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Flipped classroom approach to global outreach:cross-cultural teaching of horizontal strabismus to Chinese ophthalmology residents

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International Journal of Ophthalmology(English edition) 2023年第2期16卷 280-285页

作者： Randy Lu Ryan E Dodge Ⅲ Jocelyn Lam Laura Enyedi Tammy Yanovitch Nandini Gandhi leona ding Michelle T Cabrera University of Washington School of Medicine SeattleWA 98195USA Department of Anesthesia Massachusetts General HospitalBostonMA 02114USA Eyehealth Northwest PortlandOR 97209USA Department of Ophthalmology Duke UniversityDurhamNC 27708USA Department of Ophthalmology University of OklahomaOklahoma CityOK 73019USA Department of Ophthalmology University of California DavisSacramentoCA 95817USA Department of Ophthalmology University of WashingtonSeattleWA 98195USA Division of Ophthalmology Seattle Children’s HospitalSeattleWA 98105USA

AIM:To evaluate the flipped classroom model for teaching horizontal strabismus didactics in an ophthalmology residency program in China as part of a visiting professorship from the United ***:Residents from an ophthalmology residency program in China were invited to participate in flipped classroom sessions taught by an experienced American ophthalmology faculty in *** were instructed to watch a pre-class video lecture prior to the in-class-casebased *** tests(5 Ophthalmic Knowledge Assessment Program style questions)and surveys were administered before and after the classroom sessions(100%response rate).These results were compared to that of an American cohort who were taught the same ***:The Chinese cohort of 12 residents preferred the flipped classroom to the traditional classroom at higher rates than the American cohort of 40 residents(92%vs 55%,P=0.04)and felt that all ophthalmology topics would be appropriate for the flipped classroom teaching style(P-values between 0.008 and<0.001).In both Chinese and American cohorts,we found that the exotropia curriculum saw a small but significant improvement in performance following the flipped classroom session(P=0.025 for Chinese residents;P=0.001 for US residents),whereas scores in both groups for the esotropia course did not significantly ***:This is the first study to evaluate the flipped classroom model implemented by a visiting ophthalmology professor in a global outreach *** flipped classroom sessions are viewed favorably by the Chinese residents relative to the US cohort with a modest impact on *** in-person interpreter requirement and increased student engagement make this model valuable in cross-cultural visiting professorship ***,the flipped classroom may lend itself well to a virtual format to prevent the transmission of COVID-19,although such a format requires further study.

关键词： flipped classroom international ophthalmology residency graduate medical education China active learning medical education ophthalmology

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Survey of current retinopathy of prematurity practices in China

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International Journal of Ophthalmology(English edition) 2021年第8期14卷 1241-1247页

作者： Thao Phuong Le Jing Feng leona ding Rong Hu Xiao-Bo Lou J Niklas Ulrich Michelle T Cabrera Eye Associates Northwest P.C. SeattleWashington 98104-1306USA Department of Ophthalmology Beijing Chaoyang HospitalCapital Medical UniversityBeijing 100020China Department of Ophthalmology University of WashingtonSeattleWA 98195-0005USA Department of Ophthalmology Hunan People’s HospitalChangsha 410005Hunan ProvinceChina Department of Ophthalmology University of North CarolinaChapel HillNC 27515USA Department of Ophthalmology Seattle Children’s HospitalSeattleWA 98105USA

AIM:To understand retinopathy of prematurity(ROP)screening and treatment preferences among Chinese ***:A Chinese language survey was administered anonymously using Web Q(Catalyst,Seattle,WA,USA)among Chinese ROP screeners from December 2016 to January ***:Among 70 ophthalmologists contacted,65 responded(93%;78%female,mean age 40 y,57%pediatric ophthalmologists and 25%retina specialists).Most used screening criteria of birth weight≤2 kg(62%)with variation in cut-off gestational age(≤37 wk,34%;≤34 wk,22%;≤32 wk,31%).Ret Cam(Natus Medical Incorporated,Pleasanton,CA,USA)wide-field fundus photography assisted most screeners(72%)and was exclusively used by many(29%).Among 55 ophthalmologists treating ROP,anti-vascular endothelial growth factor(VEGF)was preferred over laser for both zoneⅠ(76%vs 24%)and zoneⅡROP(58%vs 42%).Retina specialists(P=0.004)and ophthalmologists with>3 mo of training(P=0.03)were more likely to use antiVEGF over laser for zoneⅠ*** of laser training(8/20,40%),access(6/20,30%)and anesthesia(4/20,20%)were common barriers to laser ***:Chinese ROP screeners favor antiVEGF injection and Ret Cam imaging for ROP management.A better understanding of ROP screening and treatment informs future research and education efforts in China.

关键词： pediatrics retina retinopathy of prematurity survey telemedicine

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A widely adaptable approach to generate integration-free iPSCs from non-invasively acquired human somatic cells

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Protein & Cell 2015年第5期6卷 386-389页

作者： Zhichao ding Lina Sui Ruotong Ren Yanjun Liu Xiuling Xu Lina Fu Ruijun Bai Tingting Yuan Ying Hao Weiqi Zhang Huize Pan Wensu Liu Han Yu Concepcion Rodriguez Esteban Xiaobing Yu Ze Yang Jian Li Xiaomin Wang Juan Carlos Izpisua Belmonte Guang-Hui Liu Fei Yi Jing Qu National Laboratory of Biomacromolecules Institute of Biophysics University of the Chinese Academy of Sciences Chinese Acad- emy of Sciences Beijing 100101 China Department of Endocrinology 306th Hospital of PLA Beijing100101 China Science and Development Xtem Foshan 528000 China State Key Laboratory of Reproductive Biology Institute of ZoologyChinese Academy of Sciences Beijing 100101 China Beijing Hospital of the Ministry of Health Beijing 100073 China Beijing Institute for Brain Disorders Beijing 100069 China Gene Expression Laboratory Salk Institute for Biological Studies10010 North Torrey Pines Road La Jolla CA 92037 USA Center for Molecular and Translational Medicine Beijing 100101China Department of Molecular and Cellular Physiology StanfordUniversity School of Medicine Stanford CA 94305 USA

Dear Editor Human pluripotent stem cells including human embryonic stem cells （ESCs） and induced pluripotent stem cells （iPSCs） are cells displaying abilities of unlimited self-renewal and differentiation into any somatic cell type. These unique properties make them increasingly attractive for novel applications in disease modeling, drug discovery, and cell therapy （Buganim et al., 2014; Liu et al., 2011; Liu et al., 2012; Sanchez Alvarado and Yamanaka, 2014）. Moreover, iPSCs hold great potential for personalized cell therapy as they avoid some of the ethical concerns as well as the immunological rejection issues ascribed to ESCs.

关键词： iPSC dbcAMP Definitive Endoderm Cell Reprogram iPSC Line

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Direct reprogramming of porcine fibroblasts to neural progenitor cells

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Protein & Cell 2014年第1期5卷 4-7页

作者： Xiu-Ling Xu Ji-Ping Yang Li-Na Fu Ruo-Tong Ren Fei Yi Keiichiro Suzuki Kai Liu Zhi-Chao ding Jing Qu Wei-Qi Zhang Ying Li Ting-Ting Yuan Guo-Hong Yuan Li-Na Sui Di Guan Shun-Lei Duan Hui-Ze Pan Ping Wang Xi-Ping Zhu Nuria Montserrat Ming Li Rui-Jun Bai Lin Liu Juan Carlos lzpisua Belmonte Guang-Hui Liu National Laboratory of Biomacromolecules Institute of BiophysicsChinese Academy of Sciences Department of Molecular and Cellular Physiology tanford University School of MedicineStanfordCA 94305USA Gene Expression Laboratory Salk Institute for Biological Studies10010 North Torrey Pines RoadLa JollaCA 9207USA State Key Laboratory of Medicinal Chemical Biology College of Life SciencesNankai University Center for Regenerative Medicine in Barcelona Dr.Aiguader 8808003 BarcelonaSpain Beijing Institute for Brain Disorders

Dear Editor,Neural progenitor cells(NPCs)have proven potential to facilitate mechanistic studies of neurological disorders in vitro,as well as the discovery of new *** addition,NPCs have been proposed as promising cell sources for cell replacement therapy of neurological diseases(Liu et al.,2012b).For these areas of study,experimental animals are indispensable *** the possible animal species,pigs are advantageous compared to rodents because of their physiological and anatomical similarities to

关键词： Neural Progenitor Cell Neural Differentiation Sodium Butyrate Direct Reprogram Episomal Vector

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