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Research progress of “shared nurses” under the family community hospital integrated management mode

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Frontiers of Nursing 2020年第1期7卷 13-17页

作者： Xiao-Jing Guo li-li wei Yu-Biao Gai Si-Long Gao Hui Tian Xin-Hui li ICU The Affiliated Hospital of Qingdao UniversityQingdaoShandong 266000China

In order to meet the diverse and multilevel health service needs of the people,following the implementation of the“multi-point practice”of registered physicians by the government in 2009,many pilot projects on the legality of“shared nurses”have been carried out,but there are many difficulties in the *** reviewing and researching the relevant literature inland and abroad,this study explores the application of family-community-hospital integrated medical and nursing management model in order to provide a reference for the development and management of“shared nurses”in China.

关键词： nursing management multipoint practice integrated management

Research on Stock Price Prediction Method Based on the GAN-LSTM-Attention Model

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Computers, Materials & Continua 2025年第1期82卷 609-625页

作者： Peng li Yanrui wei lili Yin College of Computer Science and Technology Harbin University of Science and TechnologyHarbin150006China

Stock price prediction is a typical complex time series prediction problem characterized by dynamics,nonlinearity,and *** paper introduces a generative adversarial network model that incorporates an attention mechanism(GAN-LSTM-Attention)to improve the accuracy of stock price ***,the generator of this model combines the Long and Short-Term Memory Network(LSTM),the Attention Mechanism and,the Fully-Connected Layer,focusing on generating the predicted stock *** discriminator combines the Convolutional Neural Network(CNN)and the Fully-Connected Layer to discriminate between real stock prices and generated stock ***,to evaluate the practical application ability and generalization ability of the GAN-LSTM-Attention model,four representative stocks in the United States of America(USA)stock market,namely,Standard&Poor’s 500 Index stock,Apple Incorporatedstock,AdvancedMicroDevices Incorporatedstock,and Google Incorporated stock were selected for prediction experiments,and the prediction performance was comprehensively evaluated by using the three evaluation metrics,namely,mean absolute error(MAE),root mean square error(RMSE),and coefficient of determination(R2).Finally,the specific effects of the attention mechanism,convolutional layer,and fully-connected layer on the prediction performance of the model are systematically analyzed through ablation *** results of experiment show that the GAN-LSTM-Attention model exhibits excellent performance and robustness in stock price prediction.

关键词： Stock price prediction generative adversarial network attention mechanism time-series prediction

The function of three indigenous plasmids in Mesorhizobium huakuii 2020 and its symbiotic inter-action with Sym pJB5JI of Rhizobium leguminosarum

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Science China(life Sciences) 2008年第4期51卷 353-361页

作者： YANG ChengYun, li YouGuo, wei li, CHENG GuoJun & ZHOU JunChu State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China State Key Laboratory of Agricultural Microbiology Huazhong Agricultural University Wuhan 430070 China

A Mesorhizobium huakuii strain 2020, isolated from a rice-growing field in southern China, contains three indigenous plasmids named p2020a, p2020b and p2020c, respectively. The plasmids were deleted via Tn5-sacB insertion, and two cured derivatives were obtained. Interestingly, the mutant 2020D29 curing of p2020c could significantly enhance the capacity of symbiotic nitrogen fixation. But the mutant 2020D8 curing of p2020b lost the ability to nodulate Astragalus sinicus. Furthermore, the third plasmid p2020a could be hardly eliminated, suggesting that some house-keeping genes necessary for strain growth located on this plasmid. Then the Sym plasmid pJB5JI of R. leguminosarum bv. viciae was transferred into 2020 and its cured derivatives. The pot plant test showed that the ability of competition and symbiotic nitrogen fixation of transconjugant 2020-137 (pJB5JI) was increased evidently in con-trast to 2020. pJB5JI could not restore the ability of 2020D8 to nodulate Astragalus sinicus. 2020D8-8 (pJB5JI) could form ineffective nodules on peas, which implied that the symbiotic plasmid pJB5JI could express its function at the chromosomal background of Mesorhizobium huakuii 2020. The plas-mid stability was checked in transconjugants under free-living and during symbiosis. The results indi-cated that pJB5JI failed to be detected in some nodule isolates. That Km resistance gene could be am-plified from all transconjugants and nodule isolates suggested that pJB5JI was fully or partially inte-grated into the chromosome of recipients.

关键词： Mesorhizobium huakuii indigenous plasmids pJB5JI symbiotic interaction plasmid curing

Non-composite combined liver and intestinal allotransplantation

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Hepatobiliary & Pancreatic Diseases International 2006年第4期5卷 613-616页

作者： Ning li, You-Sheng li, Yuan-Xin li, wei-Ming Zhu, Xiao-Dong Ni, liang Zhu, Bin Cao, wei-Su li, Kai Luo and Jie-Shou li Research Institute of General Surgery, Jinling Hospital, Nanjing 210002, China Research Institute of General Surgery Jinling Hospital Nanjing 210002 China. liningrigs@***

BACKGROUND: Patients with short bowel syndrome may require combined liver and intestinal transplantation due to total parenteral nutrition(TPN)-related liver damage. We report combined liver and intestinal allotransplantation as a non-composite technique in a patient in China. METHODS: During the operation, a 380 cm long intestine was transplanted with systemic drainage and aortic inflow, while the liver graft was placed in a piggyback fashion. Warm ischemic time of the donor graft was 2 minutes and 30 seconds, and cold ischemic time for intestinal and the liver graft was 6 hours and 40 minutes and 8 hours and 7 minutes, respectively. Immunosuppressants used after operation included tacrolimus, methylprednisolone, mycophenolate mofetil and Zenapax. RESULTS: The recipient recovered with no evidence of rejection and was kept well on tube feeding. Eventually, he died of massive hemorrhage of the thoracic cavity on day 210 after transplantation. CONCLUSION: The non-composite combined liver and intestinal allotransplantation is superior to composite technique in adult patients, particularly those who have had abdominal infection or repeated abdominal operations.

关键词： transplantation intestinal transplantation liver transplantation combined liver and intestinal transplantation

Application of machine learning algorithm for predicting gestational diabetes mellitus in early pregnancy

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Frontiers of Nursing 2021年第3期8卷 209-221页

作者： li-li wei Yue-Shuai Pan Yan Zhang Kai Chen Hao-Yu Wang Jing-Yuan Wang Department of Nursing The Affiliated Hospital of Qingdao UniversityQingdaoShandong 266003China Intensive Care Unit The Affiliated Hospital of Qingdao UniversityQingdaoShandong 266003China Research Institute for Mathematics and Interdisciplinary Sciences Qingdao University of Science and TechnologyQingdaoShandong 266061China Department of Critical Care and Respiratory Medicine The Affiliated Hospital of Qingdao UniversityQingdaoShandong 266003China

Objective:To study the application of a machine learning algorithm for predicting gestational diabetes mellitus(GDM)in early ***:This study identified indicators related to GDM through a literature review and expert *** women who had attended medical institutions for an antenatal examination from November 2017 to August 2018 were selected for analysis,and the collected indicators were retrospectively *** on Python,the indicators were classified and modeled using a random forest regression algorithm,and the performance of the prediction model was ***:We obtained 4806 analyzable data from 1625 pregnant *** these,3265 samples with all 67 indicators were used to establish data set F1;4806 samples with 38 identical indicators were used to establish data set *** of F1 and F2 was used for training the random forest *** overall predictive accuracy of the F1 model was 93.10%,area under the receiver operating characteristic curve(AUC)was 0.66,and the predictive accuracy of GDM-positive cases was 37.10%.The corresponding values for the F2 model were 88.70%,0.87,and 79.44%.The results thus showed that the F2 prediction model performed better than the F1 *** explore the impact of sacrificial indicators on GDM prediction,the F3 data set was established using 3265 samples(F1)with 38 indicators(F2).After training,the overall predictive accuracy of the F3 model was 91.60%,AUC was 0.58,and the predictive accuracy of positive cases was 15.85%.Conclusions:In this study,a model for predicting GDM with several input variables(e.g.,physical examination,past history,personal history,family history,and laboratory indicators)was established using a random forest regression *** trained prediction model exhibited a good performance and is valuable as a reference for predicting GDM in women at an early stage of *** addition,there are cer tain requirements for the propor tions of negative and posi

关键词： early prediction gestational diabetes mellitus machine learning algorithm random forest regression

Antifungal activity of ibuprofen against aspergillus species and its interaction with common antifungal drugs

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Chinese Medical Journal 2010年第19期123卷 2701-2705页

作者： li li-juan CHEN wei XU Hui WAN Zhe li Ruo-yu liU wei Department of Dermatovenerology Peking University First Hospital Research Center for Medical Mycology Peking University Beijing 100034 China

Background The incidence of invasive aspergillosis （IA） has increased in frequency in immunocompromised patients with a variety of diseases. The poor prognosis might be due to limited treatment option. This study aimed to evaluate antifungal activity of ibuprofen against clinical isolates of aspergillus species, as well as its interaction with azoles or with amphotericin B or with micafungin. Methods Antifungal activity of ibuprofen against 10 strains of Aspergillus fumigatus, Aspergillus flavus, and Aspergillus terreus were tested with both disk diffusion assay and standard broth microdilution method. To determine whether ibuprofen combined with itraconazole, voriconazole, amphotericin B, or micafungin had interactive effects on aspergillus spp., we used both disk diffusion assay and Chequerboard method. Results As for disk diffusion method, ibuprofen produced a zone of growth inhibition with diameters of （20.1±3.9） mm at 48 hours of incubation. As for broth microdilution method, the minimal inhibitory concentration （MIC） ranges of ibuprofen against aspergillus spp. were 1000-2000 μg/ml, and the minimal fungicidal concentration （MFC） ranges of that was 2000-8000 μg/ml. For 2 of 5 isolates, when ibuprofen combined with itraconazole or voriconazole, the zones of growth inhibition were larger than those of the individual drug. The results of Chequerboard method showed that fractional inhibitory concentration index （FICI） ranges were 1.125-2.500. Conclusions Ibuprofen is active against aspergillus spp.. And ibuprofen does not affect the in vitro activity of itraconazole, voriconazole, amphotericin B or micafungin against aspergillus spp.

关键词： aspergillus spp. ibuprofen antifungal susceptibility drug interaction

Quantum public-key crypto via EPR pairs

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 58-63页

作者： Xiang-Qun Fu Hong-wei li Jian-Hong Shi Tan li Wan-Su Bao Henan Key Laboratory of Quantum Information and Cryptography Information Engineering University Synergetic Innovation Center of Quantum Information and Quantum Physics University of Science and Technology of China

With the development of quantum computing technology, quantum public-key cryptography is gradually becoming an alternative to the existing classical public-key cryptography. This paper designs a quantum trapdoor one-way function via EPR pairs and quantum measurements. Based on this, a new quantum public-key cryptosystem is presented, which offers forward security,and can resist the chosen-plaintext attack and chosen-ciphertext attack. Compared with the existing quantum public-key cryptos,eavesdropping can be automatically detected in this new quantum public-key cryptosystem under a necessary condition, which is also detailed in the paper.

关键词： quantum public-key crypto trapdoor one-way function EPR pairs

Influence of Alumina Addition on the Optical Property of Zirconia/Alumina Composite Dental Ceramics

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Journal of Wuhan University of Technology(Materials Science) 2011年第4期26卷 690-695页

作者：蒋丽李伟 State Key Laboratory of Oral Diseases Sichuan University

The influence of various alumina additions on the optical property of zirconia/alumina composite ceramics was investigated. The relative sintered densities, transmittances, color and the microstructure of the composite ceramics were studied. The experimental results showed that the relative sintered densities and transmittances decreased with alumina addition. The lightness increased obviously but the chroma change was small. Pure zirconia nanopowders sintered densely could obtain the relatively high transmittance, while the transmittance and the lightness of slight addition changed significantly. The zirconia/alumina composite ceramics with alumina addition less than 7.5wt% could achieve the relatively stable and reliable optical properties.

关键词： alumina addition zirconia/alumina ceramics transmittance color optical properties

Effect of respiratory training apparatus and vibration expectoration vest on expectoration in patients with lung cancer resection

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Frontiers of Nursing 2018年第4期5卷 285-289页

作者： Xiao-Jing Guo li-li wei Xin-Hui li Ning-Ning Yu Shao-Bo Gao Dong-Yan Qin Fu-Mei Chu Kun li Cardiovascular Surgery Affiliated Hospital of Qingdao University Nursing Department Affiliated Hospital of Qingdao University Obstetrics Department Affiliated Hospital of Qingdao University Gynecology Department Affiliated Hospital of Qingdao University

Objective: The aim of this study was to explore the safe and effective method of expectoration in the preoperative period of patients with lung cancer resection and to promote the rehabilitation of ***: A total of 100 cases of lung cancer patients undergoing elective surgery were divided into the observation group and the control group, with 50 cases in each group. The control group was treated with vibration expectoration vest for expectoration during the perioperative period, and the observation group was treated with respiratory function exerciser that has expectoration function in the perioperative period, three times a day, and the effect was evaluated after 5 ***: The number of patients in the observation group after the first expectoration time was significantly less than that of the control group(Plization time was significantly shorter than that of the control group; and the difference was statistically significant(P<0.05).Conclusions: Lobectomy for lung cancer patients with perioperative respiratory training for respiratory function exercise, compared with conventional methods, is helpful for postoperative expectoration and to reduce the incidence of adverse events.

关键词： lung cancer sputum pain lung carcinoma physiatry lung function nursing intervention