检索结果-南通市图书馆

Overview of genetic signaling pathway interactions within cutaneous malignancies

Journal of Cancer Metastasis and Treatment 2020年第1期6卷 440-479页

作者： Brittany S.Maner leonie dupuis Ashley Su Jeremy J Jueng Tanner P.Harding John Meisenheimer Ⅶ Fahad S.Siddiqui Mia R.Hardack Savina Aneja James A.Solomon Ross University School of Medicine MiramarFL 33027USA Ameriderm Research Ormond BeachFL 32174USA University of Central Florida College of Medicine OrlandoFL 32827USA University of South Florida Morsani College of Medicine TampaFL 33612USA Alabama College of Osteopathic Medicine DothanAL 36303USA Advanced Dermatology and Cosmetic Surgery OrlandoFL 32806USA Florida State University College of Medicine OrlandoFL 32304USA Kansas City University of Medicine&Biosciences Kansas CityMO 64106USA Carle-Illinois College of Medicine UrbanaIL 61820USA

Melanoma and non-melanoma cutaneous malignancies are some of the leading causes of cancer-related death in the United *** melanoma is more known to have a high mortality rate,the total mortality per year is nearly equal for between melanoma and non-melanoma skin ***,the non-melanoma types of cutaneous malignancies have potential to become locally invasive and even metastasize with very little to no treatment options when *** development of these malignancies involves various genetic pathways through the four hallmarks of cancer development:malignant cell growth,apoptosis evasion,the use of supporting stroma and vascularization,and modulating and promoting an inadequate immune *** genetic signaling pathways of basal cell carcinoma,squamous cell carcinoma,verrucous carcinoma,basosquamous cell carcinoma,melanoma,and cutaneous T-cell lymphoma interact with each other through genetic predisposition as well as with environmental ***,solar ultraviolet radiation and chronic inflammatory states are found to initiate the progression of many of these cutaneous *** paper includes validated models of genetic pathways,emerging pathways,and crosstalk between genetic pathways through the four hallmarks of cancer ***,unlike most reviews addressing oncogenetics of the well-recognized,as well as newly discovered,genetic pathway mutations,this review stresses that these pathways are not fixed but rather exist in dynamic,interrelated,interactive,complex,and adaptive flux states.

关键词： Basal cell carcinoma squamous cell carcinoma verrucous carcinoma basosquamous cell carcinoma melanoma cutaneous T-cell lymphoma genetic pathways cancer hallmarks

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：