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油气井地面管道防蚀的新方法

石油大学学报（自然科学版） 2004年第3期28卷 75-77页

作者：李洪波伍超郭素芬蒋代君郑永刚四川大学高速水力学国家重点实验室成都610065

基于多相流基础理论 ,采用原型观测与室内实验相结合的方法 ,研究了油气井生产及测试管道中多相流的流动过程。由于油嘴上游流体流速明显低于油嘴下游 ,提出了在油嘴上游对管道进行除砂防蚀的新思路。依据扩径沉砂、主流防砂、引流推砂... 详细信息

基于多相流基础理论 ,采用原型观测与室内实验相结合的方法 ,研究了油气井生产及测试管道中多相流的流动过程。由于油嘴上游流体流速明显低于油嘴下游 ,提出了在油嘴上游对管道进行除砂防蚀的新思路。依据扩径沉砂、主流防砂、引流推砂及稳定收砂的分离防蚀原则 ,设计了水平环空筛管分离装置捕砂器。使用结果表明 ,该装置具有很高的除砂率 ,防砂效果优于单纯地改进管道及附件材料的方法。

关键词：油气井油气管道防腐工艺分离设备捕砂器阻力系数

CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai Yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis bodrov Anton bogomyagkov Serge bondarenko Stewart boogert Maarten boonekamp Marcello borri Angelo bosotti Vincent boudry Mohammed boukidi Igor boyko Ivanka bozovic Giuseppe bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia hua Cai Wenyong Cai wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai huacheng Cai Lorenzo Calibbi Junsong Cang guofu Cao Jianshe Cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang Xinyuan Chang Wei chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen guoming Chen hua-Xing Chen Huirun Chen Jinhui Chen Ji-Yuan Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen Yukai Chen Zelin Chen Zilin Chen Gang Chen boping Chen Chunhui Chen Hok Chuen Cheng huajie Cheng Shan Cheng Tongguang Cheng Yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi ling-Yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong Jianin AGH university of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui university HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu university Institute of ScienceVaranasi Bandirma Onyedi Eylul university Bandirma Beihang university Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal university Beijing Brown university ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad university Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo university Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central china Normal university WuhanHubei Central South university ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan china academy of engineering physics MianyangSichuan china building materials academy Beijing china Center of Advanced Science and Technology Beijing china Institute of Atomic Energy Beijing china Jiliang university HangzhouZhejiang china Nuclear Instrument CO. LTDBeijing china university of Geosciences Beijing china university of Geosciences WuhanHubei china university of Mining and Technology XuzhouJiangsu china West Normal university NanchongSichuan Chongqing university Department of PhysicsChongqing Chulalongkorn university Bangkok City university of hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell university IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian Minzu university DalianLiaoning Dalian university of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna East china university Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by china,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV linac,a 1.1 GeV Damping Ring,a booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The linac and Damping Ring are situated on the surface,while the subterranean booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

棉花现代品种资源产量与纤维品质性状鉴定及分子标记评价

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作物学报 2024年第2期50卷 280-293页

作者：柯会锋苏红梅孙正文谷淇深杨君王国宁徐东永王洪这吴立强张艳张桂寅马峙英王省芬华北作物改良与调控国家重点实验室/河北省作物种质资源实验室/华北作物种质资源研究与利用教育部重点实验室/河北农业大学河北保定071001 河间市国欣农村技术服务总会河北河间062450

棉花是重要经济作物和天然纺织工业原料。品种是棉花生产的限制性源头,取决于优异种质资源的鉴定、评价和有效利用。鉴于此,本研究以我国三大棉区(黄河流域棉区、长江流域棉区和西北内陆棉区) 141份陆地棉现代品种资源为材料,在不同环... 详细信息

棉花是重要经济作物和天然纺织工业原料。品种是棉花生产的限制性源头,取决于优异种质资源的鉴定、评价和有效利用。鉴于此,本研究以我国三大棉区(黄河流域棉区、长江流域棉区和西北内陆棉区) 141份陆地棉现代品种资源为材料,在不同环境条件鉴定其9个产量与纤维品质性状,并结合KASP和SSR标记对其进行遗传多样性评价。结果发现,长江流域棉区品种的衣分和衣指最高,黄河流域棉区品种的单铃重和子指最大,西北内陆棉区品种的纤维品质最优;同时发现,4个产量性状与5个纤维品质性状在供试品种间存在极显著差异,产量性状以衣指的变异系数最大(10.09%),品质性状以断裂比强度的变异系数最大(8.81%),说明存在较大选择潜力。依据9个性状进行聚类分析,可将141份品种资源分为2类,且类别间的产量与品质性状存在差异。分子标记检测发现, 30对SSR引物在141份品种资源中扩增出74个多态性条带,32个KASP标记在供试品种中分型清晰,依据标记计算品种的遗传相似系数均值为0.62,说明存在较丰富遗传变异;分子标记聚类分析将供试品种分为2类,且分类结果与表型性状分类结果有一定相似性。本研究共筛选出3份大铃(>7 g)优异种质、24份高衣分(>42%)种质、6份纤维长度和断裂比强度>30的种质以及2份综合性状优异种质,为棉花新品种培育提供了优异亲本资源,为深入利用棉花品种资源提供了依据。

关键词：棉花种质资源产量和纤维品质分子标记遗传多样性

Transcriptome-wide association analysis identified candidate susceptibility genes for nasopharyngeal carcinoma

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Cancer Communications 2022年第9期42卷 887-891页

作者： Yong-Qiao He Wen-Qiong Xue Dan-hua li Tong-Min Wang Zhi-Ming Mai Da-Wei Yang Chang-Mi Deng Ying liao Wen-li zhang Ruo-Wen Xiao Luting Luo hua Diao Xiating Tong Yanxia wu Jiang-bo zhang ting Zhou Xi-Zhao li Pei-fen zhang Xiao-Hui Zheng Shao-Dan zhang Ye-Zhu Hu Minzhong Tang Yuming Zheng Yonglin Cai Ellen T.Chang Zhe zhang Guangwu huang su-Mei Cao Qing liu lin feng Ying sun Maria li Lung Hans-Olov Adami Weimin Ye Tai-Hing Lam Wei-hua Jia state key laboratory of Oncology in South china Collaborative Innovation Center for Cancer MedicineGuangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and TherapySun Yat-sen University Cancer CenterGuangzhouGuangdong 510060P.R.China School of Public Health Sun Yat-sen UniversityGuangzhouGuangdong 510080P.R.China School of Public Health The University of Hong KongHong Kong S.A.R.999077P.R.China Center for Nasopharyngeal Carcinoma Research Research Grants Council Area of Excellence SchemeThe University of Hong KongHong Kong S.A.R.999077P.R.China Radiation Epidemiology Branch Division of Cancer Epidemiology and GeneticsNational Cancer InstituteNational Institutes of HealthBethesdaMD 20892USA wuzhou Red Cross Hospital WuzhouGuangxi 543002P.R.China wuzhou Cancer Center WuzhouGuangxi 543002P.R.China Center for Health Sciences ExponentInc.Menlo ParkCA94025Department of Epidemiology and BiostatisticsUniversity of CaliforniaSan FranciscoCA 94143USA Department of Otolaryngology-Head and Neck surgery First Affiliated Hospital of Guangxi Medical UniversityNanningGuangxi 530021P.R.China Department of Radiation Oncology Sun Yat-sen University Cancer CenterState Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer MedicineGuangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and TherapyGuangzhouGuangdong 510060P.R.China Department of Clinical Oncology The University of Hong KongHong Kong S.A.R.999077P.R.China Clinical Effectiveness Group Institute of Health and SocietyUniversity of OsloOslo 0316Norway Department of Medical Epidemiology and Biostatistics Karolinska InstitutetStockholm 17177Sweden Department of Epidemiology and Health Statistics&key laboratory of Ministry of Education for Gastrointestinal Cancer Fujian Medical UniversityFuzhouFujian 350122P.R.China

Dear Editor,Nasopharyngeal carcinoma(NPC)is a common malignancy in East and Southeast Asia,especially in South *** etiology of NPC has been linked to genetic susceptibility,Epstein-Barr virus(EBV)infection,and environmental *** evidence including multiple genome-wide association studies(GWASs)has revealed robust genetic predisposition of ***,GWAS-identified genetic variants collectively account for only 8.2%of NPC heritability[1].The underlying inherited predisposition is largely *** strongest genetic signal for NPC consistently hits the human leukocyte antigen(HLA)region on 6p21[2].However,the highly polymorphic nature and complicated long-range linkage disequilibrium(LD)in the HLA region particularly obscure the causal variants driving the *** addition,most genetic variants located in introns or intergenic *** causal genes mediating genetic effects on NPC risk have rarely been ascertained by GWAS alone.

关键词： nasopharyngeal susceptibility collective

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道路雨水口水力特性的数值分析

水动力学研究与进展（A辑） 2020年第6期35卷 697-704页

作者：张珂侯精明宁利中马红丽张迪苏锋西安理工大学省部共建西北旱区生态水利国家重点实验室西安710048 鄂尔多斯市水利勘测设计院鄂尔多斯017000 中国电建西北勘测设计研究院有限公司西安710065

为了充分了解道路排水过程,掌握雨水口水力特性,利用商业软件Ansis FLUENT6.3分别对39组不同来流条件下的道路排水过程及雨水口水力特性进行精细模拟。并系统分析雨水口流态、流线及速度等分布特征。结果表明:雨水口的水力特性在其淹没... 详细信息

为了充分了解道路排水过程,掌握雨水口水力特性,利用商业软件Ansis FLUENT6.3分别对39组不同来流条件下的道路排水过程及雨水口水力特性进行精细模拟。并系统分析雨水口流态、流线及速度等分布特征。结果表明:雨水口的水力特性在其淹没前后分别以自由堰流形式和淹没堰流形式下泄。基于数值模拟数据以及量纲分析法,构建雨水口下泄流量系数与篦前水流的弗劳德数之间的经验公式Cw=-0.2755Fr^4+1.0755Fr^3-1.4745Fr^2+0.7609Fr-0.0215,决定系数R2=0.88,两者具有较高的相关性。该研究精确计算了道路排水过程,并通过模拟探究道路雨水口在不同入流条件下的泄流规律,有助于深化认识雨水口泄流过程,对指导城市内涝管理具有重要意义。

关键词：城市洪涝雨水口水力特性数值模拟

基于大肠杆菌表达的重组九价人乳头瘤病毒(HPV 6/11/16/18/31/33/45/52/58型)疫苗免疫原性和安全性的Ⅱ期临床试验

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Science Bulletin 2023年第20期68卷 2448-2455,M0006页

作者：胡月梅毕兆峰郑亚张黎郑凤珠储凯李亚飞陈祺全佳丽胡潇文黄兴成朱孔鑫王江雅慧姜汉民臧霞刘东林杨昌林潘红星张秋芬苏迎盈黄守杰孙光黄维金黄悦吴婷张军夏宁邵 Jiangsu Provincial Center for Disease Control and Prevention Public Health Research Institute of Jiangsu ProvinceNanjing 210009China state key laboratory of Vaccines for Infectious Diseases Xiang An Biomedicine LaboratorySchool of Public HealthXiamen UniversityXiamen 361102China National Institute of Diagnostics and Vaccine Development in Infectious Diseases State Key Laboratory of Molecular Vaccinology and Molecular DiagnosticsNational Innovation Platform for Industry-Education Integration in Vaccine ResearchNMPA Key Laboratory for Research and Evaluation of Infectious Disease Diagnostic TechnologyXiamen UniversityXiamen 361102China National Institutes for Food and Drug Control Beijing 102629China Xiamen Innovax Biotech Company Xiamen 361027China Dongtai Center for Disease Control and Prevention Yancheng 224200China

人乳头瘤病毒(HPV)16/18型双价疫苗(大肠埃希菌)已上市并通过世界卫生组织预认证.本研究通过一项随机双盲Ⅱ期临床试验评估其第二代HPV6/11/16/18/31/33/45/52/58型九价疫苗在18~45岁健康女性中的免疫原性和安全性.来自江苏省东台市的62... 详细信息

人乳头瘤病毒(HPV)16/18型双价疫苗(大肠埃希菌)已上市并通过世界卫生组织预认证.本研究通过一项随机双盲Ⅱ期临床试验评估其第二代HPV6/11/16/18/31/33/45/52/58型九价疫苗在18~45岁健康女性中的免疫原性和安全性.来自江苏省东台市的627名女性志愿者1:1随机分配至九价疫苗组(313人)或对照组(314人),并按照0、1、6月接种程序分别接种三剂1.0 mL(270μg)九价疫苗或空白佐剂,主要终点为第7月时血清抗体阳转率和抗体水平.结果显示,几乎所有疫苗组符合方案人群在第7月时出现针对9种HPV型别的血清中和抗体阳转,仅2人未发生HPV11型阳转,1人未发生HPV52型阳转.九价疫苗组和对照组的总体不良事件发生率分别为80.8%和72.9%,绝大多数不良事件症状轻微并很快恢复,未发生疫苗相关严重不良事件.该研究证明候选九价疫苗具有良好的安全性和免疫原性,支持在更大人群中进一步进行效力研究.

关键词： Ⅱ期临床试验免疫原性人乳头瘤病毒江苏省东台市双价疫苗大肠杆菌表达随机分配大肠埃希菌