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linearized waveform inversion for vertical transversely isotropic elastic media:Methodology and multi-parameter crosstalk analysis

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Petroleum Science 2024年第1期21卷 252-271页

作者： Ke Chen Lu liu li-nan xu Fei Hu Yuan Yang Jia-Hui Zuo Le-Le Zhang Yang Zhao National Key Laboratory of Petroleum Resources and Engineering Unconventional Petroleum Research InstituteChina University of Petroleum(Beijing)Beijing102249China Aramco Beijing Research Center Aramco AsiaBeijing100102China University of Lausanne LausanneCH-1015Switzerland Bureau of Geophysical Prospecting China National Petroleum CorporationZhuozhou 072750HebeiChina

Seismic migration and inversion are closely related techniques to portray subsurface images and identify hydrocarbon *** migration aims at obtaining structural images of subsurface geologic *** specifically,seismic migration estimates the reflectivity function(stacked average reflectivity or pre-stack angle-dependent reflectivity)from seismic reflection *** the other hand,seismic inversion quantitatively estimates the intrinsic rock properties of subsurface *** seismic inversion methods are applicable to detect hydrocarbon reservoirs that may exhibit lateral variations in the inverted *** there exist many differences,pre-stack seismic migration is similar with the first iteration of the general linearized seismic ***,seismic migration and inversion techniques assume an acoustic or isotropic elastic *** reservoirs such as shale and tight sand formation have notable anisotropic *** present a linearized waveform inversion(LWI)scheme for weakly anisotropic elastic media with vertical transversely isotropic(VTI)*** is based on two-way anisotropic elastic wave equation and simultaneously inverts for the localized perturbations(ΔVp_(0)/Vp_(0)/Vs_(0)/Vs_(0)/,Δ∈,Δδ)from the long-wavelength reference *** proposed VTI-elastic LWI is an iterative method that requires a forward and an adjoint operator acting on vectors in each *** derive the forward Born approximation operator by perturbation theory and adjoint operator via adjoint-state *** inversion has improved the quality of the images and reduces the multi-parameter crosstalk comparing with the adjoint-based *** have observed that the multi-parameter crosstalk problem is more prominent in the inversion images for Thomsen anisotropy ***,the Thomsen parameter is the most difficult to *** also analyze the multi-parameter crosstalk using scattering radiation patte

关键词： Elastic Anisotropy Least-squares imaging Waveform inversion Computational geophysics

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一种避障场景下的快速航迹恢复算法

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计算机科学 2024年第6期51卷 331-337页

作者：马英红李续楠董旭焦毅蔡伟郭有光西安电子科技大学通信工程学院西安710071 中国电子系统工程公司北京100000 西安邮电大学通信与信息工程学院西安710121 中国航天空气动力技术研究院北京100074

针对现有大部分避障场景中无人机避障算法未考虑无人机航迹恢复、少数航迹恢复算法恢复效果不佳的缺点,提出了一种避障场景下的无人机快速航迹恢复算法。综合考虑环境约束与无人机机动性能约束,通过旋转坐标系、判断无人机转弯方向、利... 详细信息

针对现有大部分避障场景中无人机避障算法未考虑无人机航迹恢复、少数航迹恢复算法恢复效果不佳的缺点,提出了一种避障场景下的无人机快速航迹恢复算法。综合考虑环境约束与无人机机动性能约束,通过旋转坐标系、判断无人机转弯方向、利用二分法对无人机整个避障及航迹恢复过程中的多个关键航迹点坐标进行计算,最终规划出一条安全高效的无人机避障及航迹恢复航迹。对比实验结果表明,快速航迹恢复算法规划出的避障及航迹恢复航迹更短,可以在距离障碍物更近的航迹点开始避障,避障及航迹恢复用时更短,航迹偏离度更小,整体航迹更优,对于绝大多数侦察场景中无人机需尽量保持沿离线航迹巡航的情况更加有利。

关键词：无人机航迹规划避障航迹恢复旋转坐标系

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Insights into restrictive cardiomyopathy from clinical and animal studies

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Journal of Geriatric Cardiology 2011年第3期8卷 168-183页

作者： Pierre-Yves Jean-Charles Yue-Jin li Chang-Long nan xu-Pei Huang Department of Biomedical Science College of Medicine Florida Atlantic University 777 Glades Road Boca Raton FL 33431 USA

Cardiomyopathies are diseases that primarily affect the myocardium, leading to serious cardiac dysfunction and heart failure. Out of the three major categories of cardiomyopathies （hypertrophic, dilated and restrictive）, restrictive cardiomyopathy （RCM） is less common and also the least studied. However, the prognosis for RCM is poor as some patients dying in their childhood. The molecular mechanisms behind the disease development and progression are not very clear and the treatment of RCM is very difficult and often ineffective. In this article, we reviewed the recent progress in RCM research from the clinical studies and the translational studies done on diseased transgenic animal models. This will help for a better understanding of the mechanisms underlying the etiology and development of RCM and for the design of better treatments for the disease.

关键词： etiology myocardial gene mutation restrictive cardiomyopathy transgenic mice

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Coupling interface constructions of hollow Co-Mo mixed multiple oxidation states heterostructure for high-performance aprotic li-O_(2) battery

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nano Research 2024年第5期17卷 4100-4107页

作者： Xingzi Zheng Mengwei Yuan Jingshen xu Zihan li Caiyun nan Genban Sun Beijing Key Laboratory of Energy Conversion and Storage Materials College of ChemistryBeijing Normal UniversityBeijing 100875China Center for Advanced Materials Research Beijing Normal UniversityZhuhai 519087China

Constructing interfaces in heterostructures is effective for modulating the electronic properties of *** hollow CoMoO_(4)-Co_(3)O_(4) heterostructure(HCMCH)was prepared as a bifunctional electrocatalyst for li-O_(2) *** different components in CoMoO_(4)-Co_(3)O_(4) heterostructure presented the efficient coupling and enhanced the electrocatalytic activity for aprotic oxygen reduction reaction(ORR)and oxygen evolution reaction(OER),in which it improved the obviously reduced overpotential of 300 mV(compared with the pure Ketjen black(KB)electrode),enhanced reversibility of 80%capacity retention after 6 full cycles and the superior cyclability of more than 200 cycles with an optimized *** battery performance of the HCMCH was not only associated with the unique hollow structure and rich active sites but also with coupling interface constructions synergetic effects attaching to the improving conductivity and optimized the discharge *** results suggested that this HCMCH electrocatalyst was a promising candidate for the li-O_(2) battery and it gave a novel insight for high performance electrocatalyst designing.

关键词： li-oxygen battery heterostructure electrocatalyst coupling interface

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Prediction of three-dimensional ocean temperature in the South China Sea based on time series gridded data and a dynamic spatiotemporal graph neural network

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Acta Oceanologica Sinica 2024年第7期43卷 26-39页

作者： Feng nan Zhuolin li Jie Yu Suixiang Shi Xinrong Wu lingyu xu Department of Computer Engineering and Science Shanghai UniversityShanghai 200444China Key Laboratory of Digital Ocean National Marine Data and Information ServiceTianjin 300171China

Ocean temperature is an important physical variable in marine ecosystems,and ocean temperature prediction is an important research objective in ocean-related ***,one of the commonly used methods for ocean temperature prediction is based on data-driven,but research on this method is mostly limited to the sea surface,with few studies on the prediction of internal ocean *** graph neural network-based methods usually use predefined graphs or learned static graphs,which cannot capture the dynamic associations among *** this study,we propose a novel dynamic spatiotemporal graph neural network(DSTGN)to predict threedimensional ocean temperature(3D-OT),which combines static graph learning and dynamic graph learning to automatically mine two unknown dependencies between sequences based on the original 3D-OT data without prior *** and spatial dependencies in the time series were then captured using temporal and graph *** also integrated dynamic graph learning,static graph learning,graph convolution,and temporal convolution into an end-to-end framework for 3D-OT prediction using time-series grid *** this study,we conducted prediction experiments using high-resolution 3D-OT from the Copernicus global ocean physical reanalysis,with data covering the vertical variation of temperature from the sea surface to 1000 m below the sea *** compared five mainstream models that are commonly used for ocean temperature prediction,and the results showed that the method achieved the best prediction results at all prediction scales.

关键词： dynamic associations three-dimensional ocean temperature prediction graph neural network time series gridded data

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linear paired electrolysis of furfural to furoic acid at both anode and cathode in a multiple redox mediated system

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Green Energy & Environment 2024年第1期9卷 104-113页

作者： Xinxin li linchuan Cong Haibo lin Fangbing liu Xiangxue Fu Hai-Chao xu nan lin State Key Laboratory of Inorganic Synthesis and Preparative Chemistry Jilin UniversityChangchun 130012JilinChina State Key Laboratory of Physical Chemistry of Solid Surfaces College of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005FujianChina

Implementing a new energy-saving electrochemical synthesis system with high commercial value is a strategy of the sustainable development for upgrading the bulk chemicals preparation technology in the ***,we report a multiple redox-mediated linear paired electrolysis system,combining the hydrogen peroxide mediated cathode process with the I2 mediated anode process,and realize the conversion of furfural to furoic acid in both side of the dividedﬂow cell *** reasonably controlling the cathode potential,the undesired water splitting reaction and furfural reduction side reactions are *** the galvanostatic electrolysis,the two-mediated electrode processes have good compatibility,which reduce the energy consumption by about 22%while improving the electronic efﬁciency by about 125%.This system provides a green electrochemical synthesis route with commercial prospects.

关键词： Multiple redox mediated system linear paired electrolysis Furfural Furoic acid

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Icariin plus curcumol enhances autophagy through the mTOR pathway and promotes cathepsin B-mediated pyroptosis of prostate cancer cells

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Asian Pacific Journal of Tropical Biomedicine 2024年第2期14卷 55-64页

作者： xu-Yun Wang Wen-Jing xu Bo-nan li Tian-Song Sun Wen Sheng Department of Andrology Beijing Hospital of Traditional Chinese MedicineCapital Medical UniversityBeijing100010China Department of Dermatology The First Affiliated Hospital of Hunan University of Chinese MedicineChangsha410021China School of Integrated Chinese and Western Medicine Hunan University of Chinese MedicineChangsha410208China Andrology Laboratory Hunan University of Chinese MedicineChangsha410208China School of Rehabilitation Medicine and Health Care Hunan University of MedicineHuaihua418000China School of Traditional Chinese Medicine Hunan University of MedicineHuaihua418000China

Objective:To examine the effect of icariin plus curcumol on prostate cancer cells PC3 and elucidate the underlying ***:We employed the Cell Counting Kit 8 assay and colony formation assay to assess cell viability and *** expression was analyzed using monodansylcadaverine *** and Western blot analyses were used to evaluate protein expressions related to autophagy,pyroptosis,and the mTOR *** damage was examined using the lactate dehydrogenase ***,cathepsin B and NLRP3 were detected by ***:Icariin plus curcumol led to a decrease in PC3 cell proliferation and an enhancement of *** levels of LC3-Ⅱ/LC3-Ⅰand beclin-1 were increased,while the levels of p62 and mTOR were decreased after treatment with icariin plus *** changes were reversed upon overexpression of ***,3-methyladenine resulted in a decrease in inflammatory cytokines,pyroptosis-related protein levels,and lactate dehydrogenase concentration,compared to the icariin plus curcumol *** cathepsin B reversed the regulatory effects of icariin plus ***:Icariin plus curcumol demonstrates great potential as a therapeutic agent for castration-resistant prostate cancer by enhancing autophagy via the mTOR pathway and promoting pyroptosis mediated by cathepsin *** findings provide valuable insights into the molecular mechanisms underlying the therapeutic potential of icariin and curcumol for prostate cancer treatment.

关键词： Icariin Curcumol Autophagy mTOR Cathepsin B Pyroptosis Prostate cancer

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Prediction of contact resistance of electrical contact wear using different machine learning algorithms

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Friction 2024年第6期12卷 1250-1271页

作者： Zhen-bing CAI Chun-lin li Lei YOU xu-dong CHEN li-ping HE Zhong-qing CAO Zhi-nan ZHANG Tribology Research Institute Southwest Jiaotong UniversityChengdu 610031China State Key Laboratory of Mechanical System and Vibration Shanghai Jiao Tong UniversityShanghai 200240China

H62 brass material is one of the important materials in the process of electrical energy transmission and signal transmission,and has excellent performance in all *** the wear behavior of electrical contact pairs is particularly complex when they are in service,we evaluated the effects of load,sliding velocity,displacement amplitude,current intensity,and surface roughness on the changes in contact *** learning(ML)algorithms were used to predict the electrical contact performance of different factors after wear to determine the correlation between different factors and contact *** forest(RF),support vector regression(SVR)and BP neural network(BPNN)algorithms were used to establish RF,SVR and BPNN models,respectively,and the experimental data were trained and *** was proved that BP neural network model could better predict the stable mean resistance of H62 brass alloy after *** analysis shows that the load and current have great influence on the predicted electrical contact *** wear behavior of electrical contacts is influenced by factors such as load,sliding speed,displacement amplitude,current intensity,and surface roughness during *** learning algorithms can predict the electrical contact performance after wear caused by these *** results indicate that an increase in load,current,and surface roughness leads to a decrease in stable mean resistance,while an increase in displacement amplitude and frequency results in an increase in stable mean resistance,leading to a decline in electrical contact *** reduce testing time and costs and quickly obtain the electrical contact performance of H62 brass alloy after wear caused by different factors,three algorithms(random forest(RF),support vector regression(SVR),and BP neural network(BPNN))were used to train and test experimental results,resulting in a machine learning model suitable for predicting the stable mean

关键词： electrical contact wear contact resistance machine learning(ML) neural network

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Perspective of Calcium Imaging Technology Applied to Acupuncture Research

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Chinese Journal of Integrative Medicine 2024年第1期30卷 3-9页

作者： li Sha liU Yun ZHANG nan li Wang xu Wen-jie xu Yi-qian CHEN Yi-yuan CUI Xiang ZHU Bing GAO Xin-yan Institute of Acupuncture and Moxibustion China Academy of Chinese Medical SciencesBeijing(100700)China

Acupuncture, a therapeutic treatment defined as the insertion of needles into the body at specific points(ie, acupoints), has growing in popularity world-wide to treat various diseases effectively, especially acute and chronic pain. In parallel, interest in the physiological mechanisms underlying acupuncture analgesia, particularly the neural mechanisms have been increasing. Over the past decades, our understanding of how the central nervous system and peripheral nervous system process signals induced by acupuncture has developed rapidly by using electrophysiological methods. However, with the development of neuroscience, electrophysiology is being challenged by calcium imaging in view field, neuron population and visualization in vivo. Owing to the outstanding spatial resolution, the novel imaging approaches provide opportunities to enrich our knowledge about the neurophysiological mechanisms of acupuncture analgesia at subcellular, cellular, and circuit levels in combination with new labeling, genetic and circuit tracing techniques. Therefore, this review will introduce the principle and the method of calcium imaging applied to acupuncture research. We will also review the current findings in pain research using calcium imaging from in vitro to in vivo experiments and discuss the potential methodological considerations in studying acupuncture analgesia.

关键词： acupuncture research calcium imaging optical imaging nervous system

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Advances in the study of mitophagy in osteoarthritis

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2024年第3期25卷 197-211页

作者： Hong CAO xuchang ZHOU Bowen xu Han HU Jianming GUO Miao WANG nan li Jun ZOU Department of Sport Rehabilitation Shanghai University of SportShanghai 200438China National Key Laboratory of Immunity and Inflammation Naval Medical UniversityShanghai 200433China School of Sport Medicine and Rehabilitation Beijing Sport UniversityBeijing 100084China

Osteoarthritis(OA),characterized by cartilage degeneration,synovial inflammation,and subchondral bone remodeling,is among the most common musculoskeletal disorders globally in people over 60 years of *** initiation and progression of OA involves the abnormal metabolism of chondrocytes as an important pathogenic *** degeneration features mitochondrial dysfunction as one of the important causative factors of abnormal chondrocyte ***,maintaining mitochondrial homeostasis is an important strategy to mitigate *** is a vital process for autophagosomes to target,engulf,and remove damaged and dysfunctional mitochondria,thereby maintaining mitochondrial *** studies have revealed a strong association between mitophagy and OA,suggesting that the regulation of mitophagy may be a novel therapeutic direction for *** reviewing the literature on mitophagy and OA published in recent years,this paper elaborates the potential mechanism of mitophagy regulating OA,thus providing a theoretical basis for studies related to mitophagy to develop new treatment options for OA.

关键词： Mitophagy Osteoarthritis Chondrocyte Mitochondria Apoptosis

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