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Temporal dynamics of nutrient balance, plasma biochemical and immune traits, and liver function in transition dairy cows

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Journal of Integrative Agriculture 2020年第3期19卷 820-837页

作者： SUN bo-fei CAO Yang-chun CAI Chuan-jiang YU Chao li Sheng-xiang YAO Jun-hu College of Animal Science and Technology Northwest A&F UniversityYangling 712100P.R.China The Development Centre of Animal Husbandry Bureau of Agriculture and Rural Affairs of ShangluoShangluo 726000P.R.China

The objective of this study was to analyze the dynamics of nutrient balance,physiological biomarkers and comprehensive indexes associated with metabolism and function of organs in transition *** transition cows were used for this *** intake was recorded daily,and samples of the diet,venous blood and milk were collected for *** balance values of net energy for lactation(NEL),metabolizable protein(MP),and metabolizable glucose(MG) were calculated,and regression analysis and calculation of comprehensive indexes were ***,the prepartum cows presented positive balances of NEL,MP,and MG,while severe negative balances were found during the postpartum *** changes of energy metabolism,nutrient mobilization,liver function,anti-oxidative status and immune response,as indicated by blood biomarkers and modified comprehensive indexes,were out of sync with the calculated balance values,but they were closely related to the day relative to *** with the 21 d prepartum,the plasma concentrations of non-esterified fatty acids(NEFA) and β-hydroxybutyric acid(BHBA) were significantly increased around and after calving(Plied before calving,because metabolic adaptations had been validated during the prepartum *** addition,it was plausible to conclude that the decline of hepatic metabolism,defense function and insulin sensitivity are critical causes of metabolic dysfunction.

关键词： transition dairy cow endocrine metabolism physiology regulation

Effects of epidermal growth factor receptor inhibitor on proliferative cholangitis in hepatolithiasis

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Hepatobiliary & Pancreatic Diseases International 2015年第5期14卷 509-515页

作者： Qin Yang Yong Zhou Fu-Yu li Hui mao Anuj Shrestha Wen-Jie Ma Nan-Sheng Cheng Wei Zhang Department of Hepatobiliary Surgery West China Hospital of Sichuan University Department of Medicine The George Washington University

BACKGROUND： There is currently no effective medication to prevent stone recurrence after choledochoscopic lithotomy or to treat proliferative cholangitis（PC）, which is the pathologic basis of hepatolithiasis. This study aimed to investigate whether gefitinib, an epidermal growth factor receptor（EGFR） inhibitor, inhibited cholangio hyperplasia and lithogenesis in ***： After cholangioscopic lithotomy, indwelling catheters were placed in the diseased bile duct lumens in 94 patients with hepatolithiasis. Subsequently, 49 of the 94 patients were treated with 250 mg gefitinib solution via a catheter twice a week, and they were subjected to choledochoscopic biopsy at 6 and 12 weeks. The rest 45 hepatolithiasis patients without gefitinib treatment served as ***： The expressions of EGFR, PCNA and procollagen I were significantly reduced in the patients treated with gefitinib in 12 weeks compared with those in the control group. Patients in the gefitinib group had a much lower degree of hyperplasia of the biliary epithelium, submucosal glands and collagen fibers compared with those in the control group. Gefitinib treatment significantly decreased mucin 3 expression and β-glucuronidase ***： Postoperative gefitinib treatment could significantly inhibit PC-mediated hyperplasia and lithogenesis, which might provide a novel strategy for the prevention of biliary restenosis and stone recurrence in patients with hepatolithiasis.

关键词： hepatolithiasis proliferative cholangitis epidermal growth factor receptor blockade recurrence restenosis prevention

Feasibility study on expanded indication for endoscopic submucosal dissection of intramucosal poorly differentiated early gastric cancer

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World Journal of Gastroenterology 2016年第29期22卷 6736-6741页

作者： Hua li Zhi-Bin Huo Shu-bo Chen Hui li Dian-Chao Wu Tong-Shan Zhai Qi-Hai Xiao Shu-Xia Wang li-li Zhang Department of Surgical Oncology Affiliated Xingtai People’s Hospital of Hebei Medial University Department of Surgical Urology Affiliated Xingtai People’s Hospital of Hebei Medial University Department of Hepatobiliary Surgery Affiliated Xingtai People’s Hospital of Hebei Medial University

AIM: To identify clinicopathological factors predictive of lymph node metastasis(LNM) in intramucosal poorly differentiated early gastric cancer(EGC), and further to expand the possibility of using endoscopic submucosal dissection(ESD) for the treatment of intramucosal poorly differentiated ***: Data for 81 surgically treated patients with intramucosal poorly differentiated EGC were collected, and the association between the clinicopathological factors and the presence of LNM was retrospectively analyzed by univariate and multivariate logistic regression analyses. Odds ratios(ORs) with 95% confidence intervals(CIs) were calculated. Several clinicopathologic factors were investigated to identify predictive factors for lymph nodes metastasis, including gender, age, family history of gastric cancer, number of tumors, tumor location, ulceration, tumor size, macroscopic type, lymphatic vessel involvement, and signet-ring-cell ***: Tumor size(OR = 7.273, 95%CI: 1.246-29.918, P = 0.042), lymphatic vessel involvement(OR = 42.219, 95%CI: 1.923-97.052, P = 0.018) and signet-ring-cell component(OR = 17.513, 95%CI: 1.647-77.469, P = 0.034) that were significantly associated with LNM by univariate analysis, were found to be significant and independent risk factors for LNM by multivariate analysis. However, gender, age, family history of gastric cancer, number, location, ulceration and macroscopic type of tumor were found not to be associated with LNM. Of these 81 patients diagnosed with intramucosal poorly differentiated EGC, 7(8.6%) had LNM. The LNM rates were 9.1%, 22.2% and 57.1%, respectively, in cases with one, two and three of the risk factors. There was no LNM in 54 patients without the three risk clinicopathological ***: Tumor size, lymphatic vessel involvement and signet-ring-cell component are independently associated with the presence of LNM in intramucosal poorly differentiated EGC. Thus, these three risk factors may be used as a

关键词： Intramucosal poorly differentiated early gastric cancer Early gastric cancer Clinicopathological characteristics Lymph node metastasis Endoscopic submucosal dissection

A Defense Planning Model for a Power System Against Coordinated Cyber-physical Attack

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Protection and Control of Modern Power Systems 2024年第5期9卷 84-95页

作者： Peiyun li Jian Fu Kaigui Xie bo Hu Yu Wang Changzheng Shao Yue Sun Wei Huang State Key Laboratory of Power Transmission Equipment&System Security and New Technology Chongqing UniversityChongqing 400044China State Grid Chengdu Power Supply Com-pany State Grid Sichuan Electric Power Co.Ltd.Chengdu 610041China China Yangtze Power Co. LtdYichang 443002China

This paper proposes a tri-level defense planning model to defend a power system against a coor-dinated cyber-physical attack(CCPA).The defense plan considers not only the standalone physical attack or the cyber attack,but also coordinated *** defense strategy adopts coordinated generation and transmission expansion planning to defend against the *** the process of modeling,the upper-level plan represents the perspective of the planner,aiming to minimize the critical load shedding of the planning system after the *** load resources available to planners are extended to flex-ible loads and critical *** middle-level plan is from the viewpoint of the attacker,and aims at generating an optimal CCPA scheme in the light of the planning strategy determined by the upper-level plan to maximize the load shedding caused by the *** optimal operational behavior of the operator is described by the lower-level plan,which minimizes the load shedding by defending against the *** tri-level model is analyzed by the column and constraint generation algorithm,which decomposes the defense model into a master problem and *** studies on a modified IEEE RTS-79 system are performed to demonstrate the economic effi-ciency of the proposed model.

关键词： Coordinated cyber-physical attack flexible load column-and-constraint generation defense planning robust optimization.

Study on the liquid membrane oscillation of water/oil/water system containing TTAB and picric acid

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Chinese Chemical Letters 2008年第7期19卷 871-876页

作者： li Zhou Jiao Ning Tang bo liu Yi Guang Wu Ai lian Wang Chuan Dong liao College of Chemistry and Chemical Engineering Shenzhen University Shenzhen 518060 China College of Materials Science and Engineering Shenzhen University Shenhen Key Laboratory of Special Functional Materials Shenzhen 518060 China

The liquid membrane oscillation of a novel water （aqueous tetradecyl trimethyl ammoniumbromide, TTAB and alcohol solution）/oil （picric acid in chloroform solution）/water （aqueous glucose solution） system was investigated. By using homemade device, the curves of various liquid membranes oscillation with different concentration of TTAB and picric acid, types of alcohol and other organic solvents at different temperature were measured. The results show that the water （aqueous 7 mmol/L of TTAB and 0.5 mol/L of n-propanol solution）/oil （0.5 mmol/L of picric acid in chloroform solution）/water （aqueous glucose solution） system performed sustained and stable oscillation at 30 ℃. And the novel system can recognise added amino acid.

关键词： liquid membrane Oscillation Surfactant Tetradecyl trimethyl ammoniumbromide (TTAB) Amino acid

Effect of dilute acid treatment on adhesion properties of Longmaxi black shale

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Petroleum Science 2019年第6期16卷 1320-1331页

作者： Pan-Pan Zhang Shou-Ceng Tian mao Sheng Tian-Yu Wang Waleed Ali Khan Quan Xu li-Zhi Xiao State Key Laboratory of Petroleum Resources and Prospecting China University of Petroleum(Beijing)Beijing 102249China Harvard SEAS-CUPB Joint Laboratory on Petroleum Science 29 Oxford StreetCambridgeMA 02138USA

Properties of shale in an acid environment are important when acid or CO2 is injected into geologic formations as a working fluid for enhanced oil and gas recovery,hydraulic fracturing and reduced fracture initiation *** has previously been shown that acid fluids can enhance the formation conductivity and decrease the hardness of ***,less is known about the effect of dilute acid on the adhesion properties of *** the study,shale samples are characterized in detail with advanced *** properties of shale via dilute acid treatment were revealed by atomic force microscopy(AFM)for the first *** indicate that acid treatment can greatly enhance adhesion forces of the shale *** acid treatment,the average adhesion forces show a platform-like growth with an increase in loading *** analysis of results from AFM,scanning electron microscopy,and X-ray diffraction,we affirm that the enhanced adhesion forces are mainly from increased specific surface area and reduced elastic *** results presented in this work help understand the adhesion properties of shale oil/gas present in an acidic environment,which have great significance in unconventional resources development.

关键词： Shale Acid Carbonates Atomic force microscope Adhesion force

Compressive near-field millimeter wave imaging algorithm based on Gini index and total variation mixed regularization

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Journal of Electronic Science and Technology 2023年第1期21卷 65-74页

作者： Jue Lyu Dong-Jie Bi bo liu Guo Yi Xue-Peng Zheng Xi-Feng li li-Biao Peng Yong-Le Xie Yi-Ming Zhang Ying-li Bai School of Automation Engineering University of Electronic Science and Technology of ChinaChengdu611731China Shanghai Spaceflight Precision Machinery Institute Shanghai201600China Electrical Engineering Department Northwestern UniversityEvanston60208USA Institute of Telecommunication Satellite China Academy of Space TechnologyBeijing100094China

A compressive near-field millimeter wave(MMW)imaging algorithm is *** the compressed sensing(CS)theory,the compressive near-field MMW imaging process can be considered to reconstruct an image from the under-sampled sparse *** Gini index(GI)has been founded that it is the only sparsity measure that has all sparsity attributes that are called Robin Hood,Scaling,Rising Tide,Cloning,Bill Gates,and *** combining the total variation(TV)operator,the GI-TV mixed regularization introduced compressive near-field MMW imaging model is *** addition,the corresponding algorithm based on a primal-dual framework is also *** results demonstrate that the proposed GI-TV mixed regularization algorithm has superior convergence and stability performance compared with the widely used l1-TV mixed regularization algorithm.

关键词： Millimeter wave(MMW) Compressed sensing(CS) Gini index(GI) Total variation(TV) Signal processing Image reconstruction

Polarization Mechanism of Oxygen Vacancy and Its Influence on Dielectric Properties in ZnO

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Chinese Physics Letters 2011年第2期28卷 179-182页

作者： WANG li-Na FANG Xiao-Yong HOU Zhi-ling li Ya-lin WANG Kun YUAN Jie CAO mao-Sheng School of Science Yanshan UniversityQinhuangdao 066004 School of Materials Science and Engineering Beijing Institute of TechnologyBeijing 100081 School of Information Engineering Central University for NationalitiesBeijing 100081

We report on the mechanism of the dielectric properties of oxygen vacancy in ZnO,using ab initio numerical simulations of oxygen vacancy on the band structure and dielectric properties,to develop photoelectric material *** is revealed that the appearance of oxygen vacancies leads to wider energy band gap,obvious blue shift and increase in the peak of dielectric function as compared to the intrinsic ZnO *** explain these unusual phenomena and analyze the dielectric changes with the mechanism of polarization in the *** is shown that the main mechanism of influencing dielectric properties is the electron displacement *** result may be helpful for development of photoelectric materials.

关键词： materials dielectric vacancy

Bridged Effects of Various Heterocyclic linkages in Bis-1,2,4-triazoles

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Chinese Journal of Structural Chemistry 2021年第11期40卷 1433-1438,1405页

作者： WU Jin-Ting XU Jin li Hong-bo ZHANG Jian-Guo School of Materials Science and Engineering Southwest University of Science and TechnologyMianyang 621010China State Key Laboratory of Explosion Science and Technology Beijing Institute of TechnologyBeijing 100081China

There are numerous studies on nitrogen-rich heterocycles explosive design and synthesis due to their good detonation activity.A series of bistriazoles with different heterocyclic linkages were designed and calculated by density functional theory(DFT)b3 lyp/6-311+G^(*)*** structure,detonation properties and stability of the energetic compounds have been *** to the results from heats of formation(HOFs),the HOF values of bistriazole with heterocycle linkage(M1~M4)are higher than those of the corresponding diamino-heterocycle bridged ones(M5~M8).By analyzing the bond dissociation energy(BDE),-NH-is not conducive to increase the stability of the *** terms of detonation performances and stability of bistriazole derivatives,the combination of furazan or tetrazole linkages with bis-triazoles may be considered as potential candidates for energetic materials.

关键词： density functional theory effect of heterocyclic linkage energetic material detonation performance