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Trial characteristics and treatment effect estimates in randomized controlled trials of Chinese herbal medicine: A meta-epidemiological study

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Journal of Integrative Medicine 2024年第3期22卷 223-234页

作者： Betty H.Wang ya-li lin Yin-yan Gao Jin-lu Song Lang Qin ling-qi li Wen-qi liu Claire C.W.Zhong Mary Y.Jiang Chen Mao Xiao-bo yang Vincent C.H.Chung Irene X.Y.Wu Jockey Club School of Public Health and Primary Care the Chinese University of Hong KongHong Kong 999077China Xiangya School of Public Health Central South UniversityChangsha 410006Hunan ProvinceChina School of Chinese Medicine the Chinese University of Hong KongHong Kong 999077China School of Public Health Southern Medical UniversityGuangzhou 510080Guangdong ProvinceChina State Key Laboratory of Dampness Syndrome of Chinese Medicine the Second Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou 510120Guangdong ProvinceChina Chinese Medicine Syndrome Research Team the Second Affiliated HospitalGuangzhou University of Chinese MedicineGuangzhou 510120Guangdong ProvinceChina Guangdong Provincial Key Laboratory of Clinical Research on Traditional Chinese Medicine Syndrome Guangzhou 510120Guangdong ProvinceChina Hunan Provincial Key Laboratory of Clinical Epidemiology Central South UniversityChangsha 410006Hunan ProvinceChina

Background:Previously published meta-epidemiological studies focused on Western medicine have identified some trial characteristics that impact the treatment effect of randomized controlled trials(RCTs).Nevertheless,it remains unclear if similar associations exist in RCTs on Chinese herbal medicine(CHM).Further,Chinese medicine-related characteristics have not been explored ***:To investigate trial characteristics related to treatment effect estimates on CHM *** strategy:This meta-epidemiological study searched 5 databases for systematic reviews on CHM treatment published between January 2011 and July *** criteria:An eligible systematic review should only include RCTs of CHM and conduct at least one *** extraction and analysis:Two reviewers independently conducted data extraction on general characteristics of systematic reviews,meta-analyses and included *** also assessed the risk of bias of RCTs using the Cochrane risk of bias tool.A two-step approach was used for data *** ratio of odds ratios(ROR) and difference in standardized mean differences (dSMD) with 95%confidence interval (CI) were applied to present the difference in effect estimates for binary and continuous outcomes,***:Ninety-one systematic reviews,comprising 1338 RCTs were *** binary outcomes,RCTs incorporated with syndrome differentiation (ROR:1.23;95%CI:[1.07,1.39]),adopting Chinese medicine formula (ROR:1.19;95%CI:[1.03,1.34]),with low risk of bias on incomplete outcome data (ROR:1.29;95%CI:[1.06,1.52]) and selective outcome reporting (ROR:1.12;95%CI:[1.01,1.24]),as well as a trial size≥100 (ROR:1.23;95%CI:[1.04,1.42]) preferred to show larger effect *** for continuous outcomes,RCTs with Chinese medicine diagnostic criteria (dSMD:0.23;95%CI:[0.06,0.41]),judged as high/unclear risk of bias on allocation concealment (dSMD:-0.70;95%CI:[-0.99,-0.42]),with low risk of bias on incomplete outcome data (dSMD:0.30

关键词： Chinese herbal medicine Randomized controlled trial Risk of bias Meta-epidemiological study Effect estimates

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基于木质异型材的两自由度工作台研究

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林业机械与木工设备 2024年第6期52卷 49-54页

作者：李滨栗雅琳东北林业大学机电工程学院黑龙江哈尔滨150040

设计了一种两自由度可旋转工作台,用于辅助普通三轴数控机床对木质异型材进行复杂曲面加工。该工作台可通过两台电机控制工作台同时或分别进行X轴和Y轴方向上的旋转,左侧电机驱动蜗轮蜗杆传动实现工作台X轴向旋转,右侧电机驱动齿轮副传... 详细信息

设计了一种两自由度可旋转工作台,用于辅助普通三轴数控机床对木质异型材进行复杂曲面加工。该工作台可通过两台电机控制工作台同时或分别进行X轴和Y轴方向上的旋转,左侧电机驱动蜗轮蜗杆传动实现工作台X轴向旋转,右侧电机驱动齿轮副传动实现工作台Y轴向旋转,通过互相配合实现多平面、多角度加工。通过对工作台关键支撑结构进行静力学分析与模态分析,确定工作台整体支撑结构合理性,为两自由度工作台结构设计提供参考。

关键词：两自由度工作台木质异型材结构设计 ANSYS分析

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基于MCFT的腐蚀RC矮墩柱数值模拟方法

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工程力学 2024年第8期41卷 131-140页

作者：李亚林郑山锁尚志刚段培亮陈嘉晨西安建筑科技大学土木工程学院西安710055 西安建筑科技大学结构工程与抗震教育部重点实验室西安710055

采用电化学氯腐蚀的方法对5根剪跨比为2的RC矮墩柱进行室内加速腐蚀试验,并对其进行拟静力加载试验。根据试验结果分析了腐蚀损伤和轴压比对RC柱破坏过程、承载能力、变形能力和耗能能力的影响。通过理论推导,建立了基于MCFT(修正压力... 详细信息

采用电化学氯腐蚀的方法对5根剪跨比为2的RC矮墩柱进行室内加速腐蚀试验,并对其进行拟静力加载试验。根据试验结果分析了腐蚀损伤和轴压比对RC柱破坏过程、承载能力、变形能力和耗能能力的影响。通过理论推导,建立了基于MCFT(修正压力场理论)的考虑腐蚀损伤的钢筋混凝土剪切行为本构模型,进而提出了考虑弯-剪-滑移耦合效应的数值模拟方法。对比模拟结果和试验结果可知:采用该模拟方法得到的各柱试件的滞回曲线与实际滞回曲线符合较好,骨架曲线特征点及累积耗能值误差较小,表明该研究提出的考虑腐蚀的剪切行为本构及数值模拟方法可以较为准确地反映腐蚀RC矮墩柱的抗震性能,该研究成果可为腐蚀损伤在役RC墩柱的抗震性能评估奠定基础。

关键词： RC矮墩柱腐蚀损伤剪切本构模型数值模拟纤维模型

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MOTION OF TRACER PARTICLES IN A CENTRIFUGAL PUMP AND ITS TRACKING CHARACTERISTICS

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Journal of Hydrodynamics 2012年第5期24卷 785-793页

作者： li ya-lin YUAN Shou-qi TANG Yue YUAN Jian-ping Research Center of Fluid Machinery Engineering and Technology Jiangsu University Zhenjiang 212013 China

The Basset-Boussinesq-Oseen （BBO） equation can be used for most flows to trace the motion of a particle, but in a centrifugal pump, among the forces that act on the particles, one should also include those due to the impeller rotation, as additional effects. This paper firstly reviews various approximations of the BBO equation for the motion of dispersion particles in a viscous fluid. Then based on the motion equation for particles in low Reynolds number centrifugal pumps, a formula for calculating the tracking characteristics of tracer particles is deduced through the Fourier integral transformation. After that the deviations of the particle motion from the fluid motion, as predicted by the various approximations, are discussed and compared. At last, with an emphasis on the Particle Image Velocimetry （PIV） results, the tracking characteristics of particles are estimated. Also, advantages and disadvantages of different tracer particles are discussed and suitable tracer particles for application in PIV studies for flow fields in centrifugal pumps are suggested.

关键词： tracer particles equations of motion tracking characteristics centrifugal pump Particle Image Velocimetry (PIV)

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基于地理信息系统的矿山环境恢复与治理规划有效策略

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世界有色金属 2024年第12期 140-142页

作者：张宏达李雅琳中国建筑材料工业地质勘查中心甘肃总队甘肃天水741000

在现代采矿行业的不断发展中,矿山环境的恢复及其治理也成为了一项需要重点关注的内容。基于此,本文便以某矿山环境评价及其恢复治理项目为例,对基于地理信息系统的矿山环境恢复及其治理规划策略进行分析。包括本次所研究的项目概况,地... 详细信息

在现代采矿行业的不断发展中,矿山环境的恢复及其治理也成为了一项需要重点关注的内容。基于此,本文便以某矿山环境评价及其恢复治理项目为例,对基于地理信息系统的矿山环境恢复及其治理规划策略进行分析。包括本次所研究的项目概况,地理信息系统介绍,基于地理信息系统的矿山环境恢复治理问题评价,以及基于地理信息系统的矿山环境恢复及其治理规划策略分析。希望通过本次分析,可以为地理信息系统的合理应用提供一定参考,以此来对矿山环境恢复及其治理做出有效规划。

关键词：地理信息系统矿山环境环境评价环境恢复和治理

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Expression and functional characterization of platelet-derived growth factor receptor-like gene

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World Journal of Gastroenterology 2010年第12期16卷 1465-1472页

作者： Guo, Feng-Jie Zhang, Wei-Jia li, ya-lin liu, yan li, Yue-Hui Huang, Jian Wang, Jia-Jia Xie, Ping-li li, Guan-Cheng Cent S Univ Xiangya Sch Med Canc Res Inst Changsha 410078 Hunan Peoples R China

AIM:To investigate the role of platelet-derived growth factor receptor-like gene(PDGFRL)in the anti-cancer therapy for colorectal cancers(CRC).METHODS:PDGFRL mRNA and protein levels were measured by reverse transcription-polymerase chain reaction(RT-PCR)and immunohistochemistry in CRC and colorectal normal *** prokaryotic expression vector was carried out in Escherichia coli(***),and purified by immobilized metal affinity *** effect of PDGFRL protein on CRC HCT-116 cells was detected by 3-(4,5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide(MTT),clone counting,cell cycle,and wound healing ***:Both RT-PCR and immunohistochemistry showed that the expression of PDGFRL in colorectal normal tissues was higher than in cancer *** pET22b-PDGFRL prokaryotic expression vector was successfully expressed in ***,and the target protein was expressed in the form of inclusion *** purification and refolding,recombinant human PDGFRL(rhPDGFRL)could efficiently inhibit the proliferation and invasion of CRC HCT-116 cells detected by MTT,clone counting and wound healing ***,rhPDGFRL arrested HCT-116 cell cycling at the G0/G1 ***:PDGFRL is a potential gene for application in the anti-cancer therapy for CRC.

关键词： Platelet-derived growth factor receptorlike Colorectal cancer Prokaryotic expression Reverse transcription-polymerase chain reaction Immunohistochemistry

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脑脊液乳酸联合血肌钙蛋白I、N末端脑钠肽前体水平对动脉瘤性蛛网膜下腔出血预后有预测价值

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内科急危重症杂志 2024年第1期30卷 51-54,74页

作者：康寿磊李金秀荣风燕李亚霖王文涛山东第一医科大学附属聊城第二人民医院重症医学科山东临清252600

目的:探讨脑脊液中乳酸联合血肌钙蛋白I (cTnI)、N末端脑钠肽前体(NT-proBNP)水平对动脉瘤性蛛网膜下腔出血(aSAH)患者预后的评估价值。方法:选择80例aSAH患者,检测并记录患者发病后第1、3、7天脑脊液乳酸浓度,收集患者血常规、肝肾功... 详细信息

目的:探讨脑脊液中乳酸联合血肌钙蛋白I (cTnI)、N末端脑钠肽前体(NT-proBNP)水平对动脉瘤性蛛网膜下腔出血(aSAH)患者预后的评估价值。方法:选择80例aSAH患者,检测并记录患者发病后第1、3、7天脑脊液乳酸浓度,收集患者血常规、肝肾功能、心肌酶、血气分析等指标。3个月后对患者进行随访,根据格拉斯哥预后评分将其分为预后良好组和预后不良组,比较2组患者以上指标,绘制受试者工作特征(ROC)曲线,分析脑脊液乳酸联合血cTnI、NT-proBNP对预后的评估价值。结果:80例患者中预后良好45例,预后不良35例。预后良好组第1、3天脑脊液乳酸浓度明显低于预后不良组(P<0.05),ROC曲线分析显示第1天脑脊液乳酸浓度对aSAH预后的评估效能优于第3天、第7天,曲线下面积(AUC)分别为0.842、0.657、0.533。预后良好组患者血尿素氮、血糖、pH、cTnI、NT-proBNP明显低于预后不良组(P均<0.05),ROC曲线分析显示第1天脑脊液乳酸浓度联合血cTnI、NT-proBNP对预后的评估效能最高,AUC为0.94,灵敏度88.6%,特异性88.9%,优于尿素氮、血糖、pH及单项cTnI和NT-proBNP。结论:脑脊液中乳酸浓度联合血cTnI、NT-proBNP水平对aSAH预后有较高的预测价值。

关键词：动脉瘤性蛛网膜下腔出血脑脊液乳酸肌钙蛋白Ⅰ N末端脑钠肽前体

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Polarization Mechanism of Oxygen Vacancy and Its Influence on Dielectric Properties in ZnO

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Chinese Physics Letters 2011年第2期28卷 179-182页

作者： WANG li-Na FANG Xiao-Yong HOU Zhi-ling li ya-lin WANG Kun YUAN Jie CAO Mao-Sheng School of Science Yanshan UniversityQinhuangdao 066004 School of Materials Science and Engineering Beijing Institute of TechnologyBeijing 100081 School of Information Engineering Central University for NationalitiesBeijing 100081

We report on the mechanism of the dielectric properties of oxygen vacancy in ZnO,using ab initio numerical simulations of oxygen vacancy on the band structure and dielectric properties,to develop photoelectric material *** is revealed that the appearance of oxygen vacancies leads to wider energy band gap,obvious blue shift and increase in the peak of dielectric function as compared to the intrinsic ZnO *** explain these unusual phenomena and analyze the dielectric changes with the mechanism of polarization in the *** is shown that the main mechanism of influencing dielectric properties is the electron displacement *** result may be helpful for development of photoelectric materials.

关键词： materials dielectric vacancy

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Ground state of Rydberg-dressed Bose gas confined in a toroidal trap

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Communications in Theoretical Physics 2024年第1期76卷 29-35页

作者： lin-Xue Wang Hong-li yang Hui liu Si-lin Chen ya-Jun Wang Xiao-Fei Zhang Department of Physics School of Physics and Information ScienceShaanxi University of Science and TechnologyXi'an 710021China Department of Basic Sciences Air Force Engineering UniversityXi'an 710051China

The experimental realization of Rydberg dressing technology in ultracold atomic systems provides another superior platform for studying novel states of matter and macroscopic quantum *** this work,based on the mean-field theory,we have investigated the ground-state phases of a two-component Bose–Einstein condensate with Rydberg interaction and confined in a toroidal *** effects of the Rydberg interaction and external potential,especially the Rydberg blockade radius,on the ground-state structure of such a system have been investigated in full parameter *** results show that the Rydberg blockade radius,which can be regarded as another controllable parameter,can be used to obtain a variety of ground-state *** interestingly,it is found that for weak Rydberg interactions,the Rydberg blockade radius breaks the spontaneous rotational symmetry of the system,leading to the formation of a discrete unit cell *** strongly interacting cases,it can be used to realize different orders of discrete rotational symmetry breaking.

关键词： Bose-Einstein condensate Rydberg dressing toroidal trap

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Copper-based electro-catalytic nitrate reduction to ammonia from water:Mechanism,preparation,and research directions

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Environmental Science and Ecotechnology 2024年第4期20卷 42-62页

作者： Jinshan Wei Yi li Hexing lin Xihui Lu Chucheng Zhou ya-yun li Shenzhen Key Laboratory of Special Functional Materials&Shenzhen Engineering Laboratory for Advance Technology of Ceramics College of Materials Science and EngineeringShenzhen UniversityShenzhen518060PR China

Global water bodies are increasingly imperiled by nitrate pollution,primarily originating from industrial waste,agricultural runoffs,and urban *** escalating environmental crisis challenges traditional water treatment paradigms and necessitates innovative ***-catalysis,especially utilizing copper-based catalysts,known for their efficiency,cost-effectiveness,and eco-friendliness,offer a promising avenue for the electro-catalytic reduction of nitrate to *** this review,we systematically consolidate current research on diverse copper-based catalysts,including pure Cu,Cu alloys,oxides,single-atom entities,and ***,we assess their catalytic performance,operational mechanisms,and future research directions to find effective,long-term solutions to water purification and ammonia ***-catalysis technology shows the potential in mitigating nitrate pollution and has strategic importance in sustainable environmental *** to the application,challenges regarding complexity of the real water,the scale-up of the commerical catalysts,and the efficient collection of produced NH3 are still *** reseraches of catalyst specially on long term stability and in situ mechanisms are proposed.

关键词： Water treatment Nitrate removal Electrocatalysis Cu catalysts Ammonia synthesis

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