检索结果-南通市图书馆

Functions of Survivin Gene and its Relationship between Expression and Prognosis in Patients with Nasopharyngeal Carcinoma

在线全文

学校读者我要写书评

暂无评论

Functions of Survivin Gene and its Relationship between Expr...

单侧内直肌截除术治疗儿童残余性和复发性外斜视的疗效观察

第七届生命科学联合学术大会

作者： Jun-Hong Cai Sheng-Miao Fu Zhi-hua Tu li-Qun Deng Zu.liang Xin-Ping Chen Xuan-Ju Gong li-hua wang College of Laboratory Medicine Chongqing Medical University Department of Medicine Laboratory Hainan Provincial People's HospitalHainan Provincial Key Laboratory for Cell and Molecular Genetic Translational Medicine

This study aimed to investigate the relationship between prognosis and the expression products of apoptotic inhibitor gene,survivin protein and m RNA in patients with nasopharyngeal carcinoma,and further the functions of surviving gene in nasopharyngeal carcinoma cell line *** and hybridization in situ technique were used in detecting the survivin protein and m RNA in 44 nasopharyngeal carcinoma specimens,30 chronic nasopharyngitis specimens as the *** gene in CNE2 cell line was interfered by sh RNA(short hairpin RNA).The positive ratios of expression for survivin protein and m RNA in nasopharyngeal carcinoma were 79.5%and 75.0%respectively,higher than those of control group obviously(pliferation of CNE2 cell line is inhibited distinctly by the specifical sh RNA that could interfere the survivin *** over expression of survivin gene plays an important role in onset and development of nasopharyngeal carcinoma,and it will be helpful for prognosis appraisal of nasopharyngeal carcinoma.

关键词： Survivin gene-nasopharyngeal carcinoma – prognosis

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

国际眼科杂志 2018年第1期18卷 195-197页

作者：王涛杨相泽王利华中国山东省威海市立医院眼科 264200 山东大学附属省立医院眼科中国山东省济南市250021

目的:探讨单侧内直肌截除术治疗儿童残余性和复发性外斜视的有效性及安全性,评价其在不同外斜视类型及不同初次手术方式应用的差异性。方法:回顾性病例系列研究。收集2009-01/2013-02在山东大学附属山东省立医院行单侧内直肌截除术治疗... 详细信息

目的:探讨单侧内直肌截除术治疗儿童残余性和复发性外斜视的有效性及安全性,评价其在不同外斜视类型及不同初次手术方式应用的差异性。方法:回顾性病例系列研究。收集2009-01/2013-02在山东大学附属山东省立医院行单侧内直肌截除术治疗的残余性和复发性外斜视连续性病例48例48眼,观察术后第1d,6wk以及末次随访(术后6~32mo)时患儿眼位、眼位非共同性、融合功能及立体视锐度情况。结果:术后第1d手术正位率为83%(40/48),欠矫率为4%(2/48),过矫率为13%(6/48);术后第6wk手术正位率为81%(39/48),欠矫率为13%(6/48),过矫率为6%(3/48);末次随访时正位率为75%(36/48),欠矫率为25%(12/48),无1例过矫。不同初次手术方式和不同外斜视类型患儿末次随访时手术正位率的差异均无统计学意义(P=0.168、0.50)。术后所有病例均未出现眼球运动非共同性和眼球外转受限。结论:单侧内直肌截除术是治疗儿童残余性和复发性外斜视的安全有效术式。

关键词：单侧内直肌截除术外斜视复发性手术

Salvianolic Acid B induces GRP7/8 in human endothelial cells:another protective mechanism against oxidative stress-induced cellular damage

在线全文

学校读者我要写书评

暂无评论

Salvianolic Acid B induces GRP7/8 in human endothelial cells...

磺化聚酰亚胺酸碱复合膜的制备及其在全钒液流电池中的应用

第六届海峡两岸心血管科学研讨会

作者： WU Hong-li li Yu-hua wang Rui li Ying-bo li Xue-Jun Department of Pharmacology,School of Basic Medical Sciences,Peking University

Salvia miltiorrhiza (SM),a traditional Chinese herb,is often used in treatment of cardiovascular diseases to resolve *** acid B (Sal B) is considered to be the major pharmacological active component and most active anti-oxidant of *** the present investigation,we studied the protective activity of Sal B on HO induced

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

高分子学报 2015年第4期25卷 418-426页

作者：张斌刘帅王丽华韩旭彤天津工业大学材料科学与工程学院天津300387 中国科学院化学研究所北京100190

采用高温一步法合成了一系列不同磺化度的三元共聚磺化聚酰亚胺(SPI),通过控制磺化二胺与非磺化二胺的摩尔比来调节磺化度.选取碱性聚合物聚乙烯吡咯烷酮(PVP)与SPI按质量比1∶9进行共混,制成SPI/PVP酸碱复合膜.对复合膜的吸水率、离子... 详细信息

采用高温一步法合成了一系列不同磺化度的三元共聚磺化聚酰亚胺(SPI),通过控制磺化二胺与非磺化二胺的摩尔比来调节磺化度.选取碱性聚合物聚乙烯吡咯烷酮(PVP)与SPI按质量比1∶9进行共混,制成SPI/PVP酸碱复合膜.对复合膜的吸水率、离子交换容量、钒离子渗透率以及电池性能进行了测试.结果表明,随着磺化度的升高,复合膜的吸水率、离子交换容量、质子电导率升高以及钒离子渗透率升高.复合膜的隔膜选择性比Nafion117的选择性好,其中SPI/PVP-3的选择性是Nafion117的10倍.电池性能测试表明,随磺化度的升高,复合膜能量效率升高.其中SPI/PVP-3膜较Nafion117膜具有较高的库伦效率和能量效率,通过循环测试SPI/PVP-3膜性能稳定,充放电理想.

关键词：磺化聚酰亚胺酸碱复合膜全钒氧化还原液流电池钒离子渗透率电池效率

在线全文

学校读者我要写书评

暂无评论

梅岭国家森林公园声景观的游客调查评价

林业科学 2018年第6期54卷 9-15页

作者：李华王雨晴陈飞平江西农业大学职业师范学院南昌330045 江西农业大学园林与艺术学院南昌330045

【目的】发掘森林声景设计手法来指导城市公共空间的声景设计。【方法】以梅岭国家森林公园声音景观为研究对象,通过实地勘测和问卷调查方式对单个声源和整体声景观进行评价。单个声源评价方法为评价者对调查问卷提供的26种声音以即时... 详细信息

【目的】发掘森林声景设计手法来指导城市公共空间的声景设计。【方法】以梅岭国家森林公园声音景观为研究对象,通过实地勘测和问卷调查方式对单个声源和整体声景观进行评价。单个声源评价方法为评价者对调查问卷提供的26种声音以即时的身临其境之感进行主观喜好度评价,评价等级分为5级,以统计平均值方式进行喜好程度的判定;四季声景观总体评价以响度、协调度、舒适度和满意度为评价指标,首先对各个指标在四季中的结果进行统计,以计算平均值法比较四季中各个指标的变化趋势,了解游客在四季中对整体声景的主观评价。【结果】游客在不同季节对不同声源的喜好度有差别,各声景类型受喜爱程度表现为自然声>历史文化声>人工声>机械声;整体声景的评价表明,游客对梅岭森林公园声景观现状满意度较高;四季中,响度、协调度、舒适度都会影响整体满意度的评价,其中协调度、舒适度越高,总体满意度越高;春夏季响度越高,满意度评价越低,而秋冬季满意度与响度相关性不大。【结论】在后期森林景观规划和声景观设计与营造中,应综合考虑声音响度对人的影响,增加鸟鸣声、流水声等人们喜爱的声源,隔离或规避鸣笛声、施工声等人们反感的声源,从而提高整体声景观的满意度。

关键词：森林公园声景观主观评价声源

在线全文

学校读者我要写书评

暂无评论

宁东侏罗系煤层顶板粗粒含水砂岩特性研究

煤炭学报 2017年第1期42卷 183-188页

作者：姚强岭陈田李学华王傲中国矿业大学矿业工程学院江苏徐州221116 中国矿业大学深部煤炭资源开采教育部重点实验室江苏徐州221116

相似模拟实验研究一直是保水开采的主要实验手段之一,其中相似材料与岩石之间力学参数的相似度尤为关键。宁东煤田属于我国典型的生态脆弱矿区,该区域主采煤层为侏罗系煤层,其顶底板广泛分布着成岩程度低且富含黏土矿物的一类特殊砂岩,... 详细信息

相似模拟实验研究一直是保水开采的主要实验手段之一,其中相似材料与岩石之间力学参数的相似度尤为关键。宁东煤田属于我国典型的生态脆弱矿区,该区域主采煤层为侏罗系煤层,其顶底板广泛分布着成岩程度低且富含黏土矿物的一类特殊砂岩,该层砂岩在采动、吸水-失水动态循环作用下呈现软岩力学特征。选取其中的一类含水砂岩为研究对象,通过分析该含水砂岩岩石成分和结构特征确定其为粗粒泥质长石砂岩,并分析认为其形成于快速堆积的沉积环境;利用X衍射仪定量分析其矿物组分,发现该含水砂岩主要由黏土矿物、石英和长石组成,其中黏土矿物富含蒙脱石、伊蒙混层及绿泥石等吸水易膨胀组分;利用MTS伺服控制试验机研究了该类砂岩三轴抗压强度及渗透特性,发现其具有明显的塑性破坏特征;且饱水含水砂岩渗透率有突变点存在,突变点后渗透率大致恒定直至试件破坏时渗透率增至最大值;进一步研究了含水率对该含水砂岩单轴压缩变形特征的影响规律,发现含水砂岩单轴抗压强度、弹性模量与含水率负线性相关。

关键词：生态脆弱矿区含水砂岩相似模拟保水开采

Rationale,design,and baseline characteristics of Chinese registry in early detection and risk stratification of coronary plaques(C-STRAT)study

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2021年第7期134卷 870-872页

作者： Jun-Jie Yang Dong-Kai Shan Lei Xu Jun-Fu liang Zhao-Qian wang Mei Zhang Min li Wen-Jie Yang Jian-Rong Xu Yong-Gao Zhang li-Ming Xia li-hua wang Hong-Jie Hu Zhi-Gang Yang Tao li Qi Tian Xu-Dong Lyu Yun-Dai Chen Department of Cardiology the First Medical CenterChinese PLA General HospitalBeijing 100853China Department of Radiology Beijing Anzhen HospitalCapital Medical UniversityBeijing 100029China Beijing huairou Hospital Beijing 101400China The First Affiliated Hospital of Dalian Medical University DalianLiaoning 116011China Department of Cardiology Qilu Hospital of Shandong UniversityJinanShandong 250012China 960 Hospital of PLA JinanShandong 250031China Department of Radiology Shanghai Jiao Tong University Medical School Affiliated Ruijin HospitalShanghai 200025China Department of Radiology Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200127China The First Affiliated Hospital of Zhengzhou University ZhengzhouHenan 450052China Department of Radiology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430030China The Second Affiliated Hospital of Zhejiang University College of Medicine HangzhouZhejiang 310009China Sir Run Run Shaw Hospital School of MedicineZhejiang UniversityHangzhouZhejiang 310016China Department of Radiology West China HospitalSichuan UniversityChengduSichuan 610041China Radiology Department the First Medical CenterChinese PLA General HospitalBeijing 100853China College of Biomedical Engineering and Instrumental Science Zhejiang UniversityHangzhouZhejiang 310027China.

To the Editor:Coronary computed tomographic angiography(CCTA)has been considered as one of the most important noninvasive imaging modalities in diagnosing coronary artery disease(CAD).[1]Modern scanner of CCTA can provide precise coronary atherosclerotic plaque information,showing improved diagnostic accuracy and sensitivity for identifying obstructive CAD with a preferable temporal and spatial *** studies have demonstrated the prognosis value of CCTA for the prediction of future adverse CAD events.

关键词： coronary Rational scanner

资本下乡与隐蔽的水权流动——以广西大规模甘蔗种植为例

在线全文

学校读者我要写书评

暂无评论

开放时代 2018年第4期 185-196页

作者：李华汪淳玉叶敬忠太原理工大学政法学院中国农业大学人文与发展学院

针对资本下乡现象,学界侧重于考察土地流转所带来的人地关系变迁,对土地流转背后较具隐蔽性的人水关系变迁关注不足。农业资本在土地流转过程中通常更为青睐有水源保障的土地,其作为新的用水主体进而也重组了村庄既有的水分配格局,促使... 详细信息

针对资本下乡现象,学界侧重于考察土地流转所带来的人地关系变迁,对土地流转背后较具隐蔽性的人水关系变迁关注不足。农业资本在土地流转过程中通常更为青睐有水源保障的土地,其作为新的用水主体进而也重组了村庄既有的水分配格局,促使水资源的实际控制权发生流动。本文以广西大规模甘蔗种植为例,揭示了农业公司在甘蔗种植过程中的用水策略和逻辑,认为农业公司的出现挤压了当地农户的水资源获取空间,并以威胁当地生态环境安全、村民利益及社区发展为代价满足自身盈利和增殖的需求。在资本下乡热的背景下,普通农户的水权应该得到尊重和保护。此外,农业扶持政策和补贴分配不能仅以经济效益和规模效应最大化为中心,资本主导的农业经营模式对水资源的需求和使用方式及其对生态环境的影响应该纳入政策设计和决策过程中。

关键词：资本下乡土地流转水权流动

Validation of aspartate aminotransferase to platelet ratiofor diagnosis of liver fibrosis and prediction of postoperativeprognosis in infants with biliary atresia

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2015年第19期21卷 5893-5900页

作者： li-Yuan Yang, Jie Fu, Xiao-Fang Peng, Shu-Yin Pang, Kan-Kan Gao, Zheng-Rong Chen, li-Juan He, Zhe Wen, Hui wang, Le li, Feng-hua wang, Jia-Kang Yu, Yi Xu, Si-Tang Gong, Hui-Min Xia, and Hai-Ying liu li-Yuan Yang Xiao-Fang Peng Shu-Yin Pang Kan-Kan Gao Hai-Ying Liu Clinical Laboratory Guangzhou Medical University Affiliated Guangzhou Women and Children&#x02019 s Medical Center Guangzhou 510120 Guangdong Province China Jie Fu Birth Cohort Study Guangzhou Medical University Affiliated Guangzhou Women and Children&#x02019 s Medical Center Guangzhou 510623 Guangdong Province China Zheng-Rong Chen Li-Juan He Feng-Hua Wang Department of Pathology Guangzhou Medical University Affiliated Guangzhou Women and Children&#x02019 s Medical Center Guangzhou 510623 Guangdong Province China Zhe Wen Hui Wang Le Li Jia-Kang Yu Hui-Min Xia Department of Neonatal Surgery Guangzhou Medical University Affiliated Guangzhou Women and Children&#x02019 s Medical Center Guangzhou 510623 Guangdong Province China Yi Xu Si-Tang Gong Department of Infectious Diseases Guangzhou Medical University Affiliated Guangzhou Women and Children&#x02019 s Medical Center Guangzhou 510120 Guangdong Province China

Validation of aspartate aminotransferase to platelet ratiofor diagnosis of liver fibrosis and prediction of postoperativeprognosis in infants with biliary atresia pathological Metavir fibrosis score of the liver wedgespecimens of 91 BA infants. The prognostic value ofpreoperative APRI for jaundice persistence, liver injury,and occurrence of cholangitis within 6 mo after KP wasstudied based on the follow-up data of 48 BA ***： APRI was significantly correlated withMetavir scores （rs = 0.433; P 〈 0.05）. The mean APRIvalue was 0.76 in no/mild fibrosis group （Metavir scoreF0-F1）, 1.29 in significant fibrosis group （F2-F3）, and2.51 in cirrhosis group （F4）（P 〈 0.001）. The areaunder the ROC curve （AUC） of APRI for diagnosingsignificant fibrosis and cirrhosis was 0.75 （P 〈 0.001）and 0.81 （P = 0.001）, respectively. The APRI cut-offof 0.95 was 60.6% sensitive and 76.0% specific forsignificant fibrosis diagnosis, and a threshold of 1.66was 70.6% sensitive and 82.7% specific for *** preoperative APRI in infants who maintainedjaundice around 6 mo after KP was higher than thatin those who did not （1.86 ± 2.13 vs 0.87 ± 0.48, P 〈0.05）. The AUC of APRI for prediction of postoperativejaundice occurrence was 0.67. A cut-off value of0.60 showed a sensitivity of 66.7% and a specificityof 83.3% for the prediction of jaundice *** APRI had no significant association withlater liver injury or occurrence of ***： Our study demonstrated that APRIcould diagnose significant liver fibrosis, especiallycirrhosis in BA infants, and the elevated preoperativeAPRI predicts jaundice persistence after KP.

关键词： Aspartate aminotransferase to platelet ratioindex Biliary atresia Cirrhosis liver fibrosis Prognosis