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Structure,ligands,and roles of GPR126/ADGRG6 in the development and diseases

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Genes & Diseases 2024年第1期11卷 294-305页

作者： Qi li Anran Huo Mengqi li Jiali wang Qiao Yin Lumiao Chen Xin chu Yuan Qin Yuwan Qi Yang li Hengxiang Cui Qifei Cong Institute of Neuroscience and Jiangsu Key Laboratory of Neuropsychiatric Diseases Soochow UniversitySuzhouJiangsu215123China Department of Neurology and Clinical Research Center of Neurological Disease The Second Affliated Hospital of Soochow UniversitySuzhouJiangsu 215004China Department of Nephrology The Second Affiliated Hospital of Soochow UniversitySuzhouJiangsu 215004China Department of Emergency Center The Second Affiliated Hospital of Nantong UniversityNantongJiangsu226001China Department of Neurology Huzhou Central HospitalThe Affiliated Huzhou HospitalZhejiang University School of MedicineHuzhouZhejiang 313000China Institute of Neuroscience State Key Laboratory of NeuroscienceCAS Center for Excellence in Brain Science and Intelligence TechnologyChinese Academy of SciencesShanghai 200031China Shanghai Key Laboratory of Psychotic Disorders Shanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghai 200030China

Adhesion G protein-coupled receptors(aGPCRs)are the second largest diverse group within the GPCR superfamily,which play critical roles in many physiological and patho-logical processes through cell-cell and cell-extracellular matrix *** adhesion GPCR Adgrg6,also known as GPR126,is one of the better-characterized ***126 was previously found to have critical developmental roles in Schwann cell maturation and its mediated myelination in the peripheral nervous system in both zebrafish and *** studies have extended our understanding of GPR126-mediated roles during develop-ment and in human *** this review,we highlighted these recent advances in GPR126 in expression profile,molecular structure,ligand-receptor interactions,and associated physiological and pathological functions in development and diseases.

关键词： Adhesion G protein-coupled receptor Function GPR126/Adgrg6 ligand Structure

Achieving high carrier mobility and low lattice thermal conductivity in GeTe-based alloys by cationic/anionic co-doping

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Rare Metals 2024年第6期43卷 2784-2795页

作者： Xiao-Qiang wang Xiao-Quan Hu Jun-Yan lin chu-Bin li Xiao-Tong Yu Qi-Yong Chen li-li Xi Qi-Shuo Yang Han li Ji-Ye Zhang Shuan-Kui li Kai Guo School of Physics and Materials Science Guangzhou UniversityGuangzhou 510006China Research Center for Advanced Information Materials(CAIM) Huangpu Research&Graduate School of Guangzhou UniversitySino-Singapore Guangzhou Knowledge CityGuangzhou510555China School of Materials Science and Engineering Shanghai UniversityShanghai 200444China Materials Genome Institute Shanghai UniversityShanghai 200444China School of Mechanical and Mining Engineering University of QueenslandBrisbaneQLD 4072Australia Key Laboratory of Si-Based Information Materials&Devices and Integrated Circuits Design Department of Education of Guangdong ProvinceGuangzhou 510006China

TheⅣ-Ⅵcompound GeTe is considered as a promising alternative to the toxic PbTe for high-efficiency mid-temperature thermoelectric ***,pristine GeTe suffers from a high concentration of Ge vacancies,resulting in an excessively high hole concentration(>1×10^(21)cm^(-3)),which greatly limits its thermoelectric *** address this issue,CuBiTe_(2)alloying is introduced to increase the formation energy of Ge vacancies in GeTe,thereby inhibiting the high carrier *** carrier scattering caused by the electronegativity difference between different elements is suppressed due to the similar electronegativity of Cu and Ge atoms.A relatively high hole mobility is obtained,which ultimately leads to a high power ***,by introducing Se as an alloying element at the anionic site in GeTe,dense point defects with mass/strainfield fluctuations are *** contributes to the strengthening of phonon scattering,thereby reducing the lattice thermal conductivity from 1.44 W·m^(-1)·K^(-1)for pristine GeTe to 0.28 W·m^(-1)·K^(-1)for Ge_(0.95)Cu_(0.05)Bi_(0.05)Te_(0.9)Se_(0.15)compound at 623 K.

关键词： GeTe Carrier mobility CuBiTe_(2)alloying Lattice thermal conductivity Thermoelectric properties

The Relationship Between the Atmospheric Environment and Road Traffic Fatalities — Shandong Province, China, 2012–2021

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China CDC weekly 2024年第13期6卷 267-271页

作者： Tao wang Jie chu Zhiying Yao li Yang Zilong Lu Ge Tian Xiaolei Guo Cunxian Jia Department of Epidemiology School of Public HealthCheeloo College of MedicineShandong UniversityJinanShandong ProvinceChina Department for Chronic and Non-Communicable Disease Control and Prevention Shandong Center for Disease Control and PreventionJinanShandong ProvinceChina

Introduction:This study aims to analyze the potential impact of the meteorological environment and air pollutants on road traffic ***:Road traffic fatality data in Shandong Province from 2012 to 2021 were obtained from the Population Death Information Registration Management *** and air pollutant data for the same period were collected from the *** Oceanic and Atmospheric Administration and the Ecological Environment Monitoring Center of Shandong Province,***’s correlation and ridge regression were used to analyze the impact of the meteorological environment and air pollutants on road traffic ***:From 2012 to 2021,there were 163,863 road traffic fatality *** results of the ridge regression analysis showed that the daily average temperature was negatively correlated with total fatalities and passengers and positively correlated with pedestrians,nonmotorized drivers,and motorized *** daily minimum temperature was negatively correlated with total fatalities and positively correlated with motorized *** daily maximum temperature was positively correlated with both pedestrian and nonmotorized *** daily accumulated precipitation was negatively correlated with *** duration was positively correlated with both nonmotorized and motorized *** particulate matter(PM_(10))and nitrogen dioxide(NO_(2))were positively correlated with total fatalities,pedestrians,and nonmotorized *** dioxide(SO_(2))was positively correlated with total fatalities but negatively correlated with nonmotorized drivers,passengers,and motorized ***:Atmospheric factors associated with the occurrence of road traffic fatalities include air temperature,daily accumulated precipitation,sunshine duration,and air pollutants such as PM_(10),NO_(2),and SO_(2).

关键词： Ecological dioxide sunshine

YOLO-O2E:A Variant YOLO Model for Anomalous Rail Fastening Detection

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Computers, Materials & Continua 2024年第7期80卷 1143-1161页

作者： Zhuhong chu Jianxun Zhang Chengdong wang Changhui Yang Department of Computer Science and Engineering Chongqing University of TechnologyChongqing400054China Institute of Flexible Electronics(Future Technologies) Xiamen UniversityXiamen361000China College of Mechanical Engineering Chongqing University of TechnologyChongqing400054China

Rail fasteners are a crucial component of the railway transportation safety *** fasteners,distinguished by their high length-to-width ratio,frequently encounter elevated failure rates,necessitating manual inspection and *** inspection not only consumes time but also poses the risk of potential *** the advancement of deep learning technology in rail fasteners,challenges such as the complex background of rail fasteners and the similarity in their states are *** have proposed an efficient and high-precision rail fastener detection algorithm,named YOLO-O2E(you only look once-O2E).Firstly,we propose the EFOV(Enhanced Field of View)structure,aiming to adjust the effective receptive field size of convolutional kernels to enhance insensitivity to small spatial ***,The OD_MP(ODConv and MP_2)and EMA(EfficientMulti-Scale Attention)modules mentioned in the algorithm can acquire a wider spectrum of contextual information,enhancing the model’s ability to recognize and locate ***,we collected and prepared the GKA dataset,sourced from real train *** testing on the GKA dataset and the publicly available NUE-DET dataset,our method outperforms general-purpose object detection *** the GKA dataset,our model achieved a mAP 0.5 value of 97.6%and a mAP 0.5:0.95 value of 83.9%,demonstrating excellent inference ***-O2E is an algorithm for detecting anomalies in railway fasteners that is applicable in practical industrial settings,addressing the industry gap in rail fastener detection.

关键词： Rail fastening detection deep learning anomalous rail fastening variant YOLO feature reinforcement

ED-Ged:Nighttime Image Semantic Segmentation Based on Enhanced Detail and Bidirectional Guidance

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Computers, Materials & Continua 2024年第8期80卷 2443-2462页

作者： Xiaoli Yuan Jianxun Zhang Xuejie wang Zhuhong chu College of Computer Science and Engineering Chongqing University of TechnologyChongqing400054China

Semantic segmentation of driving scene images is crucial for autonomous *** deep learning technology has significantly improved daytime image semantic segmentation,nighttime images pose challenges due to factors like poor lighting and overexposure,making it difficult to recognize small *** address this,we propose an Image Adaptive Enhancement(IAEN)module comprising a parameter predictor(Edip),multiple image processing filters(Mdif),and a Detail Processing Module(DPM).Edip combines image processing filters to predict parameters like exposure and hue,optimizing image *** adopt a novel image encoder to enhance parameter prediction accuracy by enabling Edip to handle features at different *** strengthens overlooked image details,extending the IAEN module’s *** the segmentation network,we integrate a Depth Guided Filter(DGF)to refine segmentation *** entire network is trained end-to-end,with segmentation results guiding parameter prediction optimization,promoting self-learning and network *** lightweight and efficient network architecture is particularly suitable for addressing challenges in nighttime image *** experiments validate significant performance improvements of our approach on the ACDC-night and Nightcity datasets.

关键词： Night driving semantic segmentation nighttime image processing adverse illumination differentiable filters

Single-atom Co alloyed Ru for electrocatalytic nitrite reduction to ammonia

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Nano Research 2024年第5期17卷 3660-3666页

作者： Fuzhou wang Jiaqi Xiang Guike Zhang Kai Chen Ke chu School of Materials Science and Engineering Lanzhou Jiaotong UniversityLanzhou 730070China

Electrochemical converting NO_(2)^(-)into NH_(3)(NO_(2)RR)holds an enormous prospect to attain efficient NH_(3) electrosynthesis and polluted NO_(2)^(-)***,we report single-atom Co alloyed Ru(Co_(1)Ru)as an efficient and durable NO_(2)RR *** experimental and theoretical investigations reveal that single-atom Co alloying of Ru enables the construction of Co_(1)-Ru heteronuclear active sites to synergistically promote NO_(2)^(-)activation/hydrogenation while suppressing the competitive H_(2) evolution,rendering the greatly enhanced activity and selectivity of Co_(1)Ru towards the NO_(2)***,Co_(1)Ru assembled within a flow cell exhibits an impressive NH_(3) yield rate of 2379.2μmol·h^(-1)·cm^(-2) with an NH_(3)-Faradaic efficiency of 92%at a high current density of 415.9 mA·cm^(-2),which is among the highest NO_(2)RR performances reported to date.

关键词： electrochemical converting NO_(2)-into NH3 single-atom alloys theoretical computations industrial-level current density

Complete-basis-reprogrammable coding metasurface for generating dynamicallycontrolled holograms under arbitrary polarization states

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Opto-Electronic Advances 2024年第9期7卷 65-80页

作者： Zuntian chu Xinqi Cai Ruichao Zhu Tonghao liu Huiting Sun Tiefu li Yuxiang Jia Yajuan Han Shaobo Qu Jiafu wang Shaanxi Key Laboratory of Artificially-Structured Functional Materials and Devices Air Force Engineering UniversityXi’an 710051China Suzhou Laboratory Suzhou 215000China Zhijian Laboratory Rocket Force University of EngineeringXi’an 710025China.

Reprogrammable metasurfaces,which establish a fascinating bridge between physical and information domains,can dynamically control electromagnetic(EM)waves in real time and thus have attracted great attentions from researchers around the *** control EM waves with an arbitrary polarization state,it is desirable that a complete set of basis states be controlled independently since incident EM waves with an arbitrary polarization state can be decomposed as a linear sum of these basis *** this work,we present the concept of complete-basis-reprogrammable coding metasurface(CBR-CM)in reflective manners,which can achieve independently dynamic controls over the reflection phases while maintaining the same amplitude for left-handed circularly polarized(LCP)waves and right-handed circularly polarized(RCP)*** LCP and RCP waves together constitute a complete basis set of planar EM waves,dynamicallycontrolled holograms can be generated under arbitrarily polarized wave *** dynamically reconfigurable metaparticle is implemented to demonstrate the CBR-CM’s robust capability of controlling the longitudinal and transverse positions of holograms under LCP and RCP waves ***’s expected that the proposed CBR-CM opens up ways of realizing more sophisticated and advanced devices with multiple independent information channels,which may provide technical assistance for digital EM environment reproduction.

关键词： basis vector control reprogrammable metasurface dynamically-controlled holograms arbitrary polarization state broadband

The origins of catalytic selectivity for the electrochemical conversion of carbon dioxide to methanol

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Nano Research 2024年第1期17卷 5-17页

作者： Tian wang Yating wang Yuhang li chunzhong li Key Laboratory for Ultrafine Materials of Ministry of Education Shanghai Engineering Research Center of Hierarchical NanomaterialsFrontiers Science Center for Materiobiology and Dynamic ChemistrySchool of Materials Science and EngineeringEast China University of Science&TechnologyShanghai 200237China School of Chemical Engineering East China University of Science&TechnologyShanghai 200237China

The electrocatalytic conversion of carbon dioxide(CO_(2))into useful fuels and chemical feedstocks is an emerging route to alleviate global warming and reduce reliance on fossil ***(CH_(3)OH),as one of the most significant and widely used liquid fuels that can be generated by CO_(2)reduction,is essential in the chemical *** this minireview,we unravel the origins of the selective formation of CH_(3)OH via CO_(2)reduction,including catalyst composition designs,local structure modulations,and electrolyte/catalyst interface ***,the remaining challenges and perspectives for the CO_(2)-to-CH_(3)OH reduction are proposed.

关键词： methanol carbon dioxide(CO_(2))reduction reaction electrochemistry electrocatalyst catalyst-electrolyte interface

Development of EPDM composites reinforced by CNTs@SiO_(2)for thermal protection systems of aerospace propulsion:Significant improvement in oxidation and ablation resistance properties

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Chinese Journal of Aeronautics 2024年第2期37卷 471-481页

作者： li wang Jiang li Kang li Yiwei wang Chenyang MA Science and Technology on Combustion Internal Flow and Thermal-Structure LaboratoryNorthwestern Polytechnical UniversityXi’an 710072China

Carbon Nanotubes(CNTs)reinforced Polymer-Matrix Composites(PMCs)is widely used as insulation materials in thermal protection system of aerospace ***,CNTs are prone to oxidation and have high thermal conductivities,which makes it difficult to improve the ablation resistance of insulation materials that contain ***_(2)was encapsulated onto the surface of CNTs(CNTs@SiO_(2)),which were then added to Ethylene Propylene Diene Monomer(EPDM)rubber to prepare the insulation *** analysis and ablation test were used to evaluate the resistance of the insulation materials to thermal oxidation and ***,scanning electron microscopy was performed to analyze their *** revealed that the addition of CNTs@SiO_(2)could visibly reduce the effects of hot corrosion and ablation on insulation *** C-CNTs@SiO_(2)-1 formulation had the best ablative ***,compared with the unencapsulated formulation(C-CNTs-10),the C-CNTs@SiO_(2)-1 formulation reduced the line ablation rate by 51%to 0.0130 mm/s after oxygen-acetylene ***,the ablation mechanism was investigated based on the effects of the CNTs@SiO_(2)additive on their ***,the improvement in ablation performance may be attributed to CNTs@SiO_(2)-induced decreases in thermal conductivity,improvement in the hot corrosion resistance in the char layer,and changes in the microstructure.

关键词： Polymer-Matrix Composites(PMCs) Carbon Nanotubes(CNTs) Thermal properties Ablation Oxidation