检索结果-南通市图书馆

A systematic review of the role of TREM2 in Alzheimer’s disease

中华医学杂志(英文版) 2024年第14期137卷 1684-1694页

作者： Yin Yunsi Yang Hanchen li ruiyang Wu Guangshan Qin Qi Tang Yi Department of Neurology & Innovation Center for Neurological Disorders Xuanwu Hospital Capital Medical University National Center for Neurological Disorders Beijing China

Background: Given the established genetic linkage between triggering receptors expressed on myeloid cells 2 (TREM2) and Alzheimer’s disease (AD), an expanding research body has delved into the intricate role of TREM2 within the AD context. However, a conflicting landscape of outcomes has emerged from bothin vivo andin vitro investigations. This study aimed to elucidate the multifaceted nuances and gain a clearer comprehension of the role of ***: PubMed database was searched spanning from its inception to January 2022. The search criteria took the form of ( "Alzheimer’s disease" OR "AD" ) AND ( "transgenic mice model" OR "transgenic mouse model" ) AND ( "Triggering receptor expressed on myeloid cells" OR "TREM2" ). Inclusion criteria consisted of the following: (1) publication of original studies in English; (2) utilization of transgenic mouse models for AD research; and (3) reports addressing the subject of ***: A total of 43 eligible articles were identified. Our analysis addresses four pivotal queries concerning the interrelation of TREM2 with microglial function, Aβ accumulation, tau pathology, and inflammatory processes. However, the diverse inquiries posed yielded inconsistent responses. Nevertheless, the inconsistent roles of TREM2 within these AD mouse models potentially hinge upon factors such as age, sex, brain region, model type, and detection ***: This review substantiates the evolving understanding of TREM2’s disease progression-dependent impacts. Furthermore, it reviews the interplay between TREM2 and its effects across diverse tissues and temporal stages.

关键词： TREM2 Alzheimer’s disease Mouse model Microglia Amyloid-β accumulation Tau pathology Inflammation

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

特征提取与缩减在电力变压器异常状态检测的应用

引用

技术与市场 2024年第7期31卷 48-55页

作者：李瑞阳南京理工大学智能制造学院江苏南京210094

现有的三相干式变压器振动法状态检测,是一种利用从高频振动数据中提取特征,从而实现检测的方法。为了更准确地挖掘高频振动信号中的有效特征,提高诊断准确性,针对高频振动信号,将连续信号划分为独立的周期片段,从每一个周期中提取信号... 详细信息

现有的三相干式变压器振动法状态检测,是一种利用从高频振动数据中提取特征,从而实现检测的方法。为了更准确地挖掘高频振动信号中的有效特征,提高诊断准确性,针对高频振动信号,将连续信号划分为独立的周期片段,从每一个周期中提取信号的时域、频域和时频域特征;利用变压器振动原理分析,结合相关性分析给出特征选取策略;将筛选后的特征作为故障的特征值对振动进行实时的异常检测。结果表明:该方法可有效提取变压器振动信号特征,提高诊断准确率。

关键词：振动信号特征提取电力变压器异常检测

来源：

维普期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

基于Python+SQlite的文件整理软件设计与实现

引用

现代信息科技 2024年第1期8卷 28-31,38页

作者：李瑞洋周全兴凯里学院大数据工程学院贵州凯里556011

针对计算机中存储的文件日渐繁多,用于整理归纳的时间逐年上升的问题,采用Python中自带的os、date time、SQlite3、threading、hashlib和tkinter等数据库设计一款文件整理软件。该软件主要提供处理重复文件、提取目录下文件并重命名文... 详细信息

针对计算机中存储的文件日渐繁多,用于整理归纳的时间逐年上升的问题,采用Python中自带的os、date time、SQlite3、threading、hashlib和tkinter等数据库设计一款文件整理软件。该软件主要提供处理重复文件、提取目录下文件并重命名文件等功能。测试结果表明,该文件整理软件操作便捷,其整理效率远远高于传统整理方式,尤其是文件量大的情况下效果更明显。

关键词： Python SQlite数据库文件整理

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

An executable modeling and analyzing approach to C4ISR architecture

引用

Journal of Systems Engineering and Electronics 2020年第1期31卷 109-117页

作者： HE Hongyue ZHU Weixing li ruiyang DENG Qiaoyu Institute of Command and Control Engineering Army Engineering University of PLA

To analyze the behavioral model of the command,control,communication,computer,intelligence,surveillance,reconnaissance(C4ISR)architecture,we propose an executable modeling and analyzing approach to ***,the meta concept model of the C4ISR architecture is *** to the meta concept model,we construct the executable meta models of the C4ISR architecture by extending the meta models of ***,we define the concrete syntax and executable activity algebra(EAA)semantics for executable *** semantics functions are introduced to translating the syntax description of executable models into the item of *** support the execution of models,we propose the executable rules which are the structural operational semantics of ***,an area air defense of the C4ISR system is used to illustrate the feasibility of the approach.

关键词： command control communication computer intelligence surveillance reconnaissance(C4ISR)architecture meta model executable model algebraic semantics

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Physics-informed deep learning for solving phonon Boltzmann transport equation with large temperature non-equilibrium

引用

npj Computational Materials 2022年第1期8卷 245-254页

作者： ruiyang li Jian-Xun Wang Eungkyu Lee Tengfei Luo Department of Aerospace and Mechanical Engineering University of Notre DameNotre DameIN46556USA Department of Electronic Engineering Kyung Hee UniversityYongin-siGyeonggi-do17104South Korea Department of Chemical and Biomolecular Engineering University of Notre DameNotre DameIN46556USA Center for Sustainable Energy of Notre Dame(ND Energy) University of Notre DameNotre DameIN46556USA

Phonon Boltzmann transport equation(BTE)is a key tool for modeling multiscale phonon transport,which is critical to the thermal management of miniaturized integrated circuits,but assumptions about the system temperatures(i.e.,small temperature gradients)are usually made to ensure that it is computationally *** include the effects of large temperature non-equilibrium,we demonstrate a data-free deep learning scheme,physics-informed neural network(PINN),for solving stationary,mode-resolved phonon BTE with arbitrary temperature *** scheme uses the temperature-dependent phonon relaxation times and learns the solutions in parameterized spaces with both length scale and temperature gradient treated as input *** experiments suggest that the proposed PINN can accurately predict phonon transport(from 1D to 3D)under arbitrary temperature ***,the proposed scheme shows great promise in simulating device-level phonon heat conduction efficiently and can be potentially used for thermal design.

关键词： phonon equilibrium equation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effi ciency of Concrete Crack-healing based on Biological Carbonate Precipitation

引用

Journal of Wuhan University of Technology(Materials Science) 2015年第6期30卷 1255-1259页

作者：罗勉钱春香 li ruiyang RONG Hui College of Materials Science and Engineering Southeast University Research Institute of Green Construction Materials Southeast University

The aim of this study was to improve the capacity for crack-repair in concrete by developing a new way. The self-healing agent based on biological carbonate precipitation was developed. Crack-healing capacity of the cement paste specimens with this biochemical agent was researched. Scanning electron microscopy（SEM） and X-ray diffraction（XRD） were used to characterize the precipitation in *** healing efficiency was evaluated by measuring the water permeability after crack healing as *** experimental results show that the applied biochemical agent can successfully improve the self-healing capacity of the cement paste specimens as larger cracks can be healed. The cracks with a width of 0.48 mm in the specimens with the biochemical agent are nearly fully healed by the precipitation after 80 d repair. SEM and XRD analysis results demonstrate that the white precipitation in cracks is calcium carbonate, which displays spherical crystal morphology. Meanwhile, the water permeability test result shows that the biochemical agent can significantly decrease the water permeability of the cement paste specimens, the water permeability of specimens with the biochemical agent respectively decreases by 84% and 96% after 7 d and 28 d immersion in water, however the control specimens only respectively decrease by 41% and 60%, which indicates that the bacteria-based concrete appears to be a promising approach to increase concrete durability.

关键词： crack-healing capacity concrete bacteria self-healing agent water permeability

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

不同储存温度和时间对鸡蛋品质的影响

引用

畜禽业 2024年第7期35卷 9-14页

作者：李瑞阳郭艳张进良商丘师范学院生物与食品学院河南商丘476000

目的研究不同储存温度和储存时间对鸡蛋品质的影响。方法选取健康柴鸡蛋60枚分为A、B 2组,规模化养殖鸡蛋60枚分为C、D 2组,其中A、C组于4℃保存,B、D组于25℃保存,试验的第0、7、14、21、28天测定鸡蛋品质指标。结果在4℃下,储存时间(0... 详细信息

目的研究不同储存温度和储存时间对鸡蛋品质的影响。方法选取健康柴鸡蛋60枚分为A、B 2组,规模化养殖鸡蛋60枚分为C、D 2组,其中A、C组于4℃保存,B、D组于25℃保存,试验的第0、7、14、21、28天测定鸡蛋品质指标。结果在4℃下,储存时间(0~28 d)对柴鸡蛋和规模化养殖鸡蛋没有明显影响。在25℃,柴鸡蛋随着储存时间的延长,气室高度、蛋壳相对重、蛋黄相对重分别在第21、14、14天出现显著差异,蛋黄指数、浓蛋白含量、蛋清相对重分别在第7、28、28天出现显著差异。而规模化养殖鸡蛋在25℃随着储存时间的延长,气室高度在第21天出现显著差异,蛋黄指数、浓蛋白含量、蛋清相对重分别在第7、14、7天出现显著差异。结论鸡蛋在4℃储存时,能够有效延长鸡蛋的储存时间,且柴鸡蛋比规模化养殖鸡蛋耐储存。

关键词：储存温度储存时间鸡蛋品质

来源：

维普期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

椭圆曲线y^(2)=(x-2)(x^(2)+2x+m)的整数点

引用

沈阳大学学报（自然科学版） 2024年第2期36卷 179-184页

作者：曹雅丽杨海李瑞阳西安工程大学理学院陕西西安710048

设p是满足p≡5(mod12)的奇素数,q=p-3/2为奇素数或1,m为正整数且m=3p-8。运用初等数论的方法及四次丢番图方程的相关结果,给出了椭圆曲线y^(2)=(x-2)(x^(2)+2x+m)的所有整数点(x,y)。

关键词：椭圆曲线同余整数点勒让德符号四次丢番图方程

来源：

维普期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Distribution of Calcium Carbonate in the Process of Concrete Self-healing

引用

Journal of Wuhan University of Technology(Materials Science) 2016年第3期31卷 557-562页

作者：钱春香 li ruiyang LUO Mian CHEN Huaicheng School of Materials Science and Engineering Southeast UniversityNanjing 211189China Research Institute of Green Construction Materials Southeast UniversityNanjing 211189China

The complete deposition distribution process of calcium carbonate is summarized in three directions of cracks. Distribution of calcium carbonate in the self-healing process of microbial concrete is studied in detail, with the help of a variety of analytical techniques. The results show that carbonate deposits along the x-axis direction of the cracks. The farther from the crack surfaces of concrete matrix in x-axis direction, the more the content of the substrate, the less content of calcium carbonate. Gradual accumulation of calcium carbonate along the y-axis direction is like building a house with bricks. Different repair points are gradually connected, and ultimately the whole of cracks are completely filled. In the z-axis direction, calcium deposits on the surface of fracture direction, when the crack is filled on the surface, because the internal crack hypoxia in the depths of cracks hardly produces calcium carbonate.

关键词： microbial concrete cracks self-healing calcium carbonate deposition

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The critical need to establish standards for data quality in intelligent medicine

引用

Intelligent Medicine 2021年第2期1卷 49-50页

作者： ruiyang li Yahan Yang Haotian lin State Key Laboratory of Ophthalmology Zhongshan Ophthalmic CentreSun Yat-sen UniversityGuangzhouGuangdong 510623China Centre for Precision Medicine Sun Yat-sen UniversityGuangzhouGuangdong 510080China

Medical artificial intelligence(AI)is an important technical asset to support medical supply-side reforms and national development in the big data *** data from multiple disciplines represent building blocks for the development and application of AI-aided diagnostic and treatment systems based on medical big ***,the inconsistent quality of these data resources in AI research leads to waste and ***,it is crucial that the field formulatesthe requirements and content related to data processing as part of the development of intelligent *** promote medical AI research worldwide,the“Belt and Road”International Ophthalmic Artificial Intelligence Research and Development Alliance will establish a series of expert recommendations for data quality in intelligent medicine.

关键词： Artificial intelligence Intelligent medicine Big data Data collection Data storage Data management

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：