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一种可量化评价的温针灸实训教学仪的研制与实践

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针刺研究 2024年第1期49卷 99-102页

作者：徐刚高明刘堂义唐文超温军玲李少雄上海中医药大学针灸推拿学院上海201203

通过总结传统温针灸技术操作关键步骤和要点,确定评价温针灸操作过程的量化参数指标,在此基础上研制温针灸实训教学仪,并应用于实训课程教学。实践表明,温针灸实训教学仪可量化温针灸技术操作过程中的搓装艾绒速度、搓装艾绒个数、抗抖... 详细信息

通过总结传统温针灸技术操作关键步骤和要点,确定评价温针灸操作过程的量化参数指标,在此基础上研制温针灸实训教学仪,并应用于实训课程教学。实践表明,温针灸实训教学仪可量化温针灸技术操作过程中的搓装艾绒速度、搓装艾绒个数、抗抖动时间、抗抖动频率和艾绒团燃烧时间等参数,客观评价温针灸操作技术熟练程度和搓装艾绒团的效果,同时也提出了后续研究工作的完善思路。温针灸实训教学仪的研制与实践应用,有利于培养学生实操的规范性、准确性,对促进温针灸教学及考核方法的客观化和教学手段的多样化具有十分重要的意义,同时可对其他针灸技术的实训教学起到示范作用。

关键词：温针灸技术操作规范化实训教学评价

花生含油量全基因组选择及近红外光谱筛选的育种技术探究

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作物学报 2024年第4期50卷 969-980页

作者：鲁清刘浩李海芬王润风黄璐梁炫强陈小平洪彦彬刘海燕李少雄广东省农业科学院作物研究所/广东省农作物遗传改良重点实验室/国家油料作物改良中心南方花生分中心广东广州510640

花生含油量对单位面积产油量至关重要。该性状受多个微效基因控制,但可用的紧密连锁标记十分有限,传统的分子标记辅助选择育种准确性不高。全基因组选择作为一种新的育种方法,可实现对数量性状的早期预测;近红外光谱分析可对作物品质性... 详细信息

花生含油量对单位面积产油量至关重要。该性状受多个微效基因控制,但可用的紧密连锁标记十分有限,传统的分子标记辅助选择育种准确性不高。全基因组选择作为一种新的育种方法,可实现对数量性状的早期预测;近红外光谱分析可对作物品质性状(如含油量等)进行无损检测。通过两者优势互补,建立花生含油量全基因组选择和近红外光谱筛选联合的育种技术,探讨影响花生含油量全基因组选择预测准确性的因素,为花生分子育种奠定理论基础。本研究以216个重组自交系为材料构建训练群体;分别以139、464和505株F_(2)、F_(3)和F_(4)为材料构建育种群体;利用自主开发的“PeanutGBTS40K”液相芯片进行基因分型,开展含油量全基因组选择育种模型分析;通过联合全基因组选择和近红外光谱筛选技术,开展花生含油量性状的育种应用,并评价其育种效果。结果显示,对训练群体进行基因分型后,总共获得30,355个高质量SNPs,并用于11个全基因组预测的模型选择分析。含油量预测准确性最高的模型为rrBLUP,其次是randomforest和svmrbf。以重组自交系为预测群体,F_(2)、F_(3)和F_(4)各世代含油量的预测准确性分别为0.116、0.128和0.119;以重组自交系叠加上一轮的育种群体为预测群体,各世代含油量的预测准确性分别为0.116、0.131和0.160。全基因组选择联合近红外筛选要比单独的全基因组选择对各世代的含油量选择效果提高1.8%、2.7%和3.4%;与单独的近红外筛选相比,差异不显著(0.10%、0.06%和0.07%);而近红外筛选与全基因组选择相比,含油量可显著提高1.7%、2.6%和3.3%。通过联合全基因组选择和近红外光谱筛选育种,F_(3)和F_(4)分别比F_(2)的含油量提高1.2%和1.0%。F_(4)总共获得16个入选改良株系,有10个株系含油量≥55.0%,其中2个株系(SF_(4)_201和SF_(4)_379)的理论产量分别比对照增产7.0%和11.1%。本研究通过建立花生含油量性状的全基因组选择-近红外光谱筛选联合育种技术,可有效实现花生含油量性状的遗传改良。

关键词：花生含油量全基因组选择近红外光谱分析基因组育种值

Power Law Behavior of the Zero Bias Tunneling Conductance:the New Evidence for d-Wave Symmetry

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Chinese Physics Letters 2000年第10期17卷 760-761页

作者： li shao-xiong TAO Hong-Jie XUAN Yi ZHAO Bai-Ru ZHAO Zhong-Xian National Laboratory for Superconductivity Institute of Physics and Center for Condensed Matter PhysicsChinese Academy of SciencesBeijing 100080

We report temperature-dependent behavior of the zero bias tunneling conductance(ZBTC),derived from tun neling spectroscopies on as-grown Bi_(2)Sr_(2)CaCu_(2)O_(8+δ)(Bi2212)single crystals taken with evaporated Zn and Pb planar *** Tc the measured ZBTC shows a kink which gives an in situ measure of the superconducting transition temperature(T_(c)).Below T_(c),the T^(2)dependence of the ZBTC has been observed repeatedly as a new evidence of the d-wave symmetry in Bi2212.

关键词： ZBT Bi2212 Tunnel

耳穴刺激结合高频重复经颅磁刺激及吞咽训练改善脑卒中后吞咽障碍的研究

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中国处方药 2024年第1期22卷 179-182页

作者：杨小雯苏辉李少雄陈志标杜道兵石冰梁少霞中山市石岐苏华赞医院康复科广东中山528400

目的探讨耳穴刺激结合高频重复经颅磁刺激(rTMS)及吞咽训练改善脑卒中后吞咽障碍的临床效果。方法选取2021年1月~2022年2月收治的76例脑卒中后吞咽障碍患者,随机数字表法分为试验组(耳穴刺激+高频rTMS+吞咽训练,38例)和对照组(单纯吞咽... 详细信息

目的探讨耳穴刺激结合高频重复经颅磁刺激(rTMS)及吞咽训练改善脑卒中后吞咽障碍的临床效果。方法选取2021年1月~2022年2月收治的76例脑卒中后吞咽障碍患者,随机数字表法分为试验组(耳穴刺激+高频rTMS+吞咽训练,38例)和对照组(单纯吞咽训练,38例)。干预前后,以标准吞咽功能评价量表(SSA)评价两组吞咽功能,予以两组电视透视吞咽功能检查(VFSS),评价干预效果。结果试验组干预后SSA得分低于本组干预前与对照组干预后,VFSS得分高于本组干预前与对照组干预后,差异有统计学意义(P<0.05)。对照组干预后SSA低于干预前,VFSS评分高于干预前,差异有统计学意义(P<0.05)。试验组治疗总有效率高于对照组,差异有统计学意义(P<0.05)。结论脑卒中后吞咽障碍患者在吞咽训练基础上联合高频rTMS和耳穴刺激治疗,三者联用可以发挥协同作用,能够进一步强化临床疗效,更好地促进患者吞咽功能恢复。

关键词：脑卒中吞咽障碍耳穴刺激高频重复经颅磁刺激吞咽训练

Probing the interseismic locking state of the Xianshuihe fault based on a viscoelastic deformation model

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Science China Earth Sciences 2024年第1期67卷 134-145页

作者： Yage ZHU Faqi DIAO Fei CHEN Yuebing WANG Zhigang shao Rongjiang WANG xiong xiong Hubei Subsurface Multi-Scale Imaging Key Laboratory School of Geophysics and GeomaticsChina University of GeosciencesWuhan 430074China China Earthquake Networks Center Beijing 100045China Institute of Earthquake Forecasting China Earthquake AdministrationBeijing 100036China

The interseismic locking state of tectonic faults is essential for regional seismic hazard ***,it is challenging to obtain this parameter reliably due to the weak deformation and complex model *** better probe the fault locking state,more reliable physical models and well-covered observations are *** we investigate the locking state of the Xianshuihe fault based on a new-developed viscoelastic deformation ***,we combine GPS velocities from 13 new near-field stations and existing stations in this region to improve the spatial *** to the theoretical predictions,our results indicate that the elastic model will clearly overestimate the fault locking depth and seismic moment accumulation rate,and the fault slip rate inferred from the elastic model is slightly lower than that from the viscoelastic *** on the locking distribution inferred from the viscoelastic model,we identify four potential asperities on the Xianshuihe *** importantly,we find a clear spatial correlation between the fault locking distribution and the rupture extent of historical earthquakes,which indicates that the fault locking state may control the rupture extent and thus the magnitude of *** addition,our results show that the 2022 M6.8 Luding earthquake only ruptured the south part of a potential asperity,and the accumulated energy in the northern unruptured area is equivalent to an Mw6.9 earthquake,where the seismic hazard deserves special attention.

关键词： Fault kinematics Viscoelastic relaxation effect GPS observations Seismic hazard The 2022 M6.8 Luding earthquake

Improvement of impact properties of Al-Si-Mg alloy via solution treatment and joint modification with Sr and La

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Rare Metals 2024年第7期43卷 3301-3313页

作者： xiong-ling Zheng shao-Xiang li Jia-Le Ma Qing-Yan Xu Hai-Dong Zhao Zhi-Qiang Han Key Laboratory for Advanced Materials Processing Technology Ministry of EducationSchool of Materials Science and EngineeringTsinghua UniversityBeijing 100084China National Engineering Research Center of Near-Net Shape Forming for Metallic Materials South China University of TechnologyGuangzhou 510641China

An effort to obtain superior impact properties for Al-7Si-0.35 Mg alloy is presented,where modification with 0.02 wt% Sr and 0.1 wt% La as well as solution treatment was jointly *** samples were solution treated at 535℃ for 15 min to 12 *** microstructure,fracture mechanism,and their correlation with the impact properties of the alloy were studied in detail mainly through optical microscopy(OM),scanning electron microscopy(SEM) and oscillography impact *** results show that the addition of Sr and La refined the eutectic Si particles significantly from~ 2.05 μm(modified with Sr alone) to~ 0.75 μm in as-cast microstructure,leading to a very homogeneous distribution of spheroidized Si particles in the alloy solution treated at 535℃ for 8 *** alloy exhibits excellent impact toughness up to 75 J·cm^(-2),which is much higher than the maximum impact toughness of the alloys modified by Sr alone(~ 46 J·cm^(-2)).The major reason for this remarkable increase in the impact property is the dramatic increase in crack initiation *** dispersoid-free zones(DFZs)near the eutectic regions mainly consist of the ductile Al-matrix,which exhibits excellent *** ductile Al-matrix of the DFZs hinders the crack propagation,resulting in a significant increase in crack propagation energy.

关键词： Aluminum alloys Modification Solution treatment Microstructure Impact properties Fracture mechanism

Construction of Genetic linkage Map Based on SSR Markers in Peanut(Arachis hypogaea L.)

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Agricultural Sciences in China 2008年第8期7卷 915-921页

作者： HONG Yan-bin liANG Xuan-qiang CHEN Xiao-ping liU Hai-yan ZHOU Gui-yuan li shao-xiong WEN Shi-jie Crops Research Institute Guangdong Academy of Agricultural Sciences Guangzhou 510640 P.R.China

Molecular genetic maps of crop species can be used in a variety of ways in breeding and genomic research such as identification and mapping of genes and quantitative trait loci （QTLs） for morphological, physiological and economic traits of crop species. However, a comprehensive genetic linkage map for cultivated peanut has not yet been developed due to the extremely low frequency of DNA polymorphism in cultivated peanut. In this study, 142 recombinant inbred lines （RILs） derived from a cross between Yueyou 13 and Zhenzhuhei were used as mapping population in peanut （Arachis hypogaea L.）. A total 652 pairs of genomic-SSR primer and 392 pairs of EST-SSR primer were used to detect the polymorphisms between the two parents. 141 SSR primer pairs, 127 genomic-SSR and 14 EST-SSR ones, which can be used to detect polymorphisms between the two parents, were selected to analyze the RILs population. Thus, a linkage genetic map which consists of 131 SSR loci in 20 linkage groups, with a coverage of 679 cM and an average of 6.12 cM of inter-maker distance was constructed. The putative functions of 12 EST-SSR markers located on the map were analyzed. Eleven showed homology to gene sequences deposited in GenBank. This is the first report of construction of a comprehensive genetic map with SSR markers in peanut （Arachis hypogaea L.）. The map presented here will provide a genetic framework for mapping the qualitative and quantitative trait in peanut.

关键词： peanut (Arachis hypogaea L.) SSR genetic linkage map

Multi-Objective Multi-Variable Large-Size Fan Aerodynamic Optimization by Using Multi-Model Ensemble Optimization Algorithm

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Journal of Thermal Science 2024年第3期33卷 914-930页

作者： xiong Jin GUO Penghua li Jingyin School of Energy and Power Engineering Xi’an Jiaotong UniversityXi’an710049China

The constrained multi-objective multi-variable optimization of fans usually needs a great deal of computational fluid dynamics(CFD)calculations and is *** this study,a new multi-model ensemble optimization algorithm is proposed to tackle such an expensive optimization *** multi-variable and multi-objective optimization are conducted with a new flexible multi-objective infill *** addition,the search direction is determined by the multi-model ensemble assisted evolutionary algorithm and the feature extraction by the principal component analysis is used to reduce the dimension of optimization ***,the proposed algorithm and other two optimization algorithms which prevail in fan optimizations were compared by using test *** the same number of objective function evaluations,the proposed algorithm shows a fast convergency rate on finding the optimal objective function ***,this algorithm was used to optimize the rotor and stator blades of a large axial fan,with the efficiencies as the objectives at three flow rates,the high,the design and the low flow ***-two variables were included in the optimization *** results show that compared with the prototype fan,the total pressure efficiencies of the optimized fan at the high,the design and the low flow rate were increased by 3.35%,3.07%and 2.89%,respectively,after CFD simulations for 500 fan candidates with the constraint for the design *** optimization results validate the effectiveness and feasibility of the proposed algorithm.

关键词： multi-objective optimization surrogate-assisted evolutionary algorithm axial fan computational fluid dynamics aerodynamic optimization

Convex-up Style of Deformation within Grabens in Regions of Incomplete Crossing Conjugate Normal Faults: A Numerical Simulation Investigation and Case Study

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Journal of Earth Science 2024年第3期35卷 839-849页

作者： Zheng li Kai Wang xiong xiong Bing Zhou School of Geophysics and Geomatics China University of GeosciencesWuhan 430074China State Key Laboratory of Geodesy and Earth’s Dynamics Innovation Academy for Precision Measurement Science and TechnologyChinese Academy of SciencesWuhan 430077China Department of Earth Sicences Khalifa UniversityAbu DhabiUnited Arab Emirates

Crossing conjugate normal faults(CCNFs)are extensively developed in many hydrocarbon-producing basins,generally existing in the form of incomplete ***,the effect of the non-conjugate zone of the CCNFs on the conjugate relay zone post late tectonic action has not been previously *** use 3D elastic-plastic modeling to investigate the influence of incomplete(i.e.,partially intersecting)CCNFs on the pattern of deformation of strata in the intersection region.A series of model simulations were performed to examine the effects of horizontal tectonic extension,fault size,and fault depth on the deformation of conjugate relay zones of incomplete *** analyses yielded the following results.(1)The model of incomplete conjugation predicts a convex-up style of deformation in the conjugate graben region superimposed on overall subsidence under applied horizontal tectonic extension.(2)The degree of convex-up deformation of the conjugate graben depends on the influence of the non-conjugate zone on the conjugate relay zone,which varies with the amount of horizontal tectonic extension,fault size,and fault burial depth.(3)Our results indicate that incomplete CCNFs can form convex-up deformation,similar to that in the Nanpu Sag area and provide a sound understanding of hydrocarbon migration and accumulation.

关键词： incomplete conjugate normal fault conjugate graben convex-up deformation hydrocarbons Nanpu Sag tectonics.