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Visible light Indoor Positioning System Based on Pisarenko Harmonic Decomposition and Neural Network

Chinese Journal of electronics 2024年第1期33卷 195-203页

作者： li ZHAO Yi ReN Qi WANG Lange DeNG Feng ZHANG School of electronic Information engineering Xi’an Technological University

Visible-light indoor positioning is a new generation of positioning technology that can be integrated into smart lighting and optical communications. The current received signal strength(RSS)-based visible-light positioning systems struggle to overcome the interferences of background and indoor-reflected noise. Meanwhile, when ensuring the lighting, it is impossible to use the superposition of each light source to accurately distinguish light source information; furthermore, it is difficult to achieve accurate positioning in complex indoor environments. This study proposes an indoor positioning method based on a combination of power spectral density detection and a neural network. The system integrates the mechanism for visible-light radiation detection with RSS theory, to build a back propagation neural network model fitting for multiple reflection channels. Different frequency signals are loaded to different light sources at the beacon end, and the characteristic frequency and power vectors are obtained at the location end using the Pisarenko harmonic decomposition method. Then, a complete fingerprint database is established to train the neural network model and conduct location tests. Finally, the location effectiveness of the proposed algorithm is verified via actual positioning experiments. The simulation results show that, when four groups of sinusoidal waves with different frequencies are superimposed with white noise, the maximum frequency error is 0.104 Hz and the maximum power error is 0.0362 W. For the measured positioning stage, a 0.8 m × 0.8 m × 0.8 m solid wood stereoscopic positioning model is constructed, and the average error is 4.28 cm. This study provides an effective method for separating multi-source signal energies, overcoming background noise, and improving indoor visible-light positioning accuracies.

关键词： Neural networks Measurement uncertainty Position measurement Harmonic analysis light emitting diodes Frequency estimation Indoor positioning systems

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Leptin-mediated suppression of lipoprotein lipase cleavage enhances lipid uptake and facilitates lymph node metastasis in gastric cancer

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Cancer Communications 2024年第8期44卷 855-878页

作者： Jian Xiao Shuqing Cao Jiawei Wang Pengyu li Quan Cheng Xinyi Zhou Jiacheng Dong yuan li Xinyu Zhao Zekuan Xu li Yang Department of General Surgery The First Affiliated Hospital of Nanjing Medical UniversityNanjingJiangsuP.R.China

Background:Lymph node metastasis(LNM)is the primary mode of metastasis in gastric cancer(GC).However,the precise mechanisms underlying this process remain *** cells necessitate lipid metabolic reprogramming to facilitate metastasis,yet the role of lipoprotein lipase(LPL),a pivotal enzyme involved in exogenous lipid uptake,remains uncertain in tumor ***,the aim of this study was to investigate the presence of lipid metabolic reprogramming during LNM of GC as well as the role of LPL in this ***:Intracellular lipid levels were quantified using oil red O staining,BODIPY 493/503 staining,and flow *** analysis was employed to identify alterations in intracellular lipid composition following LPL *** expression levels were assessed through immunohistochemistry,Western blotting,and enzyme-linked immunosorbent *** mouse popliteal LNM model was utilized to investigate differences in *** and mass spectrometry were employed to examine protein *** vitro phosphorylation assays and Phos-tag sodium dodecyl-sulfate polyacrylamide gel electrophoresis assays were conducted to detect angiopoietin-like protein 4(ANGPTL4)***:We identified that an elevated intracellular lipid level represents a crucial characteristic of node-positive(N+)GC and further demonstrated that a high-fat diet can expedite *** was found to be significantly overexpressed in N+GC tissues and shown to facilitate LNM by mediating dietary lipid uptake within GC ***,an obesity-related hormone,intercepted the effect exerted by ANGPTL4/Furin on LPL *** leptin binding to the leptin receptor could induce the activation of inositol-requiring enzyme-1(IRe1)kinase,leading to the phosphorylation of ANGPTL4 at the serine 30 residue and subsequently reducing its binding affinity with ***,our research revealed that LPL disrupted lipid homeostasis by elevating intrace

关键词： angiopoietin-like protein 4 leptin lipoprotein lipase lymph node metastasis prostaglandin e2

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Two-Stage Planning of Distributed Power Supply and energy Storage Capacity Considering Hierarchical Partition Control of Distribution Network with Source-Load-Storage

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energy engineering 2024年第9期121卷 2389-2408页

作者： Junhui li yuqing Zhang Can Chen Xiaoxiao Wang Yinchi Shao Xingxu Zhu Cuiping li Key Laboratory of Modern Power System Simulation and Control&Renewable energy Technology Ministry of Education(Northeast Electric Power University)Jilin132012China State Grid Jibei electric Power Co. Ltd.Electric Power Research InstituteBeijing100045China

Aiming at the consumption problems caused by the high proportion of renewable energy being connected to the distribution network,it also aims to improve the power supply reliability of the power system and reduce the operating costs of the power *** paper proposes a two-stage planning method for distributed generation and energy storage systems that considers the hierarchical partitioning of ***,an electrical distance structural index that comprehensively considers active power output and reactive power output is proposed to divide the distributed generation voltage regulation domain and determine the access location and number of distributed power ***,a two-stage planning is carried out based on the zoning *** the phase 1 distribution network-zoning optimization layer,the network loss is minimized so that the node voltage in the area does not exceed the limit,and the distributed generation configuration results are initially determined;in phase 2,the partition-node optimization layer is planned with the goal of economic optimization,and the distance-based improved ant lion algorithm is used to solve the problem to obtain the optimal distributed generation and energy storage ***,the Ieee33 node systemwas used for *** results showed that the voltage quality was significantly improved after optimization,and the overall revenue increased by about 20.6%,verifying the effectiveness of the two-stage planning.

关键词： Zoning control two-stage planning site selection and capacity determination optimized scheduling improved ant lion algorithm

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Comparative DNA methylation reveals epigenetic adaptation to high altitude in snub-nosed monkeys

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Zoological Research 2024年第5期45卷 1013-1026页

作者： ling Wang Wei-Qiang liu Juan Du Meng li Rui-Feng Wu Ming li Key Laboratory of Animal ecology and Conservation Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China Center for excellence in Animal evolution and Genetics Chinese Academy of SciencesKunmingYunnan 650223China

DNA methylation plays a crucial role in environmental ***,using whole-genome bisulfite sequencing,we generated comprehensive genome-wide DNA methylation profiles for the high-altitude yunnan snub-nosed monkey(Rhinopithecus bieti)and the closely related golden snub-nosed monkey(***).Our findings indicated a slight increase in overall DNA methylation levels in golden snub-nosed monkeys compared to yunnan snub-nosed monkeys,suggesting a higher prevalence of hypermethylated genomic regions in the *** genomic methylation analysis demonstrated that genes associated with differentially methylated regions were involved in membrane fusion,vesicular formation and trafficking,hemoglobin function,cell cycle regulation,and neuronal *** results suggest that the high-altitude-related epigenetic modifications are extensive,involving a complete adaptation process from the inhibition of single Ca^(2+)channel proteins to multiple proteins collaboratively enhancing vesicular function or inhibiting cell differentiation and *** assays demonstrated that overexpression or down-regulation of candidate genes,such as SNX10,TIMeLeSS,and CACYBP,influenced cell viability under stress ***,this research suggests that comparing DNA methylation across closely related species can identify novel candidate genomic regions and genes associated with local adaptations,thereby deepening our understanding of the mechanisms underlying environmental adaptations.

关键词： Snub-nosed monkeys Whole-genome bisulfite sequencing DNA methylation High-altitude adaptation

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Three-dimensional electrically conductive–hydrophobic layer for stable Zn metal anodes

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SusMat 2024年第3期4卷 164-174页

作者： Yang Mei Jiahui Zhou Botao Zhang li li Feng Wu Yongxin Huang Renjie Chen Beijing Key Laboratory of environmental Science and engineering School of Material Science&EngineeringBeijing Institute of TechnologyBeijingChina Advanced Technology Research Institute(Jinan) Beijing Institute of TechnologyJinanChina Collaborative Innovation Center of electric Vehicles Beijing Institute of TechnologyBeijingChina

The interrelated side reactions and dendrites growth severely destabilize the electrode/electrolyte interfaces,resulting in the difficult application of aqueous Zn ion batteries(AZIBs).Hydrophobic protective layer possesses natural inhibition ability for side ***,the conventional protective layer with plane structure is difficult to attain joint regulation of side reaction and Zn ***,a novel three-dimensional(3D)electrically conductive and hydrophobic(3DeCH)interface is elaborated to enable stable Zn *** as-prepared 3DeCHinterface presents a uniform 3Dmorphologywith hydrophobic property,large specific surface area,abundant zincophilic sites,and excellent ***,the 3DeCH interface achieves uniform nucleation and dendrite-free deposition from synergetic benefits:(1)increased nucleation sites and reduced local current density through the special 3D structure and(2)uniform electric potential distribution and rapid Zn^(2+)transport due to the electroconductive alloy chemistry,thus coupling the hydrophobic property to obtain a highly reversible Zn ***,the modified anode achieves a superior coulombic efficiency of 99.88%over 3500 cycles,and the pouch cells using modified anode and liMn_(2)O_(4)(LMO)cathode retain a capacity of 84 mAh g^(−1)after 700 cycles at a reasonable depth discharge of 36%,without dendrite piercing and“dead Zn.”

关键词： electroconductive layer flat deposition hydrophobic layer three-dimensional surface zincmetal anode

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蛋黄冷冻凝胶化的产生原因及抑制方法的研究进展

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食品科学 2024年第21期45卷 39-47页

作者：杨田李凤红李鑫董世建李述刚黄群何雨贵州医科大学公共卫生与健康学院贵州省生态食品创制工程研究中心贵州贵阳550025 安徽荣达食品有限公司安徽宣城242200 合肥工业大学食品与生物工程学院安徽合肥230009

蛋黄是一个由多样化蛋白质组成的复杂的超分子结构体系,具有丰富的营养价值和突出的功能特性。冷冻保藏是工业上常用的延长蛋黄保质期、提高运输便捷性的有效方式。但在低温条件下,蛋黄内部的蛋白质会发生聚集,导致蛋黄凝胶化,从而出现... 详细信息

蛋黄是一个由多样化蛋白质组成的复杂的超分子结构体系,具有丰富的营养价值和突出的功能特性。冷冻保藏是工业上常用的延长蛋黄保质期、提高运输便捷性的有效方式。但在低温条件下,蛋黄内部的蛋白质会发生聚集,导致蛋黄凝胶化,从而出现流动性降低、溶解性下降等问题,影响其功能特性,不利于其在食品加工中的应用。本文介绍蛋黄的组成结构、功能特性,以及蛋黄冷冻原因和蛋黄凝胶化的形成机制,论述蛋黄的冷冻凝胶化对蛋黄品质的影响,重点阐述采用物理、化学和生物等方法对蛋黄进行预处理,抑制冷冻过程中蛋白质的聚集,对抑制蛋黄冷冻凝胶化的产生、改善冷冻蛋黄的品质具有指导意义。

关键词：蛋黄冷冻凝胶化品质劣变蛋白质聚集抑制方法

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Insight into the synergistic effect of defect and strong interface coupling on ZnIn_(2)S_(4)/CoIn_(2)S_(4)heterostructure for boosting photocatalytic H_(2) evolution

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Journal of energy Chemistry 2024年第5期92卷 151-161页

作者： Xuehua Wang Tianyu Shi Xianghu Wang Aili Song Guicun li Lei Wang Jianfeng Huang Alan Meng Zhenjiang li College of Materials Science and engineering Qingdao University of Science and TechnologyQingdao 266042ShandongChina Key Laboratory of Optic-electric Sensing and Analytical Chemistry for life Science MOECollege of Chemistry and Molecular EngineeringQingdao University of Science and TechnologyQingdao 266042ShandongChina Qingdao Huanghai University Qingdao 266000ShandongChina School of Material Science and engineering International S&T Cooperation Foundation of Shaanxi ProvinceXi’an Key Laboratory of Green Manufacture of Ceramic MaterialsShaanxi University of Science and TechnologyXi’an 710021ShaanxiChina

Steering the directional carrier migration across the interface is a central mission for efficient photocatalytic *** this work,an atomic-shared heterointerface is constructed between the defect-rich ZnIn_(2)S_(4)(HVs-ZIS)and CoIn_(2)S_(4)(CIS)via a defect-guided heteroepitaxial growth *** strong interface coupling induces adequate carriers exchanging passageway between HVs-ZIS and CIS,enhancing the internal electric field(IeF)in the ZnIn_(2)S_(4)/CoIn_(2)S_(4)(HVs-ZIS/CIS)*** defect structure in HVs-ZIS induces an additional defect level,improving the separation efficiency of ***,promoted by the IeF and intimate heterointerface,photogenerated electrons trapped by the defect level can migrate to the valence band of CIS,contributing to massive photogenerated electrons with intense reducibility in HVs-ZIS/***,the HVs-ZIS/CIS heterostructure performs a boosted H_(2)evolution activity of 33.65 mmol g^(-1)h^(-1).This work highlights the synergistic effects of defect and strong interface coupling in regulating carrier transfer and paves a brave avenue for constructing efficient heterostructure photocatalysts.

关键词： Defect-guided heteroepitaxial growth Heterointerface coupling Photocatalytic H_(2)evolution Mechanism HVs-ZIS/CIS

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effect of low-degree astigmatism on the objective visual quality

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International Journal of Ophthalmology(english edition) 2024年第6期17卷 1086-1093页

作者： ling-Ying Ye Shu-Feng li Jing-Jing Zuo Jin li Hui-Xiang Ma National Clinical Research Center for Ocular Diseases Eye HospitalWenzhou Medical UniversityWenzhou 325027Zhejiang ProvinceChina

AIM:To evaluate the effect of low-degree astigmatism on objective visual quality through the Optical Quality Analysis System(OQAS).MeTHODS:This study enrolled 46 participants(aged 23 to 30y,90 eyes)with normal or corrected-to-normal *** cylindrical lenses(0,0.5,0.75,1.0,and 1.25 D)were placed at the axial direction(180°,45°,90°,and 135°)in front of the eyes with the best correction to form 16 types of regular low-degree *** was used to detect the objective visual quality,recorded as the objective scattering index(OSI),OQAS values at contrasts of 100%,20%,and 9%predictive visual acuity(OV100%,OV20%,and OV9%),modulation transfer function cut-off(MTFcut-off)and Strehl ratio(SR).The mixed effect linear model was used to compare objective visual quality differences between groups and examine associations between astigmatic magnitude and objective visual quality ***:Apparent negative relationships between the magnitude of low astigmatism and objective visual quality were *** increase of OSI per degree of astigmatism at 180°,45°,90°,and 135°axis were 0.38(95%CI:0.35,0.42),0.50(95%CI:0.46,0.53),0.49(95%CI:0.45,0.54)and 0.37(95%CI:0.34,0.41),*** decrease of MTFcut-off per degree of astigmatism at 180°,45°,90°,and 135°axis were-10.30(95%CI:-11.43,-9.16),-12.73(95%CI:-13.62,-11.86),-12.75(95%CI:-13.79,-11.70),and-9.97(95%CI:-10.92,-9.03),*** the same astigmatism degree,OSI at 45°and 90°axis were higher than that at 0°and 135°axis,while MTFcut-off were ***:Low astigmatism of only 0.50 D can significantly reduce the objective visual quality.

关键词： low-degree astigmatism objective visual quality Optical Quality Analysis System

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Clinical significance of upregulated Rho GTPase activating protein 12 causing resistance to tyrosine kinase inhibitors in hepatocellular carcinoma

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World Journal of Gastrointestinal Oncology 2024年第10期16卷 4244-4263页

作者： Xiao-Wei Wang yu-Xing Tang Fu-Xi li Jia-Le Wang Gao-Peng Yao Da-Tong Zeng yu-Lu Tang Bang-Teng Chi Qin-Yan Su lin-Qing Huang Di-yuan Qin Gang Chen Zhen-Bo Feng Rong-Quan He Department of Pathology The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina Department of Pathology Red Cross Hospital of Yulin CityYulin 537000Guangxi Zhuang Autonomous RegionChi Department of Medical Oncology The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina Department of Computer Science and Technology School of Computer and Electronic InformationGuangxi UniversityNanning 530004Guangxi Zhuang Autonomous RegionChina

BACKGROUND Hepatocellular carcinoma(HCC)is a major health challenge with high incidence and poor survival rates in *** therapies,particularly tyrosine kinase inhibitors(TKIs),are the first-line treatment for advanced HCC,but resistance is *** Rho GTPase family member Rho GTPase activating protein 12(ARHGAP12),which regulates cell adhesion and invasion,is a potential therapeutic target for overcoming TKI resistance in ***,no studies on the expression of ARHGAP12 in HCC and its role in resistance to TKIs have been *** To unveil the expression of ARHGAP12 in HCC,its role in TKI resistance and its potential associated *** This study used single-cell RNA sequencing(scRNA-seq)to evaluate ARHGAP12 mRNA levels and explored its mechanisms through enrichment *** was used to investigate focal adhesion(FA)pathway *** integrated bulk RNA data(RNA-seq and microarray),immunohistochemistry and proteomics to analyze ARHGAP12 mRNA and protein levels,correlating with clinical *** assessed ARHGAP12 expression in TKI-resistant HCC,integrated conventional HCC to explore its mechanism,identified intersecting FA pathway genes with scRNA-seq data and evaluated its response to TKI and *** ARHGAP12 mRNA was found to be highly expressed in malignant hepatocytes and to regulate *** malignant hepatocytes in high-score FA groups,MDK-[integrin alpha 6(ITGA6)+integrinβ-1(ITGB1)]showed specificity in ligand-receptor ***12 mRNA and protein were upregulated in bulk RNA,immunohistochemistry and proteomics,and higher expression was associated with a worse ***12 was also found to be a TKI resistance gene that regulated the FA ***1 was identified as a crossover gene in the FA pathway in both scRNA-seq and bulk *** expression of ARHGAP12 was associated with adverse reactions to sorafenib,cabozantinib and regorafenib,but not to *** ARHGAP12 expre

关键词： Hepatocellular carcinoma Focal adhesion Tyrosine kinase inhibitor Rho GTPase activating protein 12 Drug resistance Molecular mechanism Biomarker

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Application and progress of artificial intelligence technology in the segmentation of hyperreflective foci in OCT images for ophthalmic disease research

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International Journal of Ophthalmology(english edition) 2024年第6期17卷 1138-1143页

作者： Jia-Ning Ying Hu li Yan-Yan Zhang Wen-Die li Quan-Yong Yi Ningbo eye Hospital Wenzhou Medical UniversityNingbo 315042Zhejiang ProvinceChina Health Science Center Ningbo UniversityNingbo 315211Zhejiang ProvinceChina

With the advancement of retinal imaging,hyperreflective foci(HRF)on optical coherence tomography(OCT)images have gained significant attention as potential biological biomarkers for retinal ***,these biomarkers,represented by HRF,present pose challenges in terms of localization,quantification,and require substantial time and *** recent years,the progress and utilization of artificial intelligence(AI)have provided powerful tools for the analysis of biological *** technology enables use machine learning(ML),deep learning(DL)and other technologies to precise characterization of changes in biological biomarkers during disease progression and facilitates quantitative *** on ophthalmic images,AI has significant implications for early screening,diagnostic grading,treatment efficacy evaluation,treatment recommendations,and prognosis development in common ophthalmic ***,it will help reduce the reliance of the healthcare system on human labor,which has the potential to simplify and expedite clinical trials,enhance the reliability and professionalism of disease management,and improve the prediction of adverse *** article offers a comprehensive review of the application of AI in combination with HRF on OCT images in ophthalmic diseases including age-related macular degeneration(AMD),diabetic macular edema(DMe),retinal vein occlusion(RVO)and other retinal diseases and presents prospects for their utilization.

关键词： artificial intelligence deep learning hyperreflective foci image analysis

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