材料学院江西南昌330063

采用液态模锻工艺生产杯形、薄壁深筒形炮弹壳体,依据零件图设计了液态模锻工艺用锻件图、试验用模具,并生产出试验产品。经过试验产品分析,最终设计制造出生产用模具。模具结构简单、紧凑,工作平稳,生产的零件符合设计要求。

关键词：炮弹壳体液态模锻模具设计

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Changes in vegetation and moisture in the northern Tianshan of China over the past 450 years

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Frontiers of Earth Science 2020年第2期14卷 479-491页

作者： Weihe REN Yan ZHAO Quan li Jianhui CHEN Key Laboratory of Land Surface Pattern and Simulation Institute of Geographic Sciences and Natural Resources ResearchChinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China Key Laboratory of West China’s Environmental System(Ministry of Education) College of Earth and Environmental SciencesLanzhou UniversityLanzhou 730000China

Knowledge of historical changes in moisture within semi-arid and arid regions is the basis of climatic change predictions and strategies in response to long-term *** this study,a multiproxy peat record with highresolution from Sichanghu in the northern Tianshan was used to document the changes in vegetation and climate over the past 450 years in the arid Central *** pollen,grain size,and loss on ignition(LOI)records indicate that the productivity of local peat began to increase at^1730 *** vegetation in the Sichanghu area experienced several transitions,from temperate desert to dense desert,marsh meadow,and steppe desert *** climate in the study area was extremely dry during the early stages of the little Ice Age(lia)(before 1730 AD)and relatively wet during the late stages(1730–1880 AD).The inferred changes in the moisture conditions of the Sichanghu peatland since the lia may have been controlled by the extent of Arctic sea ice,the North Atlantic Oscillation,and the Siberian High via the connections of large-scale atmospheric circulations such as the Westerlies.

关键词： little Ice Age pollen vegetation change moisture condition Tianshan arid Central Asia

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