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“Phonon” scattering beyond perturbation theory

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Science China(Physics,Mechanics & Astronomy) 2016年第2期59卷 28-35页

作者： wu Jie Qiu Xue Zhi Ke li li Xi li hua wu Jiong Yang Wen Qing Zhang State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of Ceramics Chinese Academy of Sciences Department of Physics East China Normal University Materials Genome Institute Shanghai University

Searching and designing materials with intrinsically low lattice thermal conductivity （LTC） have attracted extensive considera- tion in thermoelectrics and thermal management community. The concept of part-crystalline part-liquid state, or even part-crystalline part-amorphous state, has recently been proposed to describe the exotic structure of materials with chemical-bond hierarchy, in which a set of atoms is weakly bonded to the rest species while the other sublattices retain relatively strong rigidity. The whole system inherently manifests the coexistence of rigid crystalline sublattices and fluctuating noncrystalline substructures. Representative materials in the unusual state can be classified into two categories, i.e., caged and non-caged ones. LTCs in both systems deviate from the traditional 7-1 relationship （T, the absolute temperature）, which can hardly be described by small-parameter-based perturbation approaches. Beyond the classical perturbation theory, an extra rattling-like scattering should be considered to interpret the liquid-like and sublattice-amorphization-induced heat transport. Such a kind of compounds could be promising high-performance thermoelectric materials, due to the extremely low LTCs. Other physical properties for these part-crystalline substances should also exhibit certain novelty and deserve further exploration.

关键词： part-crystalline state sublattice disorder lattice thermal conductivity

Optical Properties of Plasmon Resonances with Ag/SiO2/Ag Multi-Layer Composite Nanoparticles

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Chinese Physics Letters 2010年第6期27卷 107-109页

作者： MA Ye-Wan ZHANG li-hua wu Zhao-Wang ZHANG Jie School of Physics and Electric Engineering Anqing Teachers College Anqing 246011

Optical properties of plasmon resonance with Ag/SiO2/Ag multi-layer nanoparticles are studied by numerical simulation based on Green＇s function theory. The results show that compared with single-layer Ag nanoparticles, the multi-layer nanoparticles exhibit several distinctive optical properties, e.g. with increasing the numbers of the multi-layer nanoparticles, the scattering efficiency red shiRs, and the intensity of scattering enhances accordingly. It is interesting to find out that slicing an Ag-layer into multi-layers leads to stronger scattering intensity and more ＂hot spots＂ or regions of stronger field enhancement. This property of plasmon resonance of surface Raman scattering has greatly broadened the application scope of Raman spectroscopy. The study of metal surface plasmon resonance characteristics is critical to the further understanding of surface enhanced Raman scattering as well as its applications.

关键词：复合纳米粒子等离子体共振光学性能表面增强拉曼散射银纳米粒子格林函数理论散射强度共振拉曼散射

MIMO-OFDM detection based on Monte Carlo probabilistic data association

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The Journal of China Universities of Posts and Telecommunications 2007年第3期14卷 5-9页

作者： YANG Bin GONG Ping li Yong-hua wu Wei-ling Information Theory and Technology Education and Research Center Beijing University of Posts and Telecommunications Beijing 100876 China

This article proposes a spatial multiplexing and diversity joint transmit structure for multiple input multiple output（MIMO） - orthogonal frequency division multiplexing （OFDM） system. The structure uses space-frequency block coding （SFBC） over all its spatial multiplexing layers to obtain both space diversity and frequency diversity gain. The article derives a monte carlo probabilistic data association （PDA） detector to obtain a better bit error rate （BER） performance when compared to the generic PDA detector. Computer simulation results show that the proposed detector can reduce the inter-symbol interference（ISI） greatly, improve the system performance significantly, and lower the computation complexity to a proper lever.

关键词： MIMO OFDM Monte Carlo PDA

Madelung’s disease with alcoholic liver disease and acute kidney injury: A case report

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World Journal of Clinical Cases 2021年第27期9卷 8199-8206页

作者： ling wu Ting Jiang Yan Zhang An-Qi Tang li-hua wu Yu liu Ming-Quan li liang-Bin Zhao Department of Nephrology Hospital of Chengdu University of Traditional Chinese MedicineChengdu 610072Sichuan ProvinceChina Department of Ultrasound Hospital of Chengdu University of Traditional Chinese MedicineChengdu 610072Sichuan ProvinceChina

BACKGROUND Madelung’s disease(MD)is a rare disorder of lipid metabolism,characterized by the growth of unencapsulated masses of adipose tissue symmetrically deposited around the neck,shoulders,or other sites around the *** pathological mechanism is not yet *** of the most common comorbidities in MD patients is liver disease,especially chronic alcoholic liver disease(CALD);however,no reports exist of acute kidney injury(AKI)with *** SUMMARY We report a 60-year-old man who presented with complaint of edema in the lower limbs that had persisted for 3 *** examination showed subcutaneous masses around the neck,and history-taking revealed the masses to have been present for 2 years and long-term heavy *** the clinical symptoms,along with various laboratory test results and imaging characteristics,a diagnosis was made of MD with acute exacerbation of CALD and *** patient was treated with liver function protection and traditional Chinese medicine,without surgical *** was advised to quit *** 10 d,the edema had subsided,renal function indicators returned to normal,liver function significantly improved,and size of subcutaneous masses remained *** In MD,concomitant liver or kidney complications are possible and monitoring of liver and kidney functions can be beneficial.

关键词： Madelung’s disease Multiple symmetric lipomatosis Drinking Alcoholic liver disease Acute kidney injury Case report

Clinical efficacy analysis of mesenchymal stem cell therapy in patients with COVID-19:A systematic review

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World Journal of Clinical Cases 2022年第27期10卷 9714-9726页

作者： Jun-Xia Cao Jia You li-hua wu Kai Luo Zheng-Xu Wang Biotherapy Center The Seventh Medical Center of People's Liberation Army General HospitalBeijing 100700China

BACKGROUND Currently,ongoing trials of mesenchymal stem cells(MSC)therapies for coronavirus disease 2019(COVID-19)have been *** In this study,we investigated whether MSCs have therapeutic efficacy in novel COVID-19 *** Search terms included stem cell,MSC,umbilical cord blood,novel coronavirus,severe acute respiratory syndrome coronavirus-2 and COVID-19,applied to Pub Med,the Cochrane Controlled Trials Register,EMBASE and Web of *** A total of 13 eligible clinical trials met our inclusion criteria with a total of 548 *** analysis showed no significant decrease in C-reactive protein(CRP)levels after stem cell therapy(P=0.11).A reduction of D-dimer levels was also not observed in patients after stem cell administration(P=0.82).Furthermore,interleukin 6(IL-6)demonstrated no decrease after stem cell therapy(P=0.45).Finally,we investigated the overall survival(OS)rate after stem cell therapy in COVID-19 *** was a significant improvement in OS after stem cell therapy;the OS of enrolled patients who received stem cell therapy was 90.3%,whereas that of the control group was 79.8%(P=0.02).CONCLUSION Overall,our analysis suggests that while MSC therapy for COVID-19 patients does not significantly decrease inflammatory markers such as CRP,D-dimer and IL-6,OS is improved.

关键词： Stem cell Meta-analysis COVID-19 Mesenchymal stem cells

Relative bioavailability and pharmacokinetic comparison of two different enteric formulations of omeprazole

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2012年第5期13卷 348-355页

作者： Jian liU Jian-zhong SHENTU li-hua wu Jing DOU Qi-yang XU Hui-li ZHOU Guo-lan wu Ming-zhu huaNG Xing-jiang HU Jun-chun CHEN State Key Laboratory for Diagnosis and Treatment of Infectious Diseases Infectious Disease Centerthe First Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhou 310003China Research Center for Clinical Pharmacy the First Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhou 310003China

In order to comply with the requirements for a drug listed in China, the study was developed to compare the pharmacokinetics and relative bioavailability of two different enteric formulations of omeprazole (OPZ) in healthy Chinese subjects. A total of 32 volunteers participated in the study. Plasma concentrations were analyzed by non- stereospecific liquid chromatography/tandem mass spectrometric (LC-MS/MS) method. After administration of a single 40-mg dose of the two OPZ formulations, the comparative bioavailability was assessed by calculating individual AUC0-t (the area under the concentration-time curve from time zero to the last measurable concentration), AUC0-∞ (the area under the concentration-time curve extrapolated to infinity), Cmax (the maximum observed concentration), and Tpeak (the time to Cmax) values of OPZ, 5-hydroxyomeprazole (OH-OPZ), and omeprazole sulfone (OPZ-SFN), respectively. The 90% confidence intervals (CIs) of AUC0-t, AUC0-∞, and Cmax were 85.4%-99.0%/88.8%-98.6%/87.6%-99.4%, 85.5%-99.2%/89.0%-98.6%/88.5%-101.3%, and 72.3%-87.6%/79.6%-91.1%/88.4%-99.1% for OPZ/OH-OPZ/ OPZ-SFN, respectively, and Tpeak values did not differ significantly. In this study, the test formulation of OPZ in fasting healthy Chinese male volunteers met the Chinese bioequivalance standard to the reference formulation based on AUC, Cmax, and Tpeak.

关键词： Omeprazole 5-Hydroxyomeprazole Omeprazole sulfone Bioavailability Pharmacokinetics liquid chromatography/tandem mass spectrometry (LC-MS/MS)

Study of bedload transport in backwater flow

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Journal of Hydrodynamics 2016年第1期28卷 153-161页

作者：金中武卢金友吴华莉 Changjiang River Scientific Research Institute Wuhan 430010 China Collaborative Innovation Center for Geo-Hazards and Eco-Environment in Three Gorges Area Yichang 443002 China

This paper studies the flow structure and the bedload transport regime in backwater flows, to provide a theoretical support for solving the sediment transport and bed scour problems in rivers or reservoirs with backwater. The bedload transport rates under different conditions are analyzed first on the basis of theoretical analysis, measurement comparison and flume experiment, and it is pointed out that the existing formulas for the bedload transport rate are not applicable for the bedload transport rate in backwater flows. Next, the flow structure in a non-uniform flow is observed by flume experiments, and by introducing the backwater degree index, the quantitative relation between the relative bed shear stress and the backwater degree is obtained. Finally, the formula for the bedload transport rate applicable for the reservoir channel segment with backwater flows is obtained through measurements and flume experiments.

关键词： backwater flow bedload transport flume experiment formula for bedload transport rate

Effect of Nitrogen Applied Before Transplanting on NUE in Rice

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Agricultural Sciences in China 2007年第7期6卷 842-848页

作者： ZHENG Yong-mei DING Yan-feng WANG Qiang-sheng li Gang-hua wu Hao YUAN Qi WANG Hui-zhi WANG Shao-hua Key Laboratory of Crop Growth Regulation Ministry of Agriculture/Nanjing Agricultural University Nanjing 210095 P.R.China

Nitrogen （N） application before transplanting, where N fertilizers are applied in seedling-bed and carried to the paddy field with seedlings, is a novel method proposed in this article aiming for improving nitrogen utilization efficiency （NUE） in rice. The effect of this method on mineral N distribution in the rhizosphere soil was investigated in a field experiment with a japonica variety, Ningjing 2, in seasons of 2004 and 2005. There were four levels of N applied 16 h before transplanting： zero N （NO）, 207 kg ha^-1 （NL）, 310.5 kg ha^-1 （NM）, and 414 kg ha^-1 （NH）. The result indicated that N fertilizer before transplantation had positive effect of increasing mineral N content in the rhizosphere soil of rice. Generally, N content in the rhizosphere soil of rice tended to increase with the amount of N fertilizer before transplanting, with the NH treatment having the largest effect. Additionally, N fertilizer before transplanting had significant influence on rice NUE and grain yield. Compared with other treatments, the NM treatment showed the largest influence, with basal-tillering NUE, total NUE, and grain yield being 15%, 12%, and 529.5 kg ha^-1 higher than those of NO treatment. This result indicated that N fertilizer before transplantation had positive effect on mineral N distribution in the rhizosphere soil of rice, thus improving NUE and grain yield.

关键词： rice nitrogen (N) application before transplanting nitrogen utilization efficiency (NUE) grain yield

Antitumor effect of immunization with fusion of dendritic cells and hepatocellular carcinoma cells in mice

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Hepatobiliary & Pancreatic Diseases International 2004年第2期3卷 235-240页

作者： Hao Zhang Shu-Sen Zheng Guo-Ping Jiang li-hua wu Fen Zhu Zhen-lin Yang Department of Hepatobiliary Surgery First Affiliated Hospital Zhejiang University School of Medicine Hangzhou 310003 China. haozh@***

BACKGROUND:Important advances have made within the past few years in the treatment of hepatocellular carcinoma (HCC), however, the long-term prognosis after resection of HCC remains unsatisfactory as a result of a high incidence of recurrence. This study was to investigate immunization with fusions of DCs and HCC cells against HCC tumors transplanted to mice.METHODS:Fusion cells of dendritic cells (DCs) and H22 cells were prepared with polyethylene glycol. Expression of MHC and costimulatory molecules by dendritomas were determined by FACs. To study the antitumor immune preventitive and therapeutic effects, fusions were subcutaneously injected into naive or tumor-bearing mice; the CTL activity was assumed by the LDH method, and the expression of tumour necrosis factor-alpha (TNF-alpha) and interferon-gamma(IFN-gamma) in tumors were assayed by reverse transcription-polymerase chain reaction (RT-PCR).RESULTS:The hybridomas of DCs and H22 cells acquired both DCs and H22 cells phenotypes. Immunization of BALB/C mice with DC/H22 fusions induced protective immunity against a high dose of H22 tumor challenge. After treatment with hybridomas, the survival time of tumor-bearing mice was extended. The expression level of TNF-alpha and IFN-gamma mRNA was markedly increased.CONCLUSION:The hybridomas of DCs and H22 cells could induce effective antitumor immune responses and may be potentially used in prevention and management of recurrence and metastasis of HCC.

关键词： dendritic cells hepatocellular carcinoma cell fusion