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Multipartite oil-flower/oil-bee mutualisms involving male-bee-pollinated orchids in tropical Asia

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National Science Review 2024年第5期11卷 105-107页

作者： Meng Zhang li-Bing Jia Susanne S.Renner Zhi-Xi Tian Xiao-An Wang Jiang-Yun Gao Yi-Bo Luo Antonio J.C.Aguiar Huan-li Xu Shuang-Quan Huang Institute of Evolution and Ecology School of Life Sciences Central China Normal University Department of Biology Washington University State Key Laboratory for Conservation and Utilization of Bio-resources in Yunnan Yunnan University State Key Laboratory of Systematic and Evolutionary Botany Institute of Botany Chinese Academy of Sciences Department of Zoology University of Brasília Department of Entomology College of Plant Protection China Agricultural University

Most animal-pollinated flowers offer nectar or pollen as a reward to their pollinators. A small fraction, however, have switched to other rewards, such as fatty oils offered in glandular hairs or just below the epidermis. This type of reward has evolved in some 150 genera in at least 11 families, including South American and African Orchidaceae [1,2]. Oiloffering flowers are exploited by a few hundred species of oil-collecting bees in temperate and tropical biomes on all continents except Antarctica [1,2]. Oil bees depend obligatorily on floral oil for cell lining and as larval food [3,4], which is why oil collecting usually is confined to female bees.

关键词： CTENOPLECTRINI HYMENOPTERA DENDROBIUM APIDAE

L-proline feeding for augmented freeze tolerance of Camponotus japonicus Mayr

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Science Bulletin 2019年第23期64卷 1795-1804页

作者： Mengjia Dou Yazhou li Ziqiao Sun Lei lia Wei Rao C4S Key Laboratory of Cryogenics Technical Institute of Physics and ChemistryChinese Academy of SciencesBeijing 100190China School of Engineering Science University of Chinese Academy of SciencesBeijing 100049China School of Energy and Power Engineering Beihang UniversityBeijing 100191China Beijing Engineering Research Center of Sustainable Energy and Buildings Beijing University of Civil Engineering and ArchitectureBeijing 100044China School of Future Technology University of Chinese Academy of SciencesBeijing 100049China Beijing Key Laboratory of Cryo-Biomedical Engineering Beijing 100190China

The successful cryopreservation of organs is a strong and widespread demand around the world but faces great challenges. The mechanisms of cold tolerance of organisms in nature inspirit researchers to find new solutions for these challenges. Especially, the thermal, mechanical, biological and biophysical changes during the regulation of freezing tolerance process should be studied and coordinated to improve the cryopreservation technique and quality of complex organs. Here the cold tolerance of the Japanese carpenter ants, Camponotus japonicus Mayr, was greatly improved by using optimal protocols and feeding on L-proline-augmented diets for 5 days. When cooling to -27.66 ℃, the survival rate of frozen ants increased from 37.50% ± 1.73% to 83.88% ± 3.67%. Profiling of metabolites identified the concentration of whole-body L-proline of ants increased from 1.78 to 4.64 ng g-1 after 5-day feeding. High Lproline level, together with a low rate of osmotically active water and osmotically inactive water facilitated the prevention of cryoinjury. More importantly, gene analysis showed that the expression of ribosome genes was significantly up-regulated and played an important role in manipulating freezing tolerance. To the best of our knowledge, this is the first study to link genetic variation to the enhancement of ants’ cold tolerance by feeding exogenous cryoprotective compound. It is worth noting that the findings provide the theoretical and technical foundation for the cryopreservation of more complex tissues,organs, and living organisms.

关键词： L-proline Cryopreservation Freeze tolerance Metabolomics Gene expression

含碳铁泥基催化剂活化H_(2)O_(2)处理亚甲基蓝废水

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工业水处理 2024年第2期44卷 125-132页

作者：王俩吴霜程小双梁澜李宁陈冠益侯立安天津大学环境科学与工程学院天津300350 中环保水务投资有限公司北京100082 天津商业大学机械工程学院天津300134

利用铁泥基催化剂构建类Fenton体系可实现污水厂废弃铁泥的资源化利用。热解温度可调控催化剂表面金属和非金属位点组成,影响其对过氧化氢(H_(2)O_(2))的活化效果。对不同热解温度(400~700℃)下制备的催化剂进行形貌、组成、结构和活性... 详细信息

利用铁泥基催化剂构建类Fenton体系可实现污水厂废弃铁泥的资源化利用。热解温度可调控催化剂表面金属和非金属位点组成,影响其对过氧化氢(H_(2)O_(2))的活化效果。对不同热解温度(400~700℃)下制备的催化剂进行形貌、组成、结构和活性等方面的测试。研究发现,700℃下制备的催化剂活化H_(2)O_(2),在100 min内对亚甲基蓝(MB)降解率达92.0%。当热解温度在400~700℃范围内增大时,催化剂比表面积和C含量均增大。机理探究表明,催化剂表面的Fe0、C==C/C—C和C==O活性位点对活化H_(2)O_(2)发挥重要作用,有利于促进亚甲基蓝降解。此外,铁泥基催化剂/H_(2)O_(2)体系中羟基自由基(·OH)和单线态氧(^(1)O_(2))是主要活性物种,超氧自由基(O_(2)^(·-))发挥作用较小。

关键词：废弃铁泥类Fenton 染料废水

Stability analysis of underground mine hard rock pillars via combination of finite difference methods,neural networks,and Monte Carlo simulation techniques

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Underground Space 2021年第4期6卷 379-395页

作者： Chuanqi lia Jian Zhou Danial Jahed Armaghani Xibing li School of Resources and Safety Engineering Central South UniversityChangsha 410083China Department of Civil Engineering Faculty of EngineeringUniversity of Malaya50603 Kuala LumpurMalaysia

Pillar stability is always evaluated using the safety factor(SF),which is defined as the ratio of pillar strength to pillar ***,most researchers have estimated pillar stress using the pillar shape ratio(w/h),uniaxial compressive strength(UCS)of the intact rock mass,and pillar depth(H).In this study,the geological strength index(GSI)of hard rock pillars was considered as a new variable for predictive *** index was developed by combining numerical simulation software(i.e.,FLAC3D)and a backpropagation neural network(BPNN).A hard rock pillar stability analysis,based on three methods including deterministic method,sensitivity analysis,and Monte Carlo simulation(MCS),was performed.A new formula was proposed to estimate the SF values based on the predicted stress,considering the GSI variable in the deterministic *** sensitivity analysis indicated that the variables impacting the SF from high to low are UCS,GSI,w/h,and *** this study,pillar stability was analyzed mainly using the GSI and MCS *** MCS results revealed that the GSI is also a major factor in pillar stability and has a greater effect on weak pillars than on strong ***,a pillar is more likely to be unstable when both the GSI and the UCS are *** study provides several references and procedures for improving the design of stable pillars considering the GSI as an important factor.

关键词： Hard rock pillar Numerical simulation Neural networks Safety factor Geological strength index Monte Carlo simulation

Mitotic inheritance of DNA methylation: more than just copy and paste

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Journal of Genetics and Genomics 2021年第1期48卷 1-13页

作者： Xuan Ming Bing Zhu Yingfeng lia National Laboratory of Biomacromolecules Institute of BiophysicsChinese Academy of SciencesBeijing 100101China College of life Sciences University of Chinese Academy of SciencesBeijing 100049China

Decades of investigation on DNA methylation have led to deeper insights into its metabolic mechanisms and biological *** understanding was fueled by the recent development of genome editing tools and our improved capacity for analyzing the global DNA methylome in mammalian *** review focuses on the maintenance of DNA methylation patterns during mitotic cell *** discuss the latest discoveries of the mechanisms for the inheritance of DNA methylation as a stable epigenetic *** also highlight recent evidence showing the rapid turnover of DNA methylation as a dynamic gene regulatory mechanism.A body of work has shown that altered DNA methylomes are common features in aging and *** discuss the potential links between methylation maintenance mechanisms and diseaseassociated methylation changes.

关键词： DNMT1 Mitotic DNA methylation inheritance Neighboring reinforcement model Aging-associated methylation changes

Large-scale pharmacogenomic studies and drug response prediction for personalized cancer medicine

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Journal of Genetics and Genomics 2021年第7期48卷 540-551页

作者： Fangyoumin Feng Bihan Shen Xiaoqin Mou Yixue lia Hong li CAS Key Laboratory of Computational Biology Shanghai Institute of Nutrition and HealthUniversity of Chinese Academy of SciencesChinese Academy of SciencesShanghai 200031China Hangzhou Institute for Advanced Study University of Chinese Academy of SciencesHangzhou 330106China

The response rate of most anti-cancer drugs is limited because of the high heterogeneity of cancer and the complex mechanism of drug *** treatment that stratifies patients into subgroups using molecular biomarkers is promising to improve clinical *** the accumulation of preclinical models and advances in computational approaches of drug response prediction,pharmacogenomics has made great success over the last 20 years and is increasingly used in the clinical practice of personalized cancer *** this article,we first summarize FDA-approved pharmacogenomic biomarkers and large-scale pharmacogenomic studies of preclinical cancer models such as patient-derived cell lines,organoids,and ***,we comprehensively review the recent developments of computational methods in drug response prediction,covering network,machine learning,and deep learning technologies and strategies to evaluate immunotherapy *** the end,we discuss challenges and propose possible solutions for further improvement.

关键词： Pharmacogenomics Personalized medicine Drug response Biomarkers Deep learning

Synthesis of 3-Methylthio-benzo[b]furans/Thiophenes via Intramolecular Cyclization of 2-Alkynylanisoles/Sulfides Mediated by DMSO/DMSO-d_(6) and SOCl_(2)

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Chinese Journal of Chemistry 2021年第4期39卷 887-895页

作者： Beibei Zhang Xiaoxian li Xuemin li Fengxia Sun Yunfei Du Tianjin Key Laboratory for Modern Drug Delivery&High-Efficiency School of Pharmaceutical Science and TechnologyTianjin UniversityTianjin300072 China College of Chemical and Pharmaceutical Engineering Hebei University of Science and TechnologyHebei Research Center of Pharmaceutical and Chemical EngineeringShijiazhuangHebei050018 China

Main observation and conclusion The reaction of 2-alkynylanisoles/sulfides with SOCl_(2) and DMSO was conducted to conveniently furnish the biologically interesting 3-(methylthio)-benzo[b]furans/thiophenes via intramolecular *** acts as a solvent as well as a sulfur source and can also be replaced with DMSO-d_(6),enabling the incorporation of the SCD3 moiety of DMSO-d_(6) to the 3-position of the heterocyclic frameworks.

关键词： 3-Methylthio-benzo[b]furans/Thiophenes 2-Alkynylanisoles/Sulfides DMSO/DMSO-d_(6)SOCl_(2) Interrupted pummerer process

Pt Complexes with High Molecular Weight Polyvinylmethyldimethylsiloxane ligands Supported on Diatomite for liquid-phase Hydrosilylation of 3, 3, 3-Trifluoropropene with Methyldichlorosilane

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Chinese Chemical Letters 2006年第6期17卷 803-806页

作者： Hong liu lia0 Huai Jun ZHU Feng Yi li College of Chemical and Energy South China University of Technology Guangzhou 510640 Chemistry Department of Nanchang University Nanchang 330047

Pt complexes with high molecular weight polyvinylmethyldimethylsiloxane （HMPVMS） ligands supported on diatomite as a catalyst for the hydrosilylation of 3, 3, 3-trifluoropropene and methyldichlorosilane. Results show that this catalyst displays good thermal stability, high activity and excellent recyclability, and it can be readily fabricated by a simple process.

关键词： Pt hydmsilylation high molecular weight polyvinylmethyldimethylsiloxane.

Fiber-shaped Supercapacitors:Advanced Strategies toward High-performances and Multi-functions

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Chinese Journal of Polymer Science 2020年第5期38卷 403-422,I0004页

作者： Jie Yang Xue-lian lia Jing-Wen Zhou Bin Wang Jian-li Cheng Institute of Chemical Materials China Academy of Engineering PhysicsMianyang 621900China Sichuan Research Center of New Materials Chengdu 610200China

Fiber-shaped supercapacitors(FSSCs)show great potential in portable and wearable electronics due to their unique advantages of high safety,environmental friendliness,high performances,outstanding flexibility and *** can directly act as the power sources or be easily integrated with other flexible devices to constitute self-powered and sustainable energy suppliers,providing excellent adaptability to irregular *** review mainly summarizes the recently reported works of FSSCs including preparation methods of various fiber electrodes,construction strategies of FSSCs and multi-functional device integrations,exploration of reaction mechanisms and strategies to improve the electrochemical performance and provision of suggestions on further designing and optimization of ***,it shares our perspectives on challenges and opportunities in this field,shedding light on the development of high-performance fiber-shaped supercapacitors with multifunctions.

关键词： Fiber-shaped supercapacitor Performance improvement Multi-function device Integrated electronics