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Syncope as a health risk for soldiers: Influence of medical history and clinical findings on the sensitivity of head-up tilt table testing

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Journal of Medical Colleges of PLA(China) 2015年第2期30卷 82-90页

作者： Hans-Joachim Gilfrich lena Marie Heidelmann Franziska Grube Hagen Frickmann Sven Andreas Jungblut The Practice of Dr.Jungblut Frankfurt/Main The Flight Medicine Clinic at Fassberg German Armed Forces The Department of Tropical Medicine at the Bernhard Nocht Institute German Armed Forces Hospital of Hamburg The Department of Microbiology Virology and HygieneUniversity Medicine Rostock

Background: Syncope is a relevant health problem in military environments. Reliable diagnosis is challenging. Tilt table testing is an important tool for syncope diagnosis. The aim of this study was to determine whether signs such as prodromal symptoms, co-morbidity, frequency of syncopal events, body length, body mass index, and electrocardiography(ECG) abnormalities can be used to predict the success of tilt table testing at diagnosing ***: Data from 100 patients with histories of syncope or pre-syncope, who were diagnosed using head-up tilt table testing, were retrospectively analyzed in a cross-sectional analysis. The diagnostic procedure was based upon a modified version of the Westminster protocol without any pharmacological provocation. Results: Patients showing pathological reaction patterns during tilt table testing suffered from prodromal symptoms, such as dizziness and sweating, significantly more often. The patients reported more injuries resulting from syncopal events and more previous syncopal events, and the prevalence of co-morbidity was greater among patients presenting negative findings during tilt testing. An asthenic-leptosomal physique was not confirmed as a risk factor for syncopal events as is the case for idiopathic arterial hypotension. However, patients with pathological reaction patterns during tilt table testing were significantly taller. This finding was detected for both females and males. No significant predictors were found in the ECG patterns of patients showing syncope during tilt table ***: Frequency of prior syncope and prodromal symptoms, and increased body length with an otherwise good state of health influence the predictive value of tilt table testing for syncope diagnosis. In particular, if these factors are present, tilt table testing should be considered part of the diagnostic algorithm for soldiers with recurrent syncope.

关键词： Syncope Head-up tilt testing Predictor Soldiers Assessment Hypotension

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旧功夫

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电影评介 2005年第10期 15-18页

作者： lena

还在琢磨佐罗再次挥鞭的英姿?要知道,温故才可以知新啊!漂亮的一记勾拳击中下颚,在挤满人的闹市区玩极速赛车——今天的动作电影中,刺激的场面变得更大、更炫——特别是体现在DVD上。你可以重复重复再重复地回放令自己血脉贲张的动作片... 详细信息

还在琢磨佐罗再次挥鞭的英姿?要知道,温故才可以知新啊!漂亮的一记勾拳击中下颚,在挤满人的闹市区玩极速赛车——今天的动作电影中,刺激的场面变得更大、更炫——特别是体现在DVD上。你可以重复重复再重复地回放令自己血脉贲张的动作片段,正是那些或花拳秀腿、或硬桥硬马的经典动作场面,让你即便在梦里也会激动得拳打脚踢。所以,坐稳了,扣紧安全带,让我们一起体验动作电影的巅峰时刻,怀念那些旧功夫。

关键词：电影动作功夫闹市区重复拳击安全带下颚回放赛车

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Novel intelligent devices: Two-dimensional materials based memristors

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Frontiers of physics 2022年第2期17卷 83-85页

作者： lena Du Zhongchang Wang Guozhong Zhao Department of Physics Capital Normal UniversityBeijing 100048China International Iberian Nanotechnology Laboratory(INL)Avenida Mestre JoséVeiga s/n Braga 4715-330Portugal

Two-dimensional(2D)materials with atomic thickness,non-volatile resistive switching feature and compatibility with the semiconducting technology are naturally a good media of memristors.2D materials-based memristors with excellent performance,low-power consumption and high integration density can be integrated with other circuit components to implement the complicate logic computing,which will become a key driving force for the development of artificial intelligence.

关键词： artificial memristor driving

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SUSTAINABLE NITROGEN MANAGEMENT INDEX: DEFINITION, GLOBAL ASSESSMENT AND POTENTIAL IMPROVEMENTS

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Frontiers of Agricultural Science and Engineering 2022年第3期9卷 356-365页

作者： Xin ZHANG Yanyu WANG lena SCHULTE-UEBBING Wim DE VRIES Tan ZOU Eric ADAVIDSON University of Maryland Center for Environmental Science FrostburgMD 21532USA Environmental Systems Analysis Group Wageningen University&ResearchWageningen6708 PBthe Netherlands PBL Netherlands Environmental Assessment Agency The Hague2594 AVthe Netherlands.

To represent the sustainability of nitrogen management in the Sustainable Development Goals indicator framework,this paper proposes a sustainable nitrogen management index(SNMI).This index combines the performance in N crop yield and N use efficiency(NUE),thereby accounting for the need for both food production and environmental *** SNMI to countries around the world,the results showed improvement in the overall sustainability of crop N management over the past four decades,but this improvement has been mainly achieved by crop yield increase,while global NUE has improved only *** values vary largely among countries,and this variation has increased since the 1970s,implying different levels of success,even failure,in improving N management for countries around the *** the standard SNMI assessment,the reference NUE was defined as 1.0(considered an ideal NUE)and the reference yield was defined as 90 kg·ha^(−1)·yr^(−1) N(considering a globally averaged yield target for meeting food demand in 2050).A sensitivity test that replaced the reference NUE of 1.0 with more realistic NUE targets of 0.8 or 0.9 showed overall reduction in SNMI values(i.e.,improved performance),but little change in the ranking among *** another test that replaced the universal reference yield with region-specific attainable yield,SNMI values declined(i.e.,improved performance)for most countries in Africa and West Asia,whereas they increased for many countries in Europe and South *** index can be improved by further investigation of approaches for setting region-specific yield targets and high-quality data on crop yield ***,SNMI offers promise for a simple and transparent approach to assess progress of countries toward sustainable N management with a single indicator.

关键词： global assessment indicator nitrogen management sustainable agriculture sustainable development goals

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The Nordic geological surveys： Geology for society in practice

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Episodes 2008年第1期31卷 193-200页

作者： Morten Smelror Andreas AhlstrФm lena Ekelund Jens Morten Hansen Keijo Nenonen Anette K. Mortensen Geological Survey of Norway （NGU） Leiv Eirikssons vei 39 NO-7491 Trondheim Norway. Geological Survey of Denmark and Greenland （GEUS） Фster Voldgade 10 DK-1350 KCbenhavn K Denmark. Geological Survey of Sweden （SGU） Box 670 S-751 28 Uppsala Sweden. Geological Survey of Finland （GTK） P.O. Box 96 FI-02151 Espoo Finland. Iceland Geosurvey （ISOR） Grensaisvegi 9 108 Reykjavfk.Ucekabd.

Since the mid-nineteenth century., when the first of the Nordic Geological Surveys were established, they have generated a substantial amount of information on the Earth＇s crust, its natural resources, its processes, and on the geological history of Nordic areas. The collective mission of the geological surveys is to carry out ＂Geology for Society＂, by doing research and providing services, and by making geological information and data easily accessible to all the varied end users in industry, government agencies, government institutes, public administrations, technical offices, academia and research institutes, as well as for private individuals. The present paper gives a brief overview of a few, selected, research areas and projects currently undertaken by the Nordic geological surveys. These serve as practical examples of how the Nordic geological surveys address important societal problems and challenges that require geological input for their solution.

关键词：地质学测量北欧地区社会实践公共管理

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Recent trends in liver transplantation for alcoholic liver disease in the United States

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World Journal of Hepatology 2017年第36期9卷 1315-1321页

作者： Catherine E Kling James D Perkins Robert L Carithers Dennis M Donovan lena Sibulesky Division of Transplant Surgery Department of Surgery University of Washington Division of Gastroenterology and Hepatology Department of Medicine University of Washington Department of Psychiatry and Behavioral Sciences University of Washington

AIM To examine temporal changes in the indications for liver transplantation(LT) and characteristics of patients transplanted for alcoholic liver disease(ALD).METHODS We performed a retrospective cohort analysis of trends in the indication for LT using the United Network for Organ Sharing(UNOS) database between 2002 and 2015. Patients were grouped by etiology of the liver disease and characteristics were compared using χ~2 and t-tests. Time series analysis was used identifying any year with a significant change in the number of transplants per year for ALD, and before and after eras were modeled using a general linear model. Subgroup analysis of recipients with ALD was performed by age group, gender, UNOS region and etiology(alcoholic cirrhosis, alcoholic hepatitis and hepatitis C-alcoholic cirrhosis dual listing).RESULTS Of 74216 liver transplant recipients, ALD(n = 9400, 12.7%) was the third leading indication for transplant after hepatitis C and hepatocellular carcinoma. Transplants for ALD, increased from 12.8%(553) in 2002 to 16.5%(1020) in 2015. Time series analysis indicated a significant increase in the number of transplants per year for ALD in 2013(P = 0.03). There were a stable number of transplants per year between 2002 and 2012(linear coefficient 3, 95%CI:-4.6, 11.2) an increase of 177 per year between 2013 and 2015(95%CI: 119, 234). This increase was significant for all age groups except those 71-83 years old, was observed for both genders, and was incompletely explained by a decrease in transplants for hepatitis C and ALD dual listing. All UNOS regions except region 9 saw an increase in the mean number of transplants per year when comparing eras, and this increase was significant in regions 2, 3, 4, 5, 6, 8, 10 and *** There has been a dramatic increase in the number of transplants for ALD starting in 2013.

关键词： Alcoholic liver disease Liver transplantation Cirrhosis Epidemiology Hepatitis C

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Bone without borders-Monetite-based calcium phosphate guides bone formation beyond the skeletal envelope

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Bioactive Materials 2023年第1期19卷 103-114页

作者： Furqan A.Shah Martina Jolic Chiara Micheletti Omar Omar Birgitta Norlindh lena Emanuelsson Håkan Engqvist Thomas Engstrand Anders Palmquist Peter Thomsen Department of Biomaterials Sahlgrenska AcademyUniversity of GothenburgGothenburgSweden Department of Materials Science and Engineering McMaster UniversityHamiltonOntarioCanada Department of Engineering Sciences Applied Materials Science SectionUppsala UniversityUppsalaSweden Department of Reconstructive Plastic Surgery Karolinska University HospitalStockholmSweden

Calcium phosphates(CaP)represent an important class of osteoconductive and osteoinductive *** proof-of-concept,we show how a multi-component CaP formulation(monetite,beta-tricalcium phosphate,and calcium pyrophosphate)guides osteogenesis beyond the physiological *** a sheep model,hollow dome-shaped constructs were placed directly over the occipital *** 12 months,large amounts of bone(~75%)occupy the hollow space with strong evidence of ongoing *** of both compact bone(osteonal/osteon-like arrangements)and spongy bone(trabeculae separated by marrow cavities)reveal insights into function/need-driven microstructural *** within the CaP also contain both woven bone and vascularised lamellar *** actively contribute to CaP degradation/*** the constituent phases,only calcium pyrophosphate persists within osseous(cutting cones)and non-osseous(macrophages)*** a translational perspective,this multi-component CaP opens up exciting new avenues for osteotomy-free and minimally-invasive repair of large bone defects and augmentation of the dental alveolar ridge.

关键词： Bone Calcium phosphate Monetite Calcium pyrophosphate Electron microscopy Raman spectroscopy

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TURKISH DELIGHTS Middle Eastern tastes are taking over

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城市漫步（GBA版） 2014年第11期 60-61页

作者： lena GIDWANI JOCELYN RICHARDS 不详

There's a common saying amongst those who frequent Turkey that they often go for the history but stay for the *** cuisine is a stunning story of culinary layers upon layers,adapted and merged on the table into a whole,and expanded over time as the Turks went from Asian horse people to the founders of one of history's greatest empires.

关键词： Eastern Middle horse

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Bcl-2 degradation is an additional pro-apoptotic effect of polo-like kinase inhibition in cholangiocarcinoma cells

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World Journal of Gastroenterology 2017年第22期23卷 4007-4015页

作者： Svenja Sydor Sami Jafoui lena Wingerter Sandra Swoboda Joachim C Mertens Guido Gerken Ali Canbay Andreas Paul Christian D Fingas Department of Gastroenterology and Hepatology University Hospital EssenUniversity Duisburg-Essen Department for General Visceral and Transplantation SurgeryUniversity Hospital EssenUniversity Duisburg-Essen Division of Gastroenterology and Hepatology University Hospital Zurich

To examine the influence on apoptotic mechanisms following inhibition of polo-like kinases as therapeutically approach for cholangiocellular cancer *** most cholangiocarcinomas are chemotherapy-resistant due to mechanisms preventing tumor cell death, we investigated the effect of Cisplatin on cholangiocellular carcinoma (CCA) cell lines KMCH-1 and Mz-Ch-1. Polo-like kinases (PLK) are important regulators of the cell cycle and their inhibition is discussed as a potential therapy while PLK inhibition can regulate apoptotic mediators. Here, cells were treated with PLK inhibitor BI6727 (Volasertib), Cisplatin, and in combination of both compounds. Cell viability was assessed by MTT; apoptosis was measured by DAPI staining and caspase-3/-7 assay. Western blot and qRT-PCR were used to measure expression levels of apoptosis-related molecules Bax and *** cell viability in the CCA cell lines KMCH-1 and Mz-Ch-1 was reduced in all treatment conditions compared to vehicle-treated cells. Co-treatment with BI6727 and cisplatin could even enhance the cytotoxic effect of cisplatin single treatment. Thus, co-treatment of cisplatin with BI6727 could slightly enhance the cytotoxic effect of the cisplatin in both cell lines whereas there was evidence of increased apoptosis induction solely in Mz-Ch-1 as compared to KMCH-1. Moreover, PLK inhibition decreases protein levels of Bcl-2; an effect that can be reversed by the proteasomal degradation inhibitor MG-132. In contrast, protein levels of Bax were not found to be altered by PLK inhibition. These findings indicate that cytotoxic effects of Cisplatin in Mz-Ch-1 cells can be enhanced by cotreatment with *** conclusion, BI6727 treatment can sensitize CCA cells to cisplatin-induced apoptosis with proteasomal Bcl-2 degradation as an additional pro-apoptotic effect.

关键词： Tumor necrosis factor-related apoptosis-inducing ligand Myeloid cell leukemia-1 Hedgehog pathway Cisplatin Chemotherapy resistance

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The Chosen Buns Guangzhou’s Newest Bakeries Put to the Test

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城市漫步（GBA版） 2016年第7期 54-57页

作者： JOCELYN RICHARDS lena GIDWANI 不详

You read it here:it’s completely normal-commendable,even-to lose sleep over cravings for a loaf of just-baked sourdough coated in creamy,salted butter or rows of chunky,dark chocolate-chip cookies rising seductively in the *** goods are heavenly when done right,but how many bakeries here in Guangzhou actually know the difference between a bagel and a baguette?This month,we visited,tasted and ranked six new pastry shops in the city according to breadth of selection,quality and overall vibe.A‘breattitude’of four or higher definitely warrants a visit:knead we say more?

关键词： ranked Guangzhou definitely

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