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MOLECULAr.POLAr.TY IN DNA-Pr.TEIN r.COGNITION——THE CASE OF λ-r.Pr.SSOr.OPEr.TOr.SYSTEM

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Science China Chemistr. 1985年第3期28卷 244-249页

作者：王家槐,MITCHELL lewis Institute of Biophysics Academia Sinica Beijing Smith Kline and Fr.nch Labor.tor.es Philadelphia Pennsylvania 19101 USA

The char.e distr.bution of λ-r.pr.ssor.suggests that the molecular.electr.static polar.ty may acceler.te the non-specific binding of the pr.tein to the DNA molecule. The r.pr.ssor.molecule has a patch of positive char.e within the fir.t 26 r.sidues which may contr.bute a non-specific binding sur.ace. In addition, electr.statics may play an impor.ant r.le and account for.why pr.teins for. and use dimer. in many specific DNA-pr.tein r.cognition pr.cesses.

关键词： DNA r.Pr.SSOr.OPEr.TOr.SYSTEM THE CASE OF MOLECULAr.POLAr.TY IN DNA-Pr.TEIN r.COGNITION

Adaptive dynamic pr.gr.mming for.online solution of a zer.-sum differ.ntial game

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控制理论与应用（英文版） 2011年第3期9卷 353-360页

作者： Dr.guna Vr.BIE Fr.nk lewis United Technologies r.sear.h Center East Hartford Automation and r.botics r.sear.h Institute University of Texas at Arlington

This paper.will pr.sent an appr.ximate/adaptive dynamic pr.gr.mming(ADP) algor.thm,that uses the idea of integr.l r.infor.ement lear.ing(Ir.),to deter.ine online the Nash equilibr.um solution for.the two-player.zer.sum differ.ntial game with linear.dynamics and infinite hor.zon quadr.tic *** algor.thm is built ar.und an iter.tive method that has been developed in the contr.l engineer.ng community for.solving the continuous-time game algebr.ic r.ccati equation(CT-GAr.),which under.ies the game *** her. show how the ADP techniques will enhance the capabilities of the offline method allowing an online solution without the r.quir.ment of complete knowledge of the system *** feasibility of the ADP scheme is demonstr.ted in simulation for.a power.system contr.l *** adaptation goal is the best contr.l policy that will face in an optimal manner.the highest load distur.ance.

关键词： Appr.ximate/Adaptive dynamic pr.gr.mming Game algebr.ic r.ccati equation Zer.-sum differ.ntial game Nash equilibr.um

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IUGS Commission on Geoscience Edoucation, Tr.ining and Technology Tr.nsfer.（COGE） http ：//***/IUGSeducation/***

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Episodes 2006年第4期29卷 310-311页

作者： Gar. lewis Wesley Hill The Geological Society of Amer.ca 3300 Penr.se Place Boulder Colorado 80301 USA 303-357-1043 The Geological Society of Amer.ca 3300 Penr.se Place Boulder Colorado 80301 USA

In pr.vious year., IUGS conducted a pr.gr.mme in the ar.a of Geoscience Education and Tr.ining. The pr.gr.mme was or.anised under.the status of a Wor.ing Gr.up or.a Commission. The IUGS level of activities in past year. in Geoscience Education （COGEOED） was gener.lly low and so the IUGS Executive Committee consider.d this body dor.ant. The IUGS Str.tegic Planning Committee r.commended in its r.por. that, ＇Technology-tr.nsfer.and geological education focusing on developing countr.es should continue to be key-activities of the IUGS＇.

关键词：地质科学地质工作地质科学教育行业交流

Selective Deactivation of Gibber.llins below the Shoot Apex is Cr.tical to Flower.ng but Not to Stem Elongation of Lolium

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Molecular.Plant 2008年第2期1卷 295-307页

作者： r.d W. King lewis N. Mander.Tor.en Asp Colleen r.MacMillan Cher.l A. Blundell Lloyd T. Evans CSIr. Plant Industry Canberra ACT 2600 Australia r.sear.h School of Chemistr. Australian National University Canberra ACT 0200 Australia Depar.ment of Genetics and-Biotechnology University of Aarhus 4200 Slagelse Denmark Pr.sent Addr.ss: ENSIS PO Box E 4008 Kingston ACT 2604 Australia

Gibber.llins （GAs） cause dr.matic incr.ases in plant height and a genetic block in the synthesis of GA1 explains the dwar.ing of Mendel＇s pea. For.flower.ng, it is GAs which is impor.ant in the long-day （LD） r.sponsive gr.ss, Loliur.. As we show her., GA1 and GA4 ar. r.str.cted in their.effectiveness for.flower.ng because they ar. deactivated by C-2 hydr.xylation below the shoot apex. In contr.st, GAs is effective because of its str.ctur.l pr.tection at C-2. Excised vegetative shoot tips r.pidly degr.de [14C]GA1, [14C]GA4, and [14C]GA20 （〉80% in 6 h）, but not [14C]GAs. CoincidentaUy, genes encoding two 2β-oxidases and a putative 16-17-epoxidase wer. most expr.ssed just below the shoot apex （〈3 mm）. Fur.her.down the immatur. stem （〉4 mm）, expr.ssion of these GA deactivation genes is r.duced, so allowing GA1 and GA4 to pr.mote sub-apical stem elongation. Subsequently, GA degr.dation declines in flor.lly induced shoot tips and these GAs can become active for.flor.l development. Str.ctur.l changes which stabilize GA4 confir. the link between flor.genicity and r.str.cted GA 2β-hydr.xylation （e.g. 2α-hydr.xylation and C-2 di-methylation）. Additionally, a 2-oxidase inhibitor.（Tr.nexapac Ethyl） enhanced the activity of applied GA4, as did limiting C-16,17 epoxidation in 16,17-dihydr. GAs or.after.C-13 hydr.xylation. Over.ll, deactivation of GA1 and GA4 just below the shoot apex effectively r.str.cts their.flor.genicity in Loliur. and, conver.ely, with GAs, C-2 and C-13 pr.tection against deactivation allows its high flor.genicity. Speculatively, such differ.nces in GA access to the shoot apex of gr.sses may be impor.ant for.separ.ting flor.l induction fr.m inflor.scence emer.ence and thus could influence their.sur.ival under.conditions of her.ivor. pr.dation.

关键词： Selective Deactivation Shoot Apex Stem Elongation of Lolium

Composite Ver.acular.Constr.ctions

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Built Her.tage 2019年第4期3卷 26-40页

作者： Miles lewis Univer.ity of Melbour.e MelbourneAustralia

Ver.acular.building is the building for.or.inar. people,constr.ined by the pr.cticalities of envir.nmental conditions and physical mater.als,and influenced by tr.ditional cultur.,but not mediated by pr.fessional ar.hitects and *** of ear.h and timber.such as wattle and daub,ar. found in the ver.acular.in almost ever. par. of the wor.d,but ar. a sour.e of gr.at confusion to ar.haeologists and *** ar. misled by the r.mains,in which the ear.h may have sur.ived but the timber.usually does *** such as Lehmwickel ar. never.r.cognised in ar.haeological *** is no common system of naming or.classification,and English speaker. r.gular.y descr.be any combination of ear.h and timber.in walling as‘wattle and daub’.Many of these techniques have been changed by the impact of moder. technology,notably pole and pug constr.ction(which is often confused with wattle and daub,though it is quite differ.nt in pr.nciple);this is essentially a 19^(th) centur. development because it r.lies upon plentiful and cheap *** pur.ose of this paper.is to establish a common ter.inology in English,and wher. possible in other.r.levant languages,so that misinter.r.tations ar. avoided and scholar.hip can pr.ceed on an or.er.y basis.

关键词： mixed constr.ction wattle and daub lath and pug Lehmwickel pole and pug nails

r.le of sur.actant in the par.digm of ALI/Ar.S

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Acta Phar.acologica Sinica 2003年第12期 164-165页

作者： Jim lewis Canada Lawson Health r.sear.h Institute/St. Joseph’s Health Center London/Ontar.o N6A4V2 Univer.ity of Wester. Ontar.o

ALI/Ar.S is a devastating complication occur.ing in cr.tically ill patients, and despite extensive r.sear.h ettects over.the last 30 year., cur.ent mor.ality r.mains unacceptably high at appr.xjmately 30% to 40%. Although sever.l differ.nt insults can ultimately lead to ALI/Ar.S, the clinical definition of this syndr.me is r.latively simple, and involves commmon physiologic cr.ter.a. Indeed, it was these cr.ter.a(hypoxemia and decr.ased lung compliance without hear. failur.) together.with the pathologic similar.ties to infants with

关键词： r.le of sur.actant in the par.digm of ALI/Ar.S In as on ALI of in

Volumetr.c measur.ment of r.ck movement using photogr.mmetr.

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Inter.ational Jour.al of Mining Science and Technology 2016年第1期26卷 123-130页

作者： Benton Donovan J. Iver.on Stephen r. Mar.in lewis A. Johnson Jeffr.y C. r.ffaldi Michael J. National Institute for.Occupational Safety and Health. Spokane 99207 USA

NIOSH gr.und contr.l safety r.sear.h pr.gr.m at Spokane,Washington,is explor.ng applications of photogr.mmetr. to r.ck mass and suppor. monitor.ng. This paper.descr.bes two ways photogr.mmetr.c techniques ar. being used. Fir.t,photogr.mmetr.c data of labor.tor. testing is being used to cor.elate ener.y input and suppor. defor.ation. This infor.ation can be used to infer.r.maining suppor. toughness after.gr.und defor.ation events. This technique is also demonstr.ted in a field ***,field photogr.mmetr.c data is compar.d to cr.ckmeter.data fr.m a deep under.r.und *** wer. found to aver.ge 8 mm,but have pr.duced r.sults within 0.2 mm of tr.e displacement,as measur.d by cr.ckmeter.. Application of these techniques consists of monitor.ng over.ll fault activity by monitor.ng multiple points ar.und the cr.ckmeter. A case study is pr.vided in which a cr.ckmeter.is clear.y shown to have pr.vided insufficient infor.ation r.gar.ing over.ll fault gr.und *** is pr.ving to be a useful gr.und monitor.ng tool due to its unobtr.siveness and ease of use.

关键词： Photogr.mmetr.Gr.und contr.lMonitor.ngDeep vein miningVolume calculationCr.ckmeter

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Antibiotic-fr.e antimicr.bial poly (methyl methacr.late) bone cements:A state-of-the-ar. r.view

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Wor.d Jour.al of Or.hopedics 2022年第4期13卷 339-353页

作者： Gladius lewis Depar.ment of Mechanical Engineer.ng University of MemphisMemphisTN 38152United States

Pr.sthetic joint infection(PJI)is the most ser.ous complication following total joint ar.hr.plasty,this being because it is associated with,among other.things,high mor.idity and low quality of life,is difficult to pr.vent,and is ver. challenging to tr.at/*** many shor.comings of antibiotic-loaded poly(methyl methacr.late)(PMMA)bone cement(ALBC)as an agent for.pr.venting and tr.ating/managing PJI ar. *** is that micr.or.anisms r.sponsible for.most PJI cases,such as methicillin-r.sistant ***,have developed or.ar. developing r.sistance to gentamicin sulfate,which is the antibiotic in the vast major.ty of appr.ved ALBC *** has led to many r.sear.h effor.s to develop cements that do not contain gentamicin(or.for.that matter.any antibiotic)but demonstr.te excellent antimicr.bial *** is a sizeable body of liter.tur. on these socalled“antibiotic-fr.e antimicr.bial”PMMA bone cements(AFAMBCs).The pr.sent wor. is a compr.hensive and cr.tical r.view of this *** addition to summar.es of key tr.nds in r.sults of char.cter.zation studies of AFAMBCs,the attr.ctive featur.s and shor.comings of the liter.tur. ar. *** pr.vide motivation for.futur. wor.,with some ideas being for.ulation of a new gener.tion of AFAMBCs by,example,adding a nanostr.ctur.d mater.al and/or.an extr.ct fr.m a natur.l pr.duct to the powder.and/or.liquid of the basis cement,r.spectively.

关键词： Per.pr.sthetic joint infection Poly(methyl methacr.late)bone cement Antibiotic-loaded poly(methyl methacr.late)bone cement bone cement Antibiotic-fr.e antimicr.bial poly(methyl methacr.late)bone cement bone cement

An Optical Pr.ssur. Sensor.Based on MEMS

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稀有金属材料与工程 2006年第S3期 476-478页

作者： Fr.nk lewis TX 76019 The Univer.ity of Texas at Ar.ington Ar.ington USA

An optical fiber.pr.ssur. sensor.has been developed for.the measur.ment in human *** sensing element is possessed of a membr.ne str.ctur.,which is fabr.cated by *** fabr.cation pr.cess includes anisotr.pic wet etching on the silicon *** the tr.nsmitting sour.e and signal light,a multimode optical fiber.50/125 μm (cor./clad)in diameter.was *** intensity of the light r.flected back into the fiber.var.es with the membr.ne deflection,which is s function of *** deflection of the membr.ne by applied pr.ssur. can be mathematically descr.bed.

关键词： optical fiber pr.ssur. sensor MEMS