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Minocycline in the eradication of Helicobacter pylori infection: A systematic review and meta-analysis

World Journal of Gastroenterology 2024年第17期30卷 2354-2368页

作者： Kai zhou Cai-ling li Hua Zhang Bao-Jun Suo Yu-Xin Zhang Xin-Lu Ren Yu-Xin Wang Chang-Min Mi ling-ling Ma li-ya zhou Xue-li Tian Zhi-Qiang Song Department of Gastroenterology Peking University Third HospitalBeijing 100191China

BACKGROUND Difficulty in obtaining tetracycline,increased adverse reactions,and relatively complicated medication methods have limited the clinical application of the classic bismuth quadruple ***,the search for new alternative drugs has become one of the research *** recent years,minocycline,as a semisynthetic tetracycline,has demonstrated good potential for eradicating Helicobacter pylori(***)infection,but the systematic evaluation of its role remains *** To explore the efficacy,safety,and compliance of minocycline in eradicating *** *** We comprehensively retrieved the electronic databases of PubMed,Embase,Web of Science,China National Knowledge Infrastructure,SinoMed,and Wanfang database as of October 30,2023,and finally included 22 research reports on *** eradication with minocycline-containing regimens as per the inclusion and exclusion *** eradication rates of *** were calculated using a fixed or a random effect model,and the heterogeneity and publication bias of the studies were *** The single-arm meta-analysis revealed that the minocycline-containing regimens achieved good overall *** eradication rates,reaching 82.3%[95%confidence interval(CI):79.7%-85.1%]in the intention-to-treat analysis and 90.0%(95%CI:87.7%-92.4%)in the per-protocol *** overall safety and compliance of the minocycline-containing regimens were good,demonstrating an overall incidence of adverse reactions of 36.5%(95%CI:31.5%-42.2%).Further by traditional meta-analysis,the results showed that the minocycline-containing regimens were not statistically different from other commonly used eradication regimens in eradication rate and incidence of adverse *** of the adverse reactions were mild to moderate and well-tolerated,and dizziness was relatively prominent in the minocycline-containing regimens(16%).CONCLUSION The minocycline-containing regimens demonstrated good efficacy,safety,and

关键词： Helicobacter pylori Minocycline Eradication Safety Resistance

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船舶通信导航技术及发展趋势研究

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科学与信息化 2024年第9期 135-137页

作者：李亚洲中海电信有限公司大连分公司辽宁大连 116001

船舶通信导航技术是船舶运输中不可或缺的一环,它涉及船舶的安全、效率与经济性.随着科技的不断发展,船舶通信导航技术也在不断提高和完善.因此,文章首先对船舶通信导航技术进行了深入探究,包含了船舶通信导航技术的特点、重要性;其次... 详细信息

船舶通信导航技术是船舶运输中不可或缺的一环,它涉及船舶的安全、效率与经济性.随着科技的不断发展,船舶通信导航技术也在不断提高和完善.因此,文章首先对船舶通信导航技术进行了深入探究,包含了船舶通信导航技术的特点、重要性;其次分析了北斗卫星在船舶航行技术中的应用,以及船舶通信技术的未来发展趋势,文章旨在鼓励航运企业积极引入新技术,提高海上运输的安全水平和商业效益.

关键词：船舶通信技术导航技术数字化

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RF power and I/Q imbalance calibration in B3G/4G MIMO-OFDM systems

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The Journal of China Universities of Posts and Telecommunications 2007年第2期14卷 89-93,124页

作者： li ya-zhuo zhou Ming-yu ZHANG Ping Wireless Technologies Innovation Institute Key Laboratory of Universal Wireless Communication Ministry of Education Beijing University of Posts and Telecommunications Beijing 100876 China

Radio frequency （RF） front-end nonidealities in multi-input and multi-output （MIMO） systems are more serious than in single-input and single-output systems and must be calibrated. According to the effects of RF power and in-phase/quadrature-phase （I/Q） imbalance, calibration methods for multi-input and multi-output-orthogonal frequency division multiplexing （MIMC-OFDM） systems in transmitter and interference in receiver are improved, respectively, in this article Furthermore, a calibration scheme including I/Q imbalance errors and amplitude variations is proposed and implemented in the B3G/4G time division duplex communication system. Simulation results show that the calibration algorithms are feasible, and the bit error rate （BER） performances for MIMO-OFDM systems are improved after calibrations.

关键词： calibration, B3G/4G MIMO-OFDM, front-end, I/Q imbalance

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An alternative aqueous synthetic route to preparing CdTe quantum dots with tunable photoluminescence

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Chinese Chemical Letters 2012年第3期23卷 359-362页

作者： Yi lin Wang Sheng yan liu li ya zhou School of Chemistry and Chemical Engineering Guangxi UniversityNanning 530004China

An aqueous synthetic route has been developed for the preparation of mercaptosuccinic acid（MSA）-capped CdTe quantum dots （QDs） using TeO_2 as tellurium source and sodium borohydride as *** size and the emission color of CdTe QDs can be tuned by varying the reflux *** obtained QDs were characterized by photoluminescence（PL） spectroscopy,X-ray powder diffraction（XRD） and high-resolution transmission electron microscopy（HRTEM）.The results show that the CdTe QDs were of zinc-blende crystal structure in a sphere-like shape.

关键词： Cadmium telluride Quantum dots Synthesis Photoluminescence

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Variant selection of nanocrystalline a phase in metastableβTB8 titanium alloy via electric pulse treatment

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稀有金属:英文版 2023年第8期42卷 2781-2794页

作者： Shan-Shan Wu ya yang Yuan-Biao Tan Song Xiang ya-li zhou Min Ma Fei Zhao Wei Shi Guizhou Key Laboratory of Materials Mechanical Behavior and Microstructure College of Materials and MetallurgyGuizhou UniversityGuiyang 550025China College of Materials Science and Engineering Hunan University of Science and TechnologyXiangtan 411201China

In this paper,the metastableβTB8 titanium alloy with nanocrystallineαphase is achieved by electric pulse *** morphology evolution and variant selection of nanocrystallineαphase in metastableβTB8titanium alloy were investigated by using scanning electron microscope(SEM),electron backscattered diffraction(EBSD)and transmission electron microscope(TEM)*** results indicated that the morphologies of the nanocrystallineαphase were mainly triangular clusters and needle-like at the pressure of 0 *** increasing pressure from 20 to 50 MPa,the volume fraction of needlelikeαphase decreased,and a large amount of V-shapedαphase formed in the interior ofβ*** on the EBSD data,the parentβphase was reconstructed by MTEX *** the interior of theβgrains,12 variants can form for the samples electric pulse treated at 0 and20 MPa,while only 3 and 6 variants can form for the samples electric pulse treated at 30 and 50 *** the grain boundary of theβgrains,one or more grain boundaryαvariants can be generated for the samples electric pulse treated at different pressures as long as one of the neighborβgrains follows the Burgers orientation relationship.

关键词： TB8 titanium alloy Parentβgrain reconstruction Morphology ofαphase Variant selection

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Luminescence properties of Cd Te QDs embedded in Zn_5(CO_3)_2(OH)_6 matrix

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Chinese Chemical Letters 2016年第12期27卷 1788-1792页

作者： Guo-Fang Wang An-Xiang Guan Chun-yan zhou Si-Yu Xia Qian Chen Xue-Ting Chen li-ya zhou School of Chemistry and Chemical Engineering Guangxi University

CdTe@Zn5（CO3）2（OH）G composites were synthesized by a hydrothermal method. CdTe@Zn5（CO3）2（OH）6 composite nanospheres were characterized via X-ray diffraction, scanning electron microscopy, energy- dispersive X-ray spectroscopy, and photoluminescence （PL）. The hydrothermal reaction time and the mole ratios of Zn/Te played important roles in the growth and fluorescence intensity of CdTe@Zn5（CO3）2（OH）6 composites. The composite powders showed peak PL at 578 nm at 1.6 times the intensity of powdered CdTe QDs. CdTe@Zn5（CO3）2（OH）6 exhibited a strong yellow fluorescence emission, and its preparation method was easy and economical. Therefore, CdTe@Zn5（CO3）2（OH）6 offers potential applications in biological markers and light-emitting diodes.

关键词： Quantum dots Fluorescent powder Basic zinc carbonate Hydrothermal light-emitting diodes

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Analyzing cytokines as biomarkers to evaluate severity of glaucoma

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International Journal of Ophthalmology(English edition) 2017年第6期10卷 925-930页

作者： yao Tong ya-li zhou yan Zheng Manas Biswal Pei-Quan Zhao Zhao-yang Wang Department of Ophthalmology Shanghai Ninth People＇s Hospital Shanghai Jiaotong University School of Medicine Shanghai 200011 China Department of Ophthalmology Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine Shanghai 200092 China Department of Ophthalmology Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine Chongming Branch Shanghai 202150 China Department of Molecular Genetics University of Florida Gainesville Florida 32610 USA

AIM： To analyze cytokines as biomarkers for evaluation of severity of glaucoma. METHODS： This was a prospective case-control study including 29 eyes with glaucoma. Besides, 28 eyes with senile cataract were used as control. Patients were classified into four groups： acute angle closure glaucoma （AACG）, chronic angle closure glaucoma （CACG）, primary open angle glaucoma （POAG） and senile cataract. Undiluted vitreous samples were collected, then vitreous concentrations of 9 types of cytokines were determined by cytometric bead assay system： y-interferon （IFNg）, interleukin （IL-10, IL-2, IL-4, IL-5, interferon-y-inducible protein （IP）-10, monocyte chemoattractant protein （MCP）-I, tumor necrosis factor （TNF） -Q, and vascular endothelial growth factor （VEGF）. We also recorded the intraocular pressure （lOP） of patients in each group and Pearson correlated analysis was performed to analysis the correlation between each type of cytokine with IOR RESULTS： Vitreous levels of IL-2, iL-5, MCP-1, TNF-a and IP-10 were significantly higher （P〈0.05） in AACG group. Patients with AACG, CACG and POAG have higher lOP than senile cataract, but we didn＇t find any significant correlation between lOP with any type of the cytokines. CONCLUSION： Inflammation and immune reaction have a strong link with the pathology of glaucoma especially AACG, Some cytokines may act as biomarkers to evaluate the severity of glaucoma, Anti-inflammatory treatments and controlling of lOP are necessary for the therapy of glaucoma.

关键词： glaucoma cytokines intraocular pressure

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Traumatic endophthalmitis and the outcome after vitrectomy in young children

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International Journal of Ophthalmology(English edition) 2020年第3期13卷 406-411页

作者： ya-li zhou Yi-Xiao Wang Teng-Teng yao Yuan yang Zhao-yang Wang Department of Ophthalmology Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghai 200011China Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology Shanghai 200011China

AIM:To explore the traumatic endophthalmitis in young children and the outcome of pars plana vitrectomy(PPV).METHODS:Twenty-two eyes of 22 cases of young children consecutive pediatric traumatic endophthalmitis treated and followed up between September 2014 and May 2018 were *** humor or vitreous samples were taken for bacterial culture and sensitivity *** antibiotics(norvancomycin and ceftazidime)injection,combined with 23-gauge PPV,were administered in 22 *** oil(SO;5000 centistoke)tamponade or perfluoropropane gas(C3F8)was used in all *** outcome measures were best-corrected visual acuity(BCVA)and retinal attachment,the ratio of penetrating injury,and the existence of intraocular foreign ***:The mean age of patients was 6.9±2.2(range,3-10)*** injured eyes suffered from penetrating ocular injury with retained intraocular foreign body in one *** culture was positive in only 2 *** mean follow-up time was 21.1±4.7(range,12-30)*** the primary PPV,intravitreal antibiotics was administrated in all eyes,SO in 18 eyes,and C3F8 in 4 *** secondary operation of SO removal and C3F8 endotamponade was performed in 16 eyes and a second SO endotamponade due to emulsification of the oil and retinal detachment(RD)was operated in 7 eyes underwent 3 to 11.5 mo after primary PPV.A third operation was done in 7 *** final intraocular pressure(IOP)was 8.9±1.8(range,6.9-11.4)mm *** final BCVAs were 20/200 or better in 5,counting fingers in 2,and light perception to hand movement in 8 ***(66.7%)had retinal injury exhibited worse BCVA(P=0.019,Fisher’s exact test).Eyes underwent SO tamponade exhibited worse final BCVA than that with C3F8 in the primary PPV(P=0.026,Fisher’s exact test).CONCLUSION:Traumatic endophthalmitis in children is generally more severe and associated with more complicated surgical *** patients have retinal injury need multiple operations and the final BCVA is poor

关键词： pediatric penetrating eye injury traumatic endophthalmitis pars plana vitrectomy

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In-situ SEM characterization of fracture mechanism of TiB/Ti-2Al-6Sn titanium matrix composites after electroshocking treatment

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Rare Metals 2024年第6期43卷 2805-2818页

作者： ya-ya Wu Jian zhou Guo-Lei Han yan Wen zhou Wang li-Qiang Wang Wei-Jie Lv Le-Chun Xie lin Hua Hubei Key Laboratory of Advanced Technology for Automotive Components Wuhan University of TechnologyWuhan 430070China Hubei Collaborative Innovation Center for Automotive Components Technology Wuhan 430070China Faculty of Materials and Manufacturing Beijing University of TechnologyBeijing 100124China State Key Laboratory of Metal Matrix Composites School of Materials Science and EngineeringShanghai Jiao Tong UniversityShanghai 200240China

In this article,in-situ scanning electron microscope characterization of the tensile properties of TiB/Ti-2Al-6Sn titanium matrix composite(TMC)was conducted before and after electroshocking treatment(EST).After EST,the tensile strength increased by 113.2 *** effect of EST on the tensile strength and fracture behavior of TiB was investigated using in-situ characterization of the fracture morphology and crack propagation path of the matrix and *** EST,TiB fracture introduced cracks that extended into the matrix,resulting in material *** EST,the refined TiB improved the bearing capacity of the matrix,thereby improving TMC ***,after EST,the cracks were introduced into the matrix,and resulting the fracture of matrix *** an increase in the external load,cracks in the matrix were observed to propagate to TiB,and the refined TiB was fractured,detached,and pulled out,resulting in the formation of *** the propagation path of the main crack after EST showed that the deflection angle of the main crack *** micro structure of the fracture surface indicated that the fracture of the matrix was plastic,whereas that of TiB was *** EST,the size and area of the dimples increased,confirming the increase in *** results revealed that the comprehensive mechanical properties of TiB/Ti-2Al-6Sn improved after ***,EST is an efficient method for tailoring the micro structures and mechanical properties of TMCs.

关键词： TiB/Ti-2Al-6Sn In-situ microstructure characterization Tensile properties Reinforcement Electroshocking treatment(EST)

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Helicobacter Pylori and Gastric Cancer： Clinical Aspects

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Chinese Medical Journal 2015年第22期128卷 3101-3105页

作者： Zhi-Qiang Song li-ya zhou Department of Gastroenterology Peking University Third Hospital Beijing 100191 China

Objective： Although Helicobacterpylori （H. pylori） is considered as the main etiological factor for gastric cancer, the strategy of screening and treating the oncogenic bacterium is still controversial. The objective was to evaluate the status and progress of the cognition about the relationship between 11. pylori infection and gastric cancer from a clinical aspect. Data Sourees： The data used in this review were mainly from the PubMed articles published in English from 1984 to 2015. Study Selection： Clinical research articles were selected mainly according to their level of relevance to this topic. Results： Gastric cancer is the fifth most common malignancy and the third leading cause of cancer deaths worldwide. The main etiological factor for gastric cancer is H. pylori infection. About 74.7-89.0% gastric cancer was related to H. pylori infection. Up to date, some regional gastric cancer prevention programs including the detection and treatment of H. pylori infection are under way. Current data obtained from the randomized controlled trials suggest that population-based H. pylori screening and treatment is feasible and cost-effective in preventing gastric cancer; however, a population-based H. pylori eradication campaign would potentially lead to bacterial resistance to the corresponding antibiotics, as well as a negative impact on the normal flora. Conclusions： The important questions of feasibility, program costs, appropriate target groups for intervention, and the potential harm of mass therapy with antibiotics must first be answered before implementing any large-scale program.

关键词： Clinical Eradication Gastric Cancer Helicobacterpylori Screening

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