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Ten decadal advances in fungal biology leading towards human well‑being

Fungal Diversity 2022年第5期116卷 547-614页

作者： Ausana Mapook·Kevin DHyde Kevin D.Hyde Khadija Hassan Blondelle Matio Kemkuignou Adela Cmokova Frank Surup Eric Kuhnert Pathompong Paomephan Tian Cheng Sybren de Hoog Yinggai Song Ruvishika S.Jayawardena Abdullah M.S.Al‑Hatmi Tokameh Mahmoudi Nadia Ponts lena studt‑reinhold Florence Richard‑Forget K.W.Thilini Chethana Dulanjalee L.Harishchandra Peter E.Mortimer Huili Li Saisamorm Lumyong Worawoot Aiduang Jaturong Kumla Nakarin Suwannarach Chitrabhanu S.Bhunjun Feng‑Ming Yu Qi Zhao Doug Schaefer Marc Stadler Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand Department Microbial Drugs Helmholtz Centre for Infection Research(HZI)and German Centre for Infection Research(DZIF)Partner Site Hannover‑BraunschweigInhoffenstrasse 738124 BrunswickGermany Institute of Microbiology Technische Universitat BraunschweigSpielmannstrase 738106 BrunswickGermany Laboratory of Fungal Genetics and Metabolism Institute of MicrobiologyCzech Academy of SciencesPragueCzech Republic Centre of Biomolecular Drug Research(BMWZ) Institute for Organic ChemistryLeibniz University HannoverSchneiderberg 3830167 HannoverGermany Department of Biotechnology Faculty of ScienceMahidol University272 Rama VI RoadRatchathewiBangkok 10400Thailand Center of Expertise in Mycology Radboud University Medical Center/Canisius Wilhelmina HospitalNijmegenThe Netherlands Key Laboratory of Environmental Pollution Monitoring and Disease Control Guizhou Medical UniversityGuiyangChina Microbiology Parasitology and Pathology Graduate ProgramFederal University of ParanaCuritibaBrazil Department of Dermatology Peking University First HospitalPeking UniversityBeijingChina Natural and Medical Sciences Research Center University of NizwaNizwaOman Department of Biochemistry Erasmus University Medical CenterRotterdamThe Netherlands INRAE UR1264 Mycology and Food Safety(MycSA)33882 Villenave d’OrnonFrance Department of Applied Genetics and Cell Biology Institute of Microbial GeneticsUniversity of Natural Resources and Life SciencesVienna(BOKU)Tulln an der DonauAustria Beijing Key Laboratory of Environment Friendly Management on Fruit Diseases and Pests in North China Institute of Plant ProtectionBeijing Academy of Agriculture and Forestry SciencesBeijing 100097China Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of SciencesKunming 650201YunnanChina Centre for Mountai

Fungi are an understudied resource possessing huge potential for developing products that can greatly improve human *** the current paper,we highlight some important discoveries and developments in applied mycology and interdisciplinary Life Science *** examples concern recently introduced drugs for the treatment of infections and neurological diseases;application of–OMICS techniques and genetic tools in medical mycology and the regulation of mycotoxin production;as well as some highlights of mushroom cultivaton in *** for new diagnostic tools in medical mycology and the exploitation of new candidates for therapeutic drugs,are also *** addition,two entries illustrating the latest developments in the use of fungi for biodegradation and fungal biomaterial production are *** other areas where there have been and/or will be significant developments are also *** is our hope that this paper will help realise the importance of fungi as a potential industrial resource and see the next two decades bring forward many new fungal and fungus-derived products.

关键词： Biomaterial CRISPR Drug development Morel cultivation Mushroom cultivation Mycotoxin biosynthesis Plastic degradation

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