检索结果-南通市图书馆

Frontiers of Information Technology & Electronic Engineering 2016年第3期17卷 250-257页

作者： Jing li Xiao-run li li-jiao wang liao-ying ZHAO College of Electrical Engineering Zhejiang University Institute of Computer Application Technology Hangzhou Dianzi University

Endmember extraction is a key step in the hyperspectral image analysis process. The kernel new simplex growing algorithm （KNSGA）, recently developed as a nonlinear alternative to the simplex growing algorithm （SGA）, has proven a promising endmember extraction technique. However, KNSGA still suffers from two issues limiting its application. First, its random initialization leads to inconsistency in final results; second, excessive computation is caused by the iterations of a simplex volume calculation. To solve the first issue, the spatial pixel purity index （SPPI） method is used in this study to extract the first endrnember, eliminating the initialization dependence. A novel approach tackles the second issue by initially using a modified Cholesky fac- torization to decompose the volume matrix into triangular matrices, in order to avoid directly computing the determinant tauto- logically in the simplex volume formula. Theoretical analysis and experiments on both simulated and real spectral data demonstrate that the proposed algorithm significantly reduces computational complexity, and runs faster than the original algorithm.

关键词： Endmember extraction Modified Cholesky factorization Spatial pixel purity index (SPPI) New simplex growingalgorithm (NSGA) Kernel new simplex growing algorithm (KNSGA)

Beam-beam effects and mitigation in a future proton-proton collider

在线全文

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2022年第10期33卷 90-105页

作者： li-jiao wang Tanaji Sen Jing-Yu Tang lin-Hao Zhang Institute of High Energy Physics CASYuquan Road 19BBeijing 100049China University of Chinese Academy of Sciences CAS19A Yuquan RoadBeijing 100049China Spallation Neutron Source Science Center Dongguan 523803China Fermi National Accelerator Laboratory P.O.Box 500BataviaIL 60510USA

The beam-beam effects in a hadron collider with an unprecedented energy scale were *** effects are strongly related to the attainable luminosity of the ***-range interactions were identified as the major factor limiting the dynamic aperture,which is strongly dependent on the crossing angle,β*,and bunch *** mitigation methods of the beam-beam effects were addressed,with a focus on the compensation of long-range interactions by electric curren *** CEPC-SPPC project is a two-stage large circular collider,with a first-stage circular electron-positron collider(CEPC)and a second-stage super proton-proton collider(SPPC).The design of the SPPC aims to achieve a center-of-mass energy of 75 TeV and peak luminosity of approximately 1×10^(35) cm^(-2)s^(-1).We studied the beam-beam effects in the SPPC and tested the effectiveness of the mitigation *** found that with compensation using electric current wires,the dynamic aperture is at an acceptable ***,considering the significant emittance damping in this future proton-proton collider the beam-beam effects and compensation are more complicated and are studied using long-term *** was found that with a smaller emittance,the head-on interactions with a crossing angle become more prominent in reducing the beam stability,and combined head-on and long-range compensation is needed to improve the beam *** the reduction in population owing to burnoff was included,it was found that the coupling between the transverse and longitudinal planes at smaller emittance is the main driving source of the ***,crab cavities and emittance control are also necessary than just the compensation of the long-range interactions to improve the beam *** study serves as an example for studying the beam-beam effects in future proton-proton colliders.

关键词： Particle collider Beam-beam effects Luminosity Tune footprint Dynamic aperture

Luminosity optimization and leveling in the Super Proton-Proton Collider

在线全文

学校读者我要写书评

暂无评论

Radiation Detection Technology and Methods 2021年第2期5卷 245-254页

作者： li jiao wang Jing Yu Tang Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China

Purpose The design luminosity and the beam energy scale in the future Super Proton–Proton Collider(SPPC)are *** this article,different luminosity and leveling scenarios are studied to see if the luminosity design goal is *** The luminosity in a collider can be optimized by a group of machine parameters including beam emittance,number of bunches,bunch population,beta functions at the interaction point(IP),colliding mode(such as head-on or crossing,round or flat optics)and their changes during the colliding *** beam–beam effects,event pileup and machine turnaround time have direct impact on the *** measures or scenarios by taking the above factors are *** crab cavities are not available,the flat optics is studied to recover the luminosity lost due to a large crossing *** The luminosity patterns during the physics run and averaged luminosities are given for different luminosity *** can compare the performance potential and the technical difficulties among the *** difference between the round optics and flat optics in the case of no crab cavities is *** SPPC has a very high performance in the averaged *** luminosity optimization and leveling schemes are available to enhance the physics *** flat optics as a backup plan in the case of no crab cavities does help to improve the luminosity compared with the round optics.

关键词： Luminosity Colliding modes Event pileup Beam–beam effects Colliding optics

Experimental investigation on the radiation background inside body counters

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2022年第2期33卷 66-78页

作者： Yu wang Yuan-Yuan liu Bin Wu Xiang-Peng Meng Jian-Ping Cheng Ying wang li-jiao wang Yun-Shi Xiao Qin-Jian Cao Jian-Feng Zhang Fei Tuo Key Laboratory of Beam Technology of Ministry of Education College of Nuclear Science and TechnologyBeijing Normal UniversityBeijing 100875China Department of Nuclear Safety China Institute of Atomic EnergyBeijing 102413China Department of Health Physics China Institute for Radiation ProtectionTaiyuan 030006China National Institute for Radiological Protection Chinese Center for Disease Control and PreventionBeijing 100088China

In vivo measurement of radioactivity based on various body counters is arguably the leading measure used to determine the distribution and activity of radionuclides in human subjects,such as I-131 in the thyroid,Am-241 in the lungs,and Pb-210 in the *** the measurements,the radiation background is the key factor that determines the sensitivity of the ***,to facilitate in vivo measurements,a well-designed shielding room is required to create a low-background ***,because the compositions of the radiation background are quite complicated,the respective contributions from each source remain obscure,which places a considerable burden on seeking an optimized design of shielding rooms that strikes the optimum balance between the construction cost and background suppression *** this study,we conducted a systematic experimental investigation on the radiation background outside and inside four representative body counters with assorted designs using a variety of radiation detectors,including high-purity germanium detectors,CdZnTe detector,radon emanometer,and gamma-ray *** carefully controlling the experimental conditions and synergetic analysis of the measurement results,in conjunction with previous studies,we separated and determined the relative contributions induced by environmental radiation(4%),airborne radon and its daughters(2%),the normal radioactivity of human subjects arising from K-40(58%),cosmic rays(12%),and radioactivity in shielding materials and measuring instruments(24%).Furthermore,based on these results,we discuss practical guidelines to design a shielding room for body counters.

关键词： Body counter Radiation background Shielding room In vivo measurement

China＇s regional transport dominance： Density, proximity, and accessibility

在线全文

学校读者我要写书评

暂无评论

Journal of Geographical Sciences 2010年第2期20卷 295-309页

作者： JIN Fengjun wang Chengjin li Xiuwei wang jiao＇e Institute of Geographic Sciences and Natural Resources Research CAS Beijing 100101 China

Transport infrastructure plays an important role in shaping the configuration of spatial socio-economic structures and influences regional accessibility. This paper defines transport dominance from three aspects： quafity, quantity, and advantage, measured by density, proximity, and accessibility indices. County is the basic unit for analysis. The results reveal：（1） Transport dominance statistically follows a partial normal distribution. A very few counties, 1.4% of the total, have extremely high transport dominance which strongly supports the socio-economic development in these areas. In contrast, one eighth of all counties have poor transport dominance which impedes local socio-economic development to some extent. The remaining areas, about 70% of the counties, have median transport dominance. （2） Transport dominance is spatially unevenly distributed, with values decreasing gradually from the coastal area to the inland area. Areas in the first-highest level of transport dominance are mainly concentrated in the Yangtze River Delta, the Greater Beijing area, and the Pearl River Delta. Areas in the second-highest level are focused in Chengdu, Chongqing, and Wuhan metropolitan areas. Provincial capitals and a few other counties belong to the third-highest level.

关键词： transport dominance density proximity accessibility China

Successful Treatment with Rituximab in a Patient with Castleman＇s Disease Complicated by Systemic Lupus Erythematosus and Severe Autoimmune Thrombocytopenia

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2015年第18期128卷 2551-2552页

作者： Lu Zhang li jiao Shu-Jie wang Department of Hematology Peking Union Medical College Hospital Chinese Academy of Medical Sciences Beijing 100730 China

To the Editor： A 44-year-old man with no remarkable past medical history, was admitted with I-month history of fever and lymphadenopathy. He also had night sweats, malaise. arthralgia, urine volume reduction, abdominal distention, and weight loss. Physical exainination revealed swollen lymph nodes in the neck, axillary fossae and inguinal grooves, palpable liver and spleen, shifting dullness and edema.

关键词：发热肝关节痛红斑狼疮系统性颈巨淋巴结增生脾紫癜血小板减少性特发性

Anti-CD69 monoclonal antibody treatment inhibits airway inflammation in a mouse model of asthma

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2015年第7期16卷 622-631页

作者： Hui-ying wang Yu DAI jiao-li wang Xu-yan YANG Xin-guo JIANG Department of Allergy the Second Affiliated Hospital School of Medicine Zhejiang University Department of Clinical Laboratory the Second Affiliated Hospital School of Medicine Zhejiang University Department of Respiratory Medicine Hangzhou First People's Hospital Department of Rheumatology and Clinical Immunology the Second Affiliated Hospital School of MedicineZhejiang University Department of Medicine VA Palo Alto Health Care System/Stanford University School of Medicine

Objective： Airway inflammation and airway hyper-responsiveness（AHR） are principle pathological manifestations of asthma. Cluster of differentiation 69（CD69） is a well-known co-stimulatory factor associated with the activation, proliferation as well as apoptosis of immune cells. This study aims to examine the effect of anti-CD69 monoclonal antibody（m Ab） on the pathophysiology of a mouse model of asthma. Methods： A murine model of ovalbumin（OVA）-induced allergic airway inflammation was used in this study. Briefly, mice were injected with 20 μg chicken OVA intraperitoneally on Days 0 and 14, followed by aerosol provocation with 1%（0.01 g/ml） OVA on Days 24, 25, and 26. Anti-CD69 m Ab or isotype Ig G was injected intraperitoneally after OVA challenge; dexamethasone（DXM） was administrated either before or after OVA challenge. AHR, mucus production, and eosinophil infiltration in the peribronchial area were examined. The levels of granulocyte-macrophage colony-stimulating factor（GM-CSF） and interleukin-5（IL-5） in bronchoalveolar lavage fluid（BALF） were also assayed as indices of airway inflammation on Day 28 following OVA injection. Results： Pretreatment with DXM together with anti-CD69 m Ab treatment after OVA provocation completely inhibited AHR, eosinophil infiltration and mucus overproduction, and significantly reduced BALF IL-5. However, treatment with DXM alone after OVA challenge only partially inhibited AHR, eosinophil infiltration and mucus overproduction, and did not diminish BALF IL-5. Treatment with either DXM or anti-CD69 m Ab did not alter the concentration of BALF GM-CSF. Conclusions： Anti-CD69 m Ab treatment inhibits established airway inflammation as effectively as DXM pretreatment. This study provides a potential alternative therapeutic opportunity for the clinical management of asthma and its exacerbation.

关键词： Cluster of differentiation 69(CD69) Eosinophil Interleukin-5(IL-5) Asthma

Variations in Reproductive Hormones during Estrus Cycle in Local Beef Cattle from Jilin of China

在线全文

学校读者我要写书评

暂无评论

Animal Husbandry and Feed Science 2010年第4期2卷 14-17页

作者： li Cheng-jiao wang Hong-juan li Chun-jin ZHOU Xu College of Animal Science and Veterinary Medicine Jilin University Changchun 130062 China

[ Objective] To provide a theoretical basis for improving reproductive efficiency of domestic beef cattle in Jilin of China. [ Method] China Red Steppe cattle, Yanbian yellow cattle and Simmental cattle in Jilin Province were used for detection. The levels of progesterone （P4）, estradiol （ E2 ）, follicle-stimulating hormone （FSH） and luteinizing hormone （LH） in serum and urine during estrus cycle were determined. [ Result] The levels of P4 and E2 were significantly different between pregnant cattle and non-pregnant cattle on Day 21 post estrus （ P 〈 0.01 ）. The level of LH on estrus day was significantly different from that on the other days of estrus cycle （ P 〈 0.05）. [ Conclusion] It is feasible to detect P4 level for diagnosis of estrus and eady pregnancy in beef cattle.

关键词： Reproductive hormones Estrus cycle Beef cattle

Allele-specific real-time PCR testing for minor HIV-1 drug resistance mutations： assay preparation and application to reveal dynamic of mutations in vivo

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2010年第23期123卷 3389-3395页

作者： GUO Dong-xing li Han-ping li lin ZHUANG Dao-min jiao li-yan wang Zheng BAO Zuo-yi liU Si-yang liU Yong-jian li Jing-yun State Key Laboratory of Pathogen and Biosecurity Beijing Institute of Microbiology and Epidemiology Beijing 100071China

Background It is very important for the clinical management to test for minor HIV-1 resistance mutations accurately and sensitively. The conventional genotypic assays of HIV drug resistance detection based on sequencing can only discriminate the mutations which present in more than 20%-30%. The aim of this study was to evaluate allele-specific real-time PCR （ASPCR） to detect the resistance-related mutations located at positions 103, 184 and *** We developed the allele-specific PCR assay, using the most common drug resistance mutations in Chinese AIDS patients, K103N, M184V/I, T215F/Y as a model system. The standards were constructed by cloning the wild-type and mutant DNA fragments into the T-vector. We designed specific primers to discriminate mutant templates in the real-time PCR using SYBR green as a fluorescence reporter. And then we evaluated the ASPCR assay and tested 140clinical samples using this *** The sensitivities of ASPCR assay were 0.04% for K103N, 0.30% for M1841, 0.40% for M184V, 0.03% for T215F and 0.02% for T215Y. The intra-assay and inter-assay coefficients of variation were less than 0.42. One hundred and forty plasma samples were tested by ASPCR and dynamic resistance curves of ten patients were *** Drug resistance emerged half a year after the start of antiretroviral therapy. The mutation of T215Yemerged 1 to 1.5 years after starting treatment and then increased rapidly. The ASPCR assay we developed was a sensitive, accurate and rapid method to detect the minor HIV-1 variants and it can provide earlier and more drug-resistance information for HIV research and AIDS antiretroviral therapy.

关键词： allele-specific real-time PCR minor populations drug resistance human immunodeficiency virus

Improving prediction of vapor-liquid equilibrium with modified HVOS-PR-UNIFAC model by revision of group interaction parameters

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Chongqing University 2007年第2期6卷 93-99页

作者： XUE Rong-shu li Yan-jiao wang Xiao-qing TAN Shi-yu WEI Shun-an College of Chemistry ＆ Chemical Engineering Chongqing University Chongqing 400044P.R.China

Quantitative description of vapor-liquid equilibrium is very useful for designing separation processes. In this study, we combined the Peng-Robinson equation and the Huron-Vidal-Orbey-Sandler mixing rule into a modified UNIFAC model for the improvement of predicting vapor-liquid equilibria. The predictions of vapor-liquid equilibria for 62 systems including alcohol- alkane, alcohol-benzene, and amine-water systems demonstrate that the revised parameters remarkably improve the prediction accuracy for many systems. Especially for amine-water system, the mean deviation of components decreases from 0.094 to 0.021, and the mean deviation of pressure from 22.45% to 4.41%.

关键词： group interaction parameter UNIFAC mode vapor-liquid equilibrium