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Deposition of crackless freestanding diamond films on Mo substrates with Zr interlayer

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International Journal of Minerals,Metallurgy and Materials 2010年第2期17卷 246-250页

作者： Zheng liu Cheng-ming li liang-xian Chen li-mei Wang li-fu Hei Fan-xiu Lu School of Materials Science and Engineering University of Science and Technology Beijing Beijing 100083 China

The Mo substrate with Zr interlayer,namely composite substrate,was employed to solve the problem of crack formation in the freestanding diamond film *** diamond films deposited on the composite substrates by the direct current arc plasma jet chemical vapor deposition（CVD） method were investigated with scanning electron microscopy（SEM）,X-ray photoelectron spectroscopy （XPS）,X-ray diffraction（XRD）,and Raman *** addition,the stress distribution during the large area freestanding diamond film deposition on the composite substrate was analyzed based on the finite element model *** results reveal that Zr interlayer can be easily destroyed during the post-deposition cooling process,which is helpful for stress release and crack avoiding in diamond films.

关键词： chemical vapor deposition diamond film interlayer thermal stress finite element analysis

Generation of glyco-engineered BY2 cell lines with decreased expression of plant-specific glycoepitopes

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Protein & Cell 2011年第1期2卷 41-47页

作者： Bo-jiao Yin Ting Gao Nuo-yan Zheng Yin li San-yuan Tang li-ming liang Qi XIE State Key Laboratory of Plant Genomics National Center for Plant Gene ResearchInstitute of Genetics and Developmental BiologyChinese Academy of SciencesDatun RoadBeijing 100101China State Key Laboratory of Biocontrol School of Life SciencesSun Yat-sen(Zhongshan)University135 Xingang Road WGuangzhou 510275China

Plants are known to be efficient hosts for the production of mammalian therapeutic ***,plants produce complex N-glycans bearingβ1,2-xylose and coreα1,3-fucose residues,which are absent in *** immunogenicity and allergenicity of plant-specific Nglycans is a key concern in mammalian *** this study,we amplified the sequences of 2 plant-specific glycosyltransferases from Nicotiana tabacum *** Bright Yellow 2(BY2),which is a well-established cell line widely used for the expression of therapeutic *** expression of the endogenous xylosyltranferase(XylT)and fucosyltransferase(FucT)was downregulated by using RNA interference(RNAi)*** xylosylated and core fucosylated N-glycans were significantly,but not completely,reduced in the glycoengineered ***,these RNAi-treated cell lines were stable and viable and did not exhibit any obvious ***,this study may provide an effective and promising strategy to produce recombinant glycoproteins in BY2 cells with humanized N-glycoforms to avoid potential immunogenicity.

关键词： BY2 cells N-glycosylation glycosyltransferase RNA interference

A Self-test Prediction Model to Determine the Probability Risk of Non-alcoholic Fatty liver Disease

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Biomedical and Environmental Sciences 2020年第11期33卷 857-861页

作者： li Qiang SHEN Qun Lun XU Chao Nan li ming liang MA Zhi Min ZHANG Shan CHEN Shuo ZHANG Min Ying ZHANG Jing Bo liU Feng YANG Xing Hua Beijing Physical Examination Center Beijing 100077China Academy of Mathematics and Systems Science Chinese Academy of SciencesBeijing 100190China Medical Engineering Department Peking University Third HospitalBeijing 100191China School of Public Health Beijing Municipal Key Laboratory of Clinical EpidemiologyCapital Medical UniversityBeijing 100069China Cente Of Quality Control and Improvement for Physical Check Up Beijing MunicipalityBeijing 100077China School of Medicine Nankai UniversityTianjin 300071China

Non-alcoholic fatty liver disease(NAFLD)is the most common liver disease in *** studies have shown that NAFLD is associated with obesity,insulin resistance,type 2 diabetes,hypertension,hyperlipidemia,and metabolic syn... 详细信息

关键词： NAFLD Probability liver

Quantitative Analysis of the Loads Acting on the Abrasive Grits in the Diamond Sawing of Granites

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厦门大学学报（自然科学版） 2002年第S1期41卷 121-122页

作者： XU Xi-peng, li Yuan, ZENG Wei-ming, li liang-bin (Province Key Lab of Stone Machining, Huaqiao University, Quanzhou 362 011, China)

An experimental study was carried out to quantitati ve ly evaluate the loads acting on the diamond grits during circular sawing of two kinds of typical granite with diamond segmented saw blade. Measurements were mad e of the horizontal and vertical force components and the consumed power in order to obtain the tangential and the normal force components. The temperatures at the diamond-granite contact zone were measured using a foil thermocouple. T he measurement, together with the net sawing power, was subsequently used to est imate the energy partition to the granite by a temperature matching technique. B ased on the energy partition values, the temperatures at individual cutting poin ts were estimated using an analytical model. SEM was used to follow the topograp hies of worn diamond segments. The average force acting on each diamond grit was found to be only 4% of the diamond compressive strength measured by a static me thod. The strength disparity of diamond grits and the random protrusion of grits beyond bond matrix should be significant factors in accounting for the wear of diamond grits. The wear of diamond grits was also found to be closely related to the high temperatures generated at individual cutting points and the pop-outs of diamonds from the bond matrix might be mainly attributed to the heat conducte d to the segments.

关键词： force temperature diamond sawing granite dis parity

Analysis of geometric parameters of straight wall three-centered arch and stress of surrounding rock based on conformal mapping

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Yantu lixue/Rock and Soil Mechanics 2020年 41卷 74-84页

作者： Wu, Su li, Ke-Gang Wu, Shun-Chuan Wang, Hang-Long Qin, Qing-Ci li, ming-liang He, Fa-Yun Faculty of Land Resources Engineering Kunming University of Science and Technology Kunming 650093 China Yunnan Key Laboratory of Sino-German Blue Mining and Utilization of Special Underground Space Kunming 650093 China Kunming Prospecting Design Institute of China Nonferrous Metals Industry Co. Ltd. Kunming 650051 China

In order to obtain the mapping function with a much higher accuracy, the barrier function algorithm based on the fmincon optimization function is used to solve the mapping function. It is considered that the conformal mapping from the outer boundary of the straight wall three-centered arch to the outer domain of the unit circle can be realized by m = 18 and n = 6, which is superior to the traditional algorithm. Based on the calculation results of analytical solution, the shape effect and size effect caused by the change of geometric parameters of the straight wall three-centered arch tunnel on the surrounding rock stress are analyzed. The results show that the increase rate of stress concentration coefficient in the arc area of the tunnel with small arch width ratio is much larger. The large stress concentration coefficient in the arc area of the tunnel with width-height ratio close to 1 is at the arch shoulder, while the maximum value, which is small, occurs at the corner of the wall. On the contrary, the large stress concentration coefficient in the arc area of the tunnel with width-height ratio far less than 1 is far away from the arch shoulder, while the maximum value is far away from the corner of the wall. When the width-height ratio is equal to 1, the maximum value of stress concentration coefficient appears at the corner, which is approximately the same as that of the stress concentration coefficient at the arch shoulder. © 2020, Science Press. All right reserved.

关键词： Conformal mapping

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基于太赫兹时域光谱分析红层泥岩风化样本

光谱学与光谱分析 2016年第4期36卷 929-933页

作者：李明亮常天英崔洪亮吉林大学仪器科学与电气工程学院吉林长春130026

红层泥岩边坡的风化是一个普遍存在而又未完全解决好的问题。因风化而造成的不稳定红层泥岩边坡,在岩土体重力、震动及其他因素作用下,常常发生危害性的变形与破坏,导致崩塌滑坡、落石和泥石流等地质灾害。风化深度是红层泥岩边坡治理... 详细信息

红层泥岩边坡的风化是一个普遍存在而又未完全解决好的问题。因风化而造成的不稳定红层泥岩边坡,在岩土体重力、震动及其他因素作用下,常常发生危害性的变形与破坏,导致崩塌滑坡、落石和泥石流等地质灾害。风化深度是红层泥岩边坡治理的重要依据之一。风化深度是指岩石破裂后在破裂面内侧产生的微裂隙或微裂隙带在风化作用下向岩石内部延伸的垂直距离。选择典型的红层泥岩边坡地带进行钻孔取样。太赫兹时域光谱技术是利用太赫兹脉冲表征物质性质的一种新兴光谱技术。实验使用太赫兹时域光谱系统测量所取得样本的太赫兹透射光谱。对所有样品的透射光谱进行分析,观察到各风化样品间的太赫兹透射光谱差别微小,且没有明显的特征吸收峰。为了获得取样地点的风化深度,基于太赫兹光谱建立一个智能,高效的回归预测支持向量机(SVM)模型来预测采样地点的风化深度。预测结果与实际深度相比较,所得相对误差小于7.09%。结果表明,基于太赫兹光谱的支持向量机(SVM)模型可以有效的区分样本以及预测深度,可以为红层泥岩边坡治理提供重要的参考。

关键词：太赫兹时域光谱支持向量机透射系数风化深度

圆管结构中周向导波非线性效应的模式展开分析

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物理学报 2015年第18期64卷 357-365页

作者：高广健邓明晰李明亮后勤工程学院重庆401331

在二阶微扰近似条件下,采用导波模式展开分析方法研究了圆管结构中周向导波的非线性效应.伴随基频周向导波传播所发生的二次谐波,可视为由一系列二倍频周向导波模式叠加而成.从动量定理出发,结合柱坐标系下非线性应力张量及其散度的数... 详细信息

在二阶微扰近似条件下,采用导波模式展开分析方法研究了圆管结构中周向导波的非线性效应.伴随基频周向导波传播所发生的二次谐波,可视为由一系列二倍频周向导波模式叠加而成.从动量定理出发,结合柱坐标系下非线性应力张量及其散度的数学表达式,针对圆管中某一基频周向导波模式,推导出相应的二倍频应力张量及二倍频彻体驱动力的数学表达式,建立了确定二倍频周向导波模式展开系数的控制方程,得到了伴随基频周向导波传播所发生的二次谐波声场的形式解.理论分析和数值计算表明,当构成二次谐波声场的某一二倍频周向导波模式与基频周向导波的相速度匹配时,该二倍频周向导波模式的位移振幅表现出随传播周向角积累增长的性质;当两者的相速度失配时,二倍频周向导波的振幅随传播周向角表现出"拍"效应.

关键词：周向导波非线性效应二次谐波发生模式展开分析

复合圆管界面特性对周向超声导波二次谐波发生效应的影响分析

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物理学报 2016年第19期65卷 158-167页

作者：李明亮邓明晰高广健后勤工程学院重庆401331

研究了复合圆管的管间界面特性对周向超声导波二次谐波发生效应所产生的影响.在二阶微扰近似条件下,将周向超声导波传播过程中的非线性效应视为其线性波动响应的一个二阶微扰.采用界面弹簧模型对复合圆管的管间界面特性进行描述.根据导... 详细信息

研究了复合圆管的管间界面特性对周向超声导波二次谐波发生效应所产生的影响.在二阶微扰近似条件下,将周向超声导波传播过程中的非线性效应视为其线性波动响应的一个二阶微扰.采用界面弹簧模型对复合圆管的管间界面特性进行描述.根据导波的模式展开分析方法,伴随基频周向超声导波传播所发生的二次谐波可视为由一系列二倍频周向导波模式叠加而成.管间界面特性的变化可从多个方面对二倍频周向导波模式的展开系数及声场产生影响,尤其是界面特性的变化所引起的周向超声导波相速度的改变,将显著地影响到二次谐波随传播周向角的积累增长程度.理论及数值分析结果表明,周向超声导波的二次谐波发生效应随管间界面特性的改变而发生非常敏感的变化,可将其用于准确定征复合圆管的管间界面性质.

关键词：管间界面特性周向超声导波二次谐波发生模式展开分析

City Size,Housing Price and Resident Income Gap

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City Size,Housing Price and Resident Income Gap