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Interoception mediates the association between social support and sociability in patients with major depressive disorder

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World Journal of Psychiatry 2024年第10期14卷 1484-1494页

作者： Wen-liang Wang Ji-Kang liu Yi-Fan Sun Xiao-Hong liu Yu-Hang Ma Xue-Zheng Gao li-min chen Zhen-He Zhou Hong-liang Zhou Department of Psychiatry The Affiliated Mental Health Center of Jiangnan UniversityWuxi 214151Jiangsu ProvinceChina Department of Psychiatry The Affiliated Mental Health Center of Nanjing Medical UniversityWuxi 214151Jiangsu ProvinceChina Department of Psychology The Affiliated Hospital of Jiangnan UniversityWuxi 214151Jiangsu ProvinceChina

BACKGROUND Interoception dysfunction has an important impact on the onset and development of major depressive disorder(MDD).Social support serves as a protective factor against MDD,and sociability also plays a significant role in this *** interconnected constructs-social support and sociability-play pivotal roles in ***,no research on the mechanisms underlying the associations be-tween social support and sociability,particularly the potential role of interocep-tion,have been ***,social support,and sociability,respectively.A mediation analysis model for the eight dimensions of intero-ception(noticing,not distracting,not worrying,attention regulation,emotional awareness,self-regulation,body listening,and trust),social support,and sociability were established to evaluate the mediating *** A partial correlation analysis of eight dimensions of the MAIA-2,SSRS,and TSBI scores,with demographic data as control variables,revealed pairwise correlations between the SSRS score and both the MAIA-2 score and TSBI *** the major depression(MD)group,the SSRS score had a positive direct effect on the TSBI score,while the scores for body listening,emotional awareness,self-regulation,and trust in the MAIA-2C had indirect effects on the TSBI *** the HC group,the SSRS score had a positive direct effect on the TSBI score,and the scores for attention regulation,emotional awareness,self-regulation,and trust in the MAIA-2C had indirect effects on the TSBI *** proportion of mediators in the MD group was lower than that in the HC *** Interoceptive awareness is a mediating factor in the association between social support and sociability in both HCs and depressed *** in interoceptive awareness might not only help improve emotional regulation in depressed patients but also enhance their social skills and support networks.

关键词： Interoception Social support Sociability Major depression Mediation analysis

Cortical Representation of Pain and Touch:Evidence from Combined Functional Neuroimaging and Electrophysiology in Non-human Primates

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Neuroscience Bulletin 2018年第1期34卷 165-177页

作者： li min chen Departments of Radiology and Radiological Sciences and Psychology Institute of Imaging Science Vanderbilt University Medical Center

Human functional MRI studies in acute and various chronic pain conditions have revolutionized how we view pain, and have led to a new theory that complex multi-dimensional pain experience （sensory-discriminative, affective/motivational, and cognitive） is represented by concurrent activity in widely-distributed brain regions （termed a network or pain matrix）. Despite these break- through discoveries, the specific functions proposed for these regions remain elusive, because detailed electrophys- iological characterizations of these regions in the primate brain are lacking. To fill in this knowledge gap, we have studied the cortical areas around the central and lateral sulci of the non-human primate brain with combined submillimeter resolution functional imaging （optical imaging and fMRI） and intracranial electrophysiological recording. In this mini-review, I summarize and present data showing that the cortical circuitry engaged in nociceptive processing is much more complex than previously recognized. Electrophysiological evidence supports the engage- ment of a distinct nociceptive-processing network within SI （i.e., areas 3a, 3b, 1 and 2）, SII, and other areas along the lateral sulcus. Deafferentation caused by spinal cord injury profoundly alters the relationships between fMRI and electrophysiological signals. This finding has significant implications for using fMRI to study chronic pain conditions involving deafferentation in humans.

关键词： Nociception Non-human primate Cortex Functional MRI Functional connectivity

Flavonoid triglycosides from the seeds of Camellia oleifera Abel

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Chinese Chemical Letters 2008年第11期19卷 1315-1318页

作者： li Chun Du Bei li Wu Jian min chen Department of Environmental Science ＆ Engineering Fudan University Shanghai 200433 China

Two flavonoid triglycosides, kaempferol 3-O-{ β-D-glucopyranosyl-（1→2）-[α-L-rhamnopyranosyl-（1→ 6）]-β-D-glucopyranoside} （1） and kaempferol 3-O-{ β-D-xylopyranosyl-（1 → 2）-[α-L-rhamnopyranosyl-（1→6）]-β-D-glucopyranoside } （2）, were isolated from the seed of Camellia oleifera Abel. The absolute configuration of compound 1 was established on the basis of its X-ray analysis. Their cytotoxic activities and anti-HIV-RT activities were evaluated.

关键词： Flavonoid triglycosides Camellia oleifera Abel Cytotoxic activity

Effects of deoxidizing degree on the pitting corrosion behavior of carbon and manganese steels

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International Journal of minerals,Metallurgy and Materials 2011年第2期18卷 169-177页

作者： Guo-liang Cao Cuo-min li Shan chen Wan-shun Chang Xue-qun chen College of Sciences Naval University of Engineering Wuhan 430033 China

Nine steels with different deoxidizing degrees and two comparative steels were selected. Their pitting initiation susceptibility was compared by means of potentiodynamic polarization tests in 3wt% NaCl solution. The pit propagation rate was evaluated in artificial sea water and 3wt% sea salt solution by simulating occluded corrosion cell （SOCC） test and hanging plate test, respectively. The composition of inclusions and corrosive feature were studied by scanning electron microscopy （SEM）, electron probe micro-analysis （EPMA）, and optical microscopy （OM）. The results indicate that sulfide inclusions in steel are the sites for pit nucleation. The sulphide inclusions vary in shape from short spindle-like to long strip-like with increasing deoxidizing degree. Under the same conditions, the lower the deoxidizing degree gets, the lower the pitting initiation susceptibility becomes, and the stronger the resistance to pit propagation exhibits. For steels with different deoxidizing degrees, their pitting initiation susceptibility is mainly influenced by thermodynamic stability, while the pit propagation rate is primarily subject to the characteristics of inclusions in steel.

关键词： carbon steel manganese steel pitting deoxidization inclusions

Analysis on the time-domain characteristics of botnets control traffic

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The Journal of China Universities of Posts and Telecommunications 2011年第2期18卷 106-113页

作者： li Wei-min MIAO chen liU Fang LEI Zhen-ming School of Information and Communication Engineering Beijing University of Posts and Telecommunications Beijing 100876 China

Botnets are networks composed with malware-infect ed *** are designed and organized to be controlled by an *** victims are infected through their inappropriate network behaviors in most cases,the Internet protocol（IP） addresses of infected bots are ***,a bot can get an IP address through dynamic host configuration protocol（DHCP）,so they need to get in touch with the controller initiatively and they should attempt continuously because a controller can＇t be always *** whole process is carried out under the command and control（C＆C） *** goal is to characterize the network traffic under the C＆C channel on the time *** analysis draws upon massive data obtained from honeynet and a large Internet service provider（ISP） *** extract and summarize fingerprints of the bots collected in our ***,with the fingerprints,we use deep packet inspection（DPI） Technology to search active bots and controllers in the ***,we gather and analyze flow records reported from network traffic monitoring *** this paper,we propose a flow record interval analysis on the time domain characteristics of botnets control traffic,and we propose the algorithm to identify the communications in the C＆C channel based on our *** that,we evaluate our approach with a 3.4 GB flow record trace and the result is *** addition,we believe that our work is also useful information in the design of botnet detection schemes with the deep flow inspection（DFI） technology.

关键词： botnet detection netflow record time domain analysis deep flow inspection

Aerodynamic Performance of Three Flapping Wings with Unequal Spacing in Tandem Formation

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Journal of Bionic Engineering 2024年第4期21卷 1662-1676页

作者： min Chang Ziyi Xu Zengshuang chen li li Xueguang Meng Unmanned System Research Institute National Key Laboratory of Unmanned Aerial Vehicle TechnologyNorthwestern Polytechnical UniversityXi’an710072People’s Republic of China State Key Laboratory for Strength and Vibration of Mechanical Structures School of Aerospace EngineeringXi’an Jiaotong UniversityXi’an710049People’s Republic of China Xi’an Aeronautics Computing Technique Research Institute Aviation Industry Corporation of ChinaXi’an710076People’s Republic of China

To better understand the aerodynamic reasons for highly organized movements of flying organisms,the three-flapping wing system in tandem formation was studied numerically in this *** from previous relevant studies on the multiple flapping wings that are equally spaced,this study emphasizes the impact of unequal spacing between individuals on the aerodynamics of each individual wing as well as the whole *** is found that swapping the distance between the first and second wing with the distance between the second wing and the rearmost wing does not affect the overall aerodynamic performance,but significantly changes the distribution of aerodynamic benefits across each *** the whole flapping cycle,three effects are at *** narrow channel effect and the downwash effect can promote and weaken the wing lift,respectively,while the wake capture effect can boost the *** also shows that these effects could be manipulated by changing the spacing between adjacent *** findings provide a novel way for flow control in tandem formation flight and are also inspiring for designing the formation flight of bionic aircraft.

关键词： Three flapping wings Unequal spacing Aerodynamic performance Tandem formation

Flexible printed three dimensional(3D) integrated carbon nanotube complementary metal oxide semiconductor(CMOS) thin film transistors and circuits

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Science China(Information Sciences) 2024年第09期67卷 280-293页

作者： Zhaofeng chen Jiaqi li min li Hongxuan GUO Jianwen ZHAO SEU-FEI Nano-Pico Center Key Laboratory of MEMS of Ministry of Education Southeast University Printable Electronics Research Center Division of Nanodevices and Related NanomaterialsSuzhou Institute of Nano-Tech and Nano-Bionics Chinese Academy of Sciences School of Nano Technology and Nano Bionics University of Science and Technology of China

The threshold voltage modulation of carbon nanotube thin-film transistors（TFTs） and flexible three-dimensional（3D） integration circuits has become hot research topics for carbon-based electronics. In this paper, a doping-free gate electrode technology is introduced to significantly modulate the threshold voltage of polymer-sorted semiconducting single-walled carbon nanotube（sc-SWCNT） TFTs in combination with the highly effective gate-controlling ability of solid-state electrolyte thin films as the dielectrics. A systematic investigation was conducted on the impact of printed silver, evaporated silver, and evaporated aluminum（Al） gate electrodes on the threshold voltage of flexible printed bottom-gate and top-gate SWCNT TFTs. The results indicate that the SWCNT TFTs with Al gate electrodes exhibit enhancement-mode characteristics with excellent electrical properties, such as the negative threshold voltages（-0.6 V）, high Ion/Ioff（up to 10～6）, low subthreshold swing(61.4 mV · dec-1), and small hysteresis. It is attributed to either the formation of lower work function thin films（Al2O3） at the electrode/dielectric layer interfaces through the natural oxidation of the Al bottom-gate electrodes or the dipole reaction of the Al top-gate electrodes from X-ray photoelectron spectroscopy（XPS） and ultraviolet photoelectron spectroscopy（UPS） data. In addition, 3D complementary metal-oxide-semiconductor（CMOS） inverters with common gate electrodes were constructed using the resulting enhancement-mode P-type SWCNT TFTs and matched N-type SWCNT TFTs, which shows high voltage gain（34）, rail-to-rail output and high noise margins(80.04%, VDD=-1 V)as well good mechanical flexibility at low operation voltages. It demonstrates that SWCNT TFTs have great advantages for building large-scale 3D flexible integrated circuits.

关键词： three-dimensional CMOS circuits printing technology polymer-sorted semiconducting carbon nanotubes enhancement-mode thin-filmtransistors threshold voltage modulation

A survey of decision making in adversarial games

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Science China(Information Sciences) 2024年第4期67卷 85-112页

作者： Xiuxian li min MENG Yiguang HONG Jie chen College of Electronics and Information Engineering Tongji University Shanghai Research Institute for Intelligent Autonomous Systems

In many practical applications, such as poker, chess, drug interdiction, cybersecurity, and national defense, players often have adversarial stances, i.e., the selfish actions of each player inevitably or intentionally inflict loss or wreak havoc on other players. Therefore, adversarial games are important in realworld applications. However, only special adversarial games, such as Bayesian games, are reviewed in the literature. In this respect, this study aims to provide a systematic survey of three main game models widely employed in adversarial games, i.e., zero-sum normal-form and extensive-form games, Stackelberg(security) games, and zero-sum differential games, from an array of perspectives, including basic knowledge of game models,(approximate) equilibrium concepts, problem classifications, research frontiers,(approximate) optimal strategy-seeking techniques, prevailing algorithms, and practical applications. Finally, promising future research directions are also discussed for relevant adversarial games.

关键词： adversarial games zero-sum games Stackelberg games differential games Nash equilibrium correlated equilibrium regret

Health Management of Breast Cancer Survivors

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Clinical oncology and cancer researeh 2009年第3期6卷 174-178页

作者： min li Juan chen Zhendong chen Department of Oncology the First AffiliatedHospital of Anhui Medical University Hefei20022 Anhui Province China

Breast cancer is defined as a chronic *** amounts of attention have been paid to the healthmanagement of breast cancer survivors. An important issue ishow to find the most appropriate method of follow-up in orderto detect long-term complications of treatment, local recurrenceand distant metastasis and to administer appropriate treatmentto the survivors with recurrence in a timely fashion. Differentoncology organizations have published guidelines for followingup breast cancer survivors. However, there are few articles onthis issue in China. Using the published follow-up guidelines,we analyzed their main limitations and discussed the content,follow-up interval and economic benefits of following up breastcancer survivors in an effort to provide suggestions to *** on a large number of clinical trials, we discussed the roleof physical examination, mammography, liver echograph, chestradiography, bone scan and so on. We evaluated the effects ofthe above factors on detection of distant disease, survival time,improvement in quality of life and time to diagnosis of *** results of follow-up carried out by oncologists and primaryhealth care physicians were compared. We also analyzed thecorrelation factors for the cost of such follow-up. It appears thatfollow-up for breast cancer survivors can be carried out effectivelyby trained primary health care physicians. If anything unusualarises, the patients should be transferred to specialists.

关键词： breast cancer survivor health management.