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The competition between Bidens pilosa and Setaria viridis alters soil microbial composition and soil ecological function

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Journal of Integrative Agriculture 2024年第1期23卷 267-282页

作者： qiao li Jianying Guo Han Zhang Mengxin Zhao State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijing 100193China College of life Science Yangtze UniversityJingzhou 434025China

Bidens pilosa is recognized as one of the major invasive plants in *** invasion has been associated with significant losses in agriculture,forestry,husbandry,and *** ecosystems play an important role in alien plant *** within the soil act as intermediaries between plants and soil ecological functions,playing a role in regulating soil enzyme activities and nutrient *** the interactions between invasive plants,soil microorganisms,and soil ecological processes is vital for managing and mitigating the impacts of invasive species on the *** this study,we conducted a systematic analysis focusing on *** and Setaria viridis,a common native companion plant in the invaded *** simulate the invasion process of ***,we constructed homogeneous plots consisting of *** and *** grown separately as monocultures,as well as in *** rhizosphere and bulk soils were collected from the alien plant *** and the native plant *** order to focus on the soil ecological functional mechanisms that contribute to the successful invasion of ***,we analyzed the effects of *** on the composition of soil microbial communities and soil ecological *** results showed that the biomass of *** increased by 27.51% and that of *** was significantly reduced by 66.56%.The organic matter contents in the bulk and rhizosphere soils of *** were approximately 1.30 times those in the native plant *** TN and NO_(3)^(-)contents in the rhizosphere soil of *** were 1.30 to 2.71 times those in the native plant *** activities of acid phosphatase,alkaline phosphatase,and urease in the rhizosphere soil of *** were 1.98-2.25 times higher than in the native plant *** high-throughput sequencing of the16S rRNA gene,we found that *** altered the composition of the soil microbial ***,many genera in Actinobacteria and Proteobacteri

关键词： plant invasion Bidens pilosa soil microbial composition soil properties soil enzyme activities

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Can Industrial Structure Upgrading Restrain Industrial Land Expansion?Evidence from China

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Chinese Geographical Science 2024年第3期34卷 504-518页

作者： CHEN Wei li qiao ZHANG Sun ZHOU Xue College of Economics and Management Northwest A&F UniversityYangling Shaanxi 712100China Institute of Geographic Sciences&Natural Resources Research Chinese Academy of SciencesBeijing 100101China

China has made great achievements in industrial development and is transforming into a powerful manufacturing ***,the industrial land scale is also ***,whether industrial structure upgrading achieves the purpose of restraining industrial land expansion remains *** calculating the industrial land structure index(ILSI)and industrial land expansion scale(ILES),this study analyzed their temporal and spatial distribution characteristics at both regional and city levels from 2007to 2020 in *** show that industrial land expansion presents a different trend in the four regions,the ILES in the eastern region is the largest,and the speed of industrial land expansion has declined since 2013,but it has gradually increased since *** ILSI of the eastern and central regions is higher than that of the western and northeastern ***,a spatial Durbin model(SDM)has been established to estimate the spatial effect of industrial structure upgrading on industrial land expansion from 2007 ***,industrial structure upgrading has not slowed industrial land *** eastern and western regions require a greater amount of industrial land while upgrading the industrial *** improvement of the infrastructure level and international trade level has promoted industrial land expansion.

关键词： industrial development industrial structure upgrading industrial land expansion regional differences China

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Responses of osteoblasts under varied tensile stress types induced by stretching basement materials

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International Journal of Smart and Nano Materials 2024年第2期15卷 279-295页

作者： Xuezheng Geng qiao li Yan Yao lizhen Wang Yubo Fan Beijing Advanced Innovation Center for Biomedical Engineering School of Biological Science and Medical EngineeringKey Laboratory of Biomechanics and Mechanobiology(Beihang University)Ministry of EducationBeijingChina School of Engineering Medicine Beihang UniversityBeijingChina

Osteoblasts are mechanosensitive *** stress with different conditions,including loading time,frequency,magnitude,*** cause varied responses in ***,it was not clarified that the effect of the loading types on the *** this study,we focused on the effect of varied tensile stress types on osteoblasts,including isotropic stretch,biaxial stretch,and uniaxial stretch with the negative ratio of transverse strain to axial strain(NR)-1,0,and 0.2 *** proliferation was determined to be most efficient when stimulated by 6%strain at a frequency of 1 Hz and a negative value of 0 for 1 h/*** varied strain resulted in a thickening of the F-actin cytoskeleton and a thinning of the *** flattening caused Yes-associated protein(YAP)to be transported to the *** was suggested that the influence of loading types on the mechanobiology responses must be *** mechanism of cell mechanical sensitivity under varied loading types was explored,which would provide good sugges-tions for designing microstructures to control deformation patterns in bone tissue engineering.

关键词： MC3T3-E1 tensile stress negative poisson’s ratio cell proliferation YAP

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Brain protective effect of dexmedetomidine vs propofol for sedation during prolonged mechanical ventilation in non-brain injured patients

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World Journal of Psychiatry 2024年第3期14卷 370-379页

作者： Hong-Xun Yuan li-Na Zhang Gang li li qiao Intensive Care Unit Peking University International HospitalBeijing 102206China Central Operating Room The Affiliated Beijing Chaoyang Hospital of Capital Medical UniversityBeijing 100020China

BACKGROUND Dexmedetomidine and propofol are two sedatives used for long-term *** remains unclear whether dexmedetomidine provides superior cerebral protection for patients undergoing long-term mechanical *** To compare the neuroprotective effects of dexmedetomidine and propofol for sedation during prolonged mechanical ventilation in patients without brain *** Patients who underwent mechanical ventilation for>72 h were randomly assigned to receive sedation with dexmedetomidine or *** Richmond Agitation and Sedation Scale(RASS)was used to evaluate sedation effects,with a target range of-3 to *** primary outcomes were serum levels of S100-βand neuron-specific enolase(NSE)every 24 *** secondary outcomes were remifentanil dosage,the proportion of patients requiring rescue sedation,and the time and frequency of RASS scores within the target *** A total of 52 and 63 patients were allocated to the dexmedetomidine group and propofol group,*** data were comparable between *** significant differences were identified between groups within the median duration of study drug infusion[52.0(IQR:36.0-73.5)h vs 53.0(IQR:37.0-72.0)h,P=0.958],the median dose of remifentanil[4.5(IQR:4.0-5.0)μg/kg/h vs 4.6(IQR:4.0-5.0)μg/kg/h,P=0.395],the median percentage of time in the target RASS range without rescue sedation[85.6%(IQR:65.8%-96.6%)vs 86.7%(IQR:72.3%-95.3),P=0.592],and the median frequency within the target RASS range without rescue sedation[72.2%(60.8%-91.7%)vs 73.3%(60.0%-100.0%),P=0.880].The proportion of patients in the dexmedetomidine group who required rescue sedation was higher than in the propofol group with statistical significance(69.2%vs 50.8%,P=0.045).Serum S100-βand NSE levels in the propofol group were higher than in the dexmedetomidine group with statistical significance during the first six and five days of mechanical ventilation,respectively(all P<0.05).CONCLUSION Dexmedetomidine demonstrated

关键词： Dexmedetomidine Propofol Sedation Prolonged mechanical ventilation Brain protective

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Photo-induced 1,2-aryl migration of 2-chloro-1-arylpropanone under batch and flow conditions:Rapid,scalable and sustainable approach to 2-arylpropionic acids

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Chinese Chemical Letters 2024年第2期35卷 366-369页

作者： qiao li Minjie liu Meifen Jiang li Wan Yingtang Ning Fen-Er Chen College of Chemical Engineering Zhejiang University of TechnologyHangzhou 310014China Engineering Center of Catalysis and Synthesis for Chiral Molecules Fudan UniversityShanghai 200433China Shanghai Engineering Center of Industrial Catalysis for Chiral Drugs Shanghai 200433China Institute of Pharmaceutical Science and Technology Zhejiang University of TechnologyHangzhou 310014China

We report the photo-mediated 1,2-aryl migration of 2‑chloro-1-arylpropanones to 2-arylpropionic acids using HCOONa as an acid *** pragmatically focused study obviates the multiple-step sequence in the industrially employed,ZnO-promoted rearrangement strategy,and offers rapid access to various 2-arylpropionic acids under environmentally friendly ***,the successful transfer of this batch photochemistry to a continuous flow platform led to improved scalability and enabled the gram-scale synthesis of loxoprofen.

关键词： Green chemistry Flow chemistry 2-Arylpropionic acids Photo-Favorskii reaction

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Recent advances in promising drugs for primary prevention of gastroesophageal variceal bleeding with cirrhotic portal hypertension

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Hepatobiliary & Pancreatic Diseases International 2024年第1期23卷 4-13页

作者： Ji-Yao Sheng Zi-Fan Meng qiao li Yong-Sheng Yang Department of Hepatobiliary and Pancreatic Surgery the Second Hospital of Jilin UniversityChangchun 130041China Jilin Engineering Laboratory for Translational Medicine of Hepatobiliary and Pancreatic Diseases the Second Hospital of Jilin UniversityChangchun 130041China

Background:Gastroesophageal variceal bleeding is one of the most severe complications of patients with *** primary prevention drugs,including non-selectiveβ-blockers,have effectively reduced the incidence of bleeding,their efficacy is limited due to side effects and related *** recent advances in precision medicine,precise drug treatment provides better treatment *** sources:literature search was conducted in PubMed,MEDliNE and Web of Science for relevant articles published up to May *** on clinical trials was obtained from https://***/and http://***/.Results:The in-depth understanding of the pathogenesis and advances of portal hypertension has enabled the discovery of multiple molecular targets for promising *** to the site of action,these drugs could be classified into four classes:intrahepatic,extrahepatic,both intrahepatic and extrahepatic targets and *** these classes of drugs offer advantages over traditional treatments in prevention of gastroesophageal variceal bleeding in patients with cirrhotic portal ***:This review classified and summarized the promising drugs,which prevent gastroesophageal variceal bleeding by targeting specific markers of pathogenesis of portal hypertension,demonstrating the significance of using the precision medicine strategy to discover and develop promising drugs for the primary prevention of gastroesophageal variceal bleeding in patients with cirrhotic portal hypertension.

关键词： Cirrhotic portal hypertension Target drug Primary prevention Bleeding

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Monte Carlo method for evaluation of surface emission rate measurement uncertainty

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Nuclear Science and Techniques 2024年第7期35卷 126-136页

作者： Yuan-qiao li Min lin li-Jun Xu Rui Luo Yu-He Zhang Qian-Xi Ni Yun-Tao liu China Institute of Atomic Energy Beijing102413China National Key Laboratory for Metrology and Calibration Techniques Beijing102413China Department of Radiation Oncology Hunan Cancer HospitalChangsha410031China The Affiliated Cancer Hospital of Xiangya School of Medicine Central South UniversityChangsha410031China

The aim of this study is to evaluate the uncertainty of 2πα and 2πβ surface emission rates using the windowless multiwire proportional counter *** study used the Monte Carlo method (MCM) to validate the conventional Guide to the Expression of Uncertainty in Measurement (GUM) method.A dead time measurement model for the two-source method was established based on the characteristics of a single-channel measurement system,and the voltage threshold correction factor measurement function was indirectly obtained by fitting the threshold correction *** uncertainty in the surface emission rate was calculated using the GUM method and the law of propagation of *** MCM provided clear definitions for each input quantity and its uncertainty distribution,and the simulation training was realized with a complete and complex mathematical *** results of the surface emission rate uncertainty evaluation for four radioactive plane sources using both methods showed the uncertainty’s consistency E_(n)lidation tool for GUM results.

关键词： Surface emission rate Monte Carlo method Metrology Probability distribution function Dead time Low-energy loss correction Least-squares method

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ZIF-8 modified by isocyanate as a photocatalytic antibacterial agent

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Rare Metals 2024年第6期43卷 2708-2718页

作者： Yi-Ning Zhang Zhen Pei Zi-Hao Wang Chong-En Wang Fen-Fen liang li-qiao Wei College of Architecture Taiyuan University of TechnologyTaiyuan 030024China Key Laboratory of Interface Science and Engineering in Advanced Materials of Taiyuan University of Technology Ministry of EducationTaiyuan 030024China Department of Materials Science and Engineering Shanxi Institute of TechnologyYangquan 045000China Shanxi-Zheda Institute of Advanced Materials and Chemical Engineering Taiyuan 030000China

Zeolite imidazole skeleton(ZIF-8)is a promising option for self-cleaning of building exterior walls due to its large specific surface area,high antibacterial activity and low ***,it suffers from low antibacterial efficiency and yield under visible light *** address the issues,we developed the photocatalytic materials T-ZIF-8-TDI(thermally treated-ZIF-8-toluene 2,4-diisocyanate)by modifying ZIF-8 with thermal oxygen sensitization and chemical *** results show that the yield of T-ZIF-8-TDI photocatalytic antibacterial agent is increased to 11.5 times of that of T-ZIF-8,while maintaining the crystal structure of T-ZIF-8 and thermal stability up to 60℃.Furthermore,T-ZIF-8-TDI exhibits extended optical response range to the nearinfrared region,significantly narrowed band gap,improved photogenerated elec tron-hole separation efficiency,reduced recombination rate,and excellent photocatalytic *** the concentration of antibacterial agent is 600 mg·L^(-1),the antibacterial rate of Escherichia coli(***)reaches 99.99%irradiated by visible light for30 min,and when the concentration of antibacterial agent is 200 mg·L^(-1),the antibacterial rate of Staphylococcus aureus(***)reaches 99.99%irradiated by visible light for 25 *** also analyzed the reasons in detail from the aspects of bacterial species and antibacterial mechanism,and proposed the antibacterial mechanism of·O_(2)^(-)and h^(+)as the main active *** findings suggest that T-ZIF-8-TDI photocatalytic antibacterial agent has potential for use in self-cleaning of building exterior walls.

关键词： ZIF-8 Hot oxygen sensitization Modified by isocyanate Antimicrobial performance Photocatalytic antibacterial mechanism

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Divergent Synthesis of Primary Amides via Modular Dearomative Carbamoylations of Areneπ-Systems

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CCS Chemistry 2024年第8期6卷 2066-2074页

作者： Chu-qiao li Xu Jiang Ming-Yang Wang Wei-Long Zeng Wei li Department of Chemistry Zhejiang UniversityHangzhou 310058

In sharp contrast to the well researched and well developed aminocarbonylation of alkenes,the dearomative carbamoylation of abundant areneπ-systems has scarcely been studied despite its great potential to enrich the diversity-oriented synthesis of high-value *** formidable challenges associated with such dearomatization include the low reactivity of stable aromaticπ-systems and intricate selectivity ***,we disclose a general approach toward highly selective dearomative carbamoylations of areneπ-bonds under CO-gas-free *** extraordinary versatility was demonstrated by tolerating a broad range of nucleophilic partners with high yields and excellent selectivities,thus providing modular access to the divergent synthesis ofβ-functionalized primary *** addition,diverse downstream derivatizations including a formal C–H 1,2-olefination/carbamoylation reaction were conducted,exhibiting great potential in synthetic and medicinal chemistry.

关键词： aminocarbonylation arene carbamoylation dearomatization primary amide

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Metabolic disorders and hepatitis: Insights from a Mendelian randomization study

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World Journal of Gastrointestinal Surgery 2024年第6期16卷 1775-1790页

作者： ling-Bo liang Xiang-Ping liu Ting-Rui Mao qiao-li Su General Practice Ward General Practice Medical CenterWest China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Department of Primary Health Care The Fourth People’s Hospital of Dazhu CountyDazhou 635100Sichuan ProvinceChina

BACKGROUND Hepatitis is a systemic disease that often results in various ***-bolic disorders,the most common comorbidities in clinical practice,were selected for this *** To investigate the causal relationship between comorbidities and hepatitis trea-tment *** A total of 23583378 single nucleotide polymorphisms from 1248743 cases and related summaries of genome-wide association studies were obtained from online public databases.A two-sample Mendelian randomization(MR)was performed to investigate causality between exposure[type 2 diabetes mellitus(T2D),hyperlipidemia,and hypertension]and outcome(chronic hepatitis B or C in-fections).RESULTS The data supported the causal relationship between comorbidities and hepatitis infections,which will affect the severity of hepatitis progression and will also provide a reference for clinical *** three exposures showed a link with progression of both hepatitis B(T2D,P=0.851;hyperlipidemia,P=0.596;and hypertension,P=0.346)and hepatitis C(T2D,P=0.298;hyperlipidemia,P=0.141;and hypertension,P=0.035).CONCLUSION The results of MR support a possible causal relationship between different ex-posures(T2D,hyperlipidemia,and hypertension)and chronic hepatitis progression;however,the potential mechanisms still need to be elucidated.

关键词： Hepatitis Comorbidity Type 2 diabetes mellitus Hyperlipidemia Hypertension

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