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Extended Lorenz majorization and frequencies of distances in an undirected network

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Journal of Data and Information Science 2024年第1期9卷 1-10页

作者： leo Egghe Hasselt University Diepenbeek 3590Belgium

Purpose:To contribute to the study of networks and ***/methodology/approach:We apply standard mathematical ***:We show that the distance distribution in an undirected network Lorenz majorizes the one of a *** a consequence,the average and median distances in any such network are smaller than or equal to those of a *** limitations:We restricted our investigations to undirected,unweighted *** implications:We are convinced that these results are useful in the study of small worlds and the so-called six degrees of separation ***/value:To the best of our knowledge our research contains new network results,especially those related to frequencies of distances.

关键词： majorization Lorenz curves networks shortest path distance graphs

Adenosine A_(2A)receptor blockade attenuates excitotoxicity in rat striatal medium spiny neurons during an ischemic-like insult

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Neural Regeneration Research 2024年第2期19卷 255-257页

作者： elisabetta Coppi Federica Cherchi Alasdair J.Gibb Department of Neuroscience PsychologyDrug Research and Child HealthUniversity of FlorenceFlorenceItaly Department of Neuroscience Physiology and PharmacologyUniversity College LondonLondonUK

During brain ischemia,excitotoxicity and peri-infarct depolarization injuries occur and cause cerebral tissue ***,anoxic depolarization,consisting of massive neuronal depolarization due to the loss of membrane ion gradients,occurs in vivo or in vitro during an energy *** neuromodulator adenosine is released in huge amounts during cerebral ischemia and exerts its effects by activating specific metabotropic receptors,namely:A_(1),A_(2A),A_(2B),and A_(3).The A_(2A)receptor subtype is highly expressed in striatal medium spiny neurons,which are particularly susceptible to ischemic *** indicates that the A2Areceptors are upregulated in the rat striatum after stroke and the selective antagonist SCH58261 protects from exaggerated glutamate release within the first 4 hours from the insult and alleviates neurological impairment and histological injury in the following 24 *** recently added new knowledge to the mechanisms by which the adenosine A2Areceptor subtype participates in ischemia-induced neuronal death by performing patch-clamp recordings from medium spiny neurons in rat striatal brain slices exposed to oxygen and glucose *** demonstrated that the selective block of A2Areceptors by SCH58261 significantly reduced ionic imbalance and delayed the anoxic depolarization in medium spiny neurons during oxygen and glucose deprivation and that the mechanism involves voltage-gated K+channel modulation and a presynaptic inhibition of glutamate release by the A2Areceptor *** present review summarizes the latest findings in the literature about the possibility of developing selective ligands of A2Areceptors as advantageous therapeutic tools that may contribute to counteracting neurodegeneration after brain ischemia.

关键词： adenosine A_(2A)receptors anoxic depolarization brain ischemia glutamate excitotoxicity medium spiny neurons oxygen and glucose deprivation

Enhanced Hoek-Brown(H-B)criterion for rocks exposed to chemical corrosion

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International Journal of Mining Science and Technology 2024年第5期34卷 609-630页

作者： Hao Li leo Pel Zhenjiang You David Smeulders Department of Mechanical Engineering Eindhoven University of TechnologyEindhoven 5600 MBthe Netherlands Department of Applied Physics Eindhoven University of TechnologyEindhoven 5600 MBthe Netherlands Center for Sustainable Energy and Resources School of EngineeringEdith Cowan UniversityJoondalupWA 6027Australia School of Chemical Engineering The University of QueenslandBrisbaneQLD 4072Australia Gas and Energy Transition Research Centre The University of QueenslandBrisbaneQLD 4072Australia

Underground constructions often encounter water environments,where water–rock interaction can increase porosity,thereby weakening engineering ***,the failure criterion for chemically corroded rocks becomes essential in the stability analysis and design of such *** study enhances the applicability of the Hoek-Brown(H-B)criterion for engineering structures operating in chemically corrosive conditions by introducing a kinetic porosity-dependent instantaneous mi(KPIM).A multiscale experimental investigation,including nuclear magnetic resonance(NMR),X-ray diffraction(XRD),scanning electron microscopy(SEM),pH and ion chromatography analysis,and triaxial compression tests,is employed to quantify pore structural changes and their linkage with the strength responses of limestone under coupled chemical-mechanical(C-M)*** employing ion chromatography and NMR analysis,along with incorporating the principles of free-face dissolution theory accounting for both congruent and incongruent dissolution,a kinetic chemical corrosion model is *** model aims to calculate the kinetic porosity alterations within rocks exposed to varying H+concentrations and ***,utilizing the generalized mixture rule(GMR),the kinetic porositydependent mi is *** of the KPIM-enhanced H-B criterion using compression test data from 5 types of rocks demonstrated a high level of consistency between the criterion and the experimental results,with a coefficient of determination greater than 0.96,a mean absolute percentage error less than 4.84%,and a root-mean-square deviation less than 5.95 ***,the physical significance of the porosity-dependent instantaneous mi is clarified:it serves as an indicator of a rock’s capacity to leverage the confining pressure effect.

关键词： Hoek-Brown(H-B)criterion Instantaneous mi Kinetic porosity-dependency Chemical corrosion Compressive strength

Covid-19 vaccination in pregnancy and placental pathology

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Asian pacific Journal of Reproduction 2024年第2期13卷 76-79页

作者： leo Simanjuntak Department of Obstetrics and Gynecology Faculty of MedicineUniversitas HKBP NommensenMedanIndonesia

Objective:To describe and determine the association between Covid-19 vaccination in pregnancy and placental ***:Conducted in a tertiary hospital in Medan,Indonesia,from April 30th 2022 to June 30th 2022,this single-center cross-sectional study involved Covid-19 vaccinated and unvaccinated women with singleton full-term pregnancies delivering live fetuses via cesarean *** characteristics,placental pathologies,and the placental index were documented at *** association between Covid-19 vaccination status and placental pathology was ***:The study enrolled 200 pregnant women,including 110 vaccinated women and 90 unvaccinated *** significant differences were observed in birthweight(P=0.48),placental index(P=0.48),and placental pathology findings[intervillous bleeding(P=0.20),increased syncytial knots(P=0.83),chorangiosis(P=0.13),villous stromal edema(P=0.13),vascular dilation and congestion(P=0.13),and vascular wall thrombus(P=0.71)]between the vaccinated and unvaccinated ***:This study revealed no statistically significant association between Covid-19 vaccination and placental *** findings support the safety of Covid-19 vaccination during pregnancy,in regards to changes of the placental pathology.

关键词： Covid-19 Vaccination Pregnancy Women Placenta

从热力学计算到定形体系的实验表征设计全金属复合相变材料

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Transactions of Nonferrous Metals Society of China 2024年第5期34卷 1393-1412页

作者： Chiara CONFALONIERI Alessandra CAMNAGHI elisabetta GARIBOLDI Politecnico di Milano Department of Mechanical EngineeringVia La Masa 120156 MilanItaly

用于热能管理的复合相变材料(C-PCMs)利用其一个或多个低熔点活性相的可逆相变(如熔化—凝固)存储和释放热能作为潜热。同时,高熔点的惰性相可以提供额外的性能,如定形性和改善的导热性。从难混溶合金中可获得具有这些特征的全金属复合... 详细信息

用于热能管理的复合相变材料(C-PCMs)利用其一个或多个低熔点活性相的可逆相变(如熔化—凝固)存储和释放热能作为潜热。同时,高熔点的惰性相可以提供额外的性能,如定形性和改善的导热性。从难混溶合金中可获得具有这些特征的全金属复合材料体系。本文将热力学计算和实验测试相结合,探讨二元(Al-In,Al-Sn,Al-Bi和Cu-Bi)和三元(Al-In-Sn和Al-Bi-Sn)难混溶合金在100~300℃的温度范围内用作C-PCMs的潜力。结果表明,将这两种方法相结合对于全面理解复合体系和找到满足设计需求的最佳解决方案十分必要,它克服了“试错”法浪费时间的弊端,并为模拟提供了高质量的数据。

关键词：复合相变材料合金设计热力学性能定形性储热

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Removing Splitting/Modeling Error in Projection/Penalty Methods for Navier-Stokes Simulations with Continuous Data Assimilation

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Communications in Mathematical Research 2024年第1期40卷 1-29页

作者： Elizabeth Hawkins leo G.Rebholz Duygu Vargun Department of Mathematical Sciences Clemson UniversityClemsonSC 29634USA

We study continuous data assimilation(CDA)applied to projection and penalty methods for the Navier-Stokes(NS)*** and projection methods are more efficient than consistent Ns discretizations,however are less accurate due to modeling error(penalty)and splitting error(projection).We show analytically and numerically that with measurement data and properly chosen parameters,CDA can effectively remove these splitting and modeling errors and provide long time optimally accurate solutions.

关键词： Navier-Stokes equations projection method penalty method continuous data assimilation

Does the provision of live black soldier fly and yellow mealworm larvae improve Muscovy duck welfare?

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Journal of Animal Science and Biotechnology 2024年第1期15卷 442-455页

作者： Marta Gariglio Sihem Dabbou Manuela Renna Ilaria Biasato Sara Bellezza Oddon Marco Meneguz Raul Daniel Miazzo Stefania Bergagna Elena Colombino elisabetta Macchi Achille Schiavone Department of Veterinary Sciences University of TurinLargo Paolo Braccini 2GrugliascoTorino(TO)10095Italy Center Agriculture Food Environment(C3A) University of TrentoVia Edmund Mach 1San Michele All’AdigeTrento(TN)38098Italy Department of Agricultural Forest and Food SciencesUniversity of TurinLargo Paolo Braccini 2GrugliascoTorino(TO)10095Italy BEF Biosystems s.r.l Via Tancredi Canonico 18/CTorino(TO)10156Italy Unidad de Investigacion Aviar Produccion AvicolaFac.Agr.y Vet.Universidad Nacional de Rio CuartoCordobaArgentina Veterinary Medical Research Institute for Piemonte Liguria and Valle d’AostaVia Bologna 148Torino(TO)10154Italy

Background The provision of environmental enrichments to Muscovy ducks could reduce the expression of the aggressive *** aim of the present study was to evaluate the effects of black soldier fly(BSF)and yellow mealworm(YM)live larva provision on Muscovy duck performance,excreta corticosterone metabolites(ECM),behavior,and blood *** A total of 1263-day-old female Muscovy ducklings were allotted to 18 pens(6 replicates/treatment,7 birds/pen)and assigned to 3 experimental treatments:a control group fed commercial feed,and two experimental treatments fed commercial feed plus the 5%(based on the expected daily feed intake,as fed basis)of BSF and YM live larvae(BSF and YM groups,respectively).A two-phase feeding program was applied:starter(from 3 to 31 days of age)and grower-finisher(from 32 to 55 days of age).The live weight,average daily gain,average daily feed intake,and feed conversion ratio were *** consumption times were collected,and video recordings were performed during 3 periods(P)each day:the hour before(P1),during(P2),and after(P3)the larva *** were evaluated at 3,31,and ***,the total red and white blood cell counts,serum proteins,lipids,and liver and renal function serum enzymes were evaluated on 12 birds/*** The experimental treatment did not affect the growth performance of the birds(P>0.05).Larva consumption times were always similar between the two insect species,except at 14–18 days of age,were BSF larvae were consumed faster than YM larvae(PP3;P<0.05).Finally,the provision of live BSF and YM larvae significantly reduced the ECM at 55 days of age and the heterophil to lymphocyte ratio(P<0.05).Conclusions Live BSF and YM larva supplementatio

关键词： Behavior Cairina moschata Environmental enrichment Hermetia illucens Poultry Tenebrio molitor Welfare

Crystalline cyclic(alkyl)(amino)stannylene via transient stannyne

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Science China Chemistry 2024年

作者： Xinfeng Wang Chaopeng Hu Zhihao Lu Liu leo Liu Department of Chemistry and Research Center for Chemical Biology and Omics Analysis College of Science Southern University of Science and Technology

We demonstrate that a bulky cyclic amino ligand, specifically 1,1,3,3-tetraphenylisoindolinyl, can facilitate the formation of a transient stannyne, endowed with adjacent ambiphilic carbon and tin centers. This stannyne, manifesting carbene-like behavior,engages in an unprecedented sequence of reactions, including Buchner ring expansion, [1,3]sigmatropic, and [1,5]-sigmatropic shifts, culminating in the synthesis of a stable cyclic(alkyl)(amino)stannylene. This compound represents the first tin analogue of the well-known cyclic(alkyl)(amino)carbenes. Both the bonding configuration and the formation process of this stannylene are thoroughly analyzed through quantum chemical computations. Our findings pave the way for further synthesis of unusual main group species using bulky isoindolinyl substituents, emphasizing their potential as a versatile tool in synthetic chemistry.

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Multifaceted superoxide dismutase 1 expression in amyotrophic lateral sclerosis patients:a rare occurrence?

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Neural Regeneration Research 2025年第1期20卷 130-138页

作者： Ilaria Martinelli Jessica Mandrioli Andrea Ghezzi elisabetta Zucchi Giulia Gianferrari Cecilia Simonini Francesco Cavallieri Franco Valzania Department of Neurosciences Azienda Ospedaliero Universitaria di ModenaModenaItaly Clinical and Experimental Medicine Ph.D.Program University of Modena and Reggio EmiliaModenaItaly Department of Biomedical Metabolic and Neural SciencesUniversity of Modena and Reggio EmiliaModenaItaly Neurology Unit Neuromotor&Rehabilitation DepartmentAzienda USL-IRCCS di Reggio EmiliaReggio EmiliaItaly

Amyotrophic lateral sclerosis(ALS)is a neuromuscular condition resulting from the progressive degeneration of motor neurons in the cortex,brainstem,and spinal *** the typical clinical phenotype of ALS involves both upper and lower motor neurons,human and animal studies over the years have highlighted the potential spread to other motor and non-motor regions,expanding the phenotype of *** superoxide dismutase 1(SOD1)mutations represent a minority of ALS cases,the SOD1 gene remains a milestone in ALS research as it represents the first genetic target for personalized *** numerous single case reports or case series exhibiting extramotor symptoms in patients with ALS mutations in SOD1(SOD1-ALS),no studies have comprehensively explored the full spectrum of extramotor neurological manifestations in this *** this narrative review,we analyze and discuss the available literature on extrapyramidal and non-motor features during *** multifaceted expression of SOD1 could deepen our understanding of the pathogenic mechanisms,pointing towards a multidisciplinary approach for affected patients in light of new therapeutic strategies for SOD1-ALS.

关键词： amyotrophic lateral sclerosis(ALS) autonomic extramotor genotype-phenotype multisystem involvement Parkinson’s disease sensory SOD1 superoxide dismutase 1 urinary vocal cord palsy