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Surgical complexity and prognostic outcome of small volume renal cell carcinoma with high-level venous tumor thrombus and large volume renal cell carcinoma with low-level thrombus

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Chinese Medical Journal 2019年第15期132卷 1780-1787页

作者： Zhuo liu Xun Zhao Hong-Xian Zhang li-wei li Shi-Ying Tang Guo-liang Wang Shu-Dong Zhang Shu-Min Wang Lu-lin Ma Xiao-Jun Tian Department of Urology Peking University Third Hospital Beijing 100191 China Department of Ultrasound Peking University Third Hospital Beijing 100191 China

Background:Radical nephrectomy with thrombectomy is one of the most difficult and complicated urological *** the roles of renal tumor volume and thrombus level in surgical complexity and prognostic outcome are not *** study aimed to evaluate the surgical complexity and prognostic outcome between the volume of renal cell carcinoma (RCC) and the level of venous tumor ***:The clinical data of 67 RCC cases with renal vein or inferior vena cava (IVC) tumor thrombus from January 2015 to May 2018 were retrospectively *** these 67 cases,21 (31.3%) were small tumors with high-level thrombus (tumor ≤7 cm in diameter and thrombus Neves Level Ⅱ-Ⅳ),while 46 (68.7%) were large tumors with low-level thrombus group (tumor >7 cm in diameter and thrombus Level 0-Ⅰ).Clinical features,operation details,and pathology data were *** and multivariable logistic regression analyses were applied to evaluate the risk factors for small tumor with high-level ***:Patients with small tumors and high-level thrombus were more likely to have longer operative time (421.9 ± 135.1 min vs.282.2 ± 101.9 min,t=4.685,P lications (52.4% vs.19.6%,x2 =7.415,P =0.010) than patients with large tumors and low-level *** multivariate analysis,decreased hemoglobin (Hb)(odds ratio [OR]:0.956,95 % confidence interval [CI]:0.926-0.986,P =0.005) and non-sarcomatoid differentiation (OR:0.050,95% CI:0.004-0.664,P =0.023) were more likely to form small tumors with high-level tumor t

关键词： Inferior vena cava Tumor thrombus Renal cell carcinoma Cancer-specific survival Prognosis Neves classification

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Metal nanoparticles decorated CoFe-(oxy)hydroxysulfides nanosheets fabricated by a general strategy for electrocatalytic water splitting

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Journal of Energy Chemistry 2025年第1期100卷 26-38页

作者： Xiaodong Yang Haochen Shen Xiaoming Xiao Zhichao li Qi Zhou wei Yang Bin Jiang Yongli Sun Luhong Zhang Zhenhua Yan School of Chemical Engineering and Technology Tianjin University Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education) Nankai University

This study presents a novel method to fabricate metal-decorated,sulfur-doped layered double hydroxides （M/SLDH） through spontaneous redox and sulfurization *** developed Ag/SLDH and Pt/SLDH catalysts with abundant heterogeneous interfaces and hierarchical nanostructures demonstrated outstanding oxygen evolution reaction （OER） and hydrogen evolution reaction （HER） performance,achieving low overpotentials of 212 and 35 mV at 10 mA cm-2in 1 M KOH,*** both anode and cathode in water splitting,they required only 1.47 V to reach 10 mA cm-2and exhibited high structural robustness,maintaining stability at 1000 mA cm-2for 300 ***-situ Raman analysis revealed that the synergistic effects of metal nanoparticles and S doping significantly promote the transformation into the S-Co1-xFexOOH layer,which serves as the active phase for water ***,ultraviolet photoelectron spectroscopy （UPS） and density functional theory （DFT） analyses indicated that incorporating metal nanoparticles and S doping increase electron density near the Fermi level and reduce reaction energy barriers,thus enhancing intrinsic OER and HER *** study provides a scalable strategy for synthesizing high-performance electrocatalysts for water splitting,with promising potential for broader applications.

关键词： LDH Spontaneous reaction Metal nanoparticles Water splitting

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凹凸棒脱硫剂选择性脱除模拟油中苯并噻吩的研究

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矿物岩石 2016年第4期36卷 10-15页

作者：焦林宏李薇李超超韩维亮赵立祥马娅兰州石化职业技术学院石油化学工程系甘肃兰州730060 中科院兰州化学物理研究所精细石油化工中间体国家工程研究中心甘肃兰州730000

采用浸渍法制备盱眙凹凸棒黏土脱硫剂,负载硝酸铁和硝酸银活性组分。通过正交试验考察了脱硫剂制备和吸附脱除模拟油中苯并噻吩的最佳工艺条件。结果表明:硝酸铁质量分数8%,硝酸银质量分数1%,400℃下焙烧3h制备脱硫剂,在常温常压条件下... 详细信息

采用浸渍法制备盱眙凹凸棒黏土脱硫剂,负载硝酸铁和硝酸银活性组分。通过正交试验考察了脱硫剂制备和吸附脱除模拟油中苯并噻吩的最佳工艺条件。结果表明:硝酸铁质量分数8%,硝酸银质量分数1%,400℃下焙烧3h制备脱硫剂,在常温常压条件下,模拟油中的硫质量分数从400×10^(-6)降至平均106×10^(-6),脱硫率达到73.5%。Fe和Ag离子通过π络合作用吸附脱除苯并噻吩,但Ag离子吸附苯并噻吩能力强于Fe离子。

关键词：凹凸棒黏土脱硫苯并噻吩

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MULTI-SENSOR TRACING PRINCIPLE FOR CRANKSHAFT ROUNDNESS MEASUREMENT DURING NONCIRCULAR GRINDING PROCESS

MULTI-SENSOR TRACING PRINCIPLE FOR CRANKSHAFT ROUNDNESS MEAS...

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2006年中国机械工程学会年会暨中国工程院机械与运载工程学部首届年会

作者： TIAN Yingzhong, li Ming, li wei, WU Ganghua, FANG Minglun CIMS & Robot Center of Shanghai University, 200072 Shanghai, China

During noncircular grinding process (NGP), the crankshaft eccentrically rotates around the crankpin center, instead of itself center. This paper presents an expatiation on the three-sensor tracing pri

关键词： Noncircular grinding process three-sensor tracing principle two-sensor tracing principle roundness error crankshaft.

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油气成藏保存条件的综合研究

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石油学报 1997年第2期18卷 41-48页

作者：李明诚李伟蔡峰孙大明中国地质大学

从盖层、断层、抬升剥蚀、岩浆活动、生储盖组合的时空跨距和储、盖层岩石物性和源岩质量等方面进行了油气藏保存条件定性的研究，并从油气的散失量和聚集量的模拟，对保存条件进行了定量的研究。通过４个油气藏（田）保存条件的研究和... 详细信息

从盖层、断层、抬升剥蚀、岩浆活动、生储盖组合的时空跨距和储、盖层岩石物性和源岩质量等方面进行了油气藏保存条件定性的研究，并从油气的散失量和聚集量的模拟，对保存条件进行了定量的研究。通过４个油气藏（田）保存条件的研究和对比，提出了保存条件定性评价的七个地质标准和两个定量评价参数，为油气藏保存条件的综合研究提供了较科学的依据。

关键词：油气藏保存条件模拟二次运移

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STUDY ON MOVEMENT MODEL OF TRACING MEASUREMENT EQUIPMENT DURING CRANKSHAFT NONCIRCULAR GRINDING PROCESS

STUDY ON MOVEMENT MODEL OF TRACING MEASUREMENT EQUIPMENT DUR...

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2006年中国机械工程学会年会暨中国工程院机械与运载工程学部首届年会

作者： li wei, li Ming, ZHAO Xiaoyin, TIAN Yingzhong, PENG Qiusheng CIMS & Robot Center of Shanghai University, Shanghai 200072, China

The characteristic of noncircular grinding process causesthe crankshaft online measurement to be extremely *** paper proposes one new online active trackingmeasuring technique which checks

关键词： Noncircular grinding process in-situmeasurement velocity model roundness.

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磁性槽楔对永磁电机转子损耗及温度场影响

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电机与控制学报 2016年第1期20卷 60-66页

作者：黄东洙李伟力王耀玉曹钊滨哈尔滨理工大学电气与电子工程学院黑龙江哈尔滨150080 北京交通大学电气工程学院北京100044

针对实心转子高压永磁电机定子铁心开槽会导致气隙磁导不均匀,气隙中谐波磁场引起电机转子温度升高,影响永磁体的电磁性能的问题,以一台315 k W,6 k V实心转子高压永磁电机为例,建立了样机的二维电磁场时步有限元模型及三维全域流体与... 详细信息

针对实心转子高压永磁电机定子铁心开槽会导致气隙磁导不均匀,气隙中谐波磁场引起电机转子温度升高,影响永磁体的电磁性能的问题,以一台315 k W,6 k V实心转子高压永磁电机为例,建立了样机的二维电磁场时步有限元模型及三维全域流体与固体耦合传热数学模型,给出了求解域及边界条件,通过求解计算模型,将计算数据与实验数据进行了对比,验证了所建模型的正确性。在此基础上研究了槽楔相对磁导率分别为3、5、7、9时对转子表面涡流损耗的影响,分析了磁性槽楔相对磁导率为不同值时电机转子及定子各部分的温度分布,计算结果表明定子槽楔相对磁导率数值的增加,电机的起动转矩降低,转子铁心涡流损耗逐渐减小,电机定子各部分温度先减小后趋于稳定。

关键词：永磁电机磁性槽楔实心转子涡流损耗温度场

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Simultaneous Determination of Silybin A and Silybin B in Rat Plasma and Pharmacokinetic Study

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Chinese Herbal Medicines 2011年第4期3卷 304-309页

作者： CHU Yang,li wei,li Zhi-wen,li Xin-xin,MA Xiao-hui,ZHOU Shui-ping,ZHU Yong-hong Department of Pharmacology,Tianjin Tasly Institute,Tianjin 300410,China Department of Pharmacology Tianjin Tasly Institute Tianjin 300410 China

Objective To investigate the bioavailability and pharmacokinetics of silybin A and silybin B in rats,respectively. Methods Following iv and ig administration of silybin to 20 Wistar rats,the plasma samples were collected at different time points up to 12 *** pretreatment was involved in one-step protein precipitation with acetonitrile. Silybin A and silybin B were simultaneously determined by LC-MS/*** After ig dosing silybin 28,56,and 112 mg/kg to rats,the t1/2βvalues were 5.48,5.08,and 5.73 h for silybin A,and 4.56,4.12,and 5.53 h for silybin B; The Cmax were 674.3,1349.4,and 2042.5 ng/mL for silybin A,and 671.0,1365.4,and 2066.2 ng/mL for silybin B; The Tmax were 0.20,0.23,and 0.20 h for silybin A,and 0.20,0.23,and 0.20 h for silybin B;The AUC were 454.4, 845.9,and 1219.5 h·ng/mL for silybin A,and 432.0,817.1,and 1153.6 h·ng/mL for silybin *** absolute bioavailabilities of silybin A and silybin B were 2.86%and 1.93%,*** Silybin A and silybin B have very low bioavailability after ig administration,and there is no significant difference in the pharmacokinetic parameters between silybin A and silybin B,which indicates that the two diastereoisomers have similar pharmacokinetic behavior in rats.

关键词： bioavailability LC-MS/MS pharmacokinetics silybin A silybin B

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Hybrid Electrochemical "Adsorption-Desorption" and Colorimetric Methods for Selectively In Situ Determination of Metal Ions

Hybrid Electrochemical "Adsorption-Desorption" and Colorimet...

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第六届全国环境化学大会暨环境科学仪器与分析仪器展览会

作者： Meng li,Da-wei li,Yuan-Ting li and Yi-Tao Long~* (Shanghai Key Laboratory of Functional Materials Chemistry,East China University of Science and Technology,Shanghai 200237)

Heavy metal ion pollutant constitutes the environmental problems that deserve public attention in *** common analytical techniques for detection of heavy metal ions are AAS;ICP-AES and ICP-MS. Although these techniques are generally used as standard laboratory methods,the development of inexpensive and simple methods for the in situ determination of heavy metal ion concentrations is still ***,a novel and facile hybrid analytical method coupling electrochemical "adsorption-desorption" and colorimetric analyses was developed to detect heavy metal ions in turbid water *** demonstrated the applicability of this method by detecting Cd,Pb and

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Differential distribution of PINK1 and Parkin in the primate brain implies distinct roles

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Neural Regeneration Research 2025年第4期20卷 1124-1134页

作者： Yanting liu wei Huang Jiayi Wen Xin Xiong Ting Xu Qi Wang Xiusheng Chen Xianxian Zhao Shihua li Xiaojiang li weili Yang Guangdong Key Laboratory of Non-human Primate Research Key Laboratory of CNS Regeneration(Ministry of Education)Guangdong-Hongkong-Macao CNS Regeneration Institute of Jinan UniversityJinan UniversityGuangzhouGuangdong ProvinceChina

The vast majority of in vitro studies have demonstrated that PINK1 phosphorylates Parkin to work together in mitophagy to protect against neuronal ***,it remains largely unclear how PINK1 and Parkin are expressed in mammalian *** has been difficult to address because of the intrinsically low levels of PINK1 and undetectable levels of phosphorylated Parkin in small *** this issue is critical for elucidating the in vivo roles of PINK1 and ***,we showed that the PINK1 kinase is selectively expressed as a truncated form(PINK1–55)in the primate *** the present study,we used multiple antibodies,including our recently developed monoclonal anti-PINK1,to validate the selective expression of PINK1 in the primate *** found that PINK1 was stably expressed in the monkey brain at postnatal and adulthood stages,which is consistent with the findings that depleting PINK1 can cause neuronal loss in developing and adult monkey ***1 was enriched in the membrane-bound fractionations,whereas Parkin was soluble with a distinguishable *** double staining experiments showed that PINK1 and Parkin did not colocalize under physiological conditions in cultured monkey astrocytes,though they did colocalize on mitochondria when the cells were exposed to mitochondrial *** findings suggest that PINK1 and Parkin may have distinct roles beyond their well-known function in mitophagy during mitochondrial damage.

关键词： neurodegeneration Parkin Parkinson’s disease PINK1 subcellular distribution

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