检索结果-南通市图书馆

A novel metal-free porous covalent organic polymer for efficient room-temperature photocatalytic CO2 reduction via dry-reforming of methane

在线全文

学校读者我要写书评

暂无评论

Green Energy & Environment 2024年第9期9卷 1407-1418页

作者： Sheng-Yan Yin Ziyi li Yingcai hu Xiao Luo Jishan li College of Chemistry and Chemical Engineering Hunan University Institute of Basic Medicine and Cancer (IBMC) Chinese Academy of Sciences

At room temperature,the conversion of greenhouse gases into valuable chemicals using metal-free catalysts for dry reforming of methane（DRM） is quite promising and ***,we developed a novel covalent organic porous polymer （TPE-COP） with rapid charge separation of the electron–hole pairs for DRM driven by visible light at room temperature,which can efficiently generate syngas （CO and H2）.Both electron donor (tris（4-aminophenyl）amine,TAPA) and acceptor (4,4',4'',4'''-(（1 E,1'E,1''E,1'''E）-(ethene-1,1,2,2-tetrayltetrakis （benzene-4,1-diyl）)tetrakis （ethene-2,1-diyl）)tetrakis (1-（4-formylbenzyl）quinolin-1-ium),TPE-CHO) were existed in TPE-COP,in which the push–pull effect between them promoted the separation of photogenerated electron–hole,thus greatly improving the photocatalytic *** functional theory （DFT） simulation results show that TPE-COP can form charge-separating species under light irradiation,leading to electrons accumulation in TPE-CHO unit and holes in TAPA,and thus efficiently initiating *** 20 h illumination,the photocatalytic results show that the yields reach 1123.6 and 30.8μmol g-1for CO and H2,respectively,which are significantly higher than those of TPE-CHO small *** excellent result is mainly due to the increase of specific surface area,the enhancement of light absorption capacity,and the improvement of photoelectron-generating efficiency after the formation of ***,this work contributes to understanding the advantages of COP materials for photocatalysis and fundamentally pushes metal-free catalysts into the door of DRM field.

关键词： Metal-free Photocatalytic CO 2 reduction Covalent organic polymer Dry-reforming of methane Electron donor and acceptor

Targeting the chromatin structural changes of antitumor immunity

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Pharmaceutical Analysis 2024年第4期14卷 460-482页

作者： Nian-nian li Deng-xing Lun Ningning Gong Gang Meng xin-ying Du He Wang Xiangxiang Bao xin-yang li Ji-wu Song Kewei hu Lala li Si-ying li Wenbo liu Wanping Zhu Yunlong Zhang Jikai li Ting Yao Leming Mou Xiaoqing Han Furong Hao Yongcheng hu lin liu Hongguang Zhu Yuyun Wu Bin liu Weifang People's Hospital WeifangShandong261000China School of life Sciences Nankai UniversityTianjin300071China Weifang Traditional Chinese Medicine Hospital WeifangShandong261000China Shaanxi Key Laboratory of Sericulture Ankang UniversityAnkangShaanxi725000China Guizhou Education University Guiyang550018China Guizhou Normal University Guiyang550025China School of Medical Imaging Weifang Medical UniversityWeifangShandong261053China Department of Bone and Soft Tissue Oncology Tianjin HospitalTianjin300299China xinqiao Hospital of Army Military Medical University Chongqing400038China Teda Institute of Biological Sciences&Biotechnology Nankai UniversityTianjin300457China

Epigenomic imbalance drives abnormal transcriptional processes,promoting the onset and progression of *** defective gene regulation generally affects carcinogenesis and tumor suppression networks,tumor immunogenicity and immune cells involved in antitumor responses may also be affected by epigenomic changes,which may have significant implications for the development and application of epigenetic therapy,cancer immunotherapy,and their ***,we focus on the impact of epigenetic regulation on tumor immune cell function and the role of key abnormal epigenetic processes,DNA methylation,histone post-translational modification,and chromatin structure in tumor immunogenicity,and introduce these epigenetic research *** emphasize the value of small-molecule inhibitors of epigenetic modulators in enhancing antitumor immune responses and discuss the challenges of developing treatment plans that combine epigenetic therapy and immuno-therapy through the complex interaction between cancer epigenetics and cancer immunology.

关键词： Antitumor immunity Chromatin structural Cancer epigenetics DNA methylation Histone modification Chemotherapy

A Golden2-like transcription factor, BnGLK1a, improves chloroplast development, photosynthesis, and seed weight in rapeseed

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2024年第5期23卷 1481-1493页

作者： Qianwei zhang Yuanyi Mao Zikun Zhao xin hu Ran hu Nengwen Yin Xue Sun Fujun Sun Si Chen Yuxiang jiang liezhao liu Kun Lu Jiana li Yu Pan Integrative Science Center of Germplasm Creation in Western China(Chongqing)Science City Southwest UniversityChongqing 400715China Academy of Agricultural Sciences Southwest UniversityChongqing 400715China Engineering Research Center of South Upland Agriculture Ministry of EducationChongqing 400715China Key Laboratory of Horticulture Science for Southern Mountainous Regions Ministry of Education/College of Horticulture and Landscape ArchitectureSouthwest UniversityChongqing 400715China

Enhancing photosynthetic efficiency is a major goal for improving crop yields under agricultural field conditions and is associated with chloroplast biosynthesis and *** this study,we demonstrate that Golden2-like 1a(BnGLK1a)plays an important role in regulating chloroplast development and photosynthetic *** BnGLK1a resulted in significant increases in chlorophyll content,the number of thylakoid membrane layers and photosynthetic efficiency in Brassica napus,while knocking down BnGLK1a transcript levels through RNA interference(RNAi)had the opposite effects.A yeast two-hybrid screen revealed that BnGLK1a interacts with the abscisic acid receptor PYRABACTIN RESISTANCE 1-liKE 1-2(BnPYL1-2)and CONSTITUTIVE PHOTOMORPHOGENIC 9 SIGNALOSOME 5A subunit(BnCSN5A),which play essential roles in regulating chloroplast development and *** with this,BnGLK1a-RNAi lines of *** display hypersensitivity to the abscisic acid(ABA)***,overexpression of BnGLK1a resulted in a 10%increase in thousand-seed weight,whereas seeds from BnGLK1a-RNAi lines were 16%lighter than wild *** propose that BnGLK1a could be a potential target in breeding for improving rapeseed *** results not only provide insights into the mechanisms of BnGLK1a function,but also offer a potential approach for improving the productivity of Brassica species.

关键词： Brassica napus BnGLK1a chloroplast development photosynthetic efficiency yield

A sustainable process to 100%bio-based nylons integrated chemical and biological conversion of lignocellulose

在线全文

学校读者我要写书评

暂无评论

Green Energy & Environment 2024年第2期9卷 390-402页

作者： Ruijia hu Ming li Tao Shen xin Wang Zhuohua Sun xinning Bao Kequan Chen Kai Guo Lei Ji Hanjie Ying Pingkai Ouyang Chenjie Zhu College of Biotechnology and Pharmaceutical Engineering Nanjing Tech UniversityNanjingChina National Engineering Research Center for Biotechnology Nanjing Tech UniversityNanjingChina Beijing Key Laboratory of lignocellulosic Chemistry Beijing Forestry UniversityBeijingChina

Considerable progress has been made in recent years to the development of sustainable polymers from bio-based *** this study,100%bio-based nylons were prepared via an integrated chemical and biological process from *** novel nylons were obtained by the melt polymerization of 3-propyladipic acid derived from lignin and 1,5-pentenediamine/1,4-butanediamine derived from carbohydrate *** to the concept is a three-step noble metal free catalytic chemical funnelling sequence(Raney Ni mediated reductive catalytic fractionation-reductive funnelling-oxidative funnelling),which allowed for obtaining a single component 3-propyladipic acid from lignin with high *** structural and thermodynamic properties of the obtained nylons have been systematically investigated,and thus obtained transparent bio-based nylons exhibited higher Mw(>32,000)and excellent thermal stability(Td5%>265℃).Considering their moderate Tg and good melt strength,these transparent bio-based nylons could serve as promising functional additives or temperature-responsive materials.

关键词： lignocellulose lignin Reductive catalytic fractionation Bio-based nylon

Solid solution strategy modulated defects engineering of(Cr_(1-x)V_(x))_(2)AlC MAX phase toward superior electromagnetic wave absorption

在线全文

学校读者我要写书评

暂无评论

Rare Metals 2024年第7期43卷 3205-3219页

作者： Ji-lin Gou Yu-Kai Chang Shu liu Peng-hui li Ping-Hao Cui Qian-Ku hu li-Bo Wang xin Zhang Jun-Kai Wang Qi-Xun Xia Ai-Guo Zhou School of Materials Science and Engineering Henan Polytechnic UniversityJiaozuo 454003China Key Laboratory for Microstructural Material Physics of Hebei Province School of ScienceYanshan UniversityQinhuangdao 066004China State Key Laboratory of Metastable Materials Science and Technology Yanshan UniversityQinhuangdao 066004China

Defects engineering is an effective strategy for manipulating electromagnetic parameters and enhancing electromagnetic wave(EMW)absorption ***,the relationship between them is not clear,especially in solid solution *** this work,a series of(Cr_(1-x)V_(x))_(2)AlC MAX phase solid solutions with layered structure were prepared via tuning the ratio of Cr and V to explore their EMW absorption *** experimental results indicated that the doping of V atoms at the M-site could effectively regulate its impedance matching and EMW absorption properties by introducing appropriate numbers of defects in the crystal,such as twin boundaries,dislocations and lattice *** them,if Cr:V=3:1,Cr_(1.5)V_(0.5)AlC,as radar absorption materials,could reach a strong reflection loss of-51.8 dB at the frequency of 12.8 GHz under an ultra-thin thickness of 1.3 *** reflection loss value could attain-10 dB in a wide frequency range of 2.7-18 GHz and thickness range of 1-5 *** addition,after high temperature and acid-alkali immersion treatment,this sample still had good EMW absorption capability,and the effective absorption bandwidth was enhanced from 2.3 to 2.6 GHz after concentrated acid immersion or 3.1 GHz after concentrated alkali *** work has great reference significance for the research and development of high-performance MAX-based EMW absorption materials in harsh environments.

关键词： MAX phases Solid solution Defects engineering Electromagnetic wave absorption Harsh environments

Evolution and conservation genetics of pangolins

在线全文

学校读者我要写书评

暂无评论

Integrative Zoology 2024年第3期19卷 426-441页

作者： Tongtong GU Jingyang hu li YU State Key Laboratory for Conservation and Utilization of Bio-Resource in Yunnan School of Life SciencesYunnan UniversityKunmingChina

Pangolins(Pholidota,Manidae)are classified as an evolutionarily distinct and globally endangered mammal due to their unique morphology(nail-like scales and a myrmecophagous diet)and being the victim of heavy poaching and worldwide *** such,pangolins serve as a textbook example for studying the special phenotypic evolutionary adaptations and conservation genetics of an endangered *** years have demonstrated significant advancements in the fields of molecular genetics and genomics,which have translated to a series of important research achievements and breakthroughs concerning the evolution and conservation genetics of *** review comprehensively presents the hitherto advances in phylogeny,adaptive evolution,conservation genetics,and conservation genomics that are related to pangolins,which will provide an ample understanding of their diversity,molecular adaptation mechanisms,and evolutionary *** addition,we highlight the priority of investigating species/population diversity among pangolins and suggest several avenues of research that are highly relevant for future pangolin conservation.

关键词： adaptive evolution conservation genetics conservation genomics pangolins phylogeny

Formation of Superthin Galaxies in IllustrisTNG

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2024年第7期24卷 235-248页

作者： Jianhong hu Dandan Xu Cheng li Department of Astronomy Tsinghua UniversityBeijing 100084China

Superthin galaxies are observed to have stellar disks with extremely small minor-to-major axis *** this work,we investigate the formation of superthin galaxies in the TNG100 *** trace the merger history and investigate the evolution of galaxy properties of a selected sample of superthin galaxies and a control sample of galaxies that share the same joint probability distribution in the stellar-mass and color *** making comparisons between the two galaxy samples,we find that present-day superthin galaxies had similar morphologies as the control sample counterparts at higher redshifts,but have developed extended flat“superthin”morphologies since z~*** this latter evolution stage,superthin galaxies undergo an overwhelmingly higher frequency of prograde mergers(with orbit-spin angleθ_(orb)≤40°).Accordingly the spins of their dark matter halos have grown significantly and become noticeably higher than those of their normal disk *** further results in the buildup of their stellar disks at larger distances much beyond the regimes of normal disk *** also discuss the formation scenario of those superthin galaxies that live in larger dark matter halos as satellite galaxies therein.

关键词： Galaxies formation-Galaxies evolution-Galaxies interactions-Galaxies star formation

Enhancing Relational Triple Extraction in Specific Domains:Semantic Enhancement and Synergy of Large Language Models and Small Pre-Trained Language Models

在线全文

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2024年第5期79卷 2481-2503页

作者： Jiakai li Jianpeng hu Geng Zhang School of Electronic and Electrical Engineering Shanghai University of Engineering ScienceShanghai201620China

In the process of constructing domain-specific knowledge graphs,the task of relational triple extraction plays a critical role in transforming unstructured text into structured *** relational triple extraction models facemultiple challenges when processing domain-specific data,including insufficient utilization of semantic interaction information between entities and relations,difficulties in handling challenging samples,and the scarcity of domain-specific *** address these issues,our study introduces three innovative components:Relation semantic enhancement,data augmentation,and a voting strategy,all designed to significantly improve the model’s performance in tackling domain-specific relational triple extraction *** first propose an innovative attention interaction *** method significantly enhances the semantic interaction capabilities between entities and relations by integrating semantic information fromrelation ***,we propose a voting strategy that effectively combines the strengths of large languagemodels(LLMs)and fine-tuned small pre-trained language models(SLMs)to reevaluate challenging samples,thereby improving the model’s adaptability in specific ***,we explore the use of LLMs for data augmentation,aiming to generate domain-specific datasets to alleviate the scarcity of domain *** conducted on three domain-specific datasets demonstrate that our model outperforms existing comparative models in several aspects,with F1 scores exceeding the State of the Art models by 2%,1.6%,and 0.6%,respectively,validating the effectiveness and generalizability of our approach.

关键词： Relational triple extraction semantic interaction large language models data augmentation specific domains

Classifying hepatitis B therapies with insights from covalently closed circular DNA dynamics

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Virologica Sinica 2024年第1期39卷 9-23页

作者： Jie-li hu Ai-Long huang Key Laboratory of Molecular Biology on Infectious Diseases Ministry of EducationChongqing Medical UniversityChongqing400016China

The achievement of a functional cure for chronic hepatitis B(CHB)remains limited to a minority of patients treated with currently approved *** primary objective in developing new anti-HBV drugs is to enhance the functional cure rates for CHB.A critical prerequisite for the functional cure of CHB is a substantial reduction,or even eradication of covalently closed circular DNA(cccDNA).Within this context,the changes in cccDNA levels during treatment become as a pivotal *** have previously analyzed the factors influencing cccDNA dynamics and introduced a preliminary classification of hepatitis B treatment strategies based on these *** this review,we employ a systems thinking perspective to elucidate the fundamental aspects of the HBV replication cycle and to rationalize the classification of treatment strategies according to their impact on the dynamic equilibrium of *** upon this foundation,we categorize current anti-HBV strategies into two distinct groups and advocate for their combined use to significantly reduce cccDNA levels within a well-defined timeframe.

关键词： Hepatitis B cccDNA Functional cure Dynamics Treatment Strategy