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A new panaxadiol from the acid hydrolysate of Panax ginseng

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Chinese Chemical Letters 2009年第6期20卷 687-689页

作者： li na Tao Qin meng Jian Yuan Yin Rui Xing Hao Ran Guo Department of Traditional Chinese Medicinal Chemistry Pharmacy College Jilin University Changchun 130021 China

A new panaxadiol （compound 1） was obtained from the acid hydrolysate of the total ginsenosides of Panax ginseng C. A. Meyer （Araliaceae）. On the basis of spectroscopic data and single-crystal X-ray diffraction dat... 详细信息

关键词： Panax ginseng Ginsenoside Acid hydrolysate

C与na掺杂AlN电子结构与光学性质的第一性原理研究

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原子与分子物理学报 2024年第2期41卷 24-30页

作者：苏尔琴刘纪博李梦娜于宪省郭思嘉张丽丽赵旭才雷博程伊犁师范大学、物理科学与技术学院、新疆凝聚态相变与微结构重点实验室伊宁835000

基于密度泛函理论(DFT)的平面波超软赝势法,计算了本征AlN,C-AlN,na-AlN以及C-na-AlN四种体系的电子结构和光学性质.得出结论:掺杂后各体系与本征AlN相比发生了晶格畸变,C-na-AlN体系的结合能最小,体系最稳定.掺杂体系相比于本征AlN,禁... 详细信息

基于密度泛函理论(DFT)的平面波超软赝势法,计算了本征AlN,C-AlN,na-AlN以及C-na-AlN四种体系的电子结构和光学性质.得出结论:掺杂后各体系与本征AlN相比发生了晶格畸变,C-na-AlN体系的结合能最小,体系最稳定.掺杂体系相比于本征AlN,禁带宽度都有不同程度的减小,导致电子在体系内跃迁时的概率增大,其中C-na-AlN体系尤为明显,电子跃迁所需要的能量更小.掺杂后吸收带边发生了红移,拓宽了AlN体系对光的响应范围,增强了光吸收,并且C-na-AlN体系在可见光区域内光吸收能力最强,在介电函数图的分析中可以得到,C-na-AlN体系的介电常数最大,表明其电荷束缚能力最强,体系稳定性强,极化能力最好.

关键词： AlN 电子结构光学性质第一性原理

Effects of radix curcumae-derived diterpenoid C on Helicobacter pylori-induced inflammation and nuclear factor kappa B signal pathways

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World Journal of Gastroenterology 2013年第31期19卷 5085-5093页

作者： Xuan Huang Bin Lv Shuo Zhang Qun Dai Bing-Bing Chen li-na meng Department of Gastroenterology the First Affiliated Hospital Zhejiang Chinese Medical University

AIM:To study effect of diterpenoid C extracted from radix curcumae on Helicobacter pylori(***)-infected inflammation,intestinal metaplasia,and nuclear factor kappa B(NF-κB)signaling pathway in ***:We used I-type *** to infect human gastric epithelial gastric epithelium cell line(GES-1)cell lines,and then ***-infected GES-1 cells were treated with radix curcumae(RC)-derived diterpenoid C of different concentrations(5,10,20μg/mL)and *** expression of p65,IκB kinase(IKK)αand IKKγproteins was detected with Western blotting,and the expression of interleukin(IL)-8,IL-6 and IL-4 was determined with enzyme-linked immunosorbent assay *** were analyzed using SPSS software *** comparisons between groups of more than two unpaired values,one-way analysis of variance(ANOVA)was *** an ANOVA F value was significant,post hoc comparisons were performed between *** results were not normally distributed,the Mann-Whitney U test was used to compare two groups of unpaired values,whereas for comparisons between groups of more than two unpaired values,the Kruskal-Wallis H test was *** significance was established at Plin all were 5μg/mL for gastric GES-1 *** expression of IL-8 was significantly increased,especially at 12 h time point;and the expression of IL-4 was decreased in *** GES-1 *** ***-infected GES-1 cells were treated with RC-derived diterpenoid C of different concentrations and amoxicillin,the expression of IL-8was decreased at 12,24,48,72 h points(P<0.01),especially in high-concentration diterpenoid C(20μg/mL)group;and the expression of IL-4 was increased,especially in moderate and high-concentration diterpenoid C(10 and 20μg/mL)***-derived diterpenoid C had the inhibitory effects on ***-induced p65 translocation from cytopla

关键词： Radix curcumae-derived diterpenoid C Helicobacter pylori Nuclear factor-κB Inflammatory cytokine

Tongguan liqiao acupuncture therapy improves dysphagia after brainstem stroke

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Neural Regeneration Research 2016年第2期11卷 285-291页

作者： Chun-hong Zhang Jin-ling Bian Zhi-hong meng li-na meng Xue-song Ren Zhi-lin Wang Xiao-yan Guo Xue-min Shi Department of Acupuncture and Moxibustion the First Teaching Hospital of Tianjin University of Traditional Chinese Medicine Department of Acupuncture and Moxibustion Tianjin University of Traditional Chinese Medicine

Tongguan liqiao acupuncture therapy has been shown to effectively treat dysphagia after stroke-based pseudobulbar paralysis. We presumed that this therapy would be effective for dysphagia after bulbar paralysis in patients with brainstem infarction. Sixty-four patients with dysphagia following brainstem infarction were recruited and divided into a medulla oblongata infarction group（n = 22）, a midbrain and pons infarction group（n = 16）, and a multiple cerebral infarction group（n = 26） according to their magnetic resonance imaging results. All patients received Tongguan liqiao acupuncture for 28 days. The main acupoints were Neiguan（PC6）, Renzhong（DU26）, Sanyinjiao（SP6）, Fengchi（GB20）, Wangu（GB12）, and Yifeng（SJ17）. Furthermore, the posterior pharyngeal wall was pricked. Before and after treatment, patient swallowing functions were evaluated with the Kubota Water Test, Fujishima Ichiro Rating Scale, and the Standard Swallowing Assessment. The Barthel Index was also used to evaluate their quality of life. Results showed that after 28 days of treatment, scores on the Kubota Water Test and Standard Swallowing Assessment had decreased, but scores on the Fujishima Ichiro Rating Scale and Barthel Index had increased in each group. The total efficacy rate was 92.2% after treatment, and was most obvious in patients with medulla oblongata infarction（95.9%）. These findings suggest that Tongguan liqiao acupuncture therapy can repair the connection of upper motor neurons to the medulla oblongata motor nucleus, promote the recovery of brainstem infarction, and improve patient＇s swallowing ability and quality of life.

关键词： nerve regeneration traditional Chinese medicine acupuncture stroke bulbar palsy brain infarction swallowing disorder dysphagia acupoints neurological rehabilitation neural regeneration

Effects of parental involvement in infant care in neonatal intensive care units:a meta-analysis

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Frontiers of Nursing 2018年第3期5卷 207-215页

作者： Ting-Ting liu meng-Jie Lei Yu-Feng li Ya-Qian liu li-na meng Chang-De Jin School of Nursing Tianjin University of Traditional Chinese Medicine

Objective： This meta-analysis aimed to examine the effects of parental involvement in infant care in neonatal intensive care units （NlCUs）. Methods： PubMed, Embase, Cochrane library, Web of Science, China national Knowledge Infrastructure （CNKI）, Wanfang database, and VIP database were searched till November 2017. Randomized controlled trials （RCTs） and controlled clinical trials （CCTs） examining the effect of parental involvement in the NICU were considered for inclusion. Resulls： We included 10 studies （three RCTs, seven CCTs） with a total of 1,851 participants. The meta-analysis demonstrated that there were no statistically significant differences on nosocomial infection between two groups （risk ratio [RR] = 0.90, 95% CI 0.63-1.30, P = 0.58）. Compared with no parental involvement groups, parental involvement groups showed more weight gain （mean difference [MD] = 1.47, 95% CI 0.65-2.29, P 〈 0.05）, higher breast-feeding rate （RR = 1.38, 95% CI 1.25-1.53, P 〈 0.05）, lower readmission rate （RR = 0.35, 95% CI 0.15-0.80, P 〈 0.05）, and higher satisfaction rate （RR = 1.09, 95% CI 1.02-1.16, P 〈 0.05）.Conclusions： Parentaiinvolvement in the NICU interventions could not increase the rate of nosocomial infection of neonates, but could improve their weight gain, breast-feeding and parental satisfaction and decrease their readmission. However, since the conclusion of this meta-analysis was drawn based on the limited number of high-quality RCTs, more hioh-quality studies should be conducted in the future to confirm its positive intervention effects.

关键词： family integrated care intensive care units neonatal infant newbom meta-analysis

Muscovite is protective against non-steroidal anti-inflammatory drug-induced small bowel injury

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World Journal of Gastroenterology 2014年第31期20卷 11012-11018页

作者： Chen Huang Bin Lu Yi-Hong Fan Lu Zhang Ning Jiang Shuo Zhang li-na meng Department of Gastroenterology The First Affiliated Hospital of Zhejiang Chinese Medical University

AIM: To evaluate the effect of muscovite in preventing small bowel injury induced by nonsteroidal anti-inflammatory drugs (NSAIDs).

关键词： Muscovite Nonsteroidal anti-inflammatory drugs Small intestinal injury Video capsule endoscopy

Expression of p-STAT3 and vascular endothelial growth factor in MNNG-induced precancerous lesions and gastric tumors in rats

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World Journal of Gastrointestinal Oncology 2016年第3期8卷 305-313页

作者： Xiao-Yan Wang Lou-Lei Wang Xuan Zheng li-na meng Bin Lyu Hai-Feng Jin the First Affiliated Hospital of Zhejiang University the First Affiliated Hospital of Zhejiang Chinese Medicine University

AIM: To investigate the dynamic expression of p-signal transducer and activator of transcription 3 (STAT3) and vascular endothelial growth factor (VEGF) in the formation of gastric tumors induced by drinking water containing N-methyl-N’-nitro-N-nitrosoguanidine (MNNG) in Wistar rats. METHODS: One hundred and twenty Wistar rats were randomly divided into two groups (60 in each group): Control group and Model group. The rats in each group were then randomly divided into three groups (20 in each group): C/M15, C/M25 and C/M40 (15, 25 and 40 represent the number of feeding weeks from termination). Rats in the control group received normal drinking water and rats in the model group received drinking water containing 100 μg/mL MNNG. Stomach tissues were collected at the end of the 15th, 25th and 40th week, respectively, for microscopic measurement using hematoxylin and eosin staining. The expression of p-STAT3 and VEGF in different pathological types of gastric tissue, including normal, inflammation, atrophy, hyperplasia and gastric stromal tumor, was observed by immunohistochemistry and Western blot, and the corelation between p-STAT3 and VEGF was analyzed. RESULTS: (1) The expression of p-STAT3 in tissue with gastritis, atrophy, dysplasia and gastric stromal tumor were significantly increased in the model group compared with the control group (2.5 ± 1.0, 2.75 ± 0.36, 6.2 ± 0.45, 5.67 ± 0.55 vs 0.75 ± 0.36, P = 0.026, 0.035, 0.001, 0.002, respectively); the expression of p-STAT3 in tissue with dysplasia was higher than that in samples with gastritis or atrophy (6.2 ± 0.45 vs 2.5 ± 1.0, P = 0.006; 6.2 ± 0.45 vs 2.75 ± 0.36, P = 0.005, respectively); however, the expression of p-STAT3 in gastritis and atrophy was not significantly different (P > 0.05); (2) the expression of VEGF in tissue with gastritis, atrophy, dysplasia and gastric stromal tumor was significantly inc

关键词： Wistar rat Precancerous gastric lesions Gastric tumor Vascular endothelial growth factor p-signal transducer and activator of transcription 3 N-methyl-N&rsquo -nitro-N-nitrosoguanidine

The guest CH_(3)CN molecule triggers solid-state photochromism in a Cu_(2)I_(2)-based MOF for advanced time-dependent encryption and inkless erasable printing

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Chinese Chemical Letters 2024年第3期35卷 532-537页

作者： meng-Juan Wang Bo li Yong-li Wei Shu-na Zhao Shuang-Quan Zang Henan Key Laboratory of Crystalline Molecular Functional Materials Henan International Joint Laboratory of Tumor Theranostical Cluster MaterialsGreen Catalysis Centerand College of ChemistryZhengzhou UniversityZhengzhou 450001China College of Chemistry and Pharmaceutical Engineering Nanyang Normal UniversityNanyang 473061China

It remains a big challenge to develop solid-state stimuli-responsive materials for time-dependent information encryption and inkless erasable printing with long retention ***,a 2D Cu_(2)I_(2)-based MOF with photoresponsive spiropyran(SP)groups orderly installed on its skeleton is *** structural isomerization from SP to colored merocyanine(MC)form can be triggered by removing the CH_(3)CN ***,the degree of structural isomerization and the retention time can be adjusted by controlling the amount of CH_(3)CN guests,exhibiting dynamic photochromic behavior with multicolor states and tunable retention *** on these advantages,time-dependent information encryption is successfully ***,the long retention time(>72 h)of the MC form under daylight conditions in the CH_(3)CN-removed Cu_(2)I_(2)-based MOF and good repeatability make it promising in various applications,such as temporary calendars,price-cards,billboards,and reusable identity *** work provides a novel design strategy to fabricate multi-functional MOF-based smart materials for challenging applications of time-dependent information encryption and inkless erasable printing.

关键词： Stimuli-responsive materials Spiropyran Solid-state photochromism Time-dependent encryption Inkless erasable printing

Rational Design of Ruddlesden-Popper Perovskite Ferrites as Air Electrode for Highly Active and Durable Reversible Protonic Ceramic Cells

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nano-Micro Letters 2024年第9期16卷 308-324页

作者： na Yu Idris Temitope Bello Xi Chen Tong liu Zheng li Yufei Song meng Ni Department of Building and Real Estate Research Institute for Sustainable Urban Development(RISUD)and Research Institute for Smart Energy(RISE)The Hong Kong Polytechnic UniversityHung HomKowloonHong KongPeople’s Republic of China The Hong Kong Polytechnic University Shenzhen Research Institute Shenzhen 518057GuangdongPeople’s Republic of China Department of Mechanical and Aerospace Engineering The Hong Kong University of Science and TechnologyClear Water BayHong KongPeople’s Republic of China

Reversible protonic ceramic cells(RePCCs)hold promise for efficient energy storage,but their practicality is hindered by a lack of high-performance air electrode ***-Popper perovskite Sr_(3)Fe_(2)O_(7−δ)(SF)exhibits superior proton uptake and rapid ionic conduction,boosting ***,excessive proton uptake during RePCC operation degrades SF’s crystal structure,impacting *** study introduces a novel A/B-sites co-substitution strategy for modifying air electrodes,incorporating Sr-deficiency and Nb-substitution to create Sr_(2.8)Fe_(1.8)Nb_(0.2)O_(7−δ)(D-SFN).Nb stabilizes SF’s crystal,curbing excessive phase formation,and Sr-deficiency boosts oxygen vacancy concentration,optimizing oxygen *** D-SFN electrode demonstrates outstanding activity and durability,achieving a peak power density of 596 mW cm^(−2)in fuel cell mode and a current density of−1.19 A cm^(−2)in electrolysis mode at 1.3 V,650℃,with excellent cycling *** approach holds the potential for advancing robust and efficient air electrodes in RePCCs for renewable energy storage.

关键词： Reversible protonic ceramic cells Air electrode Ruddlesden-Popper perovskite Hydration Oxygen reduction reaction