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Unlocking the out-of-plane dimension for photonic bound states in the continuum to achieve maximum optical chirality

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Light(science & Applications) 2023年第11期12卷 2423-2433页

作者： Lucca Kühner Fedja J.Wendisch Alexander A.Antonov Johannes Bürger Ludwig Hüttenhofer leonardo de s.menezes.s.efan a.maier Maxim V.Gorkunov Yuri Kivshar Andreas Tittl Chair in Hybrid Nanosystems Nanoinstitute Munichand Center for NanoScienceFaculty of PhysicsLudwig-Maximilians-University MunichKöniginstrasse 1080539 MünchenGermany shubnikov Institute of Crystallography FSRC“Crystallography and Photonics”Russian Academy of SciencesMoscow 119333Russia departamento de Física Universidade Federal de Pernambuco50670-901 RecifePernambucoBrazil school of Physics and Astronomy Monash UniversityWellington RdClaytonVIC 3800Australia The Blackett Laboratory Department of PhysicsImperial College LondonLondon SW72AZUK Nonlinear Physics Centre Research School of PhysicsAustralian National UniversityCanberraACT 2601Australia

The realization of lossless metasurfaces with true chirality crucially requires the fabrication of three-dimensional structures,constraining experimental feasibility and hampering practical *** though the threedimensional assembly of metallic nanostructures has been demonstrated previously,the resulting plasmonic resonances suffer from high intrinsic and radiative *** concept of photonic bound states in the continuum(BICs)is instrumental for tailoring radiative losses in diverse geometries,especially when implemented using lossless dielectrics,but applications have so far been limited to planar ***,we introduce a novel nanofabrication approach to unlock the height of individual resonators within all-dielectric metasurfaces as an accessible parameter for the efficient control of resonance features and nanophotonic *** particular,we realize out-of-plane symmetry breaking in quasi-BIC metasurfaces and leverage this design degree of freedom to demonstrate an optical all-dielectric quasi-BIC metasurface with maximum intrinsic chirality that responds selectively to light of a particular circular polarization depending on the structural *** experimental results not only open a new paradigm for all-dielectric BICs and chiral nanophotonics,but also promise advances in the realization of efficient generation of optical angular momentum,holographic metasurfaces,and parity-time symmetry-broken optical systems.

关键词： dielectric symmetry realization

New insights into plasmonic hot-electron dynamics

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Light(science & Applications) 2024年第11期13卷 2427-2430页

作者： Dangyuan Lei Dong su stefan a.maier department of Materials science and Engineering Center for Functional Photonicsand Hong Kong Branch of National Precious Metals Material Engineering Research CentreCity University of Hong Kong83 Tat Chee AvenueHong Kong S.A.R.999077China school of Physics and Astronomy Monash UniversityClayton 3800 VICAustralia Blackett Laboratory Imperial College LondonLondon SW72AZUK

Recent advances in understanding the hot-electron dynamics in plasmonic nanostructures have significantly impacted a variety of plasmonically powered physical,chemical,and even biological *** insights into their quant... 详细信息

关键词： dynamics plasmon insight

Nanophotonics shines light on hyperbolic metamaterials

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Light(science & Applications) 2022年第2期11卷 145-148页

作者： Andreas Aigner Judith M.Dawes stefan a.maier Haoran Ren Chair in Hybrid Nanosystems Nanoinstitute MunichFaculty of PhysicsLudwig-Maximilians-University MunichMunich 80539Germany MQ Photonics Research Centre Department of Physics and AstronomyMacquarie UniversityMacquarie ParkNSW 2109Australia.3Department of PhysicsImperial College LondonLondon SW72AZUK 不详

Hyperbolic metamaterials with a unique hyperbolic dispersion relation allow propagating waves with infinitely largewavevectors and a high density of states. Researchers from Korea and singapore provide a comprehensive review ofhyperbolic metamaterials, including artificially structured hyperbolic media and natural hyperbolic materials. Theyexplain key nanophotonic concepts and describe a range of applications for these versatile materials.

关键词： materials. hyperbolic infinitely

Ultrahigh numerical aperture meta-fibre for flexible optical trapping

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Light(science & Applications) 2021年第4期10卷 589-599页

作者： Malte Plidschun Haoran Ren Jisoo Kim Ronny Forster stefan a.maier Markus A.schmidt Leibniz Institute of Photonic Technology 07745 JenaGermany Abbe Center of Photonics and Faculty of Physics FSU Jena07745 JenaGermany Chair in Hybrid Nanosystems Nanoinstitute MunichLMU Munchen80539 MunchenGermany department of Physics Imperial College LondonLondon SW72AZUK Otto schott Institute of Material Research FSU Jena07745 JenaGermany

strong focusing on diffraction-limited spots is essential for many photonic applications and is particularly relevant for optical trapping;however,all currently used approaches fail to simultaneously provide flexible transportation of light,straightforward implementation,compatibility with waveguide circuitry,and strong ***,we demonstrate the design and 3D nanoprinting of an ultrahigh numerical aperture meta-fibre for highly flexible optical *** into account the peculiarities of the fibre environment,we implemented an ultrathin meta-lens on the facet of a modified single-mode optical fibre via direct laser writing,leading to a diffraction-limited focal spot with a recordhigh numerical aperture of up to NA≈*** unique capabilities of this flexible,cost-effective,bio-and fibre-circuitrycompatible meta-fibre device were demonstrated by optically trapping microbeads and bacteria for the first time with only one single-mode fibre in combination with diffractive *** study highlights the relevance of the unexplored but exciting field of meta-fibre optics to a multitude of fields,such as bioanalytics,quantum technology and life sciences.

关键词： optical waveguide fibre

Role of copper chelating agents: between old applications and new perspectives in neuroscience

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Neural Regeneration Research 2025年第3期20卷 751-762页

作者： Rosalba Leuci leonardo Brunetti Vincenzo Tufarelli Marco Cerini Marco Paparella Nikola Puvača Luca Piemontese department of Pharmacy-Pharmaceutical science University of Bari Aldo MoroBariItaly department of Precision and Regenerative Medicine and Jonian Area(DiMePRe-J) Section of Veterinary Science and Animal ProductionUniversity of Bari Aldo MoroBariItaly department of Engineering Management in Biotechnology Faculty of Economics and Engineering Management in Novi SadUniversity Business Academy in Novi SadNovi SadSerbia

The role of copper element has been an increasingly relevant topic in recent years in the fields of human and animal health, for both the study of new drugs and innovative food and feed supplements. This metal plays an important role in the central nervous system, where it is associated with glutamatergic signaling, and it is widely involved in inflammatory processes. Thus, diseases involving copper(Ⅱ) dyshomeostasis often have neurological symptoms, as exemplified by Alzheimer's and other diseases(such as Parkinson's and Wilson's diseases). Moreover, imbalanced copper ion concentrations have also been associated with diabetes and certain types of cancer, including glioma. In this paper, we propose a comprehensive overview of recent results that show the importance of these metal ions in several pathologies, mainly Alzheimer's disease, through the lens of the development and use of copper chelators as research compounds and potential therapeutics if included in multi-target hybrid drugs. seeing how copper homeostasis is important for the well-being of animals as well as humans, we shortly describe the state of the art regarding the effects of copper and its chelators in agriculture, livestock rearing, and aquaculture, as ingredients for the formulation of feed supplements as well as to prevent the effects of pollution on animal productions.

关键词： agriculture Alzheimer's disease chelators copper feed supplements multi-target

single-emitter super-resolved imaging of radiative decay rate enhancement in dielectric gap nanoantennas

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Light(science & Applications) 2024年第1期13卷 47-54页

作者： R.Margoth Córdova-Castro Bart van Dam Alberto Lauri stefan a.maier Riccardo sapienza Yannick de Wilde Ignacio Izeddin Valentina Krachmalnicoff Institut Langevin ESPCI ParisPSL UniversityCNRSParisFrance The Blackett Laboratory Department of PhysicsImperial College LondonLondonUK school of Physics and Astronomy Monash UniversityClaytonVictoriaAustralia Chair in Hybrid Nanosystems Ludwig-Maximilians Universität MünchenMuenchenGermany department of Physics University of OttawaOttawaONCanada

High refractive index dielectric nanoantennas strongly modify the decay rate via the Purcell effect through the design of radiative *** to their dielectric nature,the field is mainly confined inside the nanostructure and in the gap,which is hard to probe with scanning probe *** we use single-molecule fluorescence lifetime imaging microscopy(smFLIM)to map the decay rate enhancement in dielectric GaP nanoantenna dimers with a median localization precision of 14 *** measure,in the gap of the nanoantenna,decay rates that are almost 30 times larger than on a glass *** comparing experimental results with numerical simulations we show that this large enhancement is essentially radiative,contrary to the case of plasmonic nanoantennas,and therefore has great potential for applications such as quantum optics and biosensing.

关键词： dielectric decay radiative

single-step-fabricated disordered metasurfaces for enhanced light extraction from LEDs

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Light(science & Applications) 2021年第10期10卷 1840-1848页

作者： Peng Mao Changxu Liu Xiyan Li Mengxia Liu Qiang Chen Min Han stefan a.maier Edward H.sargent shuang Zhang school of Physics and Astronomy University of BirminghamB152TT BirminghamUK National Laboratory of solid state Microstructures College of Engineering and Applied Sciencesand Collaborative Innovation Centre of Advanced MicrostructuresNanjing UniversityNanjing 210093China Chair in Hybrid Nanosystems Nanoinstitute MunichFaculty of PhysicsLudwigMaximilians-Universitaet Muenchen80539 MuenchenGermany department of Electrical and Computer Engineering University of Toronto35 St.George StreetTorontoON M5S 1A4Canada Key Laboratory of Intelligent Optical sensing and Manipulation(Nanjing University) Ministry of EducationNanjingChina department of Physics Imperial College LondonLondon SW72AZUK department of Physics University of Hong KongHong Kong 999077China department of Electrical and Electronic Engineering University of Hong KongHong Kong 999077China

While total internal reflection(TIR)lays the foundation for many important applications,foremost fibre optics that revolutionised information technologies,it is undesirable in some other applications such as light-emitting diodes(LEDs),which are a backbone for energy-efficient light *** the case of LEDs,TIR prevents photons from escaping the constituent high-index *** in material science have led to good efficiencies in generating photons from electron–hole pairs,making light extraction the bottleneck of the overall efficiency of *** recent years,the extraction efficiency has been improved,using nanostructures at the semiconductor/air interface that outcouple trapped photons to the outside ***,the design of geometrical features for light extraction with sizes comparable to or smaller than the optical wavelength always requires sophisticated and timeconsuming fabrication,which causes a gap between lab demonstration and industrial-level *** by lightning bugs,we propose and realise a disordered metasurface for light extraction throughout the visible spectrum,achieved with single-step *** applying such a cost-effective light extraction layer,we improve the external quantum efficiency by a factor of 1.65 for commercialised GaN LEDs,demonstrating a substantial potential for global energy-saving and sustainability.

关键词： light backbone consuming

dendritic spine degeneration:a primary mechanism in the aging process

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Neural Regeneration Research 2025年第6期20卷 1696-1698页

作者： Gonzalo Flores leonardo Aguilar-Hernández Fernado García-Dolores Humberto Nicolini Andrea Judith Vázquez-Hernández Hiram Tendilla-Beltrán Instituto de Fisiología Benemérita Universidad Autónoma de Puebla(BUAP)PueblaMexico Instituto de Ciencias Forenses(INCIFO) Tribunal Superior de Justicia de la Ciudad de México(TSJCDMX).Mexico CityMexico Instituto Nacional de Medicina Genómica(INMEGEN) Mexico CityMexico

Recent reports suggest that aging is not solely a physiological process in living beings;instead, it should be considered a pathological process or disease(Amorim et al., 2022). Consequently, this process involves a wide range of factors, spanning from genetic to environmental factors, and even includes the gut microbiome(GM)(Mayer et al., 2022). All these processes coincide at some point in the inflammatory process, oxidative stress, and apoptosis, at different degrees in various organs and systems that constitute a living organism(Mayer et al., 2022;AguilarHernández et al., 2023).

关键词： aging process stress

King's College criteria and the Clichy-Villejuif criteria require adjustments for assessing acute liver failure due to yellow fever

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World Journal of Transplantation 2025年第1期15卷 124-134页

作者： Bruno da silva Athanasio Antonio Marcio de Faria Andrade Vivian Vasconcelos Costa Juliano Felix Castro silverio leonardo Macedo Garcia Mauro Martins Teixeira Daniele da Gloria souza Paula Vieira Teixeira Vidigal Cristiano Xavier Lima department of surgery Federal University of Minas GeraisBelo Horizonte 30130-100Minas GeraisBrazil Liver Transplantation Unit Felicio Rocho HospitalBelo Horizonte 30110-934Minas GeraisBrazil department of Morphology Federal University of Minas GeraisBelo Horizonte 31270-901Minas GeraisBrazil department of Biochemistry and Immunology Federal University of Minas GeraisBelo Horizonte 31270-901Minas GeraisBrazil department of Pathology Federal University of Minas GeraisBelo Horizonte 30130-100Minas GeraisBrazil

BACKGROUND Acute liver failure(ALF)is a severe condition characterized by rapid deterioration of liver function in individuals without preexisting liver *** transplantation(LT)is the most impactful *** fever(YF)is an infectious disease that primarily affects the liver and has a high mortality ***,LT can be a viable option for treating rare cases with extensive liver ***,the criteria for assessing the severity of ALF and determining the indications for transplantation have not been specifically validated for cases caused by *** To present necessary adjustments to established scoring systems for ALF secondary to *** This was an observational,retrospective,single-center *** consecutive patients with confirmed ALF due to YF were monitored in the intensive care unit by a specialized liver transplant team during a three-month epidemic outbreak in *** hospitalization,general supportive therapeutic measures were implemented,and the patients were regularly assessed using the King's College criteria and the Clichy-Villejuif criteria to determine the severity of liver *** is considered a viable measure for patients with signs of end-stage liver *** Eight of 14(57%)patients developed severe neurological alterations within the first 96 hours after hospital *** patients underwent emergency LT,and despite a moderate viral infection of the graft after transplantation,the 5-year survival rate was 50%.Although the King's College criteria and the Clichy-Villejuif criteria are the main scoring systems for ALF,they are insufficient for predicting the risk of mortality in this context,primarily because of low serum bilirubin levels in the final stage of the disease and significant disparities between coagulation abnormalities and patient *** To ensure good applicability in cases of YF-induced ALF,the authors suggest adaptations to the King's College and Clichy-Vill

关键词： Yellow fever Acute liver failure Liver transplantation King's College criteria Clichy-Villejuif criteria