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施工技术 2011年第14期40卷 64-65页

作者：李珠袁波赵林太原理工大学建筑与土木工程学院

通过阐述玻化微珠保温砂浆的性能,并对外保温系统进行了防火安全分析,证明了玻化微珠保温少浆作为防火隔离带的可行性,可有效阻止外墙外保温系统的火势蔓延。同时提出了该防火隔离带的设计方法。

关键词：玻化微珠保温砂浆防火隔离带设计方法

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土壤氟形态与氟污染土壤修复

应用生态学报 2019年第1期30卷 10-20页

作者：袁立竹王加宁马春阳郭书海山东省科学院生态研究所济南250013 中国科学院沈阳应用生态研究所沈阳110016 扎鲁特旗环境监测站内蒙古通辽029100

我国土壤氟污染问题严峻,给部分地区人体健康和生态安全造成严重威胁,但土壤氟污染与防治问题仍没有受到人们的广泛关注.本文概述了土壤中氟的存在形态以及发生的主要化学反应,综述了近年来国内外有关氟污染土壤修复的研究进展,提出了... 详细信息

我国土壤氟污染问题严峻,给部分地区人体健康和生态安全造成严重威胁,但土壤氟污染与防治问题仍没有受到人们的广泛关注.本文概述了土壤中氟的存在形态以及发生的主要化学反应,综述了近年来国内外有关氟污染土壤修复的研究进展,提出了今后氟污染土壤修复的研究方向,以期为氟污染土壤的修复提供借鉴和参考.土壤中氟主要分为5种形态,其中90%以上以残渣态存在,土壤溶液中的氟主要发生沉淀-溶解、络合-解离和吸附-解吸等反应来维持水-土系统中的氟平衡.目前,氟污染土壤修复技术研究主要集中在化学固定修复技术、化学淋洗技术、电动修复技术以及植物修复技术.今后需要重点研究氟在土壤中的赋存形态及其影响因子,筛选功能微生物和植物,开发联合修复技术以修复氟污染土壤.

关键词：土壤氟赋存形态修复技术

Solar flare forecasting based on a Fusion Model

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Earth and Planetary Physics 2025年第1期9卷 171-181页

作者： YiYang li ShiYong Huang SiBo Xu ZhiGang yuan Kui Jiang QiYang Xiong RenTong lin School of Earth and Space Science Technology Hubei Luojia LaboratoryWuhan UniversityWuhan 430072China

Solar flare prediction is an important subject in the field of space *** learning technology has greatly promoted the development of this *** this study,we propose a novel solar flare forecasting model integrating Deep Residual Network(ResNet)and Support Vector Machine(SVM)for both≥C-class(C,M,and X classes)and≥M-class(M and X classes)*** collected samples of magnetograms from May 1,2010 to September 13,2018 from Space-weather Helioseismic and Magnetic Imager(HMI)Active Region Patches and then used a cross-validation method to obtain seven independent data *** then utilized five metrics to evaluate our fusion model,based on intermediate-output extracted by ResNet and SVM using the Gaussian kernel *** results show that the primary metric true skill statistics(TSS)achieves a value of 0.708±0.027 for≥C-class prediction,and of 0.758±0.042 for≥M-class prediction;these values indicate that our approach performs significantly better than those of previous *** metrics of our fusion model’s performance on the seven datasets indicate that the model is quite stable and robust,suggesting that fusion models that integrate an excellent baseline network with SVM can achieve improved performance in solar flare ***,we also discuss the performance impact of architectural innovation in our fusion model.

关键词： solar flare pace weather deep learning Fusion Model

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中西医结合治疗创伤性大面积头皮缺损

中华神经医学杂志 2005年第4期4卷 408-410页

作者：李元柱李文东天津市蓟县人民医院神经外科 301900

目的探讨中西医结合治疗创伤性大面积头皮缺损的效果。方法早期西医方法治疗,中后期完全用中医方法换药、植皮等。结果6例病人均顺利治愈。结论该方法适合于创伤性大面积头皮缺损的治疗,其优点是方法简洁、病程短、痛苦小、费用低、无... 详细信息

目的探讨中西医结合治疗创伤性大面积头皮缺损的效果。方法早期西医方法治疗,中后期完全用中医方法换药、植皮等。结果6例病人均顺利治愈。结论该方法适合于创伤性大面积头皮缺损的治疗,其优点是方法简洁、病程短、痛苦小、费用低、无副作用。

关键词：大面积头皮缺损中西医结合治疗创伤性中医方法无副作用中后期

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髓母细胞瘤在脑和脊髓同时多发一例

中华神经医学杂志 2005年第3期4卷 293-294页

作者：李元柱李文东天津市蓟县人民医院神经外科 301900

患者,男,8岁.于住院前10 d出现头疼,并进行性加重;同时双下肢无力,左侧重,跛行.在当地予对症用药治疗无效,于1995年12月4日收住我科.查体:全身一般检查未见异常.神经系统检查:神志清楚,语言流利,答话切题,合作好,表情淡漠.双眼左侧视野... 详细信息

患者,男,8岁.于住院前10 d出现头疼,并进行性加重;同时双下肢无力,左侧重,跛行.在当地予对症用药治疗无效,于1995年12月4日收住我科.查体:全身一般检查未见异常.神经系统检查:神志清楚,语言流利,答话切题,合作好,表情淡漠.双眼左侧视野缺损,余颅神经正常.颈部强硬,双侧克尼格征(+).双侧巴彬斯基征(+).四肢肌力:双上肢V级,左下肢Ⅲ级,右下肢Ⅳ级。

关键词：髓母细胞瘤多发脊髓神经系统检查 95年12月进行性加重双下肢无力巴彬斯基征用药治疗视野缺损脑住院前颅神经双上肢左下肢右下肢左侧双侧

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特大骨瓣减压治疗特重型颅脑损伤

中华神经医学杂志 2005年第1期4卷 71-73页

作者：李元柱李文东天津市蓟县人民医院神经外科 301900

目的评估实施特大骨瓣减压术治疗特重型颅脑损伤的手术适应证及疗效.方法对50例特重型颅脑损伤患者均实施了特大骨瓣减压术.结果按格拉斯哥预后评分(GOS):恢复0例,良好2例,中残8例,重残21例,植物生存6例,死亡13例.37例存活者出院后随访1... 详细信息

目的评估实施特大骨瓣减压术治疗特重型颅脑损伤的手术适应证及疗效.方法对50例特重型颅脑损伤患者均实施了特大骨瓣减压术.结果按格拉斯哥预后评分(GOS):恢复0例,良好2例,中残8例,重残21例,植物生存6例,死亡13例.37例存活者出院后随访1～4年,再次GOS评定:恢复2例,良好5例,中残10例,重残10例,植物生存3例,死亡7例.共死亡20例,总死亡率40%.结论对特重型颅脑损伤实施特大骨瓣减压术是挽救该类垂危病人的首选办法.在严格掌握手术适应证的同时,确定、实施适当手术方案,并减张缝合修复硬膜,是值得提倡的手术措施,辅以术后常规治疗,可明显提高疗效.

关键词：治疗特重型颅脑损伤大骨瓣减压术 GOS 死亡手术适应证疗效植物生存恢复

3D Printing of Tough Hydrogel Scaffolds with Functional Surface Structures for Tissue Regeneration

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Nano-Micro Letters 2025年第2期17卷 18-45页

作者： Ke Yao Gaoying Hong Ximin yuan Weicheng Kong Pengcheng Xia yuanrong li Yuewei Chen Nian liu Jing He Jue Shi Zihe Hu Yanyan Zhou Zhijian Xie Yong He State Key Laboratory of Fluid Power and Mechatronic Systems School of Mechanical EngineeringZhejiang UniversityHangzhou 310027People’s Republic of China liangzhu Laboratory Zhejiang UniversityHangzhou 310027People’s Republic of China Key Laboratory of 3D Printing Process and Equipment of Zhejiang Province College of Mechanical EngineeringZhejiang UniversityHangzhou 310027People’s Republic of China Stomatology Hospital School of StomatologyZhejiang University School of MedicineHangzhou 310027People’s Republic of China State Key Laboratory of Advanced Welding and Joining Harbin Institute of TechnologyHarbin 150001People’s Republic of China Institute of Digital Medicine Nanjing First HospitalNanjing Medical UniversityNanjing 210006People’s Republic of China

Hydrogel scaffolds have numerous potential applications in the tissue engineering ***,tough hydrogel scaffolds implanted in vivo are seldom reported because it is difficult to balance biocompatibility and high mechanical *** by Chinese ramen,we propose a universal fabricating method(printing-P,training-T,cross-linking-C,PTC&PCT)for tough hydrogel scaffolds to fill this ***,3D printing fabricates a hydrogel scaffold with desired structures(P).Then,the scaffold could have extraordinarily high mechanical properties and functional surface structure by cycle mechanical training with salting-out assistance(T).Finally,the training results are fixed by photo-cross-linking processing(C).The tough gelatin hydrogel scaffolds exhibit excellent tensile strength of 6.66 MPa(622-fold untreated)and have excellent ***,this scaffold possesses functional surface structures from nanometer to micron to millimeter,which can efficiently induce directional cell ***,this strategy can produce bionic human tissue with mechanical properties of 10 kPa-10 MPa by changing the type of salt,and many hydrogels,such as gelatin and silk,could be improved with PTC or PCT *** experiments show that this scaffold can effectively promote the new generation of muscle fibers,blood vessels,and nerves within 4 weeks,prompting the rapid regeneration of large-volume muscle loss injuries.

关键词： 3D printing Tough hydrogel scaffold Functional surface structure Tissue regeneration Biomaterials

The compound(E)-2-(3,4-dihydroxystyryl)-3-hydroxy-4H-pyran-4-one alleviates neuroinflammation and cognitive impairment in a mouse model of Alzheimer's disease

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Neural Regeneration Research 2025年第11期20卷 3330-3344页

作者： Xueyan liu Wei Wu Xuejuan li Chengyan Wang Ke Chai Fanru yuan Huijuan Zheng Yuxing Yao Chenlu li Zu-Cheng Ye Daijun Zha Department of Medicinal Chemistry School of PharmacyFujian Medical UniversityFuzhouFujian ProvinceChina Fujian Provincial Key Laboratory of Brain Aging and Neurodegenerative Diseases School of Basic Medical SciencesFujian Medical UniversityFuzhouFujian ProvinceChina Institute of Laboratory Animal Center Fujian Medical UniversityFuzhouFujian ProvinceChina Department of Neurosurgery Neurosurgery Research InstituteThe First Affiliated HospitalFujian Medical UniversityFuzhouFujian ProvinceChina Department of Hyperbaric Oxygen National Regional Medical CenterBinhai Campus of the First Affiliated HospitalFujian Medical UniversityFuzhouFujian ProvinceChina

Previous studies have shown that the compound(E)-2-(3,4-dihydroxystyryl)-3-hydroxy-4H-pyran-4-one(D30),a pyromeconic acid derivative,possesses antioxidant and anti-inflammatory properties,inhibits amyloid-β aggregation,and alleviates scopolamine-induced cognitive impairment,similar to the phase Ⅲ clinical drug *** this study,we established a mouse model of Alzheimer's disease via intracerebroventricular injection of fibrillar amyloid-β to investigate the effect of D30 on fibrillar amyloid-β-induced *** results showed that D30 alleviated fibrillar amyloid-β-induced cognitive impairment,promoted fibrillar amyloid-β clearance from the hippocampus and cortex,suppressed oxidative stress,and inhibited activation of microglia and astrocytes.D30 also reversed the fibrillar amyloid-β-induced loss of dendritic spines and synaptic protein ***,we demonstrated that exogenous fibrillar amyloid-βintroduced by intracerebroventricular injection greatly increased galectin-3 expression levels in the brain,and this increase was blocked by *** the role of D30 in clearing amyloid-β,inhibiting neuroinflammation,protecting synapses,and improving cognition,this study highlights the potential of galectin-3 as a promising treatment target for patients with Alzheimer's disease.

关键词： Alzheimer's disease amyloid-β astrocyte cognitive impairment D30 dendritic spines galectin-3 microglia neuroinflammation neuron

High-dose dexamethasone regulates microglial polarization via the GR/JAK1/STAT3 signaling pathway after traumatic brain injury

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Neural Regeneration Research 2025年第9期20卷 2611-2623页

作者： Mengshi Yang Miao Bai yuan zhuang Shenghua Lu Qianqian Ge Hao li Yu Deng Hongbin Wu Xiaojian Xu Fei Niu Xinlong Dong Bin Zhang Baiyun liu Beijing Tiantan Hospital Capital Medical UniversityBeijingChina Department of Neurology The First Hospital of Tsinghua UniversityBeijingChina Department of Neurotrauma and Beijing Key Laboratory of Central Nervous System Injury Beijing Neurosurgical InstituteCapital Medical UniversityBeijingChina Department of Critical Care Medicine Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Center for Nerve Injury and Repair Beijing Institute of Brain DisordersChina National Clinical Research Center for Neurological DiseasesBeijingChina

Although microglial polarization and neuroinflammation are crucial cellular responses after traumatic brain injury,the fundamental regulatory and functional mechanisms remain insufficiently *** potent anti-inflammato ry agents,the use of glucoco rticoids in traumatic brain injury is still controversial,and their regulatory effects on microglial polarization are not yet *** the present study,we sought to determine whether exacerbation of traumatic brain injury caused by high-dose dexamethasone is related to its regulatory effects on microglial polarization and its mechanisms of *** vitro cultured BV2 cells and primary microglia and a controlled cortical impact mouse model were used to investigate the effects of dexamethasone on microglial ***,dexamethasone,RU486(a glucocorticoid receptor antagonist),and ruxolitinib(a Janus kinase 1 antagonist)were ***-sequencing data obtained from a C57BL/6 mouse model of traumatic brain injury were used to identify potential targets of *** Morris water maze,quantitative reverse transcription-polymerase chain reaction,western blotting,immunofluorescence and confocal microscopy analysis,and TUNEL,Nissl,and Golgi staining were performed to investigate our ***-throughput sequencing results showed that arginase 1,a marker of M2 microglia,was significantly downregulated in the dexamethasone group compared with the traumatic brain injury group at3 days post-traumatic brain *** dexamethasone inhibited M1 and M2 microglia,with a more pronounced inhibitory effect on M2microglia in vitro and in *** receptor plays an indispensable role in microglial polarization after dexamethasone treatment following traumatic brain ***,glucocorticoid receptor activation increased the number of apoptotic cells and neuronal death,and also decreased the density of dendritic spines.A possible downstream receptor signaling mechanism is th

关键词： apoptosis BV2 microglia dexamethasone glucocorticoid receptor glucocorticoids innate immune system microglial polarization neuroinflammation primary microglia traumatic brain injury

Multi-source and multi-temporal remote sensing image classification for flood disaster monitoring

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Global Geology 2025年

作者： li zhu JIA Zhenyang DONG Jing liU Zhenghong College of Earth Sciences Jilin University Dandong No.2 High School

Flood disasters can have a serious impact on people's production and lives, and can cause huge ***-sourceremotesensingdata,thisstudyestablished decision tree classification rules through multi-source and multi-temporal feature fusion, classified ground objects before the disaster and extracted flood information in the disaster area based on optical images during the disaster, so as to achieve rapid acquisition of the disaster situation of each disaster bearing *** the case of Qianliang Lake, which suffered from flooding in 2020, the results show that decision tree classification algorithms based on multi-temporal features can effectively integrate multi-temporal and multispectral information to overcome the shortcomings of single-temporal image classification and achieve ground-truth object classification.

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