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Chinese Chemical Letters 2025年第2期36卷 461-464页

作者： Manyu Zhu Fei liang lie Wu Zihao li Chen Wang Shule liu Xiue Jiang State Key Laboratory of Electroanalytical Chemistry Changchun Institute of Applied ChemistryChinese Academy of Sciences School of Applied Chemistry and Engineering University of Science and Technology of China School of Materials Science and Engineering Sun Yat-sen University Research Center for Analytical Science College of ChemistryNankai University

Revealing the factors that affect the vibrational frequency of Stark probe at interface is a pre-requirement for evaluating the absolute interfacial electric *** using surface-enhanced infrared absorption(SEIRA) spectroscopy,attenuated total reflection (ATR) spectroscopy and molecular dynamics (MD),we reveal the assembled C≡N at gold nanofilm exhibits a reduced Stark tuning rate (STR) referring to the vibrational frequency shift in response to electric field comparing with the bulk which was regulated by the electron transfer between S and *** findings lead to a deeper understanding of the vibrational Stark effect at the interface and provide guidance for improving the interface electric field theory.

关键词： Attenuated total reflection spectroscopy Cyano group Stark tuning rate Surface-enhanced infrared spectroscopy Vibrational stark effect

Precision storage lifetime measurements of highly charged heavy ions in the CSRe storage ring using a Schottky resonator

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Nuclear Science and Techniques 2025年第1期36卷 150-160页

作者： Qian Wang Xin-liang Yan Guang-Yu Zhu Shahab Sanjari li-Jun Mao He Zhao Yuri Alitvinov Rui-Jiu Chen Meng Wang Yu-Hu Zhang You-Jin Yuan Jun-Xia Wu Hong-Yang Jiao Yue Yu Zu-Yi Chen Yin-fang Luo Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China University of Chinese Academy of Sciences Beijing 100049China GSI Helmholtzzentrum für Schwerionenforschung Planckstrasse 164291 DarmstadtGermany FH Aachen University of Applied Sciences Heinrich-Mussmann-Str.152428 JülichGermany

Schottky mass spectrometry utilizing heavy-ion storage rings is a powerful technique for the precise mass and decay half-life measurements of highly charged *** to the nondestructive ion detection features of Schottky noise detectors,the number of stored ions in the ring is determined by the peak area in the measured revolution frequency *** of their intrinsic amplitude-frequency characteristic(AFC),Schottky detector systems exhibit varying sensitivities at different *** low-energy electron-cooled stored ions,a new method is developed to calibrate the AFC curve of the Schottky detector system of the Experimental Cooler Storage Ring(CSRe)storage ring located in Lanzhou,*** the amplitude-calibrated frequency spectrum,a notable refinement was observed in the precision of both the peak position and peak *** a result,the storage lifetimes of the electron-cooled fully ionized^(56)Fe^(26+)ions were determined with high precision at beam energies of 13.7 and 116.4 MeV/u,despite of frequency drifts during the *** electron cooling was turned off,the effective vacuum condition experienced by the 116.4 MeV/u^(56)Fe^(26+)ions was determined using amplitude-calibrated spectra,revealing a value of 2×10^(−10)mbar,which is consistent with vacuum gauge readings along the CSRe *** method reported herein will be adapted for the next-generation storage ring of the HIAF facility under construction in Huizhou,*** can also be adapted to other storage ring facilities worldwide to improve precision and enhance lifetime measurements using many ions in the ring.

关键词： lifetime measurement Schottky mass spectrometry Sensitivity response Highly charged heavy ion Resonator UH vacuum Nondestructive diagnostics

Causal relationship between lipid profile and muscle atrophy:A bi-directional Mendelian randomization study

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Animal Models and Experimental Medicine 2025年第1期8卷 154-161页

作者： Kun Chen Peng Gao Xiaoxiang fang Kexing Tang Pan Ouyang Zongchao li liangjun li Zhenhan Deng Department of Orthopaedics The Affiliated Changsha Central HospitalHengyang Medical SchoolUniversity of South ChinaChangshaHunanChina Department of Orthopaedic Surgery The First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiangChina

Background:The aim of this study was to analyze the bi-directional causal relation-ship between lipid profile and characteristics related to muscle atrophy by using a bi-directional Mendelian randomization(MR)***:The appendicular lean mass(ALM),whole body fat-free mass(WBFFM)and trunk fat-free mass(TFFM)were used as genome-wide association study(GWAS)data for evaluating muscle mass;the usual walking pace(UWP)and low grip strength(LGS)were used as GWAS data for evaluating muscle strength;and the triglycerides(TG),total cholesterol(TC),high density lipoprotein cholesterol(HDL),low density lipo-protein cholesterol(LDL),apolipoprotein A-1(Apo A-1),and apolipoprotein B(Apo B)were used as GWAS data for evaluating lipid *** specific investigations,we mainly employed inverse variance weighting for causal estimation and MR-Egger for pleiotropy ***:MR results showed that the lipid profile predicted by genetic variants was negatively correlated with muscle mass,positively correlated with UWP,and was not causally correlated with *** the other hand,the muscle mass predicted by genetic variants was negatively correlated with lipid profile,the UWP predicted by genetic variants was mainly positively correlated with lipid profile,while the LGS pre-dicted by genetic variants had no relevant causal relationship with lipid ***:Findings of this MR analysis suggest that hyperlipidemia may affect muscle mass and lead to muscle atrophy,but has no significant effect on muscle *** the other hand,increased muscle mass may reduce the incidence of dyslipidemia.

关键词： lipid profile Mendelian randomization muscle atrophy

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基于模糊关系的导弹武器装备故障诊断

弹箭与制导学报 2005年第S7期25卷 313-314页

作者：李良芳刘晓东李庆空军工程大学工程学院西安710038

文中以故障诊断理论和方法为基础,运用模糊理论,对复杂的导弹武器装备的故障诊断进行研究。提出了基于模糊关系的故障诊断的方法,建立了模糊关系故障诊断模型。该模型通过对已知故障的学习,获得专家的经验、知识和对故障危害度的协调能... 详细信息

文中以故障诊断理论和方法为基础,运用模糊理论,对复杂的导弹武器装备的故障诊断进行研究。提出了基于模糊关系的故障诊断的方法,建立了模糊关系故障诊断模型。该模型通过对已知故障的学习,获得专家的经验、知识和对故障危害度的协调能力,从而减低了诊断过程中的人为因素影响,较好地保证了诊断结果的客观性和正确性。

关键词：故障诊断模糊理论导弹武器装备

Glacier lake outburst floods(GLOF)susceptibility in the Boqu Basin in Tibetan Plateau

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Journal of Mountain Science 2025年第2期22卷 505-520页

作者： XU Shuai SU Peidong liang Yu li Yougui LONG Wei XU Mingshan School of Geoscience and Technology Southwest Petroleum UniversityChengdu 610500China Survey and Design Corporation of Power China Chengdu Engineering Corporation limited Chengdu 611130China

The glacial lake in the Boqu Basin in Tibetan Plateau has changed significantly in recent years due to global warming,seriously affecting the natural and social environments in downstream *** obtained the change characteristics of glacial lakes by analyzing remote sensing images and evaluated the outburst floods susceptibility of glacial lakes in the Boqu Basin by combining fuzzy mathematics and random forest *** empirical formula for glacial lake hazard evaluation was established based on a fuzzy comprehensive *** confusion matrix were used to assess the evaluation effect of each *** conclusions were as follows:(1)Under the influence of climate warming,glaciers are retreating further from the glacial lakes,and the size of glaciers that can impact these lakes is *** conditions,such as steep slopes around the lakes,have replaced glacier tongues as the primary factors threatening the susceptibility of the glacial lakes;(2)Among the three evaluation methods,the empirical formula offers high calculation accuracy and is the most convenient to use,which provides an accuracy rate of 85.71%in susceptibility evaluation of the Boqu Basin glacial lake and can be applied to other areas in the rapid evaluation of the susceptibility of glacial lakes;(3)The impact analysis of the collapse shows that the collapse of the Galongco fault would cause large economic losses.

关键词： Glacial lake change Hazard assessment Fuzzy comprehensive evaluation Random forest

Advances in regional-scale crop growth and associated process modeling

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Science China Earth Sciences 2025年第3期68卷 653-668页

作者： Wenfeng liU Yawei BAI Taisheng DU Mengxue li Hong YANG Shichao CHEN Chuanbin liang Shaozhong KANG State Key Laboratory of Efficient Utilization of Agricultural Water Resources China Agricultural University National Field Scientific Observation and Research Station on Efficient Water Use of Oasis Agriculture in Wuwei of Gansu Province Center for Agricultural Water Research in China China Agricultural University 2w2e Environmental Consulting GmbH

In the context of global change, ensuring national food security and achieving sustainable development of agricultural production systems have become major challenges worldwide. To address these issues, regional-scale crop growth and associated process(CROP-AP) models, with their robust simulation and predictive capabilities, have emerged as important tools for studying a wide range of issues relating to agricultural production at river basin, national, and even global scales. Here, we provide a systematic review of the advances of regional-scale CROP-AP models. First, regional-scale CROP-AP models are categorized based on model characteristics: statistical models, crop growth models, hydrology-crop coupling models, and ecosystem models. The origin, development, principle, structure, and application of each model type are introduced. Then, the main functions of regional-scale CROP-AP models are critically reviewed from five aspects: crop yield prediction, crop water consumption, agricultural non-point source pollution, greenhouse gas emissions, and climate change impact and ***, the future development trends and research priorities of regional-scale CROP-AP models are explored from six key perspectives: model validation and calibration, the ability to simulate the coupling of crop physiology and human activities,enhancing model scalability, multi-model ensembles, data and code sharing, and the integration of artificial intelligence. This review aims to provide comprehensive references and insights for the further development and application of large-scale, high-precision CROP-AP models.

关键词： Regional scale Crop model Biophysical processes Model functions Global change

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Stability Improvement Method for Multi-Converter Distribution Systems Based on Impedance Sensitivity

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CSEE Journal of Power and Energy Systems 2025年第1期11卷 318-328页

作者： Yang li Zhikang Shuai Junbin fang Xiangyang Wu College of Electrical and Information Engineering Hunan UniversityChangsha410082China

This paper uses impedance sensitivity to identify the parameters that have dominant influences on the stability of multi-converter systems, which can then efficiently improve system stability. A modified 400 V IEEE 13-bus system with three converters is used as the study case, and a stability improvement method for multi-converter systems according to impedance sensitivity is introduced. Sensitivities of the real and imaginary parts of eigenvalues of the system's return-ratio matrix with respect to parameters (including control parameters and grid component parameters) are calculated at the cross-over frequencies, by which the parameters that have dominant influences on the system stability can be identified. Then, according to sensitivities, the system stability can be efficiently improved by adjusting the dominant parameters. Simulations in PSCAD/EMTDC and experiments of the control hardware in the loop validate the effectiveness of the proposed stability analysis method.

关键词： Converter impedance sensitivity small-signal model stability analysis stability improvement.

Development and validation of a nomogram prediction model for overall survival in patients with rectal cancer

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World Journal of Gastrointestinal Oncology 2025年第2期17卷 93-104页

作者： ling liang Xiao-Sheng li Ze-Jun Huang Zu-Hai Hu Qian-Jie Xu Yu-liang Yuan Wei Zhang Hai-Ke Lei Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment Chongqing University Cancer HospitalChongqing 400030China Chongqing Cancer Multiomics Big Data Application Engineering Research Center Chongqing University Cancer HospitalChongqing 400030China Department of Health Statistics School of Public HealthChongqing Medical UniversityChongqing 400016China

BACKGROUND Rectal cancer is prevalent and associated with substantial morbidity and *** To develop a nomogram prediction model for overall survival(OS)in patients with rectal cancer by leveraging a comprehensive analysis of demographic,clinicopathological,haematological,and follow-up data to identify independent prognostic *** We conducted a prospective cohort study in China involving rectal cancer patients and applied Cox regression and least absolute shrinkage and selection operator regression to assess the significance of various variables as independent prognostic factors for *** identified factors were integrated into a nomogram model,which was evaluated for predictive accuracy via the C-index,area under the curve(AUC),calibration curve,and decision curve analysis(DCA).RESULTS Multivariate analysis revealed independent predictors of OS,including the Karnofsky performance status,age,sex,TNM stage,chemotherapy,surgery,targeted therapy,β2-microglobulin,lactate dehydrogenase,and the neutrophil-to-lymphocyte *** nomogram demonstrated a C-index of 0.80 for the training and validation cohorts,with AUC values indicating high predictive accuracy for 1-year,3-year,and 5-year *** calibration curves confirmed the model's excellent agreement with the observed survival rates,and DCA revealed the superior clinical utility of the nomogram over the TNM staging *** In this study,a novel prognostic model that accurately predicts the OS of rectal cancer patients was *** model exhibited excellent discriminatory and calibration capabilities,thus offering a reliable tool for health care professionals to estimate patient survival.

关键词： Rectal cancer Overall survival Nomogram Prognosis

Unraveling the role of long non‑coding RNAs in chronic heat stress‑induced muscle injury in broilers

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Journal of Animal Science and Biotechnology 2025年第1期16卷 206-217页

作者： Zhen liu Yingsen liu Tong Xing Jiaolong li lin Zhang liang Zhao Yun Jiang Feng Gao College of Animal Science and Technology Key Laboratory of Animal Origin Food Production and Safety Guarantee of Jiangsu ProvinceJiangsu Collaborative Innovation Center of Meat Production and ProcessingQuality and Safety ControlNanjing Agricultural UniversityNanjing 210095People’s Republic of China Anhui Key Laboratory of livestock and Poultry Product Safety Engineering Institute of Animal Husbandry and Veterinary MedicineAnhui Academy of Agricultural SciencesHefei 230031China Institute of Agro‑Products Processing Jiangsu Academy of Agricultural SciencesNanjing 210014People’s Republic of China School of Food Science and Pharmaceutical Engineering Nanjing Normal UniversityNanjing 210023People’s Republic of China

Background Chronic heat stress(CHS)is a detrimental environmental stressor with a negative impact on the meat quality of ***,the underlying mechanisms are not fully *** study investigates the effects of CHS on long non-coding RNA(lncRNA)expression and muscle injury in broilers,with a focus on its implications for meat *** The results showed that CHS diminished breast muscle yield,elevated abdominal fat deposition,induced cellular apoptosis(Pliminating the confounding effect of feed intake,68 lncRNAs were identified,primarily associated with cellular growth and death,signal transduc-tion,and metabolic ***,the apoptosis-related pathway P53,lysosomes,and the fibrosis-related gene TGF-β2 were significantly upregulated by *** These findings indicate that chronic heat stress induces cellular apoptosis and muscle injury through lncRNA,leading to connective tissue accumulation,which likely contributes to reduced breast muscle yield and meat quality in broilers.

关键词： Apoptosis Broiler Chronic heat stress LncRNA Muscle

Stir-Fried Semen Armeniacae Amarum Suppresses Aristolochic AcidⅠ-Induced Nephrotoxicity and DNA Adducts

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Chinese Journal of Integrative Medicine 2025年第2期31卷 142-152页

作者： li Cheng-xian XIAO Xiao-he li Xin-yu XIAO Da-ke WANG Yin-kang WANG Xian-ling ZHANG Ping li Yu-rong NIU Ming BAI Zhao-fang School of Chinese Materia Medica Beijing University of Chinese MedicineBeijing(100102)China Department of Hepatology Military Institute of Chinese Materiathe Fifth Medical CentreGeneral Hospital of PLABeijing(100039)China National Key Laboratory of Kidney Beijing(100039)China School of Pharmacy Chengdu University of Traditional Chinese MedicineChengdu(610075)China School of Traditional Chinese Medicine Capital Medical UniversityBeijing(100069)China School of Traditional Chinese Medicine Southern Medical UniversityGuangzhou(510515)China Department of Pharmacy Medical Supplies Center of PLA General HospitalBeijing(100039)China Department of Military Patient Management the Fifth Medical Center of PLA General HospitalBeijing(100039)China Department of Hematology the Fifth Medical Center of Chinese PLA General HospitalBeijing(100071)China

Objective:To investigate the protective effects of stir-fried Semen Armeniacae Amarum(SAA)against aristolochic acidⅠ(AAⅠ)-induced nephrotoxicity and DNA adducts and elucidate the underlying mechanism involved for ensuring the safe use of Asari Radix et ***:In vitro,HEK293T cells overexpressing Flag-tagged multidrug resistance-associated protein 3(MRP3)were constructed by Lentiviral transduction,and inhibitory effect of top 10 common pairs of medicinal herbs with Asari Radix et Rhizoma in clinic on MRP3 activity was verified using a self-constructed fluorescence screening *** m RNA,protein expressions,and enzyme activity levels of NAD(P)H quinone dehydrogenase 1(NQO1)and cytochrome P4501A2(CYP1A2)were measured in differentiated Hepa RG *** toxicity after inhibition of AAⅠmetabolite transport was detected using cell counting kit-8 *** vivo,C57BL/6 mice were randomly divided into 5 groups according to a random number table,including:control(1%sodium bicarbonate),AAⅠ(10 mg/kg),stir-fried SAA(1.75 g/kg)and AAⅠ+stir-fried SAA(1.75 and 8.75 g/kg)groups,6 mice in each *** 7 days of continuous gavage administration,liver and kidney damages were assessed,and the protein expressions and enzyme activity of liver metabolic enzymes NQO1 and CYP1A2 were determined ***:In vivo,combination of 1.75 g/kg SAA and 10 mg/kg AAⅠsuppressed AAⅠ-induced nephrotoxicity and reduced d A-Ali formation by 26.7%,and these detoxification effects in a dose-dependent manner(Pliver adducts(Pliver and kidney dam

关键词： aristolochic acidⅠ stir-fried Semen Armeniacae Amarum detoxification principles of compatibility metabolic enzymes transporters