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Tungsten 2025年第1期7卷 32-49页

作者： li-rong xiao Chen Chen Shuo Wang Zi-Yin Dai Hideo Kimura Cui Ni Chuan-Xin Hou Xue-Qin Sun Si-Jie Guo Wei Du Xiu-Bo Xie School of Environmental and Material Engineering Yantai University Bosch HUAYU Steering Systems (Yantai) Co. Ltd.Ytp/MFE University of Tennessee Knoxville Shandong Key Laboratory of Eco-Environmental Science for the Yellow River Delta Shandong University of Aeronautics

MgH2is considered as a promising hydrogen storage material for its high hydrogen storage capacity,low cost and abundant resource ***,the low kinetics and high enthalpy formation of MgH2limit its wide *** the perspective of adding catalysts to enhance the hydrogen storage properties of Mg-MgH2,this article elaborated the main catalysts based on Ti and Nb transition elements,including single oxide catalysts,binary oxides catalysts（combined with Ni,Na,Sr,V,etc.）,multiple catalysts bound to carbon,and composite catalysts with Ti and Nb elements combined with MXene ***,the main pathways of various catalysts to reduce the reaction activity and broaden the hydrogen desorption channel were also *** Ti-based catalysts can enhance the reactive sites of the matrix by forming multivalent states,while Nb-based catalysts broaden the hydrogen reaction channels by forming tiny *** improving the size structure and enhancing the grain size stability,combined with carbon materials should be the future considerations.

关键词： Catalysts Mg-based hydrogen storage alloys Solid hydrogen storage Transition metal elements

The bioinformatics and metabolomics research on anti-hypoxic molecular mechanisms of Salidroside via regulating the PTEN mediated PI3K/Akt/NF-κB signaling pathway

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Chinese Journal of Natural Medicines 2021年第6期19卷 442-453页

作者： WU Yi MA Yi li Jing ZHOU Xue-lin li Lei XU Ping-Xiang li xiao-rong XUE Ming Department of Pharmacology Beijing Laboratory for Biomedical Detection Technology and InstrumentSchool of Basic Medical SciencesCapital Medical UniversityBeijing 100069China Beijing Engineering Research Center for Nerve System Drugs Beijing 100053China Central Laboratory Capital Medical UniversityBeijing 100069China

Salidroside(SAL),a major bioactive compound of Rhodiola crenulata,has significant anti-hypoxia effect,however,its underlying molecular mechanism has not been *** order to explore the protective mechanism of SAL,the lactate dehydrogenase(LDH),reactive oxygen species(ROS),superoxide dismutase(SOD)and hypoxia-induced factor 1α(HIF-1α)were measured to establish the PC12 cell hypoxic *** staining and cell viability analyses were performed to evaluate the protective effects of *** metabolomics and bioinformatics methods were used to explore the protective effects of salidroside under hypoxia *** metabolite-protein interaction networks were further established and the protein expression level was examined by Western *** results showed that 59 endogenous metabolites changed and the expression of the hub proteins of CK2,p-PTEN/PTEN,PI3K,p-Akt/Akt,NF-κB p65 and Bcl-2 were increased,suggesting that SAL could increase the expression of CK2,which induced the phosphorylation and inactivation of PTEN,reduced the inhibitory effect on PI3K signaling pathways and activated the PI3K/Akt/NF-κB survival signaling *** study provided an important insight to reveal the protective molecular mechanism of SAL as a novel drug candidate.

关键词： Salidroside Hypoxia PC 12 Metabolomics PTEN PI3K/Akt/NF-κB

Direct Synthesis of Nitriles from Aldehydes in Ionic liquids

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Chemical Research in Chinese Universities 2011年第4期27卷 712-714页

作者： ZHANG Jun-li CHEN xiao-rong YU Yan-peng XU Kun-ling HUANG Jun State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemistry and Chemical Engineering Nanjing University of Technology Nanjing 210009 P. R. China

1 Introduction Ionic liquids（ILs） are environmentally acceptable solvents because they have low vapor pressure, high thermal stability and chemical stability, excellent solvent for organic and inorganic compounds. Therefore, they can be used as green solvents for a number of chemical processes, such as separa- tions and reactions. ILs are also used as catalysts in chemical reactions to accelerate reaction rate and improve selectivity.

关键词： Nitrile Aldehyde Hydroxylamine hydrochloride Ionic liquid

A Summary of the Research on the Rural Sages Culture

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Journal of literature and Art Studies 2018年第11期8卷 1581-1587页

作者： li xiao-rong Yancheng Institute of Technology JiangsuChina

As a cultural phenomenon rooted in the traditional rural society China,rural sages culture has played an important role in the inheritance of civilization and social *** new period,rural sages culture helps to cultivate rural civilization and promote the development of rural economy and rural social *** the process of innovation and development of rural sages culture,across the rural have all made great achievements,which initiatives in Zhejiang and Guangdong province is *** this basis,the mechanism to play rural sages’role mainly includes:researching rural sages culture,strengthening the construction of the scholarly society,attracting rural sages regression and remodeling of the rural elite etc.

关键词： summary research rural sage culture

Mouse strain differences in selective serotonin reuptake inhibitors sensitivity correlates with serotonin transporter binding and function

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中国药理学与毒理学杂志 2018年第9期32卷 710-711页

作者： JIN Zeng-liang CHEN xiao-fei li xiao-rong XIONG Jie ZHENG Yuan-yuan GAO Na-na li Yun-feng Beijing Key laboratory of Neuropsychopharmacology Beijing Institute of Pharmacology and Toxicology Department of Pharmacology School of Basic Medical SciencesCapital Medical University

OBJECTIVE Selective serotonin reuptake inhibitors(SSRIs) bind 5-HT transporters,leading to the accumulation of 5-HT and amelioration of *** different mouse strain showed different sensitivity to SSRIs in mouse models of depression,the reason for these strain differences remains ***,therefore,in the present study,we examined immobility time and locomotor activity in two mouse strains,namely,C57BL/6 J and DBA/2 J mice,and the effects of the SSRIs ***,we analyzed 5-HT transporter binding and reuptake inhibition in both strains to explore their relationship with the immobility and locomotor activity effects of the three SSRIs in these two mouse *** Strain differences in SSRI effects in the tail suspension test(TST) and forced swimming test(FST).To initiate our studies,we sought to confirm that SERT strain variation did not alter SERT protein expression,5-HT recognition,or uptake activity when expressed in C57BL/6 J and DBA/2 J *** binding assays were conducted to determine the affinity of the SSRIs for the 5-HT transporters in the two mouse *** SSRI citalopram dose-dependently reduced immobility time in both the FST and TST in DBA/2 J but not C57BL/6 J mouse strains,whereas fluoxetine showed opposite *** reduced immobility time similarly in both *** affinity of citalopram for the 5-HT transporter in DBA/2 J mice was 700-fold higher than that for in C57BL/6 J mice,whereas the affinity of fluoxetine in C57BL/6 J mice was 100-fold higher than that in the DBA/2 J ***,High citalopram concentrations were required to [3 H]5-HT uptake in C57BL/6 J but not DBA/2 J mouse cortical synaptosomes,whereas fluoxetine also showed opposite *** Immobility duration depends on 5-HT transporter binding levels,leading to apparent strain differences in immobility time in FST and ***,differences in 5-HT transporter binding may cause variations in SSRI

关键词： antidepressants mouse strains selective serotonin reuptake inhibitors

High Acoustic Nonlinearity of a liquid Containing Microbubbles

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Chinese Physics Letters 1999年第10期16卷 737-739页

作者： liU Jie-hui ZHANG Dong GONG Xiu-fen SHAO li-zheng li xiao-rong CHEN Xi ZHANG Qin-lan State Key Laboratory of Modern Acoustics Institute of AcousticsNanjing UniversityNanjing 210093 Wuxi No.1 People’s Hospital Wuxi 214002

The acoustic nonlinearity parameter B/A of a liquid containing microbubbles,sonicated dextrose albumin,has been measured by using second harmonic insert-substitution *** show that the value of nonlinearity parameter B/A for a bubbly liquid is significant and it obviously increases with increase of bubble number *** high nonlinearity of the bubbly liquid is mainly dependent on the microbubble nonlinear oscillation.

关键词： oscillation. density. method.

Analysis of principle deviation of subpixel Zernike moments operator

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Optoelectronics Letters 2007年第5期3卷 376-380页

作者： QU Ying-dong li rong-de YUAN xiao-guang HUANG Hong-jun li Chen-xi School of Material and Engineering Shenyang University of Technology Shenyang 110023 China

In original Zernike moments subpixel edge operator, ideal step edge model is chosen for calculating four parameters of a pixel point, and therefore principle deviation is caused by edge model. In order to discuss the effect of principle deviation on edge location, sampled edge model is chosen for calculating edge parameters, principle deviation of edge translation l is derived based on Zernike moments edge detection theory, and modified formula of l is given for Zernike moments operator with masks of 5×5 size. Both theory analysis and testing result demonstrate that principle deviation is zero when edge translation l is limited in central pixel of a sampled window. In another case, the modification of l should be considered, which results in edge location accuracy of non-subpixel level for this subpixel edge operator.

关键词：图象处理偏差边缘算子边界模型

Analysis of the key networks,metabolic pathways,and regulation substances of hypoxia based on the omics and zebrafish model

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中国药理学与毒理学杂志 2017年第10期31卷 1023-1024页

作者： Yi MA Bin-bin XIA Jing-yi li Zheng-chao XIA Ping-xiang XU li xiao-rong Ming XUE Department of Pharmacology School of Basic Medical SciencesCapital Medical University

OBJECTIVE Hypoxia is associated with many complicated pathophysiological and biochemical processes that integrated and regulated via the key gene,protein and endogenous metabolite *** to date,the exact molecular mechanism of hypoxia still remains *** this work,we further explore the molecular mechanism of hypoxia and adaption to attenuate the damage in zebrafish model that have potential to resist hypoxic *** The hypoxic zebrafish model was established in different concentration of oxygen with 3%,5%,10%,21%in *** brain tissue was separated and the RNA-seq was used to identify the differentially expressed *** related endogenous metabolites profiles were obtained by LC-HDMS,and the multivariate statistics was applied to discover the important metabolites candidates in hypoxic *** candidates were searched in HMDB,KEGG and lipid Maps *** The zebrafish hypoxic model was successfully constructed via the different concentration of oxygen,temperature and hypoxic *** activities of the related hypoxic metabolic enzymes and factors including HIF-1a,actate dehydrogenase(LDH)and citrate synthase(CS)were *** differences(P2)in the expression of 422 genes were observed between the normal and 3% hypoxic *** them,201 genes increased depended on the lower concentration of oxygen.53 metabolites were identified that had significant difference between the hypoxia and control groups(P1.5 and VIP>1.5).The ten key metabolites were increased gradually while six compounds were *** endogenous hypoxic metabolites of phenylalanine,D-glucosamine-6P and several important lipids with the relevant hub genes had similar change in hypoxic *** addition,the metabolic pathways of phenylalanine,glutamine and glycolipid were influenced in both the levels of genes and *** The up-regulation of phenylalanine,D-glucosamine-6P and lipid may hav

关键词： hypoxia adaptation metabolic pathway omics zebrafish model

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陆游诗歌“化身梅”范式的建立及后世影响

中山大学学报（社会科学版） 2023年第6期63卷 37-46页

作者：李小荣福建师范大学闽台区域研究中心福州350007

陆游咏梅创作前后持续50余年,其取材方式、思想表达常与佛教相联系,这既是受到家族佛教信仰、诗学师承两种传统的影响所致,更和陆游一生好结交禅僧的社会生活经历息息相关。特别是淳熙五年(1178)秋松源崇岳禅师对他的印可,奠定了他此后... 详细信息

陆游咏梅创作前后持续50余年,其取材方式、思想表达常与佛教相联系,这既是受到家族佛教信仰、诗学师承两种传统的影响所致,更和陆游一生好结交禅僧的社会生活经历息息相关。特别是淳熙五年(1178)秋松源崇岳禅师对他的印可,奠定了他此后特殊“寻梅眼”的观物审美方式。再经24年的禅修实践和创作积淀,至嘉泰二年(1202)春,终于以超越前贤的创新意识,融汇“三时论门”“六根互用”和松源禅系的“华严意蕴”等多种佛教思想以及佛教文学的因子,创建了在明末清初以降具有深远影响的咏梅范式——“化身梅”。后世咏梅接受该范式影响的文本表现方式,主要有正引、反引、诗意图和组合型等四大类。

关键词：陆游诗歌化身梅范式后世影响

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简论汉译佛典之“譬喻”文体

福建师范大学学报（哲学社会科学版） 2009年第5期 65-73页

作者：李小荣福建师范大学文学院福建福州350108

在汉译佛典中,"譬喻"虽有多种含义,但作为一种重要而独立的叙事文体,其性质则相当于中土固有的寓言,且具有独特的文体表现:如从组织结构言,可分成原始例证型、独立完整型和变化复合型;从故事与寓意之间的对应关系看,则有一一对应、一多... 详细信息

在汉译佛典中,"譬喻"虽有多种含义,但作为一种重要而独立的叙事文体,其性质则相当于中土固有的寓言,且具有独特的文体表现:如从组织结构言,可分成原始例证型、独立完整型和变化复合型;从故事与寓意之间的对应关系看,则有一一对应、一多对应、多一对应、双重并列及多重对应等关系;从寓象与寓意关系的生成机制看,则主要表现为相似联想、对比联想、接近联想和关系联想。

关键词：汉译佛典譬喻文体表现