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Anti-embolic effect of Taorenchengqi Tang in rats with embolic stroke induced by occluding middle cerebral artery

Journal of Traditional Chinese Medicine 2017年第3期37卷 326-332页

作者： li jiun-yi Chang Ting-Chen Chang Nen-Chung Thanasekaran Jayakumar Chang Chao-Chien Department of Cardiovascular Surgery MackayMemorial Hospitaland Mackay Medical CollegeTaipei10449Taiwan China Department of Lymphatic Vascular Surgery Wan Fang HospitalTaipei 116Taiwan China Department of Cardiology School ofMedicineTaipei Medical UniversityTaipei 110Taiwan China Department of Pharmacology and Graduate Institute of Medical Sciences College of MedicineTaipei Medical UniversityTaipei 110Taiwan China Department of Pharmacology and Graduate Institute of Medical Sciences College of MedicineTaipei Medical UniversityTaipei 110Taiwan China Depart-ment of Cardiology Cathay General HospitalTaipei 106Tai-wan China

OBJECTIVE: To investigate the anti-embolic effect of Taorenchengqi Tang(TRCQT), a formulas from Traditional Chinese Medicine, plus aspirin in rats with embolic stroke induced by selective occlusion of the middle cerebral artery(MCA). Possible side effects of hemorrhagic incident and other bleeding events and anti-platelet effect were also ***: Ninety rats were randomly separatedinto 9 groups(n = 10): group 1 a sham-operated group(n = 10); groups 2 and 3 orally treated with an isovolumetric solvent(distilled water) for 1 and3 months, followed by thromboembolic occlusion(n = 10); groups 4 and 5 orally treated with aspirin(5 mg/kg) alone for 1 and 3 months, followed by thromboembolic occlusion(n = 10); groups 6 and 7orally treated with TRCQT(0.5 g/kg) alone for 1 and3 months, followed by thromboembolic occlusion(n = 10); groups 8 and 9 orally treated with TRCQT plus aspirin for 1 and 3 months, respectively followed by thromboembolic occlusion(n = 10). The ischemic stroke in rats was induced by selective MCA occlusion. One was orally administered. After the treatments, rats' brains were removed, sectioned and stained with triphenyltetrazolium chloride(TTC) for infarct volume measurement. The incidence of subarachnoid hemorrhage(SAH) and intracerebral hemorrhage(ICH) were observed. A potential gastric bleeding side effect was assessed by measuring hemoglobin(Hb), and prothrombin time(PT). Collagen-induced platelet activation and tail vein bleeding time were ***: Treatment with TRCQT alone or in combination with aspirin reduced infarct volume for 1(P < 0.05), and 3(P < 0.01) months without SAH and ICH incidences, and gastric bleeding. TRCQT treatment for 1 month was also not altered PT. Moreover, a concentration dependent inhibition of collagen-induced platelet activation, followed by increasing of tail vein bleeding time was observed after TRCQT ***: Either TRCQT alone or TRCQT plus aspirin exhibits potent neuroprotective effect

关键词： Stroke Embolism Aspirin Subarach-noid hemorrhage Cerebral hemorrhage Prothrom-bin time Blood platelet Taorenchengqi Tang

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Self-assembly of perovskite nanocrystals:From driving forces to applications

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Journal of Energy Chemistry 2024年第1期88卷 561-578,I0013页

作者： yi li Fei Zhang School of Chemical Engineering and Technology Tianjin UniversityTianjin 300072China Collaborative Innovation Center of Chemical Science and Engineering(Tianjin) Tianjin 300072China

Self-assembly of metal halide perovskite nanocrystals(NCs)into superlattices can exhibit unique collective properties,which have significant application values in the display,detector,and solar cell *** review discusses the driving forces behind the self-assembly process of perovskite NCs,and the commonly used self-assembly methods and different self-assembly structures are ***,we summarize the collective optoelectronic properties and application areas of perovskite superlattice ***,we conclude with an outlook on the potential issues and future challenges in developing perovskite NCs.

关键词： Self-assembly Metal halide perovskite Nanocrystals Driving forces

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Embeddings Among Quantum Affine sl_(n)

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Acta Mathematica Sinica,English Series 2024年第3期40卷 792-805页

作者： yi Qiang li Department of Mathematics University at BuffaloThe State University of New YorkBuffaloNY 14260USA

We establish an explicit embedding of a quantum affine sl_(n) into a quantum affine sl_(n)+*** embedding serves as a common generalization of two natural,but seemingly unrelated,embed-dings,one on the quantum affine Schur algebra level and the other on the non-quantum *** embedding on the quantum affine Schur algebras is used extensively in the analysis of canonical bases of quantum affine sln and gl_(n).The embedding on the non-quantum level is used crucially in a work of Riche and Williamson on the study of modular representation theory of general linear groups over a finite *** same embedding is also used in a work of Maksimau on the categorical representations of affine general linear *** further provide a more natural compatibility statement of the em-bedding on the idempotent version with that on the quantum affine Schur algebra level.A gl_(n)-variant of the embedding is also established.

关键词： Quantum affine sl_(n) embeddings

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Transcriptomics and physiological analyses reveal that sulfur alleviates mercury toxicity in rice(Oryza sativa L.)

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Journal of Environmental Sciences 2024年第1期135卷 10-25页

作者： yingmei Huang Jicai yi Xiaomin li Fangbai li National-Regional Joint Engineering Research Center for Soil Pollution Control and Remediation in South China Guangdong Key Laboratory of Integrated Agro-Environmental Pollution Control and ManagementInstitute of Eco-Environmental and Soil SciencesGuangdong Academy of SciencesGuangzhou 510650China Guangzhou Institute of Geochemistry Chinese Academy of SciencesGuangzhou 510640China University of Chinese Academy of Sciences Beijing 100049China College of life Sciences South China Agricultural UniversityGuangzhou 510642China SCNU Environmental Research Institute Guangdong Provincial Key Laboratory of Chemical Pollution and Environmental Safety&MOE Key Laboratory of Theoretical Chemistry of EnvironmentSouth China Normal UniversityGuangzhou 510006China

Mercury(Hg)is one of the most dangerous contaminants and has sparked global concern since it poses a health risk to humans when consumed through ***(S)is a crucial component for plant growth,and S may reduce Hg accumulation in rice ***,the detailed effects of S and the mechanisms underlying S-mediated responses in Hg-stressed rice plants remain ***,to investigate the effects of S addition on rice growth,Hg accumulation,physiological indexes,and gene expression profiles,rice seedlings were hydroponically treated with Hg(20μmol/L Hg Cl_(2))and Hg plus elemental sulfur(100 mg/L).S application significantly reduced Hg accumulation in Hg-stressed rice roots and alleviated the inhibitory effects of Hg on rice growth.S addition significantly reduced Hg-induced reactive oxygen species generation,membrane lipid peroxidation levels,and activities of antioxidant enzymes while increasing glutathione content in *** analysis of roots identified 3,411,2,730,and 581 differentially expressed genes in the control(CK)***,CK ***+S,and Hg ***+S datasets,*** pathway of S-mediated biological metabolism fell into six groups:biosynthesis and metabolism,expression regulation,transport,stimulus response,oxidation reduction,and cell wall *** majority of biological process-related genes were upregulated under Hg stress compared with CK treatment,but downregulated in the Hg+S *** results provide transcriptomic and physiological evidence that S may be critical for plant Hg stress resistance and will help to develop strategies for reduction or phytoremediation of Hg contamination.

关键词： Sulfur Mercury Transcriptomics Detoxification

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Rainbow Pancyclicity in a Collection of Graphs Under the Dirac-type Condition

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Acta Mathematicae Applicatae Sinica 2024年第2期40卷 269-274页

作者： Lu-yi li Ping li Xue-liang li Center for Combinatorics and LPMC Nankai UniversityTianjin 300071China School of Mathematics and Statistics Shaanxi Normal UniversityXi’an 710062China

Let G={Gi:i∈[n]} be a collection of not necessarily distinct n-vertex graphs with the same vertex set V,where G can be seen as an edge-colored(multi)graph and each Gi is the set of edges with color i.A graph F on V is called rainbow if any two edges of F come from different Gis’.We say that G is rainbow pancyclic if there is a rainbow cycle Cℓof lengthℓin G for each integerℓ2[3,n].In 2020,Joos and Kim proved a rainbow version of Dirac’s theorem:Ifδ(Gi)≥2/n for each i∈[n],then there is a rainbow Hamiltonian cycle in *** this paper,under the same condition,we show that G is rainbow pancyclic except that n is even and G consists of n copies of Kn/2,n/*** result supports the famous meta-conjecture posed by Bondy.

关键词： rainbow Hamiltonian cycle rainbow pancyclic meta-conjecture

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Assessing clogging potential and optimizing driving parameter of slurry shield tunneling in clay stratum assisted with CFD-DEM modeling

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Underground Space 2024年第1期14卷 197-218页

作者： yi Yang Xing-gao li Han-yuan li yi-dong Guo ying-ran Fang Key Laboratory of Urban Underground Engineering of the Education Ministry Beijing Jiaotong UniversityBeijing 100044China School of Civil Engineering Beijing Jiaotong UniversityBeijing 100044China

This paper proposed a two-way coupled computational fluid dynamics(CFD)and discrete element method(DEM)approach to analyze the evolution of clogging in slurry shield tunneling *** interactions between clay particles and slurry were considered by exchanging three interaction forces,including buoyancy force,pressure gradient force,and drag *** CFD-DEM coupling approach was first benchmarked by comparing cutterhead torque and total thrust with field monitored data of a practical slurry shield tunnel *** evolution process of the particle phase and the fluid phase over time was *** results indicated that fewer than 70%of the particles can be washed away in time by the circulating *** 9%of the particles adhered to the submerged wall,resulting in increased cutterhead torque and *** parametric analysis,the influence of the shield driving parameters on the clay clogging behavior is further *** time history of cutterhead torque or thrust can be used as a criterion for judging whether clogging has ***,a new assessment method of clogging risk and an optimization strategy of driving parameters were proposed,which were intended to provide some guidance for similar projects.

关键词： Slurry shield Clogging Driving parameter optimization Assessment method CFD-DEM

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In memory of Robie ***(1948-2022):A scientist and a friend

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Environmental Science and Ecotechnology 2024年第2期18卷 4-6页

作者： yi-Fan li 不详

On February 17,2022,I received an email from Julie Henderson,the life partner of Robie *** her email,she conveyed the following message:"Hello yifan,Rob asked me to especially let you know that when he had *** admired and enjoyed working with you."As I read those words,tears welled up in my eyes,overwhelmed by profound *** was not only my scientific research colleague but also my closest *** had collaborated for more than two decades.

关键词： email friend partner

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Self-propelled Leidenfrost droplets on femtosecond-laser-induced surface with periodic hydrophobicity gradient

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International Journal of Extreme Manufacturing 2024年第2期6卷 502-509页

作者： Bohong li Lan Jiang Xiaowei li Zhipeng Wang Peng yi Laser Micro/Nano Fabrication Laboratory School of Mechanical EngineeringBeijing Institute of TechnologyBeijingPeople’s Republic of China Beijing Institute of Technology Chongqing Innovation Center ChongqingPeople’s Republic of China Yangtze Delta Region Academy of Beijing Institute of Technology JiaxingPeople’s Republic of China

The controllable transfer of droplets on the surface of objects has a wide application prospect in the fields of microfluidic devices,fog collection and so *** Leidenfrost effect can be utilized to significantly reduce motion ***,the use of 3D structures limits the widespread application of self-propulsion based on Leidenfrost droplets in microelectromechanical *** manipulate Leidenfrost droplets,it is necessary to create 2D or quasi-2D *** this study,femtosecond laser is applied to fabricate a surface with periodic hydrophobicity gradient(SPHG),enabling directional self-propulsion of Leidenfrost *** field analysis within the Leidenfrost droplets reveals that the vapor layer between the droplets and the hot surface can be modulated by the SPHG,resulting in directional propulsion of the inner *** viscous force between the gas and liquid then drives the droplet to move.

关键词： self-propelled Leidenfrost droplets periodic hydrophobicity gradient femtosecond laser fabrication

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Exploring changes of precipitation extremes under climate change through global variable-resolution modeling

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Science Bulletin 2024年第2期69卷 237-247页

作者： Wei Sun Jian li Rucong Yu Nina li yi Zhang State Key Laboratory of Severe Weather Chinese Academy of Meteorological SciencesBeijing 100081China Institute of Tibetan Plateau Meteorology China Meteorological AdministrationChengdu 610072China Department of Atmospheric Science Yunnan UniversityKunming 650091China National Meteorological Center China Meteorological AdministrationBeijing 100081China 2035 Future Laboratory PIESAT Information Technology Co.Ltd.Beijing 100105China

Understanding the responses of precipitation extremes to global climate change remains limited owing to their poor representations in models and complicated interactions with multi-scale *** we take the record-breaking precipitation over China in 2021 as an example,and study its changes under three different climate scenarios through a developed pseudo-global-warming(PGW)experimental framework with 60-3 km variable-resolution global ensemble *** to the present climate,the precipitation extreme under a warmer(cooler)climate increased(decreased)in intensity,coverage,and total amount at a range of 24.3%-37.8%(18.7%-56.1%).With the help of the proposed PGW experimental framework,we further reveal the impacts of the multi-scale system interactions in climate change on the precipitation *** the warmer climate,large-scale water vapor transport converged from double typhoons and the subtropical high marched into central China,enhancing the convective energy and instability on the leading edge of the transport *** a result,the mesoscale convective system(Mcs)that directly contributed to the precipitation extreme became stronger than that in the present *** the contrary,the cooler climate displayed opposite changing characteristics relative to the warmer climate,ranging from the large-scale systems to local environments and to the *** summary,our study provides a promising approach to scientifically assess the response of precipitation extremes to climate change,making it feasible to perform ensemble simulations while investigating the multi-scale system interactions over the globe.

关键词： Precipitation extreme Climate change Pseudo-global-warming experiment Variable-resolution modeling Multi-scale system interaction

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Fatigue-resistant Hydrogels

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Chemical Research in Chinese Universities 2024年第1期40卷 64-77页

作者： li Luofei LEI Hai CAO yi Collaborative Innovation Center of Advanced Microstructures National Laboratory of Solid State MicrostructureDepartment of PhysicsNanjing UniversityNanjing 210093P.R.China Department of Physics Zhejiang UniversityHangzhou 310027P.R.China

Hydrogels have been extensively studied for applications in various fields, such as tissue engineering and soft robotics, as determined by their mechanical properties. The mechanical design of hydrogels typically focuses on the modulus, toughness, and deformability. These characteristics play important roles and make great achievements for hydrogel use. In recent years, a growing body of research has concentrated on the fatigue property of hydrogels, which determines their resistance to crack propagation in the networks during cyclic mechanical loads for applications. However, knowledge of hydrogel fatigue behavior remains notably deficient. Here, we present a brief overview of the fatigue behavior of hydrogels, encompassing the general experimental methods to measure the fatigue property and fundamental theoretical calculation models. Then, we highlight multiple strategies to enhance the fatigue resistance of hydrogels. Finally, we present our perspectives on fatigue-resistant hydrogels, outstanding challenges and potential directions for future research.

关键词： Hydrogel Fatigue-resistant Fracture

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