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Covering corneal stromal lenticule for macular hole in pathological myopia

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International Journal of Ophthalmology(English edition) 2024年第9期17卷 1675-1680页

作者： Zi-Yan Tang Gang Qiao Xiao-Juan Zhang li-jun xie Qiang-Xing Zou Chun-Mei He Long Zhao Hua-Qing Yang Yu Quan Kui Cao Hui Jiang Yu-Kun He Wanjiang Eye Hospital of Mianyang Mianyang 621000Sichuan ProvinceChina

AIM:To evaluate the clinical effect of a new surgery technique(covering corneal stromal lenticule,CSL)for macular hole(MH)in pathological ***:This was a prospective non-randomized series case *** eyes of 14 patients whose axial length were more than 29 mm and suffered from MH and macular hole retinal detachment(MHRD)were included in this *** cases were treated with 25-gauge pars plana vitrectomy(PPV)with internal limiting membrane(ILM)peeling,covering CSL and C_(3)F_(8) gas *** cases were followed for 6mo,and the best-corrected visual acuity(BCVA),healing status of MH,the reattached rate of retinal detachment(RD),and reoperation rate were ***:All cases were successfully performed the surgery and the postoperative follow-up was *** surgery,MHs were healed in all 14 eyes(100%,14/14)after assessed by optical coherence *** reattachment of retina was achieved in all 6 eyes(100%,6/6)with *** was improved in 12 eyes(85.71%,12/14),and had no significant change in 2 eyes(14.29%,2/14).The overall mean BCVA was improved from 1.80±0.77 to 0.82±0.46 logMAR(F=10.46,Plications occurred in all ***:The new surgery technique(covering CSL)has high reattached rate of RD and high healing rate of MH in pathological myopia in the preliminary *** it can effectively improve the visual function of *** new technique offers meaningful new ideas for treating refractory MH in pathological myopia.

关键词： corneal stromal lenticule macular hole pathological myopia

A chemical labeling of N^(6)-formyl adenosine(f^(6)A) RNA

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Chinese Chemical Letters 2022年第3期33卷 1563-1566页

作者： li-jun xie Cui-lian lin li liu liang Cheng Beijing National Laboratory for Molecular Sciences(BNLMS) CAS Key Laboratory of Molecular Recognition and FunctionCAS Research/Education Center for Excellence in Molecular SciencesInstitute of ChemistryChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China

N^(6)-methyl adenosine (m^(6)A) is an eminent epigenetic mark in mRNAs that affects a broad range of biological functions in diverse species. However, the chemically inert methyl group prevents a direct labeling of this modification for subsequent detection and sequencing. Therefore, most current approaches for the labeling of m^(6)A still have limitations of relying on the utilization of corresponding methyltransferases, which resulted in the lacking of efficiency. Here we present an approach which selectively alkylated the N^(6)-formyl adenosine (f^(6)A), the key intermediate during chemical oxidation of m^(6)A, with an alkyne functionality that can be further labeled with click reactions. This covalent labeling approach will be able to facilitate in the affinity purification, detection and genome-wide profiling studies.

关键词： RNA epigenetics Chemical modulation Labeling Nucleic acids Alkylation

An efficient projection defocus algorithm based on multi-scale convolution kernel templates

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Journal of Zhejiang University-Science C(Computers and Electronics) 2013年第12期14卷 930-940页

作者： Bo ZHU li-jun xie Guang-hua SONG Yao ZHENG School of Aeronautics and Astronautics Zhejiang University Center for Engineering and Scientific Computation Zhejiang University

The focal problems of projection include out-of-focus projection images from the projector caused by incomplete mechanical focus and screen-door effects produced by projection pixilation. To eliminate these defects and enhance the imaging quality and clarity of projectors, a novel adaptive projection defocus algorithm is proposed based on multi-scale convolution kernel templates. This algorithm applies the improved Sobel-Tenengrad focus evaluation function to calculate the sharpness degree of intensity equalization and then constructs multi-scale defocus convolution kernels to remap and render the defocus projection image. The resulting projection defocus corrected images can eliminate out-of-focus effects and improve the sharpness of uncorrected images. Experiments show that the algorithm works quickly and robustly and that it not only effectively eliminates visual artifacts and can run on a self-designed smart projection system in real time but also significantly improves the resolution and clarity of the observer's visual perception.

关键词： Projection focal Sobel-Tenengrad evaluation function Projector defocus Multi-scale convolution kernels

Wheat Growth and Photosynthesis as Affected by Oxytetracycline as a Soil Contaminant

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Pedosphere 2011年第2期21卷 244-250页

作者： li Zhao-jun xie Xiao-Yu ZHANG Shu-Qing liANG Yong-Chao Institute of Agricultural Resources and Regional Planning Chinese Academy of Agricultural Sciences Key Laboratory of Crop Nu-trition and Fertilization Ministry of Agriculture of China Beijing 100081 (China)

Extensive worldwide use of oxytetracycline （OTC）, a member of the tetracyclines, has resulted in its accumulation in soils, posing a potential risk to food production and safety. A pair of OTC-sensitive （Heyou 1） and OTC-tolerant （Yannong 21） wheat （Tritieum aestivum L.） cultivars was compared hydroponically at 0.01, 0.02, 0.04, and 0.08 mmol L-10TC in terms of wheat growth and photosynthesis. Biomass and shoot length decreased significantly with the addition of OTC, with the decreases in dry biomass and shoot length being 5.61%-13.75% and 3.33%-8.57% larger, respectively, for Heyou 1 than Yannong 21. Photosynthesis of Heyou 1 was suppressed by OTC as indicated by the significant decreases in photosynthetic rate （PN）, transpiration rate （TR）, and stomatal conductance （GS） and the significant increase in intercellular CO2 concentrations （CI）, at all OTC levels. Stomatal limitation （LS） and water use eftlciencies （WUE） of Heyou i also increased significantly, but not at 0.08 mmol L-10TC. However, photosynthesis of Yannong 21 was suppressed by OTC only at high OTC levels from 0.02 to 0.08 mmol L-1 as indicated by the decreases in PN, GS, TR, and LS; at 0.01 mmol L-10TC, PN, CI, GS, and TR significantly increased. It was noted that WUE of Yannong 21 was not affected by OTC addition. The results from this hydroponic test suggested that OTC had a potential risk to crop growth through inhibition of photosynthesis, requiring further confirmation with soil tests.

关键词： biomass cultivar hydroponic test photosynthetic parameters tetracyclines

Mining item-item and between-set correlated association rules

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Journal of Zhejiang University-Science C(Computers and Electronics) 2011年第2期12卷 96-109页

作者： Bin SHEN Min YAO li-jun xie Rong ZHU Yun-ting TANG Ningbo Institute of Technology Zhejiang University Ningbo 315100 China School of Computer Science and Technology Zhejiang University Hangzhou 310027 China Center for Engineering & Scientific Computation School of Aeronautics and Astronautics Zhejiang University Hangzhou 310027 China

To overcome the failure in eliminating suspicious patterns or association rules existing in traditional association rules mining, we propose a novel method to mine item-item and between-set correlated association rules. First, we present three measurements: the association, correlation, and item-set correlation measurements. In the association measurement, the all-confidence measure is used to filter suspicious cross-support patterns, while the all-item-confidence measure is applied in the correlation measurement to eliminate spurious association rules that contain negatively correlated items. Then, we define the item-set correlation measurement and show its corresponding properties. By using this measurement, spurious association rules in which the antecedent and consequent item-sets are negatively correlated can be eliminated. Finally, we propose item-item and between-set correlated association rules and two mining algorithms, I&ISCoMine_AP and I&ISCoMine_CT. Experimental results with synthetic and real retail datasets show that the proposed method is effective and valid.

关键词： Item-item and between-set correlated association rules All-confidence All-item-confidence Item-set correlation Mining algorithms Pruning effect

Negative Effects of Oxytetracycline on Wheat (Triticum aestivum L.) Growth, Root Activity, Photosynthesis, and Chlorophyll Contents

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Agricultural Sciences in China 2011年第10期10卷 1545-1553页

作者： li Zhao-jun xie Xiao-yu ZHANG Shu-qing liANG Yong-chao Institute of Agricultural Resources and Regional Planning Chinese Academy of Agricultural Sciences~Key Laboratory of Crop Nutritionand Fertilization Ministry of Agriculture Beijing 100081 P.R.China

A solution culture experiment was performed to investigate the effects of oxytetracycline （OTC） on wheat （Triticum aestivum L.） growth, chlorophyll contents, and photosynthesis at five levels of 0, 10, 20, 40, and 80 mmol L-1 OTC. OTC is toxic to wheat. The wheat growth, especially wheat root was significantly decreased. Further OTC also significantly decreased root activity, chlorophyll contents, and photosynthetic parameters except for intercellular CO2 concentrations. The different responses of indicators such as root number, root activity and so on to OTC were also observed. The IC50 values for the tested indicators to OTC ranged from 7.1 to 113.4 mmol L-1 OTC. The order of indicator sensitivity to OTC was root number stomatal conductance chlorophyll a total chlorophyll photosynthetic rates total surface area transpiration rate chlorophyll b fresh weight of root dry weight of root total length dry weight of shoot = fresh weight of shoot total volume. The root number was more sensitive than other indicators with the IC50 value of 7.1 mmol L-1 OTC, and could be taken as the sensitive indicator to predict the hazards of OTC to wheat.

关键词： OTC wheat growth root morphological characteristics chlorophyll contents photosynthesis

Investigation on the influence of vortex generator on particle resuspension

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Particuology 2024年第3期86卷 126-136页

作者： Dongchi Yu jun-li lin Jin-Han xie ASML 80W Tasman DrSan Jose95134CaliforniaUSA Department of Mechanics and Engineering Science at College of Engineering and State Key Laboratory for Turbulence and Complex Systems Peking UniversityBeijing100081China

The vortex generator(VG)and its well-known effect in flow optimization are widely studied and employed across different engineering ***,while the same working principles of VG may be well suited for the applications on surface-cleaning technologies,such promising potential is hardly,if any,explored in the published ***,in the present study,the influence on flow-induced particle resuspension brought by a rectangular vG in a channel flow is investigated with the help of highfidelity computational fluid dynamics *** increases of particle removal forces and resuspension rates are discovered in long,strip-like regions with reduced boundary-layer thickness resulted from the vG-induced vortices,and the enhancement effect is especially significant for configurations with the VG installed at a greater angle of *** is also shown that while the resuspension enhancements on the lower and the upper surfaces of the channel exhibit distinct statistical characteristics,having a VG in the channel improves the overall particle-removing capability of the channel flow by introducing higher surface-averaged removal forces and particle resuspension *** but not least,the increase of resuspension rate is especially significant for the smaller,micron-scale particles which are otherwise hardly disturbed by a VG-less channel flow,and such resuspension-enhancement effectgenerally subsides with increasing particle size.

关键词： Particle resuspension Vortexgenerator CFD Surface cleaning

Control of Iodine Deficiency Disorders Following 10-Year Universal Salt Iodization in Hebei Province of China

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Biomedical and Environmental Sciences 2009年第6期22卷 472-479页

作者： SHENG-MIN LV li-jun xie RONG-HUA ZHOU ZHEN-SHUI CHONG li-HUI JIA JING MA jun ZHAO DONG XU Hebei Provincial Centre for Disease Control and Prevention Shijiazhuang 050021 Hebei China Hebei Provincial Bureau for Health Supervision Shijiazhuang 050071 Hebei China

Objective To evaluate the effectiveness of universal salt iodization （USI） for the control of IDD in Hebei province since it was implemented in 1995, identify the problems currently encountered in the implementation of USI and provide practical proposals for addressing these problems. Methods Probability proportionate to size sampling （PPS） was employed in the surveillance of IDD, for which a total of 1200 school children aged 8-10 years were randomly selected from 30 counties around the whole province during each IDD survey. The iodine content of salt was determined quantitatively with the titration method. The iodine content of urinary samples was measured by the method of ammonium persulfate oxidation. Results The coverage of iodized salt increased from 65.0% in 1995 to 98.0% in 1999, then decreased to 88.1% in 2005 which was below the national standard of 90%. The median urinary iodine of children aged 8-10 years varied between 160.1 μg/L and 307.4 μg/L, which was above the national standard. The proportion of urinary samples with iodine content above 300 lag/L was over 30% in 2005, implying exorbitant iodine nutrition among the children. The goiter rate （TGR） among children aged 8-10 years dropped from 11.8% in 1995 to 2.7% in 2005, indicating that the spread of endemic goiter was under control. Conclusion Preliminary elimination of IDD was achieved by USI in Hebei province. Nevertheless, some problems still existed in USI such as non-iodized salt competition, over iodization and un-standardized iodization. In order to address these problems, the management and supervision of salt market needs to be strengthened to prevent non-iodized salt from reaching households; updating equipment and modifying techniques are also necessary to ensure the quality of iodized salt; to clarify the causes of excessive urinary iodine content, the various sources of iodine from the diet need to be investigated in the future.

关键词： Iodine deficiency disorders (IDD) Universal salt iodization (USI) Assessment Effectiveness

Existence of Positive Solutions to a Fractional-Kirchhoff System

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Acta Mathematicae Applicatae Sinica 2024年第1期40卷 225-240页

作者： Peng-fei li jun-hui xie Dan Mu School of Mathematics and Statistics Hubei Minzu UniversityEnshi445000China

LetΩbe a bounded smooth domain in RN(N≥3).Assuming that 00 are constants,we consider the existence results for positive solutions of a class of fractional elliptic system below,{(a+b[u]^(2)_(s))(-Δ)^(s)u=vp+h_(1)(x,u,v,▽u,▽v),x∈Ω,(-Δ)^(s)v=u^(q)+h_(2)(x,u,▽,▽u,▽v),x∈Q,u,v>0,x∈Ω,u=v=0,x∈RN\Ω.Under some assumptions of hi(x,u,v,▽u,▽v)(i=1,2),we get a priori bounds of the positive solutions to the problem(1.1)by the blow-up methods and rescaling *** on these estimates and degree theory,we establish the existence of positive solutions to problem(1.1).

关键词： fractional-Kirchhoff system a priori bounds degree theory positive solution