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The Structure of Gelsolin Bound to ATP

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The Structure of Gelsolin Bound to ATP

The 4th ISGO International Conference on Structural Genomics

作者： dunja Urosev Agnes L.C.Tan Robert C.Robinson leslie d.Burtnick department of Chemistry and Centre for Blood Research The University of British Columbia VancouverBC V6T 1Z1Canada Institute of Molecular and Cell Biology 61 Biopolis drive ProteosSingapore 138673 department of Medical Biochemistry and Microbiology Uppsala Biomedical Center Uppsala University Uppsala 751 23 Sweden Institute of Molecular and Cell Biology61 Biopolis Drive Proteos Singapore 138673 department of Chemistry and Centre for Blood Research The University of British Columbia Vancouver BC V6T 1Z1Canada

＜正＞Calcium activation of the actin-modifying properties of gelsolin is sensitive to ATP. Here, we show that soaking calcium-free gelsolin crystals in ATP-containing media results in ATP occupying a site that spans the two pseudosymmetrical halves of the protein. ATP binding involves numerous polar and hydrophobic contacts and is

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当代护理知识测验

国际护理学杂志 1987年第1期08卷 43-44页

作者： leslie d. ATKINSON ,李应中

1.人体最大的能量来源: a.蛋白质b.肪脂c.维生紧d.碳水化合物2.胃肠道吸收营养最好的部位: a.口腔b.胃c.小肠d.大肠3.下列哪一项的人体液占体重的最大百分数? a.85岁的老人b.9磅初生婴儿c.超体重的少女d.36岁的马拉松赛跑者4.脑垂体肿大... 详细信息

1.人体最大的能量来源: a.蛋白质b.肪脂c.维生紧d.碳水化合物2.胃肠道吸收营养最好的部位: a.口腔b.胃c.小肠d.大肠3.下列哪一项的人体液占体重的最大百分数? a.85岁的老人b.9磅初生婴儿c.超体重的少女d.36岁的马拉松赛跑者4.脑垂体肿大,抗利尿激素释放到血内减少,可

关键词：镇静剂食物病人

dETERM INATION OF THE STABILITY CONSTANTS OF COMPLEXES OF HISTIdINE,SOME dIPEPTIdES ANd TRIGLYCINE WITH Zn(Ⅱ)ANd Cd(Ⅱ)USING SMALL-SCALE PH-METRIC TITRATIONS

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Chinese Chemical Letters 1991年第9期2卷 723-724页

作者： Ai Ru LU department of Chemistry,Northwest Normal University,Lanzhou,730070 leslie d.PETTIT Jan E.GREGOR School of Chemistry,The University,Leeds LS2 9JT,U.K

A potentiometric study on the complexes of His,Gly-His,ALa-His,Gly-Gly and Gly—Gly—Gly with Zn(Ⅱ)and Cd(Ⅱ)has been ***-scale potentiometric titrations were car- ried out to determine stabil ity constants of complexes at 25℃ with I=0.10 mol dm^(-3)(KNO_3).The com- puter programs SUPERQUAd were applied for data treatment with satisfactory results.

关键词： Gly dETERM INATION OF THE STABILITY CONSTANTS OF COMPLEXES OF HISTIdINE,SOME dIPEPTIdES ANd TRIGLYCINE WITH Zn ANd Cd USING SMALL-SCALE PH-METRIC TITRATIONS

Rigidity Symmetry Line for Thermodynamic Fluid Equations-of-State

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Journal of Modern Physics 2024年第5期15卷 613-633页

作者： leslie V. Woodcock department of Physics University of Algarve Faro Portugal

We report progress towards a modern scientific description of thermodynamic properties of fluids following the discovery (in 2012) of a coexisting critical density hiatus and a supercritical mesophase defined by percolation transitions. The state functions density ρ(p,T), and Gibbs energy G(p,T), of fluids, e.g. CO2, H2O and argon exhibit a symmetry characterised by the rigidity, ω = (dp/dρ)T, between gaseous and liquid states along any isotherm from critical (Tc) to Boyle (TB) temperatures, on either side of the supercritical mesophase. Here, using experimental data for fluid argon, we investigate the low-density cluster physics description of an ideal dilute gas that obeys dalton’s partial pressure law. Cluster expansions in powers of density relate to a supercritical liquid-phase rigidity symmetry (RS) line (ω = ρrs(T) = RT) to gas phase virial coefficients. We show that it is continuous in all derivatives, linear within stable fluid phase, and relates analytically to the Boyle-work line (BW) (w = (p/ρ)T = RT), and to percolation lines of gas (PB) and liquid (PA) phases by: ρBW(T) = 2ρPA(T) = 3ρPB(T) = 3ρRS(T)/2 for T TB. These simple relationships arise, because the higher virial coefficients (bn, n ≥ 4) cancel due to clustering equilibria, or become negligible at all temperatures (0 T TB) within the gas phase. The Boyle-work line (p/ρBW)T is related exactly at lower densities as T → TB, and accurately for liquid densities, by ρBW(T) = −(b2/b3)T. The RS line, ω(T) = RT, defines a new liquid-density ground-state physical constant (ρRS(0) = (2/3)ρBW(0) for argon). Given the gas-liquid rigidity symmetry, the entire thermodynamic state functions below TB are obtainable from b2(T). A BW

关键词： Liquid-State Theory Cluster Physics Percolation Lines Fluid Thermodynamics Boyle Line Rigidity-Symmetry Line

A COMPARISON OF THE dETERMINATION OF STABILITY CONSTANTS OF COMPLEXES OF Cd(Ⅱ)WITH AMINO ACIdS ANd SIMPLE PEPTIdES USING MICRO—pH—METRIC TITRATIONS ANd CYCLIC VOLTAMMETRY

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Chinese Chemical Letters 1993年第10期4卷 933-934页

作者： Ai Ru LU department of Chemistry,Northwest University,Lanzhou,730070leslie d.PETTIT Gareth BERNARd Jan E.GREGOR School of Chemistry,The University of Leeds,Leeds,LS2,9JT,U.K.

This paper reports the determination of stability constants for complexes of Cd(Ⅱ)with Gly, Ala,Val,Asp,Gly—Asp,Asp Gly,Gly—Gly and Gly—Gly—Gly using both micro—pH—metric titra- tions and the application of convolution—deconvolution cyclic voltammetry at 25℃ and I=0.10 mol· dm^(-3)(KNO_3).Stability constants were calculated from pH—metric data using the SUPERQUAd com- puter program and cyclic voltammograms were collected,stored and manipulated using the EG and G CONdECON 300 software.A considerably larger ligand:metal ratio(e,g.50:1)was possible using *** of results from the two techniques suggests that stability constants for the species[CdL_2]and[CdL_3]are reliable when calculated fromvoltammetry while those for[CdL]are more reliable when determined by pH-metric titration.

关键词： A COMPARISON OF THE dETERMINATION OF STABILITY CONSTANTS OF COMPLEXES OF Cd METRIC TITRATIONS ANd CYCLIC VOLTAMMETRY WITH AMINO ACIdS ANd SIMPLE PEPTIdES USING MICRO pH

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耶稣与我们

美国法律事务所的有限责任合伙制及美国法律事务所组织形式的选择

1941年

作者：魏德海（leslie d.Weatherhead）夏明如译

书名原文:Jesus and ourselves:有耶稣尊重我们的人格，耶稣关心我们的自尊，耶稣与我们的影响等，共18章。

关键词：哲学、宗教宗教基督教

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美国法律事务所的有限责任合伙制及美国法律事务所组织形式的选择

Recent Ventures in Interdisciplinary Arctic Research:The ARCPATH Project

作者： leslie d.Corwin Arthur J.Ciampi 张沧美国律师协会国家知识产权局专利复审委员会

有限责任合伙制是美国最近几年发展起来的一种法律事务所组织形式,它具有普通合伙的一般特点,又在一定程度上为合伙人提供了只有有限责任制股东才享有的代理责任保护,正是LLP这种灵活性的规定,美国新成立的法律事务所越来越多地选择这...

有限责任合伙制是美国最近几年发展起来的一种法律事务所组织形式,它具有普通合伙的一般特点,又在一定程度上为合伙人提供了只有有限责任制股东才享有的代理责任保护,正是LLP这种灵活性的规定,美国新成立的法律事务所越来越多地选择这一组织形式,许多原来的普通合伙法律事务所也转换成了有限责任合伙制。本文是一篇介绍美国法律事务所有限责任合伙制的译文,同时还附有介绍美国法律事务所选择组织形式时所考虑因素的内容。通过本文的介绍,旨在帮助读者了解美国法律事务所的组织形式及选择,同时也为我国法律服务机构组织机构的立法以及法律服务机构选择合适的组织形式提供借鉴。

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Advances in Atmospheric Sciences 2024年第8期41卷 1559-1568页

作者： Astrid E.J.OGILVIE leslie A.KING Noel KEENLYSIdE François COUNILLON Brynhildur dAVIÐSdÓTTIR Níels EINARSSON Sergey GULEV Ke FAN Torben KOENIGK James R.MCGOOdWIN Marianne H.RASMUSSON Shuting YANG Institute of Arctic and Alpine Research(INSTAAR) University of ColoradoBoulder CO 80303USA Stefansson Arctic Institute AkureyriÍS-600Iceland Royal Roads University BC V9B 5Y2Canada University of Bergen Bergen N-5007Norway Nansen Environmental and Remote Sensing Centre Bergen N-5007Norway University of Iceland Reykjavík 102Iceland Shirshov Institute of Oceanology Moscow 117218Russia Moscow State University Moscow 11991Russia Chinese Academy of Sciences Beijing 100045China Swedish Meteorological and Hydrological Institute SE-60176 NorrköpingSweden danish Meteorological Institute CopenhagenØ2100Denmark Obukhov Institute of Atmospheric Physics RAS119017MoscowRussia

This paper celebrates Professor Yongqi GAO's significant achievement in the field of interdisciplinary studies within the context of his final research project Arctic Climate Predictions: Pathways to Resilient Sustainable Societies-ARCPATH(https://***/en/projects/finished-projects/arcpath). The disciplines represented in the project are related to climatology, anthropology, marine biology, economics, and the broad spectrum of social-ecological studies. Team members were drawn from the Nordic countries, Russia, China, the United States, and Canada. The project was transdisciplinary as well as interdisciplinary as it included collaboration with local knowledge holders. ARCPATH made significant contributions to Arctic research through an improved understanding of the mechanisms that drive climate variability in the Arctic. In tandem with this research, a combination of historical investigations and social, economic, and marine biological fieldwork was carried out for the project study areas of Iceland, Greenland, Norway, and the surrounding seas, with a focus on the joint use of ocean and sea-ice data as well as social-ecological drivers. ARCPATH was able to provide an improved framework for predicting the near-term variation of Arctic climate on spatial scales relevant to society, as well as evaluating possible related changes in socioeconomic realms. In summary, through the integration of information from several different disciplines and research approaches, ARCPATH served to create new and valuable knowledge on crucial issues, thus providing new pathways to action for Arctic communities.

关键词： Recent Ventures in Interdisciplinary Arctic Research:The ARCPATH Project

diversity of Arbuscular Mycorrhizal Fungi Species Associated with Soybean (Glycine max L. Merill) in Benin

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American Journal of Plant Sciences 2022年第5期13卷 686-701页

作者： Howell B. Houngnandan Appolinaire Adandonon Trévis S. B. Adoho leslie d. R. Bossou Adélaïde H. Fagnibo Oslo S. Gangnon Moriaque Akplo Charlotte M. Zoundji Félix Kouèlo Adolphe Zeze Pascal Houngnandan Laboratoire des Sciences Végétale Horticole et Forestière (LaSVHF) Université Nationale d’Agriculture (UNA) Kétou République du Bénin Laboratoire de Microbiologie des Sols et d’Ecologie Microbienne Faculté des Sciences Agronomiques de l’Université d’Abomey-Calavi (UAC) Abomey-Calavi République du Bénin Laboratoire de Biotechnologies Végétale et Microbienne Unité Mixte de Recherche et d’Innovation en Sciences Agronomiques et Génie Rural Institut National Polytechnique Felix Houphou&#235 t-Boigny (INPHB C&#244 te d’Ivoire) Yamoussoukro C&#244 te d’Ivoire Ecole de Gestion et de Production Vegetale et Semenciere (EGPVS) Université Nationale d’Agriculture (UNA) Kétou République du Bénin

Arbuscular Mycorrhizal Fungi (AMFs) could be used to sustainably improve crop yields. The present study evaluated the diversity of AMF species associated with soybean (Glycine max L. Merill) in main soybean-producing areas in Benin. Composite soil samples from 13 production areas at a rate of 04 villages per production areas were collected. A spore trapping device was set up to reveal the diversity of spores. The physical and chemical properties of the soils, the frequency and intensity of mycorrhization of roots, and the diversity of AMF spores were determined in the soil samples following trapping. As result, eight morphotypes belonging to four genera: Glomus, Acaulospora Gigaspora and disversispora and three families: diversisporales, Glomérales and Paraglomérales were observed. An important variability of spore densities was observed from one production areas to another with a higher abundance in the production areas of Copargo estimated at 3584 spores/100g soil. The biological diversity indexes as Shannon (0.0311), Simpson (0.0204) and Hill (0.0235), varied significantly (p duction areas to another. There was significant correlation between the parameters studied, particularly between the physico-chemical parameters of the soils and between the physico-chemical parameters and the biological diversity indexes. For the mycorrhization parameters, the mycorhization frequencies did not vary from one production areas to another, unlike the intensities, which significantly varied from one production areas to another (2.31% to 24.62%). Finally, this study revealed that the physico-chemical parameters of the soils had an influence on the other parameters studied. Moreover, there were an abundance and a significant diversification of AMFs associated with soybean in the different production areas, which are influenced by certain physico-chemical soil parameters.

关键词： Arbuscular Mycorrhizal Fungi (AMFs) Soybean Spore density diversity