检索结果-南通市图书馆

Therapeutic effects of adipose-derived stem cells-based microtissues on erectile dysfunction in streptozotocin-induced diabetic rats

引用

Asian Journal of Andrology 2017年第1期19卷 91-97页

作者： Feng Zhou Hua Xin Yong-De Xu Hong-En Lei Bi-Cheng Yang Rui-li guan Meng li Jian-Quan Hou Zhong-Cheng Xin Molecular Biology Laboratory of Andrology Center Peking University First Hospital Peking University Beijing 100034 China Department of Urology First Affiliated Hospital of Soochow University Soochow University Suzhou 215006 China Department of Ophthalmology Beijing Chao-Yang Hospital Capital Medical University Beijing 100043 China Department of Urology General Hospital of Ningxia Medical University Ningxia Medical University Ningxia 750021 China

This study aimed to explore the therapeutic effects of adipose-derived stem cells （ADSCs）-based microtissues （MTs） on erectile dysfunction （ED） in streptozotocin （STZ）-induced diabetic rats. Fifty-six 8-week-old Sprague-Dawley rats received intraperitoneal injection of STZ （60 mg kg-1）, and 8 weeks later, the determined diabetic rats randomly received intracavernous （IC） injection of phosphate buffer solution （PBS）, ADSCs, or MTs. Another eight normal rats equally got IC injection of PBS. MTs were generated with a hanging drop method, and the injected cells were tracked in ADSC- and MT-injected rats. Four weeks after the treatments, intracavernous pressure （ICP）, histopathological changes in corpus cavernosum （CC）, and functional proteins were measured. Rat cytokine antibody array was used to detect ADSCs or MTs lysate. The results showed that MTs expressed vascular endothelial growth factor （VEGF）, nerve growth factor （NGF）, and tumor necrosis factor-stimulated gene-6 （TSG-6）. MTs injection had a higher retention than ADSCs injection and MTs treatment improved ICP, neuronal nitric oxide synthase （nNOS） expression, smooth muscle, and endothelial contents in diabetic rats, ameliorated local inflammation in CC better. Thus, our findings demonstrate that IC injection of MTs improves erectile function and histopathological changes in STZ-induced diabetic rats and appears to be more promising than traditional ADSCs. The underlying mechanisms involve increased cell retention accompanied with neuroprotection and anti-inflammatory behaviors of the paracrine factors.

关键词： adipose-derived stem cells diabetes erectile dysfunction microtissues paracrine factors

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A Strong Law of Large Numbers for Set-Valued Random Variables in Gα Space

引用

Journal of Applied Mathematics and Physics 2015年第7期3卷 797-801页

作者： guan li College of Applied Sciences Beijing University of Technology Beijing China

In this paper, we shall represent a strong law of large numbers (SLLN) for weighted sums of set- valued random variables in the sense of the Hausdorff metric dH, based on the result of single-valued random variable ob... 详细信息

关键词： Set-Valued Random Variable the Laws of Large Numbers Hausdorff Metric

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A New Synthetical Model of High-Power Pulsed Laser Ablation

引用

Communications in Theoretical Physics 2007年第7期48卷 163-168页

作者： ZHANG Duan-Ming FANG Ran-Ran li Zhi-Hua guan li li li TAN Xin-Yu liU Dan liU Gao-Bin HU De-Zhi Department of Physics,Huazhong University of Science and Technology,Wuhan 430074,China Department of Physics Huazhong University of Science and Technology Wuhan 430074 China

We develop a new synthetical model of high-power pulsed laser ablation,which considers the dynamicabsorptance,vaporization,and plasma *** the corresponding heat conduction equations with the initial andboundary conditions are *** numerical solutions are obtained under the reasonable technical parameter condi-tions by taking YBa_2Cu_3O_7 target for *** space-dependence and time-dependence of temperature in targetat a certain laser fluence are presented,then,the transmitted intensity through plasma plume,space-dependence oftemperature and ablation rate for different laser fluences are significantly *** a result,the satisfactorily goodagreement between our numerical results and experimental results indicates that the influences of the dynamic absorp-tance,vaporization,and plasma shielding cannot be *** all the three mechanisms above simultaneouslyinto account for the first time,we cause the present model to be more practical.

关键词： pulsed laser ablation dynamic absorptance vaporization laser produced plasma

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Small balloon strategy associated with low pacemaker implantation rate after self-expanding transcatheter valve implantation

引用

World Journal of Emergency Medicine 2021年第1期12卷 48-53页

作者： Yuan Zhang Wen-zhi Pan li-hua guan Xiao-chun Zhang Sha-sha Chen li-fan Yang Lei Zhang Ming-fei li Dan-dan Chen Da-xin Zhou Jun-bo Ge Department of Cardiology Shanghai Institute of Cardiovascular DiseaseZhongshan HospitalFudan UniversityShanghai 200032China

BACKGROUND: This study aims to investigate whether small balloon aortic valvuloplasty(BAV) reduces the need for permanent pacemaker implantation (PPMI) after transcatheter aortic valveimplantation (TAVI).METHODS: This was a retrospective analysis using data from our local TAVI database. SmallBAV was defined as a small balloon size (=18 mm) pre-dilatation. Normal BAV was defined as aballoon size >18 mm. The primary endpoint was the incidence of new ***: Of 99 consecutive TAVI patients, five patients were excluded due to pre-existingpermanent pacemaker. Patients in the small BAV group (n=57) had a signifi cantly lower PPMI ratecompared with the normal BAV group (n=37) (3.5% vs. 18.9%, P=0.026). Moderate or severe aorticvalve regurgitation post-procedure was similar between the small BAV and normal BAV groups (5.3%vs. 8.1%, P=0.480);likewise, the mean aortic gradient post-procedure did not differ significantly(11.5±5.2 mmHg vs. 12.2±7.3 mmHg, 1 mmHg=0.133 kPa, P=0.580) between the groups. Devicesuccess rates were also similar (94.7% vs. 91.8%, P=0.680). In multivariable analysis, small BAV(P=0.027), the ratio of prosthesis diameter to annulus diameter (P=0.048), and mean aortic gradientby echo in the basement (P=0.021) were independent predictors of ***: The small BAV strategy is associated with a low rate of permanentpacemaker implantation after transcatheter self-expanding valve implantation in this single-centerobservational study.

关键词： Transcatheter aortic valve implantation Balloon aortic valvuloplasty Balloon size Permanent pacemaker implantation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Potato/Maize intercropping reduces infestation of potato tuber moth, Phthorimaea operculella(Zeller) by the enhancement of natural enemies

引用

Journal of Integrative Agriculture 2020年第2期19卷 394-405页

作者： ZHENG Ya-qiang ZHANG li-min CHEN Bin YAN Nai-sheng GUI Fu-rong ZAN Qing-an DU guang-zu HE Shu-qi li Zheng-yue GAO Yu-lin XIAO guan-li State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan Yunnan Agricultural UniversityKunming 650201P.R.China College of Agriculture&Biology Technology Yunnan Agricultural UniversityKunming 650201P.R.China State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijing 100193P.R.China

The potato tuber moth(PTM),Phthorimaea operculella(Zeller),is one of the most economically significant insect pests for potato in both field and storage *** evaluate the infestation,reduction of potato yield and the control efficacy for PTM,field tests were conducted in two seasons by intercropping of potato as the host plant with maize as a non-host plant of *** intercropping patterns were tested,which were 2 rows of potatoes with either 2,3,or 4 rows of maize(abbreviated 2 P:2 M,2 P:3 M,and 2 P:4 M),and the monocropped potato as the control,2 rows of potatoes,without maize,(abbreviated 2 P:0 M).Results showed that the population and infestation of PTM in the 2 P:3 M intercropping pattern was significantly lower than those in 2 P:2 M,2 P:4 M and the monocropping pattern of 2 P:0 M,due to the enhancement of natural *** mines and tunneling in potato leaves in 2 P:3 M intercropping were significantly lower than those in 2 P:2 M and 2 P:4 M *** population of parasitoids and the parasitism rate of PTM in intercropping pattern of 2 P:3 M were significantly higher than that in intercropping pattern of 2 P:2 M,2 P:4 M and monocropping pattern of 2 P:0 *** conclude that the potato intercropped with maize reduced the adult and larva populations,and reduced the damage from PTM by enhancing the number of parasitoids and the level of *** greatest population density of parasitoids and parasitism rate were in the intercropping pattern of 2 rows of potatoes with 3 rows of *** data indicate that the host/non-host intercropping patterns can be used as a biological control tactic against PTM by enhancing the density of natural enemies in the agro-ecosystems.

关键词： potato tuber moth Phthorimaea operculella(Zeller) intercrop biological control natural enemies parasitoids

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Relationship between Crustal 3D Density Structure and the Earthquakes in the Longmenshan Range and Adjacent Areas

引用

Acta Geologica Sinica(English Edition) 2009年第4期83卷 740-745页

作者： ZHANG Jisheng GAO Rui ZENG lingsen li Qiusheng guan Ye HE Rizheng WANG Haiyan LU Zhanwu Institute of Geology Chinese Academy of Geological SciencesEearthprobe and Geodynamics Open Laboratory of CAGS Beijing 100037 China

This paper presents the 3D density structure of crust in the Longmenshan range and adjacent areas, with constraints from seismic and density data. The density structure of crust shows that the immense boundary plane of density distribution in relation to the Longmeshan fault belt is extended downward to -80 km deep. This density boundary plane dips towards the northwest and crosses the Moho. With the proximity to the Longmenshan fault belt, it has a larger magnitude of undulation in the upper and middle crust levels. Density changes abruptly across Longmeshan fault belt. Seismic data show that most of the earthquakes in the Longmenshan area after the 2008 Ms8.0 Wenchuan Earthquake occurred within the upper to middle crust. These earthquakes are clearly distributed in the uplifted region of the basement. A few of them occurs in the transitional zone between the uplifted and subsided areas. But most of the earthquakes distributes in transitional zone from subsided to uplifted areas in the upper and middle crust where relatively large density changes occurr The 3D density structure of crust in the Longmenshan and adjacent areas can thus help us to understand the pattern of overthrusting from the standpoint of deep crust and where the earthquakes occurred.

关键词： Wenchuan earthquake Longmenshan fault zone gravity anomaly density structure of crust

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Strong Laws of Large Numbers for Fuzzy Set-Valued Random Variables in G_α Space

引用

Advances in Pure Mathematics 2016年第9期6卷 583-592页

作者： Lamei Shen li guan College of Applied Sciences Beijing University of Technology Beijing China

In this paper, we shall present the strong laws of large numbers for fuzzy set-valued random variables in the sense of d∞H . The results are based on the result of single-valued random variables obtained by Taylor [1... 详细信息

关键词： Laws of Large Numbers Fuzzy Set-Valued Random Variable Hausdorff Metric

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Diabetes onset at an earlier age and high HbA1c levels as risk factors of diabetic retinopathy

引用

International Journal of Ophthalmology(English edition) 2021年第2期14卷 269-276页

作者： Rui-Fang Feng Hai-Yang liu Ya-Lu liu Qing Xu Lei Qiao Chao-Ju Gong Yi-Peng Zhang Jie li li-Na guan Wei Fan Mei-li li Wen-Jin li Su-Yan li Department of Ophthalmology the Affiliated Xuzhou Municipal Hospital of Xuzhou Medical UniversityXuzhou First People’s HospitalXuzhou Eye Disease Prevention and Treatment InstituteXuzhou 221116Jiangsu ProvinceChina

AIM:To assess the effect of age at diabetes onset and uncontrollable high Hb A1 c levels on the development of diabetic retinopathy(DR)among Chinese type 2 diabetes mellitus(DM)***:This was a cross-sectional survey of diabetic patients in Subei district,*** covering physical measurements,fasting blood-glucose(FBG),glycosylated hemoglobin(Hb A1 c),blood lipid,urinary albumin/creatinine ratio(UACR),ocular fundus examination,and diabetes treatment records were *** independent sample t-test were used to analyze differences.A Logistic regression analysis was applied to study the independent risk factors of ***:A total of 1282 patients with type 2 DM were enrolled,and 191 cases had DR(14.9%).The age at diabetes onset,education level,alcohol consumption,Hb A1 c level,UACR level,and hypoglycemic drugs were independent influencing factors for *** older the onset of diabetes,the less likely to develop DR(OR:0.958,95%CI:0.942-0.975,P=0.000).Patients were then divided in terms of age at diabetes onset as follows:lin injection(52.5%)in patients with diabetes onsetlier age and uncontrollable high Hb A1 c level could be independent risk factors for DR.

关键词： diabetic retinopathy age diabetes mellitus risk factors HbA1c

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Short-term prognostic factors for hepatitis B virus-related acute-onchronic liver failure

引用

World Journal of Clinical Cases 2022年第23期10卷 8186-8195页

作者： Qiao-Xia Ye Jin-Fa Huang Zheng-Ju Xu Yan-Yan Yan Yan Yan li-guan liu Department of Infectious Diseases The 910^(th) Hospital of the Chinese People's Liberation Army Joint Logistic Support ForceQuanzhou 362000Fujian ProvinceChina

BACKGROUND Acute-on-chronic liver failure(ACLF)is the abrupt exacerbation of declined hepatic function in patients with chronic liver *** To explore the independent predictors of short-term prognosis in patients with hepatitis B virus(HBV)-related ACLF and to establish a predictive short-term prognosis model for HBV-related *** From January 2016 to December 2019,207 patients with HBV-related ACLF attending the 910^(th) Hospital of Chinese People's liberation Army were continuously included in this retrospective *** were stratified based on their survival status 3 mo after *** was collected regarding gender and age;coagulation function in terms of prothrombin time and international normalized ratio(INR);hematological profile in terms of neutrophil-tolymphocyte ratio(NLR)and platelet count(PLT);blood biochemistry in terms of alanine aminotransferase,aspartate aminotransferase,total bilirubin(Tbil),albumin,cholinesterase,blood urea nitrogen(BUN),creatinine,blood glucose,and sodium(Na);tumor markers including alpha-fetoprotein(AFP)and Golgi protein 73(GP73);virological indicators including HBV-DNA,HBsAg,HBeAg,Anti-HBe,and Anti-HBc;and complications including hepatic encephalopathy,hepatorenal syndrome,spontaneous peritonitis,gastrointestinal bleeding,and pulmonary *** There were 157 and 50 patients in the survival and death categories,*** analysis revealed significant differences in age,PLT,Tbil,BUN,NLR,HBsAg,AFP,GP73,INR,stage of liver failure,classification of liver failure,and incidence of complications(pulmonary infection,hepatic encephalopathy,spontaneous bacterial peritonitis,and upper gastrointestinal bleeding)between the two groups(Pliver failure(HR:5.056,95%CI:1.792-14.269,P=0.002),late stage of liver failure(HR:22.335,95%CI:8.544-58.388,P=0.000),pulmonary infection(HR:2.056,95%CI:1.14

关键词： Hepatitis B virus Acute-on-chronic liver failure Golgi protein 73 Short-term prognosis model

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hybrid Estimation of State and Input for linear Discrete Time-varying Systems： A Game Theory Approach

引用

自动化学报 2008年第6期34卷 665-669页

作者： YOU Fu-Qiang WANG Fu-li guan Shou-Ping Key Laboratory of Integrated Automation Process Industry Ministry of Education Northeastern University Shenyang 110004 P. R. China

为线性分离变化时间的系统的 H 混合评价问题在这份报纸被调查，在估计的信号是状态和输入的线性联合的地方。设计目的从骚乱要求最坏的精力获得到是的评价错误不到规定水平。混合评价问题的最佳的答案是僵绳点一二播放器零和微分游戏... 详细信息

为线性分离变化时间的系统的 H 混合评价问题在这份报纸被调查，在估计的信号是状态和输入的线性联合的地方。设计目的从骚乱要求最坏的精力获得到是的评价错误不到规定水平。混合评价问题的最佳的答案是僵绳点一二播放器零和微分游戏。根据微分比赛途径，为混合评价问题的必要、足够的可解决的条件以一个 Riccati 微分方程的答案被提供。而且，如果可解决的条件满足，一个可能的评估者被建议。评估者被印射矩阵的一个获得矩阵和产量描绘，在后者反映在未知输入和输出评价错误之间的内部关系的地方。最后，一个数字例子被提供说明建议途径。

关键词：博奕论线性离散系统时间变化系统智能化系统

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：